The Effect of Exercise on Individuals With Parkinson's Disease
Parkinson's Disease
About this trial
This is an interventional treatment trial for Parkinson's Disease focused on measuring Parkinson's disease, exercise
Eligibility Criteria
Inclusion Criteria:
- a diagnosis of PD
- Up to the age of 67
- on at least 1 DA drug, may be on several PD medications
- able to walk for six minutes (may take rest breaks)
- able to come off their PD medication for testing (12 hour overnight withdrawal of antiparkinsonian medications)
- able to stay on stable PD medications for at least 6 months
- live within a 30 mile radius of Chicago
- Hoehn and Yahr Score: II - III while in the "Off" PD medication state
Exclusion Criteria:
- history of any other neurological disorder as determined by medical history and neurological exam
- history of a known injury, disease, or other disorder that might interfere with motor function in the proposed experiments
- a score less than 23 on the Mini-Mental State Examination
- currently involved in an active, ongoing formal exercise program deep brain stimulation surgery
- known cardiac problem or significant hypertension
- depression that may interfere with regular exercise
- hallucinations or being treated for hallucinations
Sites / Locations
- Physical Therapy Department at the University of Illinois at Chicago
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Progressive resistance training
Modified Fitness Counts
Subjects will perform between 60 and 90 minutes of progressive resistance training two times a week for two years at a local gym. These sessions will be supervised by a personal trainer two times a week for the first six months of training and then once a week for the remaining 18 months of training.
Subjects will perform between 60 and 90 minutes of modified Fitness Counts two times a week for two years at a local gym. These sessions will be supervised by a personal trainer two times a week for the first six months of training and then once a week for the remaining 18 months of training.