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Application and Evaluation of Transference Focused Psychotherapy Modified for Adolescents (TFP-A)

Primary Purpose

Identity Pathology, Behavior Problems

Status
Unknown status
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Psychotherapy
Individual Psychotherapy
Sponsored by
Weill Medical College of Cornell University
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Identity Pathology focused on measuring Identity difussion, Adolescent psychotherapy, Transference Focused Psychotherapy for Adolescents, Identity, Identity crisis, Identity pathology

Eligibility Criteria

14 Years - 21 Years (Child, Adult)FemaleDoes not accept healthy volunteers

Inclusion Criteria:

  1. Female Adolescents, ages 14-21
  2. A score of five out of nine critical items on the Borderline Personality Disorder Dimension Interview Scale.
  3. Have interpersonal difficulties in school, family, and/or peer functioning.
  4. Live at home with family.
  5. Willingness to attend evaluation sessions and weekly, individual therapy.

Exclusion Criteria:

  1. The presence of psychosis, substance dependence, non-verbal learning disability, antisocial behavior, and/or primary diagnoses of eating disorder, bipolar disorder, and obsessive-compulsive disorder.
  2. The need for hospitalization for symptom management.
  3. Significant cognitive impairment (Full Scale IQ <85).
  4. The presence of a life-threatening medical illness.

Sites / Locations

  • New York-Presbyterian HospitalRecruiting

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Active Comparator

Arm Label

TFP-A

Control

Arm Description

Specific aspects of TFP-A involve the setting up of a treatment contract/collaboration between patient and therapist to deal with the likely threats both to the treatment and to the patient's well being that may occur in the course of the treatment. After the behavioral symptoms of identity pathology are contained through structure and limit setting, the psychological structure that is believed to be the core of identity pathology are analyzed. In particular, treatment would involve the family in setting up the contract parameters, provide a psychoeducational component to the family and patient, inclusion of school personnel as appropriate to reinforce contract parameters, place an emphasis on the technique of clarification to understand specific emotional states.

The Control Group is treatment as usual in the outpatient clinic. Treatment in this arm will be carried out by therapists in the Outpatient Department. Treatment will be determined by the therapist(s) and carried out according to their particular orientation and their assessment of patient's needs. It is expected based on clinic data that the majority of patients will be seen at least one time per week.

Outcomes

Primary Outcome Measures

Reduction in interpersonal difficulties with parents, teachers, and/or peers. Improved management of their feelings and moods. Reduction in other problems behaviors (i.e. substance use, self-injurious behaviors)

Secondary Outcome Measures

Full Information

First Posted
December 11, 2007
Last Updated
January 3, 2011
Sponsor
Weill Medical College of Cornell University
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1. Study Identification

Unique Protocol Identification Number
NCT00571571
Brief Title
Application and Evaluation of Transference Focused Psychotherapy Modified for Adolescents
Acronym
TFP-A
Official Title
Application and Evaluation of Transference Focused Psychotherapy Modified for Adolescents
Study Type
Interventional

2. Study Status

Record Verification Date
January 2011
Overall Recruitment Status
Unknown status
Study Start Date
October 2007 (undefined)
Primary Completion Date
December 2009 (Anticipated)
Study Completion Date
December 2009 (Anticipated)

3. Sponsor/Collaborators

Name of the Sponsor
Weill Medical College of Cornell University

4. Oversight

Data Monitoring Committee
No

5. Study Description

Brief Summary
Normal adolescence requires a successful resolution of identity crisis, which results in the development of satisfying relationships, success in school/work pursuits, and achievement of personal goals. Adolescents, who do not resolve this crisis, are at high risk for problems in those areas of functioning. Transference Focused Psychotherapy for Adolescents (TFP-A) is a treatment that specifically addresses these issues, permitting adolescents to develop satisfying friendships, more appropriate interactions with authority, and achieve realistic life goals. This study will evaluate the application of TFP-A, (a empirically validated treatment for adults with identity disturbance), to adolescents exhibiting the same behavioral and identity pathology. Subjects will be females; ages 14-21, with behaviors associated with identity problems, interpersonal difficulties with teachers, parents and/or peers, and live with their families. These adolescents will be randomly assigned to one of two treatment cells, TFP-A or Treatment as Usual (TAU). Subjects in TFP-A will receive weekly individual therapy for six months. The TAU group will receive standard individual therapy in the Outpatient Department. Both will receive medication as necessary. All subjects will participate in initial, weekly, and bi-monthly assessments during the six-month treatment period, and participate in a naturalistic follow-up study for an additional six months. Hypothesis: Adolescents with identity problems as seen in interpersonal, school, and/or family difficulties in the Transference Focused Psychotherapy for Adolescents (TFP-A) group will reduce these problem behaviors and improve management of their feelings and moods compared to adolescents with identity problems in the treatment as usual control group (TAU).

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Identity Pathology, Behavior Problems
Keywords
Identity difussion, Adolescent psychotherapy, Transference Focused Psychotherapy for Adolescents, Identity, Identity crisis, Identity pathology

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
20 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
TFP-A
Arm Type
Experimental
Arm Description
Specific aspects of TFP-A involve the setting up of a treatment contract/collaboration between patient and therapist to deal with the likely threats both to the treatment and to the patient's well being that may occur in the course of the treatment. After the behavioral symptoms of identity pathology are contained through structure and limit setting, the psychological structure that is believed to be the core of identity pathology are analyzed. In particular, treatment would involve the family in setting up the contract parameters, provide a psychoeducational component to the family and patient, inclusion of school personnel as appropriate to reinforce contract parameters, place an emphasis on the technique of clarification to understand specific emotional states.
Arm Title
Control
Arm Type
Active Comparator
Arm Description
The Control Group is treatment as usual in the outpatient clinic. Treatment in this arm will be carried out by therapists in the Outpatient Department. Treatment will be determined by the therapist(s) and carried out according to their particular orientation and their assessment of patient's needs. It is expected based on clinic data that the majority of patients will be seen at least one time per week.
Intervention Type
Behavioral
Intervention Name(s)
Psychotherapy
Other Intervention Name(s)
TFP-A, Transference Focused Psychotherapy for Adolescents
Intervention Description
Individual psychotherapy with parent collateral/psychoeducation as necessary.
Intervention Type
Behavioral
Intervention Name(s)
Individual Psychotherapy
Intervention Description
Individual psychotherapy and family interventions (as needed)
Primary Outcome Measure Information:
Title
Reduction in interpersonal difficulties with parents, teachers, and/or peers. Improved management of their feelings and moods. Reduction in other problems behaviors (i.e. substance use, self-injurious behaviors)
Time Frame
Subjects will be assessed at entry, 2 month, 4 months, 6 months, 8 months 10 months, and 12 months

10. Eligibility

Sex
Female
Minimum Age & Unit of Time
14 Years
Maximum Age & Unit of Time
21 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Female Adolescents, ages 14-21 A score of five out of nine critical items on the Borderline Personality Disorder Dimension Interview Scale. Have interpersonal difficulties in school, family, and/or peer functioning. Live at home with family. Willingness to attend evaluation sessions and weekly, individual therapy. Exclusion Criteria: The presence of psychosis, substance dependence, non-verbal learning disability, antisocial behavior, and/or primary diagnoses of eating disorder, bipolar disorder, and obsessive-compulsive disorder. The need for hospitalization for symptom management. Significant cognitive impairment (Full Scale IQ <85). The presence of a life-threatening medical illness.
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Anna E Odom, Ph.D.
Phone
914-997-5946
Email
ano9021@med.cornell.edu
First Name & Middle Initial & Last Name or Official Title & Degree
Pamela A Foelsch, Ph.D.
Phone
212-213-9879
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Anna E Odom, Ph.D.
Organizational Affiliation
Weill Medical College of Cornell University
Official's Role
Principal Investigator
Facility Information:
Facility Name
New York-Presbyterian Hospital
City
White Plains
State/Province
New York
ZIP/Postal Code
10605
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Maura L Lehr, LCSW
Phone
914-997-5866
Email
mll9001@nyp.org
First Name & Middle Initial & Last Name & Degree
Anna E Odom, Ph.D.

12. IPD Sharing Statement

Citations:
PubMed Identifier
11778390
Citation
Clarkin JF, Foelsch PA, Levy KN, Hull JW, Delaney JC, Kernberg OF. The development of a psychodynamic treatment for patients with borderline personality disorder: a preliminary study of behavioral change. J Pers Disord. 2001 Dec;15(6):487-95. doi: 10.1521/pedi.15.6.487.19190.
Results Reference
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PubMed Identifier
17541052
Citation
Clarkin JF, Levy KN, Lenzenweger MF, Kernberg OF. Evaluating three treatments for borderline personality disorder: a multiwave study. Am J Psychiatry. 2007 Jun;164(6):922-8. doi: 10.1176/ajp.2007.164.6.922.
Results Reference
background
PubMed Identifier
15061344
Citation
Clarkin JF, Levy KN, Lenzenweger MF, Kernberg OF. The Personality Disorders Institute/Borderline Personality Disorder Research Foundation randomized control trial for borderline personality disorder: rationale, methods, and patient characteristics. J Pers Disord. 2004 Feb;18(1):52-72. doi: 10.1521/pedi.18.1.52.32769.
Results Reference
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Application and Evaluation of Transference Focused Psychotherapy Modified for Adolescents

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