Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome
Primary Purpose
Gilles de la Tourette's Syndrome
Status
Completed
Phase
Locations
France
Study Type
Observational
Intervention
Facial expression recognition of emotion
Sponsored by
About this trial
This is an observational trial for Gilles de la Tourette's Syndrome focused on measuring Gilles de la Tourette's syndrome, Facial expression recognition of emotion, Frequency levels, Automatic and voluntary information treatment, Patient with Gilles de la Tourette's syndrome
Eligibility Criteria
Inclusion Criteria:
- Age : >18 years
- Patient with a Gilles de la Tourette 's syndrome such as defined in the DSMIV
- Stability of treatment >1 month
- Mini Mental State > 26
- Affiliation to social security
- Agreement of patients
Exclusion Criteria:
- Patients with cognitive disorders, dementia, mental retardation…
- Patients with serious neurological pathologies
- Patients with a vision contrast altered.
- Patients who do not understand the words associated with an emotion
- Pregnant women
- Person who participate to an other study
Sites / Locations
- CHU
Arms of the Study
Arm 1
Arm Type
Arm Label
2
Arm Description
One group with Gilles de la Tourette's Syndrome One group with healthy paired volunteers
Outcomes
Primary Outcome Measures
Facial expression recognition test
Secondary Outcome Measures
Lexical decision test
Full Information
NCT ID
NCT00664300
First Posted
April 21, 2008
Last Updated
January 18, 2011
Sponsor
University Hospital, Clermont-Ferrand
1. Study Identification
Unique Protocol Identification Number
NCT00664300
Brief Title
Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome
Official Title
Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome
Study Type
Observational
2. Study Status
Record Verification Date
January 2011
Overall Recruitment Status
Completed
Study Start Date
August 2007 (undefined)
Primary Completion Date
October 2008 (Actual)
Study Completion Date
October 2009 (Actual)
3. Sponsor/Collaborators
Name of the Sponsor
University Hospital, Clermont-Ferrand
4. Oversight
5. Study Description
Brief Summary
Gilles de la Tourette's syndrome is a childhood onset inherited neuropsychiatric disorder characterised by the presence of both multiple motor tics and one or more vocal tics (noises), with psychiatric and/or behaviour disorders (such as obsessive compulsive behaviour…).
This disease is associated with an dopamine system imbalance which could be responsible of a specific trouble in the recognition in some facial expression. This has been already shown in Gilles de la Tourette patients with obsessive compulsive behaviour.
We hypothesise that patients with Gilles de la Tourette's syndrome present a dysfunction of voluntary and automatic treatment of emotional information.
The main purpose of this study is to show if patients with Gilles de la Tourette's syndrome present a lack of specific facial expression recognition of emotion and determinate more precisely if this alteration involves the cortical way (high frequency way) or the under cortical way (low frequency way).
Detailed Description
20 patients with Gilles de la Tourette's syndrome compared to 20 healthy paired volunteers.
Study progress (patients):
Inclusion visit :
Psychiatric evaluation Psychological evaluation
Ophthalmic visit
Protocol :
Facial expression recognition test Lexical decision test
Study progress (healthy volunteers):
Psychiatric evaluation Ophthalmic visit Facial expression recognition test Lexical decision test
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Gilles de la Tourette's Syndrome
Keywords
Gilles de la Tourette's syndrome, Facial expression recognition of emotion, Frequency levels, Automatic and voluntary information treatment, Patient with Gilles de la Tourette's syndrome
7. Study Design
Enrollment
60 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
2
Arm Description
One group with Gilles de la Tourette's Syndrome One group with healthy paired volunteers
Intervention Type
Behavioral
Intervention Name(s)
Facial expression recognition of emotion
Intervention Description
Facial expression recognition test Lexical decision test
Primary Outcome Measure Information:
Title
Facial expression recognition test
Time Frame
% of exact responses
Secondary Outcome Measure Information:
Title
Lexical decision test
Time Frame
The time to respond
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
Age : >18 years
Patient with a Gilles de la Tourette 's syndrome such as defined in the DSMIV
Stability of treatment >1 month
Mini Mental State > 26
Affiliation to social security
Agreement of patients
Exclusion Criteria:
Patients with cognitive disorders, dementia, mental retardation…
Patients with serious neurological pathologies
Patients with a vision contrast altered.
Patients who do not understand the words associated with an emotion
Pregnant women
Person who participate to an other study
Study Population Description
30 patients with Gilles de la Tourette's Syndrome and 30 healthy paired volunteers (control group)
Sampling Method
Probability Sample
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Isabelle Jalenques, PUPH
Organizational Affiliation
University Hospital, Clermont-Ferrand
Official's Role
Principal Investigator
Facility Information:
Facility Name
CHU
City
Clermont-Ferrand
ZIP/Postal Code
63003
Country
France
12. IPD Sharing Statement
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Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome
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