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Comparing Rehabilitation Programs for Patellofemoral Pain Syndrome

Primary Purpose

Patellofemoral Pain Syndrome

Status
Completed
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Hip Progressive Resistive Exercise
Quad Progressive Resistive Exercises
Sponsored by
Timothy Uhl
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Patellofemoral Pain Syndrome focused on measuring Knee pain, Rehabilitation

Eligibility Criteria

15 Years - 35 Years (Child, Adult)FemaleAccepts Healthy Volunteers

Inclusion Criteria:

  • anterior or retropatellar knee pain reported during at least 2 of the following activities: ascending and descending stairs, hopping and running, squatting, kneeling, and prolonged sitting
  • insidious onset of symptoms not related to trauma
  • pain with compression of the patella
  • pain on palpation of the patellar facets

Exclusion Criteria:

  • symptoms present for less than one month
  • clinical evidence of other knee pathology
  • history of recent knee surgery within past one year
  • history of patellar dislocations or subluxations
  • current significant injury affecting other lower extremity joints

Sites / Locations

  • University of Kentucky

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Active Comparator

Arm Label

Hip Progressive Resistive Exercises

Quad Progressive Resistive Exercises

Arm Description

Exercises targeting hip musculature such as hip abduction and hip external rotation that was progressed by increased resistance following typical progressive resistive exercise approach.

Exercises targeting quadriceps musculature such as quadriceps isometric setting, terminal knee extensions, and straight leg raises that was progressed by increased resistance following typical progressive resistive exercise approach..

Outcomes

Primary Outcome Measures

Visual Analog Pain Scale (Describing Worst Pain Felt During the Past Week)
0 to 10 cm line with 0 representing no pain and 10 representing severe pain
Subjective Function by Lower Extremity Functional Scale Report Form
Visual Analog Pain Scale
Visual analog pain scale at end of intervention. 0 to 10 cm line with 0 representing no pain and 10 representing severe pain

Secondary Outcome Measures

Strength by Isometric Dynamometer
Neuromuscular Activity by Surface Electromyographical Amplitude During Stair Descent
Objective Function by Step-down Task for 30 Seconds
Hip Abduction Strength
Side lying Hip Abduction maximal muscular contraction with a hand held dynamometer

Full Information

First Posted
March 6, 2007
Last Updated
February 25, 2017
Sponsor
Timothy Uhl
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1. Study Identification

Unique Protocol Identification Number
NCT00445224
Brief Title
Comparing Rehabilitation Programs for Patellofemoral Pain Syndrome
Official Title
Comparison of Early Hip Strengthening to Early Quadriceps Strengthening in the Treatment of Females With Patellofemoral Pain
Study Type
Interventional

2. Study Status

Record Verification Date
February 2017
Overall Recruitment Status
Completed
Study Start Date
January 2008 (undefined)
Primary Completion Date
January 2010 (Actual)
Study Completion Date
January 2010 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor-Investigator
Name of the Sponsor
Timothy Uhl

4. Oversight

Data Monitoring Committee
No

5. Study Description

Brief Summary
Patellofemoral pain syndrome (PFPS) is a common knee disorder affecting physically active people. Despite the growing base of support for the early introduction of hip strengthening exercises into the rehabilitation of PFPS, there have been few randomized clinical trials comparing isolated hip to isolated quadriceps strengthening. The purpose of this study is to determine how different exercises affect pain, strength, muscle activity, and function in female subjects with patellofemoral pain. The researchers hypothesize that females diagnosed with PFPS who initially participate in a hip strengthening program will report a greater perceived level of function, greater strength, less pain, and improved neuromuscular activity than those who participate in a progressive quadriceps strengthening intervention.
Detailed Description
Methods: Thirty-three females with PFPS will perform either initial hip strengthening (hip group) or initial quadriceps strengthening (quad group) for 4 weeks, prior to 4 weeks of a similar program of functional weight-bearing exercises. Self-reported pain, function, and functional strength were measured. Isometric strength was assessed for hip abductors, external rotators, and knee extensors. A mixed-model analysis of variance will be used to determine group differences over time.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Patellofemoral Pain Syndrome
Keywords
Knee pain, Rehabilitation

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Crossover Assignment
Masking
Participant
Allocation
Randomized
Enrollment
33 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Hip Progressive Resistive Exercises
Arm Type
Experimental
Arm Description
Exercises targeting hip musculature such as hip abduction and hip external rotation that was progressed by increased resistance following typical progressive resistive exercise approach.
Arm Title
Quad Progressive Resistive Exercises
Arm Type
Active Comparator
Arm Description
Exercises targeting quadriceps musculature such as quadriceps isometric setting, terminal knee extensions, and straight leg raises that was progressed by increased resistance following typical progressive resistive exercise approach..
Intervention Type
Other
Intervention Name(s)
Hip Progressive Resistive Exercise
Intervention Description
Hip Progressive Resistance Exercise program will be carried out by subjects under supervision once a week and then performed at home 2 additional times at home without supervision. Exercises focus on strengthening hip abduction ad external rotation musculature.
Intervention Type
Other
Intervention Name(s)
Quad Progressive Resistive Exercises
Intervention Description
Quad Progressive Resistive Exercise program will be carried out by subjects under supervision once a week and then performed at home 2 additional times at home without supervision. Exercises focus on strengthening quadriceps musculature with straight leg raises and quadriceps isometrics.
Primary Outcome Measure Information:
Title
Visual Analog Pain Scale (Describing Worst Pain Felt During the Past Week)
Description
0 to 10 cm line with 0 representing no pain and 10 representing severe pain
Time Frame
weekly
Title
Subjective Function by Lower Extremity Functional Scale Report Form
Time Frame
Baseline, Mid-Intervention, and Post-Intervention
Title
Visual Analog Pain Scale
Description
Visual analog pain scale at end of intervention. 0 to 10 cm line with 0 representing no pain and 10 representing severe pain
Time Frame
8 week
Secondary Outcome Measure Information:
Title
Strength by Isometric Dynamometer
Time Frame
Baseline, Mid, and Post-Intervention
Title
Neuromuscular Activity by Surface Electromyographical Amplitude During Stair Descent
Time Frame
Baseline, Mid and Post-Intervention
Title
Objective Function by Step-down Task for 30 Seconds
Time Frame
Baseline, Mid, and Post-Intervention
Title
Hip Abduction Strength
Description
Side lying Hip Abduction maximal muscular contraction with a hand held dynamometer
Time Frame
8 week

10. Eligibility

Sex
Female
Minimum Age & Unit of Time
15 Years
Maximum Age & Unit of Time
35 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: anterior or retropatellar knee pain reported during at least 2 of the following activities: ascending and descending stairs, hopping and running, squatting, kneeling, and prolonged sitting insidious onset of symptoms not related to trauma pain with compression of the patella pain on palpation of the patellar facets Exclusion Criteria: symptoms present for less than one month clinical evidence of other knee pathology history of recent knee surgery within past one year history of patellar dislocations or subluxations current significant injury affecting other lower extremity joints
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Timothy Uhl, PhD, ATC, PT
Organizational Affiliation
University of Kentucky
Official's Role
Study Chair
Facility Information:
Facility Name
University of Kentucky
City
Lexington
State/Province
Kentucky
ZIP/Postal Code
40506
Country
United States

12. IPD Sharing Statement

Plan to Share IPD
Undecided
IPD Sharing Plan Description
willing to share strength and patient reported outcome data at pre, mid, and post testing time points.
Citations:
PubMed Identifier
21654093
Citation
Dolak KL, Silkman C, Medina McKeon J, Hosey RG, Lattermann C, Uhl TL. Hip strengthening prior to functional exercises reduces pain sooner than quadriceps strengthening in females with patellofemoral pain syndrome: a randomized clinical trial. J Orthop Sports Phys Ther. 2011 Aug;41(8):560-70. doi: 10.2519/jospt.2011.3499. Epub 2011 Jun 7. Erratum In: J Orthop Sports Phys Ther. 2011 Sep;41(9):700.
Results Reference
derived

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Comparing Rehabilitation Programs for Patellofemoral Pain Syndrome

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