Back to resultsDandelion Juice in the Treatment of Dyshidrotic Hand Eczema
Primary Purpose
Vesicular Palmoplantar Eczema, Pompholyx
Status
Completed
Phase
Not Applicable
Locations
Denmark
Study Type
Interventional
Intervention
dandelion juice
Sponsored by
About this trial
This is an interventional treatment trial for Vesicular Palmoplantar Eczema focused on measuring Dandelion, herbal remedy, hand eczema, Compositae
Eligibility Criteria
Inclusion Criteria:
- Adult patients with dyshidrotic eczema for at least 1 year and negative patch test reactions to Compositae (tested within the last 3 years) and normal renal and hepatic blood tests.
Exclusion Criteria:
- Treatment with systemic steroids or other immunosuppressive/-modulating drugs, including UV therapy, within the last 3 months.
- Pregnancy, lactation.
- Compositae contact allergy.
- Liver or gall bladder disease.
- Abnormal renal or hepatic blood tests.
Sites / Locations
- Department of Dermatology, Odense University Hospital
Arms of the Study
Arm 1
Arm Type
Other
Arm Label
10 ml of dandelion juice twice daily
Arm Description
Outcomes
Primary Outcome Measures
Improvement in dyshidrotic hand eczema in the study period assessed by HECSI score.
Secondary Outcome Measures
Improvement in dyshidrotic eczema in the study period assessed by the patient (Visual Analog Scale).
Full Information
NCT ID
NCT00442091
First Posted
February 28, 2007
Last Updated
March 2, 2020
Sponsor
Odense University Hospital
1. Study Identification
Unique Protocol Identification Number
NCT00442091
Brief Title
Dandelion Juice in the Treatment of Dyshidrotic Hand Eczema
Official Title
Dandelion Juice in the Treatment of Dyshidrotic Hand Eczema
Study Type
Interventional
2. Study Status
Record Verification Date
March 2020
Overall Recruitment Status
Completed
Study Start Date
December 2010 (undefined)
Primary Completion Date
December 2019 (Actual)
Study Completion Date
December 2019 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Odense University Hospital
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
Dandelion juice has been used in herbal medicine for at least 1000 years. Vesicular hand eczema is a rare, but difficult to treat, type of hand eczema. One case report has shown that ingestion of dandelion juice could induce a beneficial effect on this type of eczema. The purpose of this study is to test whether this effect can be retrieved in other patients.
Detailed Description
Dandelion juice has been used in herbal medicine for at least 1000 years. One case report has shown a beneficial effect of this herbal remedy on dyshidrotic hand eczema, and the purpose of this pilot study is to test whether this effect can be retrieved in other patients.
The patients are recruited from our out-patient clinic. Only patients with negative patch tests to Compositae are offered treatment with dandelion juice for 20-30 days.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Vesicular Palmoplantar Eczema, Pompholyx
Keywords
Dandelion, herbal remedy, hand eczema, Compositae
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
4 (Actual)
8. Arms, Groups, and Interventions
Arm Title
10 ml of dandelion juice twice daily
Arm Type
Other
Intervention Type
Drug
Intervention Name(s)
dandelion juice
Intervention Description
10 ml bid for 20-30 days
Primary Outcome Measure Information:
Title
Improvement in dyshidrotic hand eczema in the study period assessed by HECSI score.
Time Frame
3-4 weeks
Secondary Outcome Measure Information:
Title
Improvement in dyshidrotic eczema in the study period assessed by the patient (Visual Analog Scale).
Time Frame
3-4 weeks
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Adult patients with dyshidrotic eczema for at least 1 year and negative patch test reactions to Compositae (tested within the last 3 years) and normal renal and hepatic blood tests.
Exclusion Criteria:
Treatment with systemic steroids or other immunosuppressive/-modulating drugs, including UV therapy, within the last 3 months.
Pregnancy, lactation.
Compositae contact allergy.
Liver or gall bladder disease.
Abnormal renal or hepatic blood tests.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Evy Paulsen, Dr.
Organizational Affiliation
Department of Dermatology, Odense University Hospital, DK-5000 Odense C
Official's Role
Principal Investigator
Facility Information:
Facility Name
Department of Dermatology, Odense University Hospital
City
Odense
ZIP/Postal Code
DK-5000
Country
Denmark
12. IPD Sharing Statement
Plan to Share IPD
No
Learn more about this trial
Dandelion Juice in the Treatment of Dyshidrotic Hand Eczema
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