Patterns of Failure
Patients with any new evidence of cancer after achieving a complete response are considered to have recurrent disease. Biopsy verification will be obtained if at all possible and salvage surgery is recommended if possible. Disease recurrence will be characterized as either local, regional(nodal) or distant recurrence. Patients may have more than one kind of recurrence.
Overall Survival
Number of patients still alive from 2 years from start of study
Number of Patients With a Clinical Response-complete Disappearance of Detectable Tumor
Twelve weeks after completing chemoradiotherapy, a formal evaluation for response will be made, to include a careful evaluation by the head and neck surgeon, medical and radiation oncologists, and, as appropriate, a radiologic and an endoscopic examination. Patients will be considered to have achieved either a clinical complete response (i.e. complete disappearance of all clinically and radiologically detectable tumor) or to have clinical persistent disease.
Number of Patients With a Pathological(Final)Complete Response
A Pathological, or final response will be assigned to subjects after any salvage surgery is performed for clinical persistent disease, and after planned neck dissection in those achieving a clinical complete response. If no surgery is performed after chemoradiotherapy, the clinical and pathological (final) response will be the same. Patient will be coded as having either a pathologic complete response, or as having pathologic persistent disease. A pathologic complete response will be defined as the total disappearance of all clinically and radiologically detectable tumor.
Disease Recurrence
Number of patients with any new evidence of cancer after achieving a complete response (at 12 weeks after completing chemoradiotherapy) are considered to have recurrent disease.
Number of Patients That Required a Feeding Tube
Number of Patients That Required a Feeding Tube
Number of Patients That Required a Feeding Tube
Number of Patients That Required a Feeding Tube
Nausea Level
Quality of life questionnaire asking "I have nausea".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4).
N (number of patients analyzed) is based on number of patients who completed the question.
Nausea Level
Quality of life questionnaire asking "I have nausea".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Nausea Level
Quality of life questionnaire asking "I have nausea".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Nausea Level
Quality of life questionnaire asking "I have nausea".
Dry Mouth
Quality of life questionnaire asking "My mouth is dry".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Dry Mouth
Quality of life questionnaire asking "My mouth is dry".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Dry Mouth
Quality of life questionnaire asking "My mouth is dry".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Dry Mouth
Quality of life questionnaire asking "My mouth is dry".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Pain
Quality of life questionnaire asking "I have pain in my mouth, throat or neck".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Pain
Quality of life questionnaire asking "I have pain in my mouth, throat or neck".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Pain
Quality of life questionnaire asking "I have pain in my mouth, throat or neck".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Pain
Quality of life questionnaire asking "I have pain in my mouth, throat or neck".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Quality of Life
Quality of life questionnaire asking "I am content with the quality of my life right now".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Quality of Life
Quality of life questionnaire asking "I am content with the quality of my life right now".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Quality of Life
Quality of life questionnaire asking "I am content with the quality of my life right now".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Quality of Life
Quality of life questionnaire asking "I am content with the quality of my life right now".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Eating
Quality of life questionnaire asking "I am able to eat the foods i like".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Eating
Quality of life questionnaire asking "I am able to eat the foods i like".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Eating
Quality of life questionnaire asking "I am able to eat the foods i like".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Eating
Quality of life questionnaire asking "I am able to eat the foods i like".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Swallowing
Quality of life questionnaire asking "I can swallow naturally and easily".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Swallowing
Quality of life questionnaire asking "I can swallow naturally and easily".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Swallowing
Quality of life questionnaire asking "I can swallow naturally and easily".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Swallowing
Quality of life questionnaire asking "I can swallow naturally and easily".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Alcohol Consumption
Quality of life questionnaire asking "I drink alcohol (e.g. beer, wine)".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Alcohol Consumption
Quality of life questionnaire asking "I drink alcohol (e.g. beer, wine)".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Alcohol Consumption
Quality of life questionnaire asking "I drink alcohol (e.g. beer, wine)".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Alcohol Consumption
Quality of life questionnaire asking "I drink alcohol (e.g. beer, wine)".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Solid Foods
Quality of life questionnaire asking "I can eat solid foods".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Solid Foods
Quality of life questionnaire asking "I can eat solid foods".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Solid Foods
Quality of life questionnaire asking "I can eat solid foods".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.
Solid Foods
Quality of life questionnaire asking "I can eat solid foods".
The Categories were assigned a number. The categories were: Not at all (0), A little bit (1), Somewhat (2), Quite a bit (3), Very much (4). The mean was determined from each statement.