Adolescent Substance Abuse: Progressive Treatment (ADAPT)
Primary Purpose
Substance Abuse
Status
Completed
Phase
Phase 1
Locations
United States
Study Type
Interventional
Intervention
CBT, Cognitive Behavioral Therapy
FFT, Family Functional Therapy
Sponsored by
About this trial
This is an interventional treatment trial for Substance Abuse focused on measuring adolescent substance abuse
Eligibility Criteria
Inclusion Criteria:
- 13 to 18 years if age
- Meet DSM-IV (APA, 1994) diagnostic criteria for substance abuse or dependence
- Live in the Albuquerque metropolitan area or surrounding communities
- Sufficient residential stability to permit probable contact at follow-up (e.g., not homeless at time of intake).
Exclusion Criteria:
- There is evidence of psychotic or organic state of sufficient severity to interfere with the understanding of study instruments and procedures
- The adolescent is deemed dangerous to self or others during evaluation
- Services other than outpatient treatment are required for the adolescent (e.g., inpatient, detoxification)
- Marijuana use is reported as being less than 13% of days in the previous 90 days.
Sites / Locations
- Oregon Res. Inst. Center for Family & Adolescent Research (CFAR)
Arms of the Study
Arm 1
Arm 2
Arm Type
Active Comparator
Active Comparator
Arm Label
1
2
Arm Description
Eight weeks of individual CBT for adolescents who have completed six weeks of group therapy and continue to use drugs.
Eight weeks of FFT for adolescents who have received six weeks of group therapy and continue to use drugs.
Outcomes
Primary Outcome Measures
Urine drug screens
Secondary Outcome Measures
Full Information
NCT ID
NCT00680576
First Posted
May 16, 2008
Last Updated
October 8, 2014
Sponsor
Oregon Research Institute
1. Study Identification
Unique Protocol Identification Number
NCT00680576
Brief Title
Adolescent Substance Abuse: Progressive Treatment
Acronym
ADAPT
Study Type
Interventional
2. Study Status
Record Verification Date
October 2014
Overall Recruitment Status
Completed
Study Start Date
March 2008 (undefined)
Primary Completion Date
August 2013 (Actual)
Study Completion Date
August 2013 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Oregon Research Institute
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
The purpose of this study is to find out more about how to provide effective further treatment for adolescents who have received six weeks of group therapy for substance-use problems and continue to use drugs. Treatments used in the study include a group therapy (MET/CBT), an individual therapy (CBT), and a family therapy (FFT). The study will look at whether abstinence or a very low level of use is a better guide for deciding whether further treatment is needed, how well different combinations of treatment work to reduce substance use, and whether it is possible to predict in advance which adolescents will respond best to which types of treatment. Study investigators expect that a treatment strategy using what is learned about these issues in the first half of the project to develop an "adaptive" treatment model will work better than a "fixed" treatment to reduce adolescent substance use.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Substance Abuse
Keywords
adolescent substance abuse
7. Study Design
Primary Purpose
Treatment
Study Phase
Phase 1
Interventional Study Model
Factorial Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
140 (Actual)
8. Arms, Groups, and Interventions
Arm Title
1
Arm Type
Active Comparator
Arm Description
Eight weeks of individual CBT for adolescents who have completed six weeks of group therapy and continue to use drugs.
Arm Title
2
Arm Type
Active Comparator
Arm Description
Eight weeks of FFT for adolescents who have received six weeks of group therapy and continue to use drugs.
Intervention Type
Behavioral
Intervention Name(s)
CBT, Cognitive Behavioral Therapy
Intervention Description
Eight weekly sessions of individual Cognitive Behavioral Therapy, to develop skills enabling adolescents stop or reduce their drug use.
Intervention Type
Behavioral
Intervention Name(s)
FFT, Family Functional Therapy
Intervention Description
Eight weekly sessions of Functional Family Therapy designed to strengthen family relationships and build skills to help the adolescent stop or reduce his/her drug use.
Primary Outcome Measure Information:
Title
Urine drug screens
Time Frame
Pretx, 6, 14 and 22 weeks, 3 and 6 months after initial treatment session
10. Eligibility
Sex
All
Minimum Age & Unit of Time
13 Years
Maximum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
13 to 18 years if age
Meet DSM-IV (APA, 1994) diagnostic criteria for substance abuse or dependence
Live in the Albuquerque metropolitan area or surrounding communities
Sufficient residential stability to permit probable contact at follow-up (e.g., not homeless at time of intake).
Exclusion Criteria:
There is evidence of psychotic or organic state of sufficient severity to interfere with the understanding of study instruments and procedures
The adolescent is deemed dangerous to self or others during evaluation
Services other than outpatient treatment are required for the adolescent (e.g., inpatient, detoxification)
Marijuana use is reported as being less than 13% of days in the previous 90 days.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Holly B Waldron, Ph.D.
Organizational Affiliation
Oregon Research Institute Center for Family and Adolescent Research (ORI/CFAR)
Official's Role
Principal Investigator
Facility Information:
Facility Name
Oregon Res. Inst. Center for Family & Adolescent Research (CFAR)
City
Albuquerque
State/Province
New Mexico
ZIP/Postal Code
87102
Country
United States
12. IPD Sharing Statement
Learn more about this trial
Adolescent Substance Abuse: Progressive Treatment
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