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Improving Depression Treatment for Older Minority Adults

Primary Purpose

Depression

Status
Completed
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Problem Solving Therapy (PST)
Medication Management
Sponsored by
National Institute on Aging (NIA)
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Depression focused on measuring psychotherapy, behavior therapy, counseling, aging, medically underserved population

Eligibility Criteria

60 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • Patients of the LAC+USC Medical Center Geriatric Clinic
  • English- or Spanish-speaking
  • Positive for depression on the Geriatric Depression Scale
  • Current major depressive disorder or dysthymia
  • All adult family members, especially caregivers, and all regular clinic providers eligible for interviews

Exclusion Criteria:

  • History of bipolar disorder or psychosis
  • Significant cognitive impairment (score less than 24 on the Mini-Mental Status Examination, adjusted for age and education)
  • Acute suicidal ideation

Sites / Locations

  • LAC+USC Medical Center Geriatric Clinic

Arms of the Study

Arm 1

Arm Type

Experimental

Arm Label

1.

Arm Description

All participants

Outcomes

Primary Outcome Measures

Depression severity, depression treatment preferences, and barriers to care

Secondary Outcome Measures

Feasibility, acceptability, and effectiveness of intervention

Full Information

First Posted
December 7, 2007
Last Updated
February 24, 2009
Sponsor
National Institute on Aging (NIA)
Collaborators
University of California, Los Angeles
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1. Study Identification

Unique Protocol Identification Number
NCT00570427
Brief Title
Improving Depression Treatment for Older Minority Adults
Official Title
Improving Depression Treatment for Older Minority Adults
Study Type
Interventional

2. Study Status

Record Verification Date
February 2009
Overall Recruitment Status
Completed
Study Start Date
February 2007 (undefined)
Primary Completion Date
June 2008 (Actual)
Study Completion Date
June 2008 (Actual)

3. Sponsor/Collaborators

Name of the Sponsor
National Institute on Aging (NIA)
Collaborators
University of California, Los Angeles

4. Oversight

Data Monitoring Committee
Yes

5. Study Description

Brief Summary
The purpose of this study is to improve access to quality depression care for older, low-income, minority adults in public sector health care. The study will examine current depression care in a public sector geriatric clinic that serves mostly Spanish-speaking Latinos and pilot study assessments and treatments in order to lay the groundwork for a large study of quality improvement for depressed older minorities
Detailed Description
Depressive disorders affect 5-10% of older primary care patients, although rates may be higher among Latinos, especially among immigrants and those less acculturated. Late-life depression may be chronic and recurrent and results in significant morbidity and mortality. Despite a growing evidence base for the treatment of geriatric depression, only half of depressed older adults receive mental health care; fewer than 10% receive specialty services. Treatment rates are even lower for low-income, ethnic minorities who may be more ill and disabled, may lack adequate insurance and have different treatment preferences, and who frequently face barriers to accessing care. Recent quality improvement interventions for geriatric depression have targeted primary care, the location where older patients and ethnic minorities are most likely to receive mental health services. A recent multi-site, randomized trial of collaborative care for geriatric depression in primary care offered patients their choice of treatments, including antidepressant medication or 6-8 sessions of a structured psychotherapy. Although the intervention had few cultural accommodations, both processes and outcomes of care improved for depressed older minorities. However, because the study only included Latinos who were English-speaking and mostly high school graduates, these results may not generalize to a large proportion of ethnic minorities. This study first examines current rates of depression and patterns of depression treatment in a public-sector geriatric clinic that serves mostly Spanish-speaking Latinos. Then depressed patients are identified and their depression treatment preferences and barriers to care are assessed. Patients are enrolled in a 6-month patient-centered, evidence-based intervention, and they, family members, and clinic medical providers are interviewed at program end to assess the feasibility, acceptability, and possible effectiveness of the intervention.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Depression
Keywords
psychotherapy, behavior therapy, counseling, aging, medically underserved population

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
Non-Randomized
Enrollment
30 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
1.
Arm Type
Experimental
Arm Description
All participants
Intervention Type
Behavioral
Intervention Name(s)
Problem Solving Therapy (PST)
Intervention Description
Counseling
Intervention Type
Behavioral
Intervention Name(s)
Medication Management
Intervention Description
If a participant chooses to receive antidepressant medication while in the study, a depression care specialist works with the participant's usual primary care provider to initiate an appropriate prescription and to follow-up with side effects, adherence, efficacy, etc. on a monthly or biweekly basis.
Primary Outcome Measure Information:
Title
Depression severity, depression treatment preferences, and barriers to care
Time Frame
baseline and 6 months
Secondary Outcome Measure Information:
Title
Feasibility, acceptability, and effectiveness of intervention
Time Frame
6 months

10. Eligibility

Sex
All
Minimum Age & Unit of Time
60 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Patients of the LAC+USC Medical Center Geriatric Clinic English- or Spanish-speaking Positive for depression on the Geriatric Depression Scale Current major depressive disorder or dysthymia All adult family members, especially caregivers, and all regular clinic providers eligible for interviews Exclusion Criteria: History of bipolar disorder or psychosis Significant cognitive impairment (score less than 24 on the Mini-Mental Status Examination, adjusted for age and education) Acute suicidal ideation
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Isabel T. Lagomasino, MD MSHS
Organizational Affiliation
Department of Psychiatry, Keck School of Medicine, University of Southern California
Official's Role
Principal Investigator
Facility Information:
Facility Name
LAC+USC Medical Center Geriatric Clinic
City
Los Angeles
State/Province
California
ZIP/Postal Code
90033
Country
United States

12. IPD Sharing Statement

Citations:
PubMed Identifier
17484933
Citation
Dwight-Johnson M, Lagomasino IT. Addressing depression treatment preferences of ethnic minority patients. Gen Hosp Psychiatry. 2007 May-Jun;29(3):179-81. doi: 10.1016/j.genhosppsych.2007.02.001. No abstract available.
Results Reference
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PubMed Identifier
17325113
Citation
Vega WA, Karno M, Alegria M, Alvidrez J, Bernal G, Escamilla M, Escobar J, Guarnaccia P, Jenkins J, Kopelowicz A, Lagomasino IT, Lewis-Fernandez R, Marin H, Lopez S, Loue S. Research issues for improving treatment of U.S. Hispanics with persistent mental disorders. Psychiatr Serv. 2007 Mar;58(3):385-94. doi: 10.1176/ps.2007.58.3.385.
Results Reference
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PubMed Identifier
16339612
Citation
Lagomasino IT, Dwight-Johnson M, Miranda J, Zhang L, Liao D, Duan N, Wells KB. Disparities in depression treatment for Latinos and site of care. Psychiatr Serv. 2005 Dec;56(12):1517-23. doi: 10.1176/appi.ps.56.12.1517.
Results Reference
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Improving Depression Treatment for Older Minority Adults

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