Use of Erythromycin in Mustard-Induced Bronchiolitis

Inclusion Criteria: Documented chemical exposure Clinical, spirometric and radiological findings were compatible with BO on High Resolution Computed Tomography (HRCT) Non-responsiveness to high dose bronchodilator therapy Exclusion Criteria: Radiographic evidence of pneumonia, active tuberculosis, lung carcinoma, or an infection that necessitated the use of an antibiotic History of cigarette smoking and occupational exposure to toxic agents of hypersensitivity to macrolides History of treatment with a systemic antibiotic within 7 days before the start of the study Any investigational medicine within 4 weeks of the study History of antibiotic injection within 6 weeks before the study Concomitant Theophylline or Carbamazepine, unless their serum concentrations were regularly monitored Patients who were in the exacerbation phase of their respiratory complications Need to use medications interact with macrolides such as Digoxin, Theophylline and Carbamazepine Systemic antibiotics Systemic Corticosteroids Admission to the hospital Abnormal kidney or liver function