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Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome

Primary Purpose

Gilles de la Tourette's Syndrome

Status
Completed
Phase
Locations
France
Study Type
Observational
Intervention
Facial expression recognition of emotion
Sponsored by
University Hospital, Clermont-Ferrand
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an observational trial for Gilles de la Tourette's Syndrome focused on measuring Gilles de la Tourette's syndrome, Facial expression recognition of emotion, Frequency levels, Automatic and voluntary information treatment, Patient with Gilles de la Tourette's syndrome

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

  • Age : >18 years
  • Patient with a Gilles de la Tourette 's syndrome such as defined in the DSMIV
  • Stability of treatment >1 month
  • Mini Mental State > 26
  • Affiliation to social security
  • Agreement of patients

Exclusion Criteria:

  • Patients with cognitive disorders, dementia, mental retardation…
  • Patients with serious neurological pathologies
  • Patients with a vision contrast altered.
  • Patients who do not understand the words associated with an emotion
  • Pregnant women
  • Person who participate to an other study

Sites / Locations

  • CHU

Arms of the Study

Arm 1

Arm Type

Arm Label

2

Arm Description

One group with Gilles de la Tourette's Syndrome One group with healthy paired volunteers

Outcomes

Primary Outcome Measures

Facial expression recognition test

Secondary Outcome Measures

Lexical decision test

Full Information

First Posted
April 21, 2008
Last Updated
January 18, 2011
Sponsor
University Hospital, Clermont-Ferrand
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1. Study Identification

Unique Protocol Identification Number
NCT00664300
Brief Title
Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome
Official Title
Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome
Study Type
Observational

2. Study Status

Record Verification Date
January 2011
Overall Recruitment Status
Completed
Study Start Date
August 2007 (undefined)
Primary Completion Date
October 2008 (Actual)
Study Completion Date
October 2009 (Actual)

3. Sponsor/Collaborators

Name of the Sponsor
University Hospital, Clermont-Ferrand

4. Oversight

5. Study Description

Brief Summary
Gilles de la Tourette's syndrome is a childhood onset inherited neuropsychiatric disorder characterised by the presence of both multiple motor tics and one or more vocal tics (noises), with psychiatric and/or behaviour disorders (such as obsessive compulsive behaviour…). This disease is associated with an dopamine system imbalance which could be responsible of a specific trouble in the recognition in some facial expression. This has been already shown in Gilles de la Tourette patients with obsessive compulsive behaviour. We hypothesise that patients with Gilles de la Tourette's syndrome present a dysfunction of voluntary and automatic treatment of emotional information. The main purpose of this study is to show if patients with Gilles de la Tourette's syndrome present a lack of specific facial expression recognition of emotion and determinate more precisely if this alteration involves the cortical way (high frequency way) or the under cortical way (low frequency way).
Detailed Description
20 patients with Gilles de la Tourette's syndrome compared to 20 healthy paired volunteers. Study progress (patients): Inclusion visit : Psychiatric evaluation Psychological evaluation Ophthalmic visit Protocol : Facial expression recognition test Lexical decision test Study progress (healthy volunteers): Psychiatric evaluation Ophthalmic visit Facial expression recognition test Lexical decision test

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Gilles de la Tourette's Syndrome
Keywords
Gilles de la Tourette's syndrome, Facial expression recognition of emotion, Frequency levels, Automatic and voluntary information treatment, Patient with Gilles de la Tourette's syndrome

7. Study Design

Enrollment
60 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
2
Arm Description
One group with Gilles de la Tourette's Syndrome One group with healthy paired volunteers
Intervention Type
Behavioral
Intervention Name(s)
Facial expression recognition of emotion
Intervention Description
Facial expression recognition test Lexical decision test
Primary Outcome Measure Information:
Title
Facial expression recognition test
Time Frame
% of exact responses
Secondary Outcome Measure Information:
Title
Lexical decision test
Time Frame
The time to respond

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: Age : >18 years Patient with a Gilles de la Tourette 's syndrome such as defined in the DSMIV Stability of treatment >1 month Mini Mental State > 26 Affiliation to social security Agreement of patients Exclusion Criteria: Patients with cognitive disorders, dementia, mental retardation… Patients with serious neurological pathologies Patients with a vision contrast altered. Patients who do not understand the words associated with an emotion Pregnant women Person who participate to an other study
Study Population Description
30 patients with Gilles de la Tourette's Syndrome and 30 healthy paired volunteers (control group)
Sampling Method
Probability Sample
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Isabelle Jalenques, PUPH
Organizational Affiliation
University Hospital, Clermont-Ferrand
Official's Role
Principal Investigator
Facility Information:
Facility Name
CHU
City
Clermont-Ferrand
ZIP/Postal Code
63003
Country
France

12. IPD Sharing Statement

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Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome

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