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Venous Thromboembolic Event (VTE) Prophylaxis in Medically Ill Patients (MAGELLAN)

Primary Purpose

Venous Thromboembolism

Status
Completed
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
Rivaroxaban (Xarelto, BAY59-7939)
Enoxaparin
Rivaroxaban placebo
Enoxaparin placebo
Sponsored by
Bayer
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional prevention trial for Venous Thromboembolism focused on measuring Acute medical illnesses with increased risk for VTE., Deep vein thrombosis (DVT), Pulmonary embolism (PE),, Venous Thromboembolic disease (VTE),, Medical illness

Eligibility Criteria

40 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • Male and female patients aged 40 years or more

  • Patients at risk of venous thromboembolic events being hospitalized for acute medical conditions as follows:

    • Heart failure, New York Heart Association (NYHA) class III or IV
    • Active cancer
    • Acute ischemic stroke
    • Acute infectious and inflammatory diseases, including acute rheumatic diseases
    • Acute respiratory insufficiency
    • Additional risk factor for VTE, including reduced mobility

Exclusion Criteria:

  • Conditions that contraindicate the use of antithrombotic therapy with the Low Molecular-Weight Heparin (LMWH) enoxaparin
  • Conditions that may increase the risk of bleeding, including intracranial hemorrhage
  • Required drugs or procedures which may interfere with the study treatment
  • Concomitant conditions or diseases which may increase the risk of study subjects or interfere with the study outcome
  • General conditions in which subjects are not suitable to participate in the study

Sites / Locations

  • Office of Dr. John Simmons, MD
  • Hospital de Agudos "Dr. Carlos Bocalandro"
  • Hospital Británico
  • Sanatorio Mitre
  • Hotel Dieu-Grace Hospital
  • CHUM - Hopital Notre-Dame
  • The 1st Affiliated Hosp of the 4th Military Med Uni
  • 1st Affiliated Hosp., Med College Xi'an Jiaotong Univ.
  • Beijing Friendship Hosp.
  • National Hospital Organization Ibaraki Higashi Hospital
  • Seoul National University Hospital
  • Seoul Metropolitan Boramae Hospital
  • Changi General Hospital

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Active Comparator

Arm Label

Rivaroxaban (Xarelto, BAY59-7939)

Enoxaparin

Arm Description

Participants received 10 mg oral rivaroxaban tablet once daily (OD) for 35 +/- 4 days, plus subcutaneous enoxaparin-matched placebo solution OD for 10 +/- 4 days

Participants received oral rivaroxaban-matched placebo tablet OD for 35 +/- 4 days, plus 40 mg subcutaneous enoxaparin solution OD for 10 +/- 4 days

Outcomes

Primary Outcome Measures

Percentage of Participants With Composite Endpoint of Venous Thromboembolism [VTE] (Any Deep Vein Thrombosis [DVT], Non Fatal Pulmonary Embolism [PE]) and VTE-related Death up to Day 35 + 6 Days
A composite endpoint of: asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and VTE-related death.
Percentage of Participants With Composite Endpoint of VTE (Any DVT, Non Fatal PE) and VTE-related Death up to Day 10 + 5 Days
A composite endpoint of: asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and VTE-related death.

Secondary Outcome Measures

Percentage of Participants With Composite Endpoint of VTE (Any DVT, Non Fatal PE) and All-cause Mortality up to Day 35 + 6 Days
A composite endpoint of: asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and death (VTE-related and not VTE-related).
Percentage of Participants With Composite Endpoint of VTE (Any DVT, Non Fatal PE) and VTE-related Death up to Day 10 + 5 Days Per mITT Population
A composite endpoint of: asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and VTE-related death.
Percentage of Participants With VTE Combined With All-cause Mortality up to Day 10 + 5 Days
A composite endpoint of: asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and death (VTE-related and not VTE-related).
Percentage of Participants With Symptomatic VTE, Including and Excluding VTE-related Death up to Days 10, 35, and 90
Symptomatic VTE (non-fatal PE and DVT in lower extremity), including and excluding VTE-related death (PE and PE cannot be excluded) up to Days 10, 35, and 90
Percentage of Participants With Net Clinical Benefit (Any DVT, Non-fatal PE, VTE-related Death, Plus Major and Clinically Relevant Non-major Bleeding Events) up to Day 35 + 6 Days
Net clinical benefit is a composite of the primary efficacy endpoint (asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and VTE-related death) plus major and clinically relevant non-major bleeding events.
Percentage of Participants With Net Clinical Benefit (Any DVT, Non-fatal PE, VTE-related Death, Plus Major and Clinically Relevant Non-major Bleeding Events) up to Day 10 + 5 Days
Net clinical benefit is a composite of the primary efficacy endpoint (asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and VTE-related death) plus major and clinically relevant non-major bleeding events
Percentage of Participants With Major Vascular Events up to Days 10, 35, and 90
Major vascular events included cardiovascular death, acute myocardial infarction (MI), or acute ischemic stroke. Participants may have had a vascular event in more than one category.
Percentage of Participants With Each Component of the Composite Endpoint of VTE (Any DVT, Non Fatal PE) and VTE-related Death up to Day 35 + 6 Days
The components of the composite endpoint include asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and VTE-related death.
Percentage of Participants With Each Component of the Composite Endpoint of VTE (Any DVT, Non Fatal PE) and VTE-related Death up to Day 10 + 5 Days
The components of the composite endpoint include asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and VTE-related death.
Percentage of Participants With All-cause Mortality up to Day 90 + 7 Days
All deaths, including VTE-related deaths, cardiovascular deaths, and other deaths.
Percentage of Participants With the Composite of Treatment Emergent Major Bleeding Events and Non-major Clinically Relevant Bleeding Events up to 2 Days After Last Intake of Any Study Medication (Day 35 + 6 Days)
Major bleeding events were defined as events leading to >=2 g/dL fall in hemoglobin; or transfusion of >= 2 units of packed RBCs (Red blood cells) or whole blood; or leading to death. Non-major bleeding events were defined as overt bleeding not meeting the criteria of major bleeding
Percentage of Participants With the Composite of Treatment Emergent Major Bleeding Events and Non-major Clinically Relevant Bleeding Events up to 2 Days After Last Application of a Study Medication Syringe (Day 10 + 5 Days)
Major bleeding events were defined as events leading to >=2 g/dL fall in hemoglobin or transfusion of >=2 units of packed RBCs or whole blood or leading to death. Non-major bleeding events were defined as overt bleeding not meeting the criteria of major bleeding.

Full Information

First Posted
December 11, 2007
Last Updated
August 3, 2016
Sponsor
Bayer
Collaborators
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
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1. Study Identification

Unique Protocol Identification Number
NCT00571649
Brief Title
Venous Thromboembolic Event (VTE) Prophylaxis in Medically Ill Patients
Acronym
MAGELLAN
Official Title
Multicenter, Randomized, Parallel-group Efficacy and Safety Study for the Prevention of Venous Thromboembolism in Hospitalized Medically Ill Patients Comparing Rivaroxaban With Enoxaparin. The MAGELLAN Study
Study Type
Interventional

2. Study Status

Record Verification Date
August 2016
Overall Recruitment Status
Completed
Study Start Date
December 2007 (undefined)
Primary Completion Date
August 2010 (Actual)
Study Completion Date
November 2010 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Bayer
Collaborators
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

4. Oversight

Data Monitoring Committee
Yes

5. Study Description

Brief Summary
This study will evaluate if extended therapy with oral rivaroxaban can prevent blood clots in the leg and lung that can occur with patients hospitalized for acute medical illness, and compare these results with those of the standard enoxaparin dose and duration regimen. The safety of rivaroxaban will also be studied.
Detailed Description
The treatment period was followed by a follow-up period starting the day after the last intake of study medication, regardless of the actual duration of study drug administration and ended on Day 90 (+ 7 days). Participants who did not complete the treatment period also entered the follow-up period. It was also possible that participants did not enter the follow-up period, e.g. due to withdrawal of consent or termination of study participation. Within the US 'Johnson & Johnson Pharmaceutical Research & Development, L.L.C.' is sponsor.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Venous Thromboembolism
Keywords
Acute medical illnesses with increased risk for VTE., Deep vein thrombosis (DVT), Pulmonary embolism (PE),, Venous Thromboembolic disease (VTE),, Medical illness

7. Study Design

Primary Purpose
Prevention
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
ParticipantCare ProviderInvestigatorOutcomes Assessor
Allocation
Randomized
Enrollment
8101 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Rivaroxaban (Xarelto, BAY59-7939)
Arm Type
Experimental
Arm Description
Participants received 10 mg oral rivaroxaban tablet once daily (OD) for 35 +/- 4 days, plus subcutaneous enoxaparin-matched placebo solution OD for 10 +/- 4 days
Arm Title
Enoxaparin
Arm Type
Active Comparator
Arm Description
Participants received oral rivaroxaban-matched placebo tablet OD for 35 +/- 4 days, plus 40 mg subcutaneous enoxaparin solution OD for 10 +/- 4 days
Intervention Type
Drug
Intervention Name(s)
Rivaroxaban (Xarelto, BAY59-7939)
Intervention Description
Oral rivaroxaban 10 mg once daily administered for 35 +/- 4 days
Intervention Type
Drug
Intervention Name(s)
Enoxaparin
Intervention Description
Subcutaneous enoxaparin 40 mg once daily (OD) administered for 10 +/- 4 days
Intervention Type
Drug
Intervention Name(s)
Rivaroxaban placebo
Intervention Description
Oral rivaroxaban-matched placebo tablet OD for 35 +/- 4 days
Intervention Type
Drug
Intervention Name(s)
Enoxaparin placebo
Intervention Description
Subcutaneous enoxaparin-matched placebo solution OD for 10 +/- 4 days
Primary Outcome Measure Information:
Title
Percentage of Participants With Composite Endpoint of Venous Thromboembolism [VTE] (Any Deep Vein Thrombosis [DVT], Non Fatal Pulmonary Embolism [PE]) and VTE-related Death up to Day 35 + 6 Days
Description
A composite endpoint of: asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and VTE-related death.
Time Frame
Up to Day 35 + 6 days
Title
Percentage of Participants With Composite Endpoint of VTE (Any DVT, Non Fatal PE) and VTE-related Death up to Day 10 + 5 Days
Description
A composite endpoint of: asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and VTE-related death.
Time Frame
Up to Day 10 + 5 days
Secondary Outcome Measure Information:
Title
Percentage of Participants With Composite Endpoint of VTE (Any DVT, Non Fatal PE) and All-cause Mortality up to Day 35 + 6 Days
Description
A composite endpoint of: asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and death (VTE-related and not VTE-related).
Time Frame
Up to Day 35 + 6 days
Title
Percentage of Participants With Composite Endpoint of VTE (Any DVT, Non Fatal PE) and VTE-related Death up to Day 10 + 5 Days Per mITT Population
Description
A composite endpoint of: asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and VTE-related death.
Time Frame
Up to Day 10 + 5 days
Title
Percentage of Participants With VTE Combined With All-cause Mortality up to Day 10 + 5 Days
Description
A composite endpoint of: asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and death (VTE-related and not VTE-related).
Time Frame
Up to Day 10 + 5 days
Title
Percentage of Participants With Symptomatic VTE, Including and Excluding VTE-related Death up to Days 10, 35, and 90
Description
Symptomatic VTE (non-fatal PE and DVT in lower extremity), including and excluding VTE-related death (PE and PE cannot be excluded) up to Days 10, 35, and 90
Time Frame
At Day 10 + 5 days, at Day 35 + 6 days, and at Day 90 + 7 days
Title
Percentage of Participants With Net Clinical Benefit (Any DVT, Non-fatal PE, VTE-related Death, Plus Major and Clinically Relevant Non-major Bleeding Events) up to Day 35 + 6 Days
Description
Net clinical benefit is a composite of the primary efficacy endpoint (asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and VTE-related death) plus major and clinically relevant non-major bleeding events.
Time Frame
Up to Day 35 + 6 days
Title
Percentage of Participants With Net Clinical Benefit (Any DVT, Non-fatal PE, VTE-related Death, Plus Major and Clinically Relevant Non-major Bleeding Events) up to Day 10 + 5 Days
Description
Net clinical benefit is a composite of the primary efficacy endpoint (asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and VTE-related death) plus major and clinically relevant non-major bleeding events
Time Frame
Up to Day 10 + 5 days
Title
Percentage of Participants With Major Vascular Events up to Days 10, 35, and 90
Description
Major vascular events included cardiovascular death, acute myocardial infarction (MI), or acute ischemic stroke. Participants may have had a vascular event in more than one category.
Time Frame
At Day 10 + 5 days, at Day 35 + 6 days, and at Day 90 + 7 days
Title
Percentage of Participants With Each Component of the Composite Endpoint of VTE (Any DVT, Non Fatal PE) and VTE-related Death up to Day 35 + 6 Days
Description
The components of the composite endpoint include asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and VTE-related death.
Time Frame
Up to Day 35 + 6 days
Title
Percentage of Participants With Each Component of the Composite Endpoint of VTE (Any DVT, Non Fatal PE) and VTE-related Death up to Day 10 + 5 Days
Description
The components of the composite endpoint include asymptomatic proximal DVT in lower extremity detected by mandatory bilateral lower extremity venous ultrasonography; symptomatic DVT in lower extremity, proximal or distal; symptomatic, non-fatal PE; and VTE-related death.
Time Frame
Up to Day 10 + 5 days
Title
Percentage of Participants With All-cause Mortality up to Day 90 + 7 Days
Description
All deaths, including VTE-related deaths, cardiovascular deaths, and other deaths.
Time Frame
Up to Day 90 + 7 days
Title
Percentage of Participants With the Composite of Treatment Emergent Major Bleeding Events and Non-major Clinically Relevant Bleeding Events up to 2 Days After Last Intake of Any Study Medication (Day 35 + 6 Days)
Description
Major bleeding events were defined as events leading to >=2 g/dL fall in hemoglobin; or transfusion of >= 2 units of packed RBCs (Red blood cells) or whole blood; or leading to death. Non-major bleeding events were defined as overt bleeding not meeting the criteria of major bleeding
Time Frame
Up to Day 35 + 6 days
Title
Percentage of Participants With the Composite of Treatment Emergent Major Bleeding Events and Non-major Clinically Relevant Bleeding Events up to 2 Days After Last Application of a Study Medication Syringe (Day 10 + 5 Days)
Description
Major bleeding events were defined as events leading to >=2 g/dL fall in hemoglobin or transfusion of >=2 units of packed RBCs or whole blood or leading to death. Non-major bleeding events were defined as overt bleeding not meeting the criteria of major bleeding.
Time Frame
Up to Day 10 + 5 days

10. Eligibility

Sex
All
Minimum Age & Unit of Time
40 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Male and female patients aged 40 years or more Patients at risk of venous thromboembolic events being hospitalized for acute medical conditions as follows: Heart failure, New York Heart Association (NYHA) class III or IV Active cancer Acute ischemic stroke Acute infectious and inflammatory diseases, including acute rheumatic diseases Acute respiratory insufficiency Additional risk factor for VTE, including reduced mobility Exclusion Criteria: Conditions that contraindicate the use of antithrombotic therapy with the Low Molecular-Weight Heparin (LMWH) enoxaparin Conditions that may increase the risk of bleeding, including intracranial hemorrhage Required drugs or procedures which may interfere with the study treatment Concomitant conditions or diseases which may increase the risk of study subjects or interfere with the study outcome General conditions in which subjects are not suitable to participate in the study
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Bayer Study Director
Organizational Affiliation
Bayer
Official's Role
Study Director
Facility Information:
City
Birmingham
State/Province
Alabama
ZIP/Postal Code
35209
Country
United States
City
Birmingham
State/Province
Alabama
ZIP/Postal Code
35235
Country
United States
City
Dothan
State/Province
Alabama
ZIP/Postal Code
36301
Country
United States
Facility Name
Office of Dr. John Simmons, MD
City
Geneva
State/Province
Alabama
ZIP/Postal Code
36340
Country
United States
City
Mobile
State/Province
Alabama
ZIP/Postal Code
36608
Country
United States
City
Montgomery
State/Province
Alabama
ZIP/Postal Code
36111
Country
United States
City
Tuscaloosa
State/Province
Alabama
ZIP/Postal Code
35401
Country
United States
City
Tuscaloosa
State/Province
Alabama
ZIP/Postal Code
35406
Country
United States
City
Little Rock
State/Province
Arkansas
ZIP/Postal Code
72205
Country
United States
City
Chula Vista
State/Province
California
ZIP/Postal Code
91911
Country
United States
City
Duarte
State/Province
California
ZIP/Postal Code
91010
Country
United States
City
Encinitas
State/Province
California
ZIP/Postal Code
92024
Country
United States
City
Fountain Valley
State/Province
California
ZIP/Postal Code
92708
Country
United States
City
Fullerton
State/Province
California
ZIP/Postal Code
92835
Country
United States
City
Glendale
State/Province
California
ZIP/Postal Code
91206
Country
United States
City
Oceanside
State/Province
California
ZIP/Postal Code
92056
Country
United States
City
Pasadena
State/Province
California
ZIP/Postal Code
91105
Country
United States
City
Redlands
State/Province
California
ZIP/Postal Code
92373
Country
United States
City
Sacramento
State/Province
California
ZIP/Postal Code
95817
Country
United States
City
San Diego
State/Province
California
ZIP/Postal Code
92120
Country
United States
City
Santa Barbara
State/Province
California
ZIP/Postal Code
93102
Country
United States
City
Torrance
State/Province
California
ZIP/Postal Code
90502-2004
Country
United States
City
Denver
State/Province
Colorado
ZIP/Postal Code
80204
Country
United States
City
Pueblo
State/Province
Colorado
ZIP/Postal Code
81003
Country
United States
City
Wheat Ridge
State/Province
Colorado
ZIP/Postal Code
80033-6017
Country
United States
City
Farmington
State/Province
Connecticut
ZIP/Postal Code
06030
Country
United States
City
Newark
State/Province
Delaware
ZIP/Postal Code
19718
Country
United States
City
Washington
State/Province
District of Columbia
ZIP/Postal Code
20037
Country
United States
City
Aventura
State/Province
Florida
ZIP/Postal Code
33180
Country
United States
City
Boyton Beach
State/Province
Florida
ZIP/Postal Code
33472
Country
United States
City
Clearwater
State/Province
Florida
ZIP/Postal Code
33756
Country
United States
City
Delray Beach
State/Province
Florida
ZIP/Postal Code
33445
Country
United States
City
Ft. Lauderdale
State/Province
Florida
ZIP/Postal Code
33334
Country
United States
City
Hollywood
State/Province
Florida
ZIP/Postal Code
33021
Country
United States
City
Jupiter
State/Province
Florida
ZIP/Postal Code
33458
Country
United States
City
Miami Springs
State/Province
Florida
ZIP/Postal Code
33166
Country
United States
City
Miami
State/Province
Florida
ZIP/Postal Code
33136
Country
United States
City
Miami
State/Province
Florida
ZIP/Postal Code
33173-3259
Country
United States
City
Pembroke Pines
State/Province
Florida
ZIP/Postal Code
33024
Country
United States
City
Port Charlotte
State/Province
Florida
ZIP/Postal Code
33952
Country
United States
City
Sarasota
State/Province
Florida
ZIP/Postal Code
34232
Country
United States
City
Vero Beach
State/Province
Florida
ZIP/Postal Code
32960
Country
United States
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30342
Country
United States
City
Decatur
State/Province
Georgia
ZIP/Postal Code
30030
Country
United States
City
Fort Gordon
State/Province
Georgia
ZIP/Postal Code
30905
Country
United States
City
Savannah
State/Province
Georgia
ZIP/Postal Code
31405
Country
United States
City
Idaho Falls
State/Province
Idaho
ZIP/Postal Code
83404
Country
United States
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60611
Country
United States
City
Springfield
State/Province
Illinois
ZIP/Postal Code
62702
Country
United States
City
Anderson
State/Province
Indiana
ZIP/Postal Code
46011
Country
United States
City
Noblesville
State/Province
Indiana
ZIP/Postal Code
46060
Country
United States
City
Des Moines
State/Province
Iowa
ZIP/Postal Code
50314-2611
Country
United States
City
Olathe
State/Province
Kansas
ZIP/Postal Code
66061
Country
United States
City
Lafayette
State/Province
Louisiana
ZIP/Postal Code
70503
Country
United States
City
New Orleans
State/Province
Louisiana
ZIP/Postal Code
70121
Country
United States
City
Shreveport
State/Province
Louisiana
ZIP/Postal Code
71130-4228
Country
United States
City
Biddeford
State/Province
Maine
ZIP/Postal Code
04005
Country
United States
City
Rockport
State/Province
Maine
ZIP/Postal Code
04856
Country
United States
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21215
Country
United States
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21237
Country
United States
City
Framingham
State/Province
Massachusetts
ZIP/Postal Code
01702
Country
United States
City
Ann Arbor
State/Province
Michigan
ZIP/Postal Code
48106
Country
United States
City
Detroit
State/Province
Michigan
ZIP/Postal Code
48201
Country
United States
City
Detroit
State/Province
Michigan
ZIP/Postal Code
48202
Country
United States
City
Grand Rapids
State/Province
Michigan
ZIP/Postal Code
49525
Country
United States
City
Lansing
State/Province
Michigan
ZIP/Postal Code
48910
Country
United States
City
Petoskey
State/Province
Michigan
ZIP/Postal Code
49770-2297
Country
United States
City
Pontiac
State/Province
Michigan
ZIP/Postal Code
48341
Country
United States
City
St. Clair Shores
State/Province
Michigan
ZIP/Postal Code
48081
Country
United States
City
Minneapolis
State/Province
Minnesota
ZIP/Postal Code
55417
Country
United States
City
Kansas City
State/Province
Missouri
ZIP/Postal Code
64128
Country
United States
City
St. Louis
State/Province
Missouri
ZIP/Postal Code
63110
Country
United States
City
St. Louis
State/Province
Missouri
ZIP/Postal Code
63141
Country
United States
City
Anaconda
State/Province
Montana
ZIP/Postal Code
59711-2718
Country
United States
City
Great Falls
State/Province
Montana
ZIP/Postal Code
59405
Country
United States
City
Omaha
State/Province
Nebraska
ZIP/Postal Code
68131
Country
United States
City
Hackensack
State/Province
New Jersey
ZIP/Postal Code
07601-1991
Country
United States
City
New Brunswick
State/Province
New Jersey
ZIP/Postal Code
08901
Country
United States
City
Somerville
State/Province
New Jersey
ZIP/Postal Code
08876-2598
Country
United States
City
Summit
State/Province
New Jersey
ZIP/Postal Code
07901
Country
United States
City
Teaneck
State/Province
New Jersey
ZIP/Postal Code
07666
Country
United States
City
Brooklyn
State/Province
New York
ZIP/Postal Code
11215
Country
United States
City
Buffalo
State/Province
New York
ZIP/Postal Code
14215-3021
Country
United States
City
Jamaica
State/Province
New York
ZIP/Postal Code
11418
Country
United States
City
New Hyde Park
State/Province
New York
ZIP/Postal Code
11040-1496
Country
United States
City
New York
State/Province
New York
ZIP/Postal Code
10011
Country
United States
City
New York
State/Province
New York
ZIP/Postal Code
10065
Country
United States
City
Stony Brook
State/Province
New York
ZIP/Postal Code
11794
Country
United States
City
Valhalla
State/Province
New York
ZIP/Postal Code
10595
Country
United States
City
Durham
State/Province
North Carolina
ZIP/Postal Code
27710
Country
United States
City
Elizabeth City
State/Province
North Carolina
ZIP/Postal Code
27909
Country
United States
City
Greensboro
State/Province
North Carolina
ZIP/Postal Code
27403
Country
United States
City
Fargo
State/Province
North Dakota
ZIP/Postal Code
58122
Country
United States
City
Canton
State/Province
Ohio
ZIP/Postal Code
44718
Country
United States
City
Columbus
State/Province
Ohio
ZIP/Postal Code
43215
Country
United States
City
Maumee
State/Province
Ohio
ZIP/Postal Code
43537-1899
Country
United States
City
Toledo
State/Province
Ohio
ZIP/Postal Code
43606
Country
United States
City
Bethlehem
State/Province
Pennsylvania
ZIP/Postal Code
18015
Country
United States
City
Camp Hill
State/Province
Pennsylvania
ZIP/Postal Code
17011
Country
United States
City
Danville
State/Province
Pennsylvania
ZIP/Postal Code
17822
Country
United States
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19107
Country
United States
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19124
Country
United States
City
Scranton
State/Province
Pennsylvania
ZIP/Postal Code
18510
Country
United States
City
Wilkes-Barre
State/Province
Pennsylvania
ZIP/Postal Code
18711-3752
Country
United States
City
Charleston
State/Province
South Carolina
ZIP/Postal Code
29425
Country
United States
City
Memphis
State/Province
Tennessee
ZIP/Postal Code
38104
Country
United States
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37232-2650
Country
United States
City
Corsicana
State/Province
Texas
ZIP/Postal Code
75110
Country
United States
City
Dallas
State/Province
Texas
ZIP/Postal Code
75216-7167
Country
United States
City
Edinburg
State/Province
Texas
ZIP/Postal Code
78539
Country
United States
City
Houston
State/Province
Texas
ZIP/Postal Code
77024
Country
United States
City
Houston
State/Province
Texas
ZIP/Postal Code
77030-4009
Country
United States
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
City
McAllen
State/Province
Texas
ZIP/Postal Code
78503
Country
United States
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78218
Country
United States
City
Ogden
State/Province
Utah
ZIP/Postal Code
84403
Country
United States
City
Richmond
State/Province
Virginia
ZIP/Postal Code
23249
Country
United States
City
Richmond
State/Province
Virginia
ZIP/Postal Code
23298
Country
United States
City
Everett
State/Province
Washington
ZIP/Postal Code
98201
Country
United States
City
Tacoma
State/Province
Washington
ZIP/Postal Code
98405
Country
United States
City
Clarksburg
State/Province
West Virginia
ZIP/Postal Code
26301
Country
United States
City
Avellaneda
State/Province
Buenos Aires
ZIP/Postal Code
B1870CID
Country
Argentina
City
San Miguel
State/Province
Buenos Aires
ZIP/Postal Code
1663
Country
Argentina
Facility Name
Hospital de Agudos "Dr. Carlos Bocalandro"
City
Tres de Febrero
State/Province
Buenos Aires
ZIP/Postal Code
1657
Country
Argentina
City
Buenos Aires
State/Province
Ciudad Auton. de Buenos Aires
ZIP/Postal Code
1221
Country
Argentina
Facility Name
Hospital Británico
City
Buenos Aires
State/Province
Ciudad Auton. de Buenos Aires
ZIP/Postal Code
1280
Country
Argentina
Facility Name
Sanatorio Mitre
City
Buenos Aires
State/Province
Ciudad Auton. de Buenos Aires
ZIP/Postal Code
C1039AAO
Country
Argentina
City
Buenos Aires
State/Province
Ciudad Auton. de Buenos Aires
ZIP/Postal Code
C1431FWO
Country
Argentina
City
Vicente López
ZIP/Postal Code
1638
Country
Argentina
City
Garran
State/Province
Australian Capital Territory
ZIP/Postal Code
2605
Country
Australia
City
Kogarah
State/Province
New South Wales
ZIP/Postal Code
2217
Country
Australia
City
Lismore
State/Province
New South Wales
ZIP/Postal Code
2480
Country
Australia
City
Sydney
State/Province
New South Wales
ZIP/Postal Code
2229
Country
Australia
City
Auchenflower
State/Province
Queensland
ZIP/Postal Code
4066
Country
Australia
City
Brisbane
State/Province
Queensland
ZIP/Postal Code
4066
Country
Australia
City
Brisbane
State/Province
Queensland
ZIP/Postal Code
4101
Country
Australia
City
Redcliffe
State/Province
Queensland
ZIP/Postal Code
4020
Country
Australia
City
Southport
State/Province
Queensland
ZIP/Postal Code
4215
Country
Australia
City
Woollongabba
State/Province
Queensland
ZIP/Postal Code
4102
Country
Australia
City
Adelaide
State/Province
South Australia
ZIP/Postal Code
5042
Country
Australia
City
Launceston
State/Province
Tasmania
ZIP/Postal Code
7250
Country
Australia
City
Box Hill
State/Province
Victoria
ZIP/Postal Code
3128
Country
Australia
City
Clayton
State/Province
Victoria
ZIP/Postal Code
3168
Country
Australia
City
Melbourne
State/Province
Victoria
ZIP/Postal Code
3135
Country
Australia
City
Melbourne
State/Province
Victoria
ZIP/Postal Code
3144
Country
Australia
City
Perth
State/Province
Western Australia
ZIP/Postal Code
6000
Country
Australia
City
Kittsee
State/Province
Burgenland
ZIP/Postal Code
2421
Country
Austria
City
Oberpullendorf
State/Province
Burgenland
ZIP/Postal Code
7350
Country
Austria
City
Wolfsberg
State/Province
Kärnten
ZIP/Postal Code
9400
Country
Austria
City
Linz
State/Province
Oberösterreich
ZIP/Postal Code
4020
Country
Austria
City
Gratwein
State/Province
Steiermark
ZIP/Postal Code
8113
Country
Austria
City
Graz
State/Province
Steiermark
ZIP/Postal Code
8036
Country
Austria
City
Hartberg
State/Province
Steiermark
ZIP/Postal Code
8230
Country
Austria
City
Leoben
State/Province
Steiermark
ZIP/Postal Code
8700
Country
Austria
City
Zams
State/Province
Tirol
ZIP/Postal Code
6511
Country
Austria
City
Innsbruck
ZIP/Postal Code
6020
Country
Austria
City
Linz
ZIP/Postal Code
4020
Country
Austria
City
Mürzzuschlag
ZIP/Postal Code
8680
Country
Austria
City
St. Pölten
ZIP/Postal Code
3100
Country
Austria
City
Wien
ZIP/Postal Code
1030
Country
Austria
City
Wien
ZIP/Postal Code
1100
Country
Austria
City
Wien
ZIP/Postal Code
1140
Country
Austria
City
Aalst
ZIP/Postal Code
9300
Country
Belgium
City
Brugge
ZIP/Postal Code
8000
Country
Belgium
City
Bruxelles - Brussel
ZIP/Postal Code
1000
Country
Belgium
City
Dendermonde
ZIP/Postal Code
9200
Country
Belgium
City
Hasselt
ZIP/Postal Code
3500
Country
Belgium
City
HUY
ZIP/Postal Code
4500
Country
Belgium
City
Ieper
ZIP/Postal Code
8900
Country
Belgium
City
Leuven
ZIP/Postal Code
3000
Country
Belgium
City
Malmedy
ZIP/Postal Code
4960
Country
Belgium
City
MOL
ZIP/Postal Code
2400
Country
Belgium
City
Montigny S/sambre
ZIP/Postal Code
6061
Country
Belgium
City
Mortsel
ZIP/Postal Code
2640
Country
Belgium
City
Roeselare
ZIP/Postal Code
8800
Country
Belgium
City
Sint-niklaas
ZIP/Postal Code
9100
Country
Belgium
City
Tubize
ZIP/Postal Code
1480
Country
Belgium
City
Turnhout
ZIP/Postal Code
2300
Country
Belgium
City
Curitiba
State/Province
Parana
ZIP/Postal Code
80050-350
Country
Brazil
City
Porto Alegre
State/Province
Rio Grande do Sul
ZIP/Postal Code
90610-000
Country
Brazil
City
Campinas
State/Province
Sao Paulo
ZIP/Postal Code
130839 970
Country
Brazil
City
Santo Andre
State/Province
Sao Paulo
ZIP/Postal Code
09190-610
Country
Brazil
City
São Paulo
State/Province
Sao Paulo
ZIP/Postal Code
01323-001
Country
Brazil
City
São Paulo
State/Province
Sao Paulo
ZIP/Postal Code
04039 002
Country
Brazil
City
Sao Paulo
ZIP/Postal Code
05403-900
Country
Brazil
City
Sao Paulo
ZIP/Postal Code
05443000
Country
Brazil
City
Pleven
ZIP/Postal Code
5800
Country
Bulgaria
City
Ruse
ZIP/Postal Code
7002
Country
Bulgaria
City
Sofia
ZIP/Postal Code
1233
Country
Bulgaria
City
Sofia
ZIP/Postal Code
1606
Country
Bulgaria
City
Stara Zagora
ZIP/Postal Code
6000
Country
Bulgaria
City
Varna
ZIP/Postal Code
9010
Country
Bulgaria
City
Veliko Tarnovo
ZIP/Postal Code
5000
Country
Bulgaria
City
Calgary
State/Province
Alberta
ZIP/Postal Code
T2N 2T9
Country
Canada
City
Edmonton
State/Province
Alberta
ZIP/Postal Code
T5H 3V9
Country
Canada
City
Edmonton
State/Province
Alberta
ZIP/Postal Code
T6G 2B7
Country
Canada
City
Edmonton
State/Province
Alberta
ZIP/Postal Code
T6L 5X8
Country
Canada
City
Vancouver
State/Province
British Columbia
ZIP/Postal Code
V5Z 1M9
Country
Canada
City
Saint John
State/Province
New Brunswick
ZIP/Postal Code
E2L 4L2
Country
Canada
City
Cobourg
State/Province
Ontario
ZIP/Postal Code
K9A 5W6
Country
Canada
City
Ottawa
State/Province
Ontario
ZIP/Postal Code
K1Y 4E9
Country
Canada
City
Scarborough
State/Province
Ontario
ZIP/Postal Code
M1P 2V5
Country
Canada
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M5T 2S8
Country
Canada
Facility Name
Hotel Dieu-Grace Hospital
City
Windsor
State/Province
Ontario
ZIP/Postal Code
N9A 1E1
Country
Canada
City
Greenfield Park
State/Province
Quebec
ZIP/Postal Code
J4V 2H1
Country
Canada
Facility Name
CHUM - Hopital Notre-Dame
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H2L 4M1
Country
Canada
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H2L 4M1
Country
Canada
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H2W 1T8
Country
Canada
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H3T 1M5
Country
Canada
City
Ste-Foy
State/Province
Quebec
ZIP/Postal Code
G1V 4G5
Country
Canada
City
Quebec
ZIP/Postal Code
G1J 1Z4
Country
Canada
City
Quebec
ZIP/Postal Code
G1V 4G5
Country
Canada
City
Santiago
ZIP/Postal Code
760 0448
Country
Chile
City
Santiago
Country
Chile
City
Viña del Mar
Country
Chile
City
Guangzhou
State/Province
Guangdong
ZIP/Postal Code
510120
Country
China
City
Guangzhou
State/Province
Guangdong
ZIP/Postal Code
510405
Country
China
City
Guangzhou
State/Province
Guangdong
Country
China
City
Changsha
State/Province
Hunan
ZIP/Postal Code
410013
Country
China
City
Nanjing
State/Province
Jiangsu
ZIP/Postal Code
210008
Country
China
City
Nanjing
State/Province
Jiangsu
Country
China
City
Changchun
State/Province
Jilin
Country
China
City
Dalian
State/Province
Liaoning
ZIP/Postal Code
116027
Country
China
City
Shenyang
State/Province
Liaoning
ZIP/Postal Code
110001
Country
China
City
Shenyang
State/Province
Liaoning
ZIP/Postal Code
110004
Country
China
City
Shenyang
State/Province
Liaoning
ZIP/Postal Code
110015
Country
China
Facility Name
The 1st Affiliated Hosp of the 4th Military Med Uni
City
Xi'an
State/Province
Shaanxi
ZIP/Postal Code
710032
Country
China
Facility Name
1st Affiliated Hosp., Med College Xi'an Jiaotong Univ.
City
Xi'an
State/Province
Shaanxi
ZIP/Postal Code
710061
Country
China
City
Chengdu
State/Province
Sichuan
ZIP/Postal Code
610041
Country
China
City
Beijing
ZIP/Postal Code
100005
Country
China
City
Beijing
ZIP/Postal Code
100020
Country
China
City
Beijing
ZIP/Postal Code
100029
Country
China
City
Beijing
ZIP/Postal Code
100034
Country
China
City
Beijing
ZIP/Postal Code
100037
Country
China
City
Beijing
ZIP/Postal Code
100044
Country
China
Facility Name
Beijing Friendship Hosp.
City
Beijing
ZIP/Postal Code
100050
Country
China
City
Beijing
ZIP/Postal Code
100050
Country
China
City
Beijing
ZIP/Postal Code
100053
Country
China
City
Beijing
ZIP/Postal Code
100088
Country
China
City
Beijing
ZIP/Postal Code
100853
Country
China
City
Chongqing
ZIP/Postal Code
400038
Country
China
City
Chongqing
ZIP/Postal Code
400042
Country
China
City
Shanghai
ZIP/Postal Code
200003
Country
China
City
Shanghai
ZIP/Postal Code
200025
Country
China
City
Shanghai
ZIP/Postal Code
200127
Country
China
City
Shanghai
ZIP/Postal Code
200233
Country
China
City
Shanghai
Country
China
City
Medellín
State/Province
Antioquia
Country
Colombia
City
Bogotá
State/Province
Distrito Capital de Bogotá
Country
Colombia
City
Cali
State/Province
Valle del Cauca
Country
Colombia
City
Bogota
Country
Colombia
City
Bogotá
Country
Colombia
City
Cali
Country
Colombia
City
Medellín
Country
Colombia
City
Osijek
ZIP/Postal Code
310 00
Country
Croatia
City
Rijeka
ZIP/Postal Code
51000
Country
Croatia
City
Zadar
ZIP/Postal Code
23000
Country
Croatia
City
Zagreb
ZIP/Postal Code
10000
Country
Croatia
City
Zagreb
ZIP/Postal Code
1000
Country
Croatia
City
Brno
ZIP/Postal Code
656 91
Country
Czech Republic
City
Kutna Hora
ZIP/Postal Code
284 30
Country
Czech Republic
City
Nove Mesto na Morave
ZIP/Postal Code
592 31
Country
Czech Republic
City
Olomouc
ZIP/Postal Code
775 20
Country
Czech Republic
City
Plzen
ZIP/Postal Code
305 99
Country
Czech Republic
City
Praha 2
ZIP/Postal Code
128 08
Country
Czech Republic
City
Praha 2
ZIP/Postal Code
128 21
Country
Czech Republic
City
Praha 2
ZIP/Postal Code
12808
Country
Czech Republic
City
Ricany
ZIP/Postal Code
251 49
Country
Czech Republic
City
Znojmo
ZIP/Postal Code
669 02
Country
Czech Republic
City
Esbjerg
ZIP/Postal Code
6700
Country
Denmark
City
Frederiksberg C
ZIP/Postal Code
2000
Country
Denmark
City
Kolding
ZIP/Postal Code
6000
Country
Denmark
City
København NV
ZIP/Postal Code
2400
Country
Denmark
City
København S
ZIP/Postal Code
2300
Country
Denmark
City
Roskilde
ZIP/Postal Code
4000
Country
Denmark
City
Tallinn
ZIP/Postal Code
10138
Country
Estonia
City
Tallinn
ZIP/Postal Code
13419
Country
Estonia
City
Tallinn
ZIP/Postal Code
EE-10617
Country
Estonia
City
Tartu
ZIP/Postal Code
EE-51014
Country
Estonia
City
Helsinki
ZIP/Postal Code
00290
Country
Finland
City
Hämeenlinna
ZIP/Postal Code
13530
Country
Finland
City
Jyväskylä
ZIP/Postal Code
40620
Country
Finland
City
Lahti
ZIP/Postal Code
15850
Country
Finland
City
Lappeenranta
ZIP/Postal Code
53130
Country
Finland
City
Raisio
ZIP/Postal Code
21200
Country
Finland
City
Turku
ZIP/Postal Code
20520
Country
Finland
City
Turku
ZIP/Postal Code
20700
Country
Finland
City
Arras
ZIP/Postal Code
62000
Country
France
City
Besancon
ZIP/Postal Code
25000
Country
France
City
Brest Cedex
ZIP/Postal Code
29609
Country
France
City
Castelnau Le Lez
ZIP/Postal Code
34170
Country
France
City
Clermont Ferrand
ZIP/Postal Code
63000
Country
France
City
Colombes Cedex
ZIP/Postal Code
92701
Country
France
City
Dijon
ZIP/Postal Code
21000
Country
France
City
Lille
ZIP/Postal Code
59037
Country
France
City
Lille
ZIP/Postal Code
59307
Country
France
City
Limoges
ZIP/Postal Code
87042
Country
France
City
Lomme
ZIP/Postal Code
59160
Country
France
City
Lyon
ZIP/Postal Code
69003
Country
France
City
Montpellier Cedex
ZIP/Postal Code
34295
Country
France
City
Nice
ZIP/Postal Code
06280
Country
France
City
Nimes
ZIP/Postal Code
30029
Country
France
City
Paris
ZIP/Postal Code
75004
Country
France
City
Paris
ZIP/Postal Code
75010
Country
France
City
Paris
ZIP/Postal Code
75475
Country
France
City
Paris
ZIP/Postal Code
75877
Country
France
City
Pierre Benite
ZIP/Postal Code
69495
Country
France
City
Reims
ZIP/Postal Code
51092
Country
France
City
Roubaix
ZIP/Postal Code
59100
Country
France
City
Saint Herblain Cedex
ZIP/Postal Code
44805
Country
France
City
Saint-etienne
ZIP/Postal Code
42000
Country
France
City
Strasbourg Cedex
ZIP/Postal Code
67091
Country
France
City
Toulouse
ZIP/Postal Code
31403
Country
France
City
TOURCOING cedex
ZIP/Postal Code
59208
Country
France
City
Vandoeuvre Les Nancy
ZIP/Postal Code
54511
Country
France
City
Bad Mergentheim
State/Province
Baden-Württemberg
ZIP/Postal Code
97980
Country
Germany
City
Esslingen
State/Province
Baden-Württemberg
ZIP/Postal Code
73730
Country
Germany
City
Heidelberg
State/Province
Baden-Württemberg
ZIP/Postal Code
69120
Country
Germany
City
Karlsbad
State/Province
Baden-Württemberg
ZIP/Postal Code
76307
Country
Germany
City
Weiden
State/Province
Bayern
ZIP/Postal Code
92637
Country
Germany
City
Beeskow
State/Province
Brandenburg
ZIP/Postal Code
15848
Country
Germany
City
Frankfurt/Oder
State/Province
Brandenburg
ZIP/Postal Code
15236
Country
Germany
City
Dortmund
State/Province
Nordrhein-Westfalen
ZIP/Postal Code
44137
Country
Germany
City
Jülich
State/Province
Nordrhein-Westfalen
ZIP/Postal Code
52428
Country
Germany
City
Köln
State/Province
Nordrhein-Westfalen
ZIP/Postal Code
50935
Country
Germany
City
Köln
State/Province
Nordrhein-Westfalen
ZIP/Postal Code
51067
Country
Germany
City
Köln
State/Province
Nordrhein-Westfalen
ZIP/Postal Code
51109
Country
Germany
City
Leverkusen
State/Province
Nordrhein-Westfalen
ZIP/Postal Code
51375
Country
Germany
City
Mönchengladbach
State/Province
Nordrhein-Westfalen
ZIP/Postal Code
41063
Country
Germany
City
Neuss
State/Province
Nordrhein-Westfalen
ZIP/Postal Code
41464
Country
Germany
City
Oberhausen
State/Province
Nordrhein-Westfalen
ZIP/Postal Code
46045
Country
Germany
City
Paderborn
State/Province
Nordrhein-Westfalen
ZIP/Postal Code
33098
Country
Germany
City
Soest
State/Province
Nordrhein-Westfalen
ZIP/Postal Code
59494
Country
Germany
City
Stolberg
State/Province
Nordrhein-Westfalen
ZIP/Postal Code
52222
Country
Germany
City
Troisdorf
State/Province
Nordrhein-Westfalen
ZIP/Postal Code
53844
Country
Germany
City
Viersen
State/Province
Nordrhein-Westfalen
ZIP/Postal Code
41749
Country
Germany
City
Wuppertal
State/Province
Nordrhein-Westfalen
ZIP/Postal Code
42109
Country
Germany
City
Mainz
State/Province
Rheinland-Pfalz
ZIP/Postal Code
55131
Country
Germany
City
Neuwied
State/Province
Rheinland-Pfalz
ZIP/Postal Code
56564
Country
Germany
City
Halle
State/Province
Sachsen-Anhalt
ZIP/Postal Code
06112
Country
Germany
City
Dresden
State/Province
Sachsen
ZIP/Postal Code
01067
Country
Germany
City
Dresden
State/Province
Sachsen
ZIP/Postal Code
01307
Country
Germany
City
Leipzig
State/Province
Sachsen
ZIP/Postal Code
04289
Country
Germany
City
Pirna
State/Province
Sachsen
ZIP/Postal Code
01796
Country
Germany
City
Berlin
ZIP/Postal Code
10787
Country
Germany
City
Bremen
ZIP/Postal Code
28177
Country
Germany
City
Elefsina
State/Province
Attica
ZIP/Postal Code
19018
Country
Greece
City
Kifisia / Athens
State/Province
Attica
ZIP/Postal Code
14561
Country
Greece
City
Abelokipi - Athens
ZIP/Postal Code
115 26
Country
Greece
City
Athens
ZIP/Postal Code
106 76
Country
Greece
City
Athens
ZIP/Postal Code
115 26
Country
Greece
City
Athens
ZIP/Postal Code
156 69
Country
Greece
City
Nea Ionia
ZIP/Postal Code
14233
Country
Greece
City
Piraeus
ZIP/Postal Code
18536
Country
Greece
City
Rio / Patras
ZIP/Postal Code
265 04
Country
Greece
City
Shatin
State/Province
N.t.
Country
Hong Kong
City
Shatin
Country
Hong Kong
City
Baja
ZIP/Postal Code
6500
Country
Hungary
City
Balassagyarmat
ZIP/Postal Code
2660
Country
Hungary
City
Budapest
ZIP/Postal Code
1076
Country
Hungary
City
Budapest
ZIP/Postal Code
1134
Country
Hungary
City
Budapest
ZIP/Postal Code
1145
Country
Hungary
City
Debrecen
ZIP/Postal Code
4012
Country
Hungary
City
Gyor
ZIP/Postal Code
9024
Country
Hungary
City
Hodmezovasarhely
ZIP/Postal Code
6800
Country
Hungary
City
Kecskemet
ZIP/Postal Code
6000
Country
Hungary
City
Szekesfehervar
ZIP/Postal Code
8000
Country
Hungary
City
Tatabanya
ZIP/Postal Code
2800
Country
Hungary
City
Zalaegerszeg-Pozva
ZIP/Postal Code
H-8900
Country
Hungary
City
Ahmedabad
State/Province
Gujar?t
ZIP/Postal Code
380 054
Country
India
City
Bangalore
State/Province
Karn?taka
ZIP/Postal Code
560052
Country
India
City
Bangalore
State/Province
Karn?taka
ZIP/Postal Code
560099
Country
India
City
Calicut
State/Province
Kerala
ZIP/Postal Code
673 004
Country
India
City
Thiruvananthapuram
State/Province
Kerala
ZIP/Postal Code
695002
Country
India
City
Pune
State/Province
Maharashtra
ZIP/Postal Code
411001
Country
India
City
Pune
State/Province
Maharashtra
ZIP/Postal Code
411011
Country
India
City
Ludhiana
State/Province
Punjab
ZIP/Postal Code
141001
Country
India
City
Chennai
State/Province
Tamil N?du
ZIP/Postal Code
600081
Country
India
City
Coimbatore
State/Province
Tamil N?du
ZIP/Postal Code
641 004
Country
India
City
Kolkata
State/Province
West Bengal
ZIP/Postal Code
700 099
Country
India
City
Hyderabad
ZIP/Postal Code
500034
Country
India
City
Hyderabad
ZIP/Postal Code
500082
Country
India
City
Hyderabad
ZIP/Postal Code
600 038
Country
India
City
Mumbai
ZIP/Postal Code
400022
Country
India
City
Noida
Country
India
City
Jakarta
ZIP/Postal Code
10430
Country
Indonesia
City
Jakarta
ZIP/Postal Code
11420
Country
Indonesia
City
Surabaya
ZIP/Postal Code
60286
Country
Indonesia
City
Afula
ZIP/Postal Code
1834111
Country
Israel
City
Ashkelon
ZIP/Postal Code
7830604
Country
Israel
City
Haifa
ZIP/Postal Code
31048
Country
Israel
City
Haifa
ZIP/Postal Code
3109601
Country
Israel
City
Holon
ZIP/Postal Code
58100
Country
Israel
City
Kfar Saba
ZIP/Postal Code
4428164
Country
Israel
City
Rehovot
ZIP/Postal Code
7610001
Country
Israel
City
Tel Aviv
ZIP/Postal Code
64239
Country
Israel
City
Zefat
ZIP/Postal Code
1311001
Country
Israel
City
Acquaviva delle Fonti
State/Province
Bari
ZIP/Postal Code
70021
Country
Italy
City
Napoli
State/Province
Campania
ZIP/Postal Code
80123
Country
Italy
City
Modena
State/Province
Emilia-Romagna
ZIP/Postal Code
41100
Country
Italy
City
Parma
State/Province
Emilia-Romagna
ZIP/Postal Code
43100
Country
Italy
City
Piacenza
State/Province
Emilia-Romagna
ZIP/Postal Code
29121
Country
Italy
City
Reggio Emilia
State/Province
Emilia-Romagna
ZIP/Postal Code
42123
Country
Italy
City
Roma
State/Province
Lazio
ZIP/Postal Code
00161
Country
Italy
City
Roma
State/Province
Lazio
ZIP/Postal Code
00168
Country
Italy
City
Genova
State/Province
Liguria
ZIP/Postal Code
16128
Country
Italy
City
Milano
State/Province
Lombardia
ZIP/Postal Code
20089
Country
Italy
City
Milano
State/Province
Lombardia
ZIP/Postal Code
20133
Country
Italy
City
Milano
State/Province
Lombardia
ZIP/Postal Code
20162
Country
Italy
City
Varese
State/Province
Lombardia
ZIP/Postal Code
21100
Country
Italy
City
Campobasso
State/Province
Molise
ZIP/Postal Code
86100
Country
Italy
City
Fidenza
State/Province
Parma
ZIP/Postal Code
43036
Country
Italy
City
Catania
State/Province
Sicilia
ZIP/Postal Code
95124
Country
Italy
City
Palermo
State/Province
Sicilia
ZIP/Postal Code
90127
Country
Italy
City
Terni
State/Province
Trentino-Alto Adige
ZIP/Postal Code
05019
Country
Italy
City
Perugia
State/Province
Umbria
ZIP/Postal Code
06024
Country
Italy
City
Perugia
State/Province
Umbria
ZIP/Postal Code
06156
Country
Italy
City
Domodossola
State/Province
Verbano-Cusio-Ossola
ZIP/Postal Code
28845
Country
Italy
City
Bergamo
ZIP/Postal Code
24128
Country
Italy
City
Latina
ZIP/Postal Code
04100
Country
Italy
City
Reggio Calabria
ZIP/Postal Code
89124
Country
Italy
City
Vicenza
ZIP/Postal Code
36100
Country
Italy
City
Ichinomiya
State/Province
Aichi
ZIP/Postal Code
491-8551
Country
Japan
City
Kasugai
State/Province
Aichi
ZIP/Postal Code
487-0013
Country
Japan
City
Obu
State/Province
Aichi
ZIP/Postal Code
474-8511
Country
Japan
City
Matsuyama
State/Province
Ehime
ZIP/Postal Code
790-0024
Country
Japan
City
Toon
State/Province
Ehime
ZIP/Postal Code
791-0281
Country
Japan
City
Chikushino
State/Province
Fukuoka
ZIP/Postal Code
818-8516
Country
Japan
City
Takasaki
State/Province
Gunma
ZIP/Postal Code
370-0829
Country
Japan
City
Kure
State/Province
Hiroshima
ZIP/Postal Code
737-0023
Country
Japan
City
Hakodate
State/Province
Hokkaido
ZIP/Postal Code
040-8611
Country
Japan
City
Sapporo
State/Province
Hokkaido
ZIP/Postal Code
065-0033
Country
Japan
City
Amagasaki
State/Province
Hyogo
ZIP/Postal Code
660-8511
Country
Japan
City
Kanazawa
State/Province
Ishikawa
ZIP/Postal Code
920-8650
Country
Japan
City
Hanamaki
State/Province
Iwate
ZIP/Postal Code
025-0075
Country
Japan
City
Ebina
State/Province
Kanagawa
ZIP/Postal Code
243-0433
Country
Japan
City
Kamakura
State/Province
Kanagawa
ZIP/Postal Code
247-8533
Country
Japan
City
Yokohama
State/Province
Kanagawa
ZIP/Postal Code
236-0051
Country
Japan
City
Nangoku
State/Province
Kochi
ZIP/Postal Code
783-8509
Country
Japan
City
Matsusaka
State/Province
Mie
ZIP/Postal Code
515-8544
Country
Japan
City
Tsu
State/Province
Mie
ZIP/Postal Code
514-1101
Country
Japan
City
Tsu
State/Province
Mie
ZIP/Postal Code
514-8507
Country
Japan
City
Kashiwazaki
State/Province
Niigata
ZIP/Postal Code
945-8585
Country
Japan
City
Tomigusuku
State/Province
Okinawa
ZIP/Postal Code
901-0243
Country
Japan
City
Urasoe
State/Province
Okinawa
ZIP/Postal Code
901-2132
Country
Japan
City
Daito
State/Province
Osaka
ZIP/Postal Code
574-0074
Country
Japan
City
Yao
State/Province
Osaka
ZIP/Postal Code
581-0011
Country
Japan
City
Kusatsu
State/Province
Shiga
ZIP/Postal Code
525-8585
Country
Japan
City
Hamamatsu
State/Province
Shizuoka
ZIP/Postal Code
432-8580
Country
Japan
City
Meguro-ku
State/Province
Tokyo
ZIP/Postal Code
152-8902
Country
Japan
City
Shinjuku-ku
State/Province
Tokyo
ZIP/Postal Code
162-8655
Country
Japan
City
Shimonoseki
State/Province
Yamaguchi
ZIP/Postal Code
750-0061
Country
Japan
City
Fukui
ZIP/Postal Code
910-8561
Country
Japan
Facility Name
National Hospital Organization Ibaraki Higashi Hospital
City
Ibaraki
ZIP/Postal Code
319-1113
Country
Japan
City
Kumamoto
ZIP/Postal Code
860-0008
Country
Japan
City
Kyoto
ZIP/Postal Code
606-8507
Country
Japan
City
Gyeongi-do
State/Province
Korea
ZIP/Postal Code
463-707
Country
Korea, Republic of
Facility Name
Seoul National University Hospital
City
Seoul
State/Province
Seoul Teugbyeolsi
ZIP/Postal Code
110-744
Country
Korea, Republic of
Facility Name
Seoul Metropolitan Boramae Hospital
City
Seoul
State/Province
Seoul Teugbyeolsi
ZIP/Postal Code
156-707
Country
Korea, Republic of
City
Gyeonggi-do
ZIP/Postal Code
463-712
Country
Korea, Republic of
City
Jeollanam-do
ZIP/Postal Code
519-763
Country
Korea, Republic of
City
Seoul
ZIP/Postal Code
135-710
Country
Korea, Republic of
City
Seoul
ZIP/Postal Code
138736
Country
Korea, Republic of
City
Daugavpils
ZIP/Postal Code
LV-5417
Country
Latvia
City
Liepaja
ZIP/Postal Code
3402
Country
Latvia
City
Riga
ZIP/Postal Code
1002
Country
Latvia
City
Riga
ZIP/Postal Code
1005
Country
Latvia
City
Riga
ZIP/Postal Code
LV-1001
Country
Latvia
City
Riga
ZIP/Postal Code
LV-1038
Country
Latvia
City
Valmiera
ZIP/Postal Code
LV-4201
Country
Latvia
City
Ventspils
ZIP/Postal Code
LV-3601
Country
Latvia
City
Kaunas
ZIP/Postal Code
LT-3000
Country
Lithuania
City
Kaunas
ZIP/Postal Code
LT-3002
Country
Lithuania
City
Kaunas
ZIP/Postal Code
LT-3026
Country
Lithuania
City
Klaipeda
ZIP/Postal Code
LT-5800
Country
Lithuania
City
Klaipeda
ZIP/Postal Code
LT-92231
Country
Lithuania
City
Siauliai
ZIP/Postal Code
76231
Country
Lithuania
City
Utena
ZIP/Postal Code
LT-28142
Country
Lithuania
City
Vilnius
ZIP/Postal Code
04130
Country
Lithuania
City
Vilnius
ZIP/Postal Code
10207
Country
Lithuania
City
Vilnius
ZIP/Postal Code
LT-2001
Country
Lithuania
City
Kirchberg
ZIP/Postal Code
2540
Country
Luxembourg
City
Luxembourg
ZIP/Postal Code
1210
Country
Luxembourg
City
Niederkorn
ZIP/Postal Code
4602
Country
Luxembourg
City
Kuala Lumpur
ZIP/Postal Code
59100
Country
Malaysia
City
Negeri Sembilan,
ZIP/Postal Code
70300
Country
Malaysia
City
Sarawak
ZIP/Postal Code
93400
Country
Malaysia
City
Tuxtla Gutiérrez
State/Province
Chiapas
ZIP/Postal Code
29000
Country
Mexico
City
Torreón
State/Province
Coahuila
ZIP/Postal Code
27250
Country
Mexico
City
Mexico D. F.
State/Province
Distrito Federal
ZIP/Postal Code
06760
Country
Mexico
City
Mexico D.F.
State/Province
Distrito Federal
ZIP/Postal Code
11340
Country
Mexico
City
Mexico D.F.
State/Province
Distrito Federal
ZIP/Postal Code
15900
Country
Mexico
City
México, D.F.
State/Province
Distrito Federal
ZIP/Postal Code
06729
Country
Mexico
City
México, D.F.
State/Province
Distrito Federal
ZIP/Postal Code
07760
Country
Mexico
City
México, D.F
State/Province
Distrito Federal
ZIP/Postal Code
07460
Country
Mexico
City
Guadalajara
State/Province
Jalisco
ZIP/Postal Code
44280
Country
Mexico
City
Morelia
State/Province
Michoacán
ZIP/Postal Code
58270
Country
Mexico
City
Metepec
State/Province
México
ZIP/Postal Code
52140
Country
Mexico
City
Monterrey
State/Province
Nuevo Leon
ZIP/Postal Code
66480
Country
Mexico
City
Hermosillo
State/Province
Sonora
ZIP/Postal Code
83000
Country
Mexico
City
Mérida
State/Province
Yucatán
ZIP/Postal Code
97001
Country
Mexico
City
Aguascalientes
ZIP/Postal Code
20234
Country
Mexico
City
Chihuahua
ZIP/Postal Code
31350
Country
Mexico
City
Puebla
ZIP/Postal Code
72410
Country
Mexico
City
Zacatecas
ZIP/Postal Code
98000
Country
Mexico
City
Amersfoort
ZIP/Postal Code
3816 CP
Country
Netherlands
City
Amsterdam
ZIP/Postal Code
1061 AE
Country
Netherlands
City
Enschede
ZIP/Postal Code
7511 JX
Country
Netherlands
City
Heerlen
ZIP/Postal Code
6401 CX
Country
Netherlands
City
Maastricht
ZIP/Postal Code
6229 HX
Country
Netherlands
City
Nieuwegein
ZIP/Postal Code
3435 CM
Country
Netherlands
City
Rotterdam
ZIP/Postal Code
3083 AN
Country
Netherlands
City
Sittard
ZIP/Postal Code
6131 BK
Country
Netherlands
City
Utrecht
ZIP/Postal Code
3582 KE
Country
Netherlands
City
Auckland
ZIP/Postal Code
0622
Country
New Zealand
City
Auckland
ZIP/Postal Code
1023
Country
New Zealand
City
Auckland
ZIP/Postal Code
2024
Country
New Zealand
City
Christchurch
ZIP/Postal Code
8011
Country
New Zealand
City
Fredrikstad
ZIP/Postal Code
1603
Country
Norway
City
Gjøvik
ZIP/Postal Code
2819
Country
Norway
City
Hamar
ZIP/Postal Code
2326
Country
Norway
City
Oslo
ZIP/Postal Code
0319
Country
Norway
City
Oslo
ZIP/Postal Code
0407
Country
Norway
City
Karachi
ZIP/Postal Code
74800
Country
Pakistan
City
Karachi
ZIP/Postal Code
75500
Country
Pakistan
City
Lahore
Country
Pakistan
City
Callao
ZIP/Postal Code
CALLAO 2
Country
Peru
City
Lima Cercado
ZIP/Postal Code
LIMA 1
Country
Peru
City
Lima
ZIP/Postal Code
01
Country
Peru
City
Lima
ZIP/Postal Code
31
Country
Peru
City
Lima
ZIP/Postal Code
LIMA 11
Country
Peru
City
Lima
ZIP/Postal Code
LIMA 1
Country
Peru
City
Bialystok
ZIP/Postal Code
15-276
Country
Poland
City
Bydgoszcz
ZIP/Postal Code
85-681
Country
Poland
City
Krakow
ZIP/Postal Code
31-066
Country
Poland
City
Krakow
ZIP/Postal Code
31-121
Country
Poland
City
Lublin
ZIP/Postal Code
20-178
Country
Poland
City
Olsztyn
ZIP/Postal Code
10-228
Country
Poland
City
Piotrkow Trybunalski
ZIP/Postal Code
97-300
Country
Poland
City
Siedlce
ZIP/Postal Code
08-110
Country
Poland
City
Starogard Gdanski
ZIP/Postal Code
83-200
Country
Poland
City
Szczecin
ZIP/Postal Code
70-965
Country
Poland
City
Tarnów
ZIP/Postal Code
33-100
Country
Poland
City
Warszawa
ZIP/Postal Code
03-401
Country
Poland
City
Warszawa
ZIP/Postal Code
04-141
Country
Poland
City
Warszawa
ZIP/Postal Code
04-749
Country
Poland
City
Wloclawek
ZIP/Postal Code
87-800
Country
Poland
City
S. Martinho do Bispo
State/Province
Coimbra
ZIP/Postal Code
3041-856
Country
Portugal
City
Amadora
ZIP/Postal Code
2720-276
Country
Portugal
City
Cascais
ZIP/Postal Code
2750-349
Country
Portugal
City
Coimbra
ZIP/Postal Code
3000-075
Country
Portugal
City
Lisboa
ZIP/Postal Code
1150-199
Country
Portugal
City
Lisboa
ZIP/Postal Code
1349-019
Country
Portugal
City
Lisboa
ZIP/Postal Code
1649-035
Country
Portugal
City
Lisboa
ZIP/Postal Code
1849- 017
Country
Portugal
City
Matosinhos
ZIP/Postal Code
4454-509
Country
Portugal
City
Porto
ZIP/Postal Code
4099-001
Country
Portugal
City
Porto
ZIP/Postal Code
4200-319
Country
Portugal
City
Santarém
ZIP/Postal Code
2005
Country
Portugal
City
Viana do Castelo
ZIP/Postal Code
4901-585
Country
Portugal
City
Bucharest
ZIP/Postal Code
014461
Country
Romania
City
Bucharest
ZIP/Postal Code
022328
Country
Romania
City
Bucharest
ZIP/Postal Code
041915
Country
Romania
City
Constanta
ZIP/Postal Code
900591
Country
Romania
City
Suceava
ZIP/Postal Code
720237
Country
Romania
City
Moscow
ZIP/Postal Code
103030
Country
Russian Federation
City
Moscow
ZIP/Postal Code
115093
Country
Russian Federation
City
Moscow
ZIP/Postal Code
115516
Country
Russian Federation
City
Moscow
ZIP/Postal Code
117292
Country
Russian Federation
City
Moscow
ZIP/Postal Code
119048
Country
Russian Federation
City
Moscow
ZIP/Postal Code
119435
Country
Russian Federation
City
Moscow
ZIP/Postal Code
125101
Country
Russian Federation
City
Moscow
ZIP/Postal Code
125367
Country
Russian Federation
City
Nizhny Novgorod
ZIP/Postal Code
603001
Country
Russian Federation
City
Nizhny Novgorod
ZIP/Postal Code
603035
Country
Russian Federation
City
Yaroslavl
ZIP/Postal Code
150003
Country
Russian Federation
City
Yaroslavl
ZIP/Postal Code
150030
Country
Russian Federation
City
Singapore
ZIP/Postal Code
119074
Country
Singapore
City
Singapore
ZIP/Postal Code
168752
Country
Singapore
City
Singapore
ZIP/Postal Code
169608
Country
Singapore
City
Singapore
ZIP/Postal Code
308433
Country
Singapore
Facility Name
Changi General Hospital
City
Singapore
ZIP/Postal Code
529889
Country
Singapore
City
Bratislava
ZIP/Postal Code
813 69
Country
Slovakia
City
Bratislava
ZIP/Postal Code
826 06
Country
Slovakia
City
Lucenec
ZIP/Postal Code
984 39
Country
Slovakia
City
Martin
ZIP/Postal Code
036 59
Country
Slovakia
City
Zilina
ZIP/Postal Code
012 07
Country
Slovakia
City
Golnik
ZIP/Postal Code
4204
Country
Slovenia
City
Ljubljana
ZIP/Postal Code
1000
Country
Slovenia
City
Novo mesto
ZIP/Postal Code
8000
Country
Slovenia
City
Bloemfontein
State/Province
Freestate
ZIP/Postal Code
9301
Country
South Africa
City
Johannesburg
State/Province
Gauteng
ZIP/Postal Code
2057
Country
South Africa
City
Johannesburg
State/Province
Gauteng
ZIP/Postal Code
2132
Country
South Africa
City
Johannesburg
State/Province
Gauteng
ZIP/Postal Code
2196
Country
South Africa
City
Kempton Park
State/Province
Gauteng
ZIP/Postal Code
1610
Country
South Africa
City
Pretoria
State/Province
Gauteng
ZIP/Postal Code
0084
Country
South Africa
City
Pretoria
State/Province
Gauteng
ZIP/Postal Code
0157
Country
South Africa
City
Pretoria
State/Province
Gauteng
ZIP/Postal Code
0181
Country
South Africa
City
Roodepoort
State/Province
Gauteng
ZIP/Postal Code
1724
Country
South Africa
City
Goodwood
State/Province
Western Cape
ZIP/Postal Code
7460
Country
South Africa
City
Somerset West
State/Province
Western Cape
ZIP/Postal Code
7130
Country
South Africa
City
Stellenbosch
State/Province
Western Cape
ZIP/Postal Code
7505
Country
South Africa
City
Worcester
State/Province
Western Cape
ZIP/Postal Code
6850
Country
South Africa
City
Sandton, Gauteng
ZIP/Postal Code
2196
Country
South Africa
City
Badalona
State/Province
Barcelona
ZIP/Postal Code
08916
Country
Spain
City
Sabadell
State/Province
Barcelona
ZIP/Postal Code
08208
Country
Spain
City
Cabra
State/Province
Córdoba
ZIP/Postal Code
14940
Country
Spain
City
Olot
State/Province
Girona
ZIP/Postal Code
17800
Country
Spain
City
Cartagena
State/Province
Murcia
ZIP/Postal Code
30202
Country
Spain
City
Vélez
State/Province
Málaga
ZIP/Postal Code
29700
Country
Spain
City
Vigo
State/Province
Pontevedra
ZIP/Postal Code
36214
Country
Spain
City
Barcelona
ZIP/Postal Code
08023
Country
Spain
City
Barcelona
ZIP/Postal Code
08036
Country
Spain
City
Cuenca
ZIP/Postal Code
16002
Country
Spain
City
Córdoba
ZIP/Postal Code
14004
Country
Spain
City
Girona
ZIP/Postal Code
17007
Country
Spain
City
Zaragoza
ZIP/Postal Code
50009
Country
Spain
City
Borås
ZIP/Postal Code
501 82
Country
Sweden
City
Hässleholm
ZIP/Postal Code
281 25
Country
Sweden
City
Karlshamn
ZIP/Postal Code
374 80
Country
Sweden
City
Kristianstad
ZIP/Postal Code
29185
Country
Sweden
City
Lund
ZIP/Postal Code
221 85
Country
Sweden
City
Malmö
ZIP/Postal Code
205 02
Country
Sweden
City
Skövde
ZIP/Postal Code
541 85
Country
Sweden
City
Stockholm
ZIP/Postal Code
171 76
Country
Sweden
City
Stockholm
ZIP/Postal Code
182 88
Country
Sweden
City
Sundsvall
ZIP/Postal Code
851 86
Country
Sweden
City
Umeå
ZIP/Postal Code
90185
Country
Sweden
City
Visby
ZIP/Postal Code
62184
Country
Sweden
City
Bruderholz
State/Province
Basel-Landschaft
ZIP/Postal Code
4101
Country
Switzerland
City
Basel
State/Province
Basel-Stadt
ZIP/Postal Code
4031
Country
Switzerland
City
Liestal
State/Province
Basel-Stadt
ZIP/Postal Code
4410
Country
Switzerland
City
Langenthal
State/Province
Bern
ZIP/Postal Code
4901
Country
Switzerland
City
Baden
ZIP/Postal Code
5404
Country
Switzerland
City
Bern
ZIP/Postal Code
3010
Country
Switzerland
City
Genève
ZIP/Postal Code
1211
Country
Switzerland
City
Luzern
ZIP/Postal Code
6000
Country
Switzerland
City
Zürich
ZIP/Postal Code
8091
Country
Switzerland
City
Kaohsiung
ZIP/Postal Code
833
Country
Taiwan
City
Tainan
ZIP/Postal Code
710
Country
Taiwan
City
Taipei
ZIP/Postal Code
10016
Country
Taiwan
City
Taipei
ZIP/Postal Code
114
Country
Taiwan
City
Taipei
Country
Taiwan
City
Bangkok
ZIP/Postal Code
10400
Country
Thailand
City
Bangkok
ZIP/Postal Code
10700
Country
Thailand
City
Chiangmai
ZIP/Postal Code
50200
Country
Thailand
City
Istanbul
ZIP/Postal Code
34098
Country
Turkey
City
Istanbul
ZIP/Postal Code
34304
Country
Turkey
City
Izmir
ZIP/Postal Code
35100
Country
Turkey
City
Izmir
ZIP/Postal Code
35340
Country
Turkey
City
Donetsk
ZIP/Postal Code
83003
Country
Ukraine
City
Donetsk
ZIP/Postal Code
83045
Country
Ukraine
City
Ivano-Frankivsk
ZIP/Postal Code
76000
Country
Ukraine
City
Kharkiv
ZIP/Postal Code
61037
Country
Ukraine
City
Kharkiv
ZIP/Postal Code
61070
Country
Ukraine
City
Kharkiv
ZIP/Postal Code
61178
Country
Ukraine
City
Kiev
ZIP/Postal Code
02 091
Country
Ukraine
City
Kiev
ZIP/Postal Code
03680
Country
Ukraine
City
Kiev
ZIP/Postal Code
04112
Country
Ukraine
City
Kyiv
ZIP/Postal Code
01105
Country
Ukraine
City
Lviv
ZIP/Postal Code
790 34
Country
Ukraine
City
Odessa
ZIP/Postal Code
65009
Country
Ukraine
City
Odessa
ZIP/Postal Code
65025
Country
Ukraine
City
Simferopol
ZIP/Postal Code
95 026
Country
Ukraine
City
Simferopol
ZIP/Postal Code
95023
Country
Ukraine
City
Middlesborough
State/Province
Cleveland
ZIP/Postal Code
TS4 3BW
Country
United Kingdom
City
Dumfries
State/Province
Dumfries and Galloway
ZIP/Postal Code
DG1 4EP
Country
United Kingdom
City
Liverpool
State/Province
Merseyside
ZIP/Postal Code
L9 7JU
Country
United Kingdom
City
Sheffield
State/Province
South Yorkshire
ZIP/Postal Code
S10 2JF
Country
United Kingdom
City
Glasgow
State/Province
Stratchclyde
ZIP/Postal Code
G11 6NT
Country
United Kingdom
City
Newcastle Upon Tyne
State/Province
Tyne and Wear
ZIP/Postal Code
NE1 4LP
Country
United Kingdom
City
Leeds
State/Province
West Yorkshire
ZIP/Postal Code
LS9 7TF
Country
United Kingdom
City
London
ZIP/Postal Code
N18 1QX
Country
United Kingdom
City
London
ZIP/Postal Code
SE5 9RS
Country
United Kingdom
City
London
ZIP/Postal Code
W1T 4EU
Country
United Kingdom
City
Nottingham
ZIP/Postal Code
NG7 2UH
Country
United Kingdom

12. IPD Sharing Statement

Citations:
PubMed Identifier
21359646
Citation
Cohen AT, Spiro TE, Buller HR, Haskell L, Hu D, Hull R, Mebazaa A, Merli G, Schellong S, Spyropoulos A, Tapson V. Extended-duration rivaroxaban thromboprophylaxis in acutely ill medical patients: MAGELLAN study protocol. J Thromb Thrombolysis. 2011 May;31(4):407-16. doi: 10.1007/s11239-011-0549-x.
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Citation
Cohen AT, Spiro TE, Buller HR, Haskell L, Hu D, Hull R, Mebazaa A, Merli G, Schellong S, Spyropoulos AC, Tapson V; MAGELLAN Investigators. Rivaroxaban for thromboprophylaxis in acutely ill medical patients. N Engl J Med. 2013 Feb 7;368(6):513-23. doi: 10.1056/NEJMoa1111096.
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Citation
Sharma A, Chatterjee S, Lichstein E, Mukherjee D. Extended thromboprophylaxis for medically ill patients with decreased mobility: does it improve outcomes? J Thromb Haemost. 2012 Oct;10(10):2053-60. doi: 10.1111/j.1538-7836.2012.04874.x.
Results Reference
result
PubMed Identifier
24970782
Citation
Mebazaa A, Spiro TE, Buller HR, Haskell L, Hu D, Hull R, Merli G, Schellong SW, Spyropoulos AC, Tapson VF, De Sanctis Y, Cohen AT. Predicting the risk of venous thromboembolism in patients hospitalized with heart failure. Circulation. 2014 Jul 29;130(5):410-8. doi: 10.1161/CIRCULATIONAHA.113.003126. Epub 2014 Jun 26.
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Citation
Cohen AT, Spiro TE, Spyropoulos AC, Desanctis YH, Homering M, Buller HR, Haskell L, Hu D, Hull R, Mebazaa A, Merli G, Schellong S, Tapson VF, Burton P; MAGELLAN Study Group. D-dimer as a predictor of venous thromboembolism in acutely ill, hospitalized patients: a subanalysis of the randomized controlled MAGELLAN trial. J Thromb Haemost. 2014 Apr;12(4):479-87. doi: 10.1111/jth.12515.
Results Reference
result
PubMed Identifier
35389229
Citation
Spyropoulos AC, Raskob GE, Cohen AT, Ageno W, Weitz JI, Spiro TE, Lu W, Lipardi C, Albers GW, Elliott CG, Halperin JL, Hiatt WR, Maynard G, Steg PG, Sugarmann C, Barnathan ES. Association of Bleeding Severity With Mortality in Extended Thromboprophylaxis of Medically Ill Patients in the MAGELLAN and MARINER Trials. Circulation. 2022 May 10;145(19):1471-1479. doi: 10.1161/CIRCULATIONAHA.121.057847. Epub 2022 Apr 7.
Results Reference
derived
PubMed Identifier
34755519
Citation
Raskob GE, Spyropoulos AC, Spiro TE, Lu W, Yuan Z, Levitan B, Suh E, Barnathan ES. Benefit-Risk of Rivaroxaban for Extended Thromboprophylaxis After Hospitalization for Medical Illness: Pooled Analysis From MAGELLAN and MARINER. J Am Heart Assoc. 2021 Nov 16;10(22):e021579. doi: 10.1161/JAHA.121.021579. Epub 2021 Nov 10.
Results Reference
derived
PubMed Identifier
33586478
Citation
Raskob GE, Spyropoulos AC, Cohen AT, Weitz JI, Ageno W, De Sanctis Y, Lu W, Xu J, Albanese J, Sugarmann C, Weber T, Lipardi C, Spiro TE, Barnathan ES. Association Between Asymptomatic Proximal Deep Vein Thrombosis and Mortality in Acutely Ill Medical Patients. J Am Heart Assoc. 2021 Feb;10(5):e019459. doi: 10.1161/JAHA.120.019459. Epub 2021 Feb 15.
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PubMed Identifier
32657973
Citation
Jamil A, Jamil U, Singh K, Khan F, Chi G. Extended Thromboprophylaxis With Betrixaban or Rivaroxaban for Acutely Ill Hospitalized Medical Patients: Meta-Analysis of Prespecified Subgroups. Crit Pathw Cardiol. 2021 Mar 1;20(1):16-24. doi: 10.1097/HPC.0000000000000232.
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PubMed Identifier
31975354
Citation
Weitz JI, Raskob GE, Spyropoulos AC, Spiro TE, De Sanctis Y, Xu J, Lu W, Suh E, Argenti D, Yang H, Albanese J, Lipardi C, Barnathan ES. Thromboprophylaxis with Rivaroxaban in Acutely Ill Medical Patients with Renal Impairment: Insights from the MAGELLAN and MARINER Trials. Thromb Haemost. 2020 Mar;120(3):515-524. doi: 10.1055/s-0039-1701009. Epub 2020 Jan 23.
Results Reference
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PubMed Identifier
28762617
Citation
Chi G, Goldhaber SZ, Kittelson JM, Turpie AGG, Hernandez AF, Hull RD, Gold A, Curnutte JT, Cohen AT, Harrington RA, Gibson CM. Effect of extended-duration thromboprophylaxis on venous thromboembolism and major bleeding among acutely ill hospitalized medical patients: a bivariate analysis. J Thromb Haemost. 2017 Oct;15(10):1913-1922. doi: 10.1111/jth.13783. Epub 2017 Sep 4.
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28617144
Citation
Marszalek J, Mehrsefat S, Chi G. The risk of stroke among acutely ill hospitalized medical patients: lessons from recent trials on extended-duration thromboprophylaxis. Expert Rev Hematol. 2017 Aug;10(8):679-684. doi: 10.1080/17474086.2017.1343662. Epub 2017 Jun 21.
Results Reference
derived
Links:
URL
http://www.clinicaltrialsregister.eu
Description
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Venous Thromboembolic Event (VTE) Prophylaxis in Medically Ill Patients

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