Diet and Physical Activity Change or Usual Care in Improving Progression-Free Survival in Patients With Previously Treated Stage II, III, or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube Mucinous Adenocarcinoma
About this trial
This is an interventional prevention trial for Fallopian Tube Clear Cell Adenocarcinoma
Eligibility Criteria
Inclusion Criteria:
- Patients with a histological diagnosis of epithelial ovarian cancer, fallopian tube or primary peritoneal carcinoma, clinical stage II, III or IV at diagnosis
- Patients with the following histologic epithelial cell types are eligible: serous adenocarcinoma, endometrioid adenocarcinoma, mucinous adenocarcinoma, undifferentiated carcinoma, clear cell adenocarcinoma, mixed epithelial carcinoma, transitional cell carcinoma, malignant Brenner?s tumor or adenocarcinoma not otherwise specified (N.O.S.); however, the histologic features of the tumor must be compatible with a primary M?llerian epithelial adenocarcinoma
- Patients must have completed all primary chemotherapy and consolidation therapy (if administered) at least 6 weeks, and no more than 6 months and 2 weeks, prior to enrollment and must be in complete remission; consolidation therapy is defined as any chemotherapy or biological therapy used for a patient who has completed at least four courses of primary chemotherapy and had documented complete remission prior to initiation of such chemotherapy (chemo) or biological therapy
- Patients must have achieved a documented complete response to treatment based on normal cancer antigen (CA)-125 (per the institution?s upper limit of normal) and computed tomography (CT) scan or magnetic resonance imaging (MRI) with contrast (i.e. there must be no clinical evidence of persistent or recurrent disease based on CA-125 and CT scan or MRI with contrast)
- Patients must have a Gynecologic Oncology Group (GOG) performance grade of 0, 1, or 2
- Patients must not be currently enrolled in an ongoing (participating for 6 months or longer) medically prescribed diet or physical activity regimen
- Patients must have no other chronic disease that would preclude randomization into a lifestyle intervention trial; such diseases include recent myocardial infarction or unstable angina (in the previous 6 months), chronic hepatitis, rheumatoid disease, renal or hepatic disease/dysfunction and diabetics receiving insulin; or other clinical condition limiting ability to walk (recent leg fracture, significant osteoarthritis, related orthopedic conditions, degenerative neurological conditions, etc.)
- Patients must not have a serious psychiatric illness (e.g. lifetime bipolar disorder, schizophrenia or other psychosis, serious personality disorder, severe major depressive disorder or recent suicide or psychiatric hospitalization) (previous 12 months), or a history of an eating disorder (anorexia nervosa or bulimia nervosa)
- Patients must complete all pre-entry assessments
- Patients must have signed an approved informed consent and authorization permitting release of personal health information
- Patients must be willing to provide name and appropriate telephone contact information and be willing to be contacted periodically via telephone by The University of Arizona Cancer Center (AZCC) staff for completion of individualized lifestyle intervention coaching, completion of the Pittsburgh Sleep Quality Index, and for clarification of patient-completed responses if necessary; patient must be willing to have Arizona Food Frequency Questionnaire (AFFQ), Arizona Physical Activity Questionnaire (APAQ), baseline questionnaire, and personal contact information sent to AZCC
Exclusion Criteria:
- Patients with GOG performance grade of 3 or 4
- Patients may not have a history of other invasive malignancies within the last five years, with the exception of non-melanoma skin cancer or stage 1A endometrioid adenocarcinoma of the uterus
- Patients diagnosed with chronic disease/illness precluding their participation (i.e., diabetics receiving insulin, myocardial infarction or unstable angina within previous 6 months, chronic hepatitis, rheumatoid disease, renal or hepatic disease/dysfunction)
- Patients with a histological diagnosis of clinical stage I epithelial ovarian cancer, fallopian tube or primary peritoneal carcinoma
- Patients who are currently undergoing treatment (primary or consolidation) for stage II, III or IV ovarian, fallopian tube or primary peritoneal cancer or who completed treatment less than six weeks ago
- Patients with a life expectancy of less than one year
- Patients with body mass index (BMI) < 20 kg/m^2
- Vegan vegetarians
- Patients enrolled in a weight loss program or who are taking weight loss medications or dietary supplements and are unwilling to discontinue
- Patients who have participated in a marathon, triathlon, or other endurance-related physical activity within the previous 24 months
Patients who have had surgery for weight loss
- Note: women will not be excluded if their baseline lifestyle assessment indicates a healthy eating and moderate physical activity with the exception of the exclusion criteria above
Sites / Locations
- University of Alabama at Birmingham Cancer CenterRecruiting
- Tennessee Valley Gynecologic Oncology
- Anchorage Associates in Radiation MedicineRecruiting
- Alaska Breast Care and Surgery LLCRecruiting
- Alaska Oncology and Hematology LLCRecruiting
- Alaska Women's Cancer CareRecruiting
- Anchorage Oncology CentreRecruiting
- Katmai Oncology GroupRecruiting
- Providence Alaska Medical CenterRecruiting
- Fairbanks Memorial HospitalRecruiting
- University of Arizona Cancer Center at Saint Joseph'sRecruiting
- Gynecologic Oncology Group of Arizona
- Saint Joseph's Hospital and Medical Center
- University of Arizona Cancer Center-North CampusRecruiting
- The University of Arizona Medical Center-University CampusRecruiting
- CHI Saint Vincent Cancer Center Hot SpringsRecruiting
- University of Arkansas for Medical SciencesRecruiting
- Sutter Auburn Faith HospitalRecruiting
- Sutter Cancer Centers Radiation Oncology Services-AuburnRecruiting
- Alta Bates Summit Medical Center-Herrick CampusRecruiting
- Providence Saint Joseph Medical Center/Disney Family Cancer CenterRecruiting
- Mills-Peninsula Medical CenterRecruiting
- Sutter Cancer Centers Radiation Oncology Services-Cameron ParkRecruiting
- Eden Hospital Medical CenterRecruiting
- John Muir Medical Center-Concord CampusRecruiting
- Sutter Davis HospitalRecruiting
- City of Hope Comprehensive Cancer CenterRecruiting
- Palo Alto Medical Foundation-FremontRecruiting
- Kaiser Permanente-IrvineRecruiting
- UC San Diego Moores Cancer CenterRecruiting
- Kaiser Permanente Los Angeles Medical CenterRecruiting
- Los Angeles County-USC Medical Center
- USC / Norris Comprehensive Cancer Center
- Cedars Sinai Medical CenterRecruiting
- UCLA / Jonsson Comprehensive Cancer CenterRecruiting
- Memorial Medical CenterRecruiting
- Palo Alto Medical Foundation-Camino DivisionRecruiting
- Palo Alto Medical Foundation-Gynecologic OncologyRecruiting
- Saint Joseph Hospital - OrangeRecruiting
- Palo Alto Medical Foundation Health CareRecruiting
- Sutter Cancer Centers Radiation Oncology Services-RosevilleRecruiting
- Sutter Roseville Medical CenterRecruiting
- Sutter Medical Center SacramentoRecruiting
- University of California Davis Comprehensive Cancer Center
- University of California San DiegoRecruiting
- California Pacific Medical Center-Pacific CampusRecruiting
- Palo Alto Medical Foundation-Santa CruzRecruiting
- Sutter Pacific Medical FoundationRecruiting
- Palo Alto Medical Foundation-SunnyvaleRecruiting
- Olive View-University of California Los Angeles Medical Center
- Sutter Cancer Centers Radiation Oncology Services-VacavilleRecruiting
- Sutter Solano Medical Center/Cancer CenterRecruiting
- John Muir Medical Center-Walnut Creek
- Rocky Mountain Cancer Centers-AuroraRecruiting
- The Medical Center of Aurora
- University of Colorado HospitalRecruiting
- Boulder Community HospitalRecruiting
- Rocky Mountain Cancer Centers-BoulderRecruiting
- Penrose-Saint Francis HealthcareRecruiting
- Rocky Mountain Cancer Centers-PenroseRecruiting
- Porter Adventist HospitalRecruiting
- Colorado Blood Cancer InstituteRecruiting
- Presbyterian - Saint Lukes Medical Center - Health OneRecruiting
- Rocky Mountain Cancer Centers-MidtownRecruiting
- SCL Health Saint Joseph HospitalRecruiting
- Rocky Mountain Cancer Centers-RoseRecruiting
- Rose Medical CenterRecruiting
- Colorado Cancer Research Program NCORPRecruiting
- Mercy Medical CenterRecruiting
- Southwest Oncology PCRecruiting
- Comprehensive Cancer Care and Research Institute of Colorado LLCRecruiting
- Swedish Medical CenterRecruiting
- Poudre Valley HospitalRecruiting
- Mountain Blue Cancer Care CenterRecruiting
- North Colorado Medical CenterRecruiting
- Rocky Mountain Cancer Centers-Greenwood Village
- Rocky Mountain Cancer Centers-LakewoodRecruiting
- Saint Anthony HospitalRecruiting
- Rocky Mountain Cancer Centers-LittletonRecruiting
- Littleton Adventist HospitalRecruiting
- Rocky Mountain Cancer Centers-Sky RidgeRecruiting
- Sky Ridge Medical Center
- Longmont United HospitalRecruiting
- Rocky Mountain Cancer Centers-LongmontRecruiting
- McKee Medical CenterRecruiting
- Parker Adventist HospitalRecruiting
- Rocky Mountain Cancer Centers-ParkerRecruiting
- Saint Mary Corwin Medical CenterRecruiting
- Rocky Mountain Cancer Centers - PuebloRecruiting
- Rocky Mountain Cancer Centers-ThorntonRecruiting
- SCL Health Lutheran Medical CenterRecruiting
- Saint Vincent's Medical CenterRecruiting
- Danbury Hospital
- University of ConnecticutRecruiting
- Hartford Hospital
- Smilow Cancer Hospital Care Center at Saint FrancisRecruiting
- Middlesex HospitalRecruiting
- The Hospital of Central Connecticut
- Yale UniversityRecruiting
- Beebe Medical CenterRecruiting
- Christiana Gynecologic Oncology LLC
- Delaware Clinical and Laboratory Physicians PARecruiting
- Helen F Graham Cancer CenterRecruiting
- Medical Oncology Hematology Consultants PARecruiting
- Regional Hematology and Oncology PARecruiting
- Christiana Care Health System-Christiana HospitalRecruiting
- Beebe Health CampusRecruiting
- Nanticoke Memorial HospitalRecruiting
- Christiana Care Health System-Wilmington HospitalRecruiting
- Florida Hospital OrlandoRecruiting
- UF Cancer Center at Orlando Health
- Sarasota Memorial HospitalRecruiting
- Piedmont Hospital
- Northside HospitalRecruiting
- Augusta University Medical CenterRecruiting
- John B Amos Cancer Center
- Northside Hospital-Forsyth
- Dekalb Medical CenterRecruiting
- Northeast Georgia Medical Center-Gainesville
- Central Georgia Gynecologic Oncology
- Memorial University Medical Center
- Lewis Cancer and Research Pavilion at Saint Joseph's/CandlerRecruiting
- Hawaii Cancer Care Inc-POB IIRecruiting
- Queen's Medical CenterRecruiting
- University of Hawaii Cancer CenterRecruiting
- Kapiolani Medical Center for Women and ChildrenRecruiting
- Saint Alphonsus Cancer Care Center-BoiseRecruiting
- Saint Luke's Mountain States Tumor InstituteRecruiting
- Saint Alphonsus Cancer Care Center-CaldwellRecruiting
- Kootenai Medical CenterRecruiting
- Walter Knox Memorial HospitalRecruiting
- Saint Luke's Mountain States Tumor Institute - FruitlandRecruiting
- Idaho Urologic Institute-MeridianRecruiting
- Saint Luke's Mountain States Tumor Institute - MeridianRecruiting
- Saint Alphonsus Medical Center-NampaRecruiting
- Saint Luke's Mountain States Tumor Institute - NampaRecruiting
- Kootenai Cancer CenterRecruiting
- Kootenai Cancer ClinicRecruiting
- Saint Luke's Mountain States Tumor Institute-Twin FallsRecruiting
- Rush - Copley Medical CenterRecruiting
- Saint Joseph Medical Center
- Illinois CancerCare-BloomingtonRecruiting
- Illinois CancerCare-CantonRecruiting
- Memorial Hospital of CarbondaleRecruiting
- Illinois CancerCare-CarthageRecruiting
- Centralia Oncology ClinicRecruiting
- Northwestern UniversityRecruiting
- Rush University Medical CenterRecruiting
- University of Chicago Comprehensive Cancer CenterRecruiting
- Carle on VermilionRecruiting
- Cancer Care Specialists of Central IllinoisRecruiting
- Decatur Memorial HospitalRecruiting
- Carle Physician Group-EffinghamRecruiting
- Crossroads Cancer CenterRecruiting
- Illinois CancerCare-EurekaRecruiting
- Illinois CancerCare-GalesburgRecruiting
- Western Illinois Cancer Treatment CenterRecruiting
- Northwestern Medicine Cancer Center Delnor
- Sudarshan K Sharma MD Limted-Gynecologic OncologyRecruiting
- Illinois CancerCare-Kewanee ClinicRecruiting
- Illinois CancerCare-MacombRecruiting
- Carle Physician Group-Mattoon/CharlestonRecruiting
- Good Samaritan Regional Health Center
- UC Comprehensive Cancer Center at Silver CrossRecruiting
- Advocate Christ Medical Center
- Illinois CancerCare-Ottawa ClinicRecruiting
- Radiation Oncology of Northern Illinois
- Illinois CancerCare-PekinRecruiting
- OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment CenterRecruiting
- Methodist Medical Center of IllinoisRecruiting
- Illinois CancerCare-PeoriaRecruiting
- OSF Saint Francis Radiation Oncology at Peoria Cancer CenterRecruiting
- OSF Saint Francis Medical CenterRecruiting
- Illinois CancerCare-PeruRecruiting
- Valley Radiation OncologyRecruiting
- Illinois CancerCare-PrincetonRecruiting
- Central Illinois Hematology Oncology Center
- Southern Illinois University School of MedicineRecruiting
- Springfield ClinicRecruiting
- Memorial Medical CenterRecruiting
- Cancer Care Specialists of Illinois-SwanseaRecruiting
- Carle Cancer CenterRecruiting
- The Carle Foundation HospitalRecruiting
- Northwestern Medicine Cancer Center Warrenville
- Rush-Copley Healthcare CenterRecruiting
- Michiana Hematology Oncology PC-Crown Point
- Elkhart Clinic
- Michiana Hematology Oncology PC-Elkhart
- Elkhart General Hospital
- Indiana University/Melvin and Bren Simon Cancer CenterRecruiting
- Saint Vincent Hospital and Health Care CenterRecruiting
- Community Howard Regional Health
- IU Health La Porte Hospital
- Michiana Hematology Oncology PC-Mishawaka
- Saint Joseph Regional Medical Center-Mishawaka
- Michiana Hematology Oncology PC-Plymouth
- Memorial Hospital of South Bend
- Michiana Hematology Oncology PC-South Bend
- South Bend Clinic
- Northern Indiana Cancer Research ConsortiumRecruiting
- Michiana Hematology Oncology PC-Westville
- Medical Oncology and Hematology Associates-West Des MoinesRecruiting
- Mercy Cancer Center-West LakesRecruiting
- Alegent Health Mercy HospitalRecruiting
- Greater Regional Medical CenterRecruiting
- Medical Oncology and Hematology Associates-LaurelRecruiting
- Mercy Medical Center - Des MoinesRecruiting
- Mercy Medical Center-West LakesRecruiting
- Cancer Center of Kansas - ChanuteRecruiting
- Cancer Center of Kansas - Dodge CityRecruiting
- Cancer Center of Kansas - El DoradoRecruiting
- Cancer Center of Kansas - Fort ScottRecruiting
- Cancer Center of Kansas-IndependenceRecruiting
- Providence Medical Center
- University of Kansas Cancer CenterRecruiting
- Cancer Center of Kansas-KingmanRecruiting
- Lawrence Memorial HospitalRecruiting
- Kansas Institute of Medicine Cancer and Blood Center
- Minimally Invasive Surgery Hospital
- Cancer Center of Kansas-LiberalRecruiting
- Cancer Center of Kansas-ManhattanRecruiting
- Cancer Center of Kansas - McPhersonRecruiting
- Cancer Center of Kansas - NewtonRecruiting
- Menorah Medical Center
- Saint Luke's South Hospital
- Cancer Center of Kansas - ParsonsRecruiting
- Kansas City NCI Community Oncology Research ProgramRecruiting
- Cancer Center of Kansas - PrattRecruiting
- Cancer Center of Kansas - SalinaRecruiting
- Cancer Center of Kansas - WellingtonRecruiting
- Associates In Womens HealthRecruiting
- Cancer Center of Kansas-Wichita Medical Arts TowerRecruiting
- Cancer Center of Kansas - WichitaRecruiting
- Via Christi Regional Medical CenterRecruiting
- Wichita NCI Community Oncology Research ProgramRecruiting
- Cancer Center of Kansas - WinfieldRecruiting
- Flaget Memorial HospitalRecruiting
- Commonwealth Cancer Center-CorbinRecruiting
- Saint Elizabeth Medical Center SouthRecruiting
- Saint Joseph Radiation Oncology Resource CenterRecruiting
- Saint Joseph Hospital EastRecruiting
- University of Kentucky/Markey Cancer CenterRecruiting
- Saint Joseph LondonRecruiting
- Jewish HospitalRecruiting
- Norton Hospital Pavilion and Medical Campus
- Norton Suburban Hospital and Medical Campus
- Saints Mary and Elizabeth HospitalRecruiting
- Jewish Hospital Medical Center NortheastRecruiting
- Jewish Hospital Medical Center SouthRecruiting
- Hematology/Oncology Clinic LLP
- Woman's HospitalRecruiting
- Tulane University Health Sciences Center
- Maine Medical Center-Bramhall CampusRecruiting
- Maine Medical Center- Scarborough CampusRecruiting
- Greater Baltimore Medical CenterRecruiting
- Walter Reed National Military Medical CenterRecruiting
- Tufts Medical CenterRecruiting
- Lahey Hospital and Medical CenterRecruiting
- University of Massachusetts Memorial Health Care
- Michigan Cancer Research Consortium NCORP
- Saint Joseph Mercy HospitalRecruiting
- University of Michigan Comprehensive Cancer Center
- Bronson Battle CreekRecruiting
- Spectrum Health Big Rapids Hospital
- IHA Hematology Oncology Consultants-BrightonRecruiting
- Saint Joseph Mercy BrightonRecruiting
- IHA Hematology Oncology Consultants-CantonRecruiting
- Saint Joseph Mercy CantonRecruiting
- Caro Cancer CenterRecruiting
- IHA Hematology Oncology Consultants-ChelseaRecruiting
- Saint Joseph Mercy ChelseaRecruiting
- Hematology Oncology Consultants-ClarkstonRecruiting
- Newland Medical Associates-ClarkstonRecruiting
- Beaumont Hospital-DearbornRecruiting
- Wayne State University/Karmanos Cancer Institute
- Saint John Hospital and Medical CenterRecruiting
- Great Lakes Cancer Management Specialists-Doctors ParkRecruiting
- Weisberg Cancer Treatment Center
- Genesee Cancer and Blood Disease Treatment CenterRecruiting
- Genesee Hematology Oncology PCRecruiting
- Genesys Hurley Cancer InstituteRecruiting
- Hurley Medical CenterRecruiting
- Cancer Research Consortium of West Michigan NCORP
- Mercy Health Saint Mary'sRecruiting
- Spectrum Health at Butterworth CampusRecruiting
- Great Lakes Cancer Management Specialists-Van Elslander Cancer CenterRecruiting
- Lymphoma Clinic of MichiganRecruiting
- Michigan Breast Specialists-Grosse Pointe WoodsRecruiting
- Allegiance Health
- Borgess Medical Center
- Bronson Methodist Hospital
- West Michigan Cancer CenterRecruiting
- Sparrow HospitalRecruiting
- Hope Cancer ClinicRecruiting
- Saint Mary Mercy HospitalRecruiting
- Great Lakes Cancer Management Specialists-Macomb Medical CampusRecruiting
- Michigan Breast Specialists-Macomb TownshipRecruiting
- Saint Mary's Oncology/Hematology Associates of MarletteRecruiting
- Mercy Health Mercy CampusRecruiting
- Lakeland Community HospitalRecruiting
- 21st Century Oncology-PontiacRecruiting
- Hope Cancer CenterRecruiting
- Newland Medical Associates-PontiacRecruiting
- Saint Joseph Mercy OaklandRecruiting
- Lake Huron Medical Center
- Spectrum Health Reed City HospitalRecruiting
- Great Lakes Cancer Management Specialists-Rochester HillsRecruiting
- William Beaumont Hospital-Royal Oak
- Saint Mary's of MichiganRecruiting
- Oncology Hematology Associates of Saginaw Valley PCRecruiting
- Lakeland HospitalRecruiting
- Marie Yeager Cancer CenterRecruiting
- Bhadresh Nayak MD PC-Sterling HeightsRecruiting
- Saint Joseph Health System-Tawas CityRecruiting
- Munson Medical CenterRecruiting
- William Beaumont Hospital - Troy
- Advanced Breast Care Center PLLCRecruiting
- Bhadresh Nayak MD PC-WarrenRecruiting
- Great Lakes Cancer Management Specialists-Macomb Professional BuildingRecruiting
- Macomb Hematology Oncology PCRecruiting
- Michigan Breast Specialists-WarrenRecruiting
- Saint John Macomb-Oakland HospitalRecruiting
- Saint Mary's Oncology/Hematology Associates of West BranchRecruiting
- Metro Health HospitalRecruiting
- Huron Gastroenterology PCRecruiting
- IHA Hematology Oncology Consultants-Ann ArborRecruiting
- Sanford Clinic North-BemidgiRecruiting
- Fairview Ridges HospitalRecruiting
- Mercy HospitalRecruiting
- Fairview-Southdale HospitalRecruiting
- Unity HospitalRecruiting
- Hutchinson Area Health Care
- Fairview Maple Grove Medical CenterRecruiting
- Minnesota Oncology Hematology PA-MaplewoodRecruiting
- Saint John's Hospital - HealtheastRecruiting
- Abbott-Northwestern HospitalRecruiting
- Hennepin County Medical CenterRecruiting
- Health Partners IncRecruiting
- New Ulm Medical CenterRecruiting
- North Memorial Medical Health CenterRecruiting
- Metro Minnesota Community Oncology Research ConsortiumRecruiting
- Park Nicollet Clinic - Saint Louis ParkRecruiting
- Park Nicollet Frauenshuh Cancer Center
- Regions HospitalRecruiting
- United HospitalRecruiting
- Saint Francis Regional Medical CenterRecruiting
- Lakeview HospitalRecruiting
- Ridgeview Medical CenterRecruiting
- Rice Memorial HospitalRecruiting
- Minnesota Oncology Hematology PA-WoodburyRecruiting
- Fairview Lakes Medical CenterRecruiting
- Saint Dominic-Jackson Memorial HospitalRecruiting
- Central Care Cancer Center-Carrie J Babb Cancer Center
- Parkland Health Center-Bonne TerreRecruiting
- Saint Francis Medical CenterRecruiting
- Southeast Cancer CenterRecruiting
- Centerpoint Medical Center LLC
- Capital Region Medical Center-Goldschmidt Cancer CenterRecruiting
- Saint Luke's Hospital of Kansas City
- Heartland Hematology and Oncology Associates Incorporated
- Research Medical Center
- Saint Luke's East - Lee's Summit
- Liberty Radiation Oncology Center
- Delbert Day Cancer Institute at PCRMC
- Mercy Clinic-Rolla-Cancer and Hematology
- Heartland Regional Medical Center
- Saint Joseph Oncology Inc
- Barnes-Jewish HospitalRecruiting
- Washington University School of MedicineRecruiting
- Missouri Baptist Medical CenterRecruiting
- Sainte Genevieve County Memorial HospitalRecruiting
- Cancer Research for the Ozarks NCORP
- Mercy Hospital Springfield
- CoxHealth South HospitalRecruiting
- Missouri Baptist Sullivan HospitalRecruiting
- Missouri Baptist Outpatient Center-Sunset HillsRecruiting
- Community Hospital of AnacondaRecruiting
- Billings Clinic Cancer CenterRecruiting
- Saint Vincent Healthcare
- Montana Cancer Consortium NCORPRecruiting
- Bozeman Deaconess HospitalRecruiting
- Saint James Community Hospital and Cancer Treatment Center
- Benefis Healthcare- Sletten Cancer InstituteRecruiting
- Great Falls ClinicRecruiting
- Saint Peter's Community HospitalRecruiting
- Kalispell Regional Medical CenterRecruiting
- Saint Patrick Hospital - Community HospitalRecruiting
- Community Medical HospitalRecruiting
- CHI Health Saint FrancisRecruiting
- Heartland Hematology and OncologyRecruiting
- CHI Health Good SamaritanRecruiting
- Saint Elizabeth Regional Medical CenterRecruiting
- Nebraska Methodist HospitalRecruiting
- Alegent Health Immanuel Medical CenterRecruiting
- Hematology and Oncology Consultants PCRecruiting
- Alegent Health Bergan Mercy Medical CenterRecruiting
- Alegent Health Lakeside HospitalRecruiting
- Creighton University Medical CenterRecruiting
- Midlands Community HospitalRecruiting
- Women's Cancer Center of NevadaRecruiting
- Center of Hope at Renown Medical Center
- Renown Regional Medical Center
- Wentworth-Douglass HospitalRecruiting
- Dartmouth Hitchcock Medical CenterRecruiting
- Norris Cotton Cancer Center-ManchesterRecruiting
- Norris Cotton Cancer Center-NashuaRecruiting
- Ocean Medical Center
- Cooper Hospital University Medical CenterRecruiting
- Hackensack University Medical Center
- Morristown Medical Center
- Virtua MemorialRecruiting
- Jersey Shore Medical Center
- Rutgers Cancer Institute of New Jersey
- Riverview Medical Center/Booker Cancer Center
- Overlook Hospital
- MD Anderson Cancer Center at Cooper-VoorheesRecruiting
- Virtua VoorheesRecruiting
- University of New Mexico Cancer Center
- Southwest Gynecologic Oncology Associates Inc
- Women's Cancer Care Associates LLC
- Montefiore Medical Center-Einstein Campus
- Montefiore Medical Center-Weiler Hospital
- Montefiore Medical Center - Moses Campus
- Queens Hospital Center
- North Shore University HospitalRecruiting
- NYU Winthrop HospitalRecruiting
- Long Island Jewish Medical CenterRecruiting
- Northwell Health/Center for Advanced MedicineRecruiting
- Lenox Hill HospitalRecruiting
- Stony Brook University Medical CenterRecruiting
- State University of New York Upstate Medical UniversityRecruiting
- Westchester Medical Center
- Randolph HospitalRecruiting
- Hope Women's Cancer Centers-AshevilleRecruiting
- Cone Health Cancer Center at Alamance RegionalRecruiting
- UNC Lineberger Comprehensive Cancer CenterRecruiting
- Carolinas Medical Center/Levine Cancer Institute
- Novant Health Presbyterian Medical CenterRecruiting
- Oncology Specialists of CharlotteRecruiting
- Southern Oncology Specialists-CharlotteRecruiting
- Carolinas HealthCare System NorthEast
- Duke University Medical CenterRecruiting
- Cone Health Cancer CenterRecruiting
- Lake Norman Hematology Oncology Specialists-HuntersvilleRecruiting
- Presbyterian Hospital HuntersvilleRecruiting
- Southern Oncology Specialists-HuntersvilleRecruiting
- Novant Health Oncology Specialists-KernersvilleRecruiting
- Novant Health Cancer Specialists-MatthewsRecruiting
- Cone Heath Cancer Center at MebaneRecruiting
- Lake Norman Hematology Oncology Specialists-MooresvilleRecruiting
- Novant Health Oncology Specialists-Mount AiryRecruiting
- FirstHealth of the Carolinas-Moore Regional HospitalRecruiting
- Annie Penn Memorial HospitalRecruiting
- Novant Health Oncology Specialists-Statesville
- Novant Health Oncology Specialists-Davidson CountyRecruiting
- Novant Health Oncology Specialists-WilkesboroRecruiting
- New Hanover Regional Medical Center/Zimmer Cancer Center
- Novant Health Forsyth Medical CenterRecruiting
- Novant Health Oncology SpecialistsRecruiting
- Winston-Salem Health Care
- Sanford Bismarck Medical CenterRecruiting
- Roger Maris Cancer CenterRecruiting
- Sanford Broadway Medical CenterRecruiting
- Sanford Clinic North-FargoRecruiting
- Strecker Cancer Center-BelpreRecruiting
- Aultman Health FoundationRecruiting
- Adena Regional Medical CenterRecruiting
- Good Samaritan Hospital - CincinnatiRecruiting
- Bethesda North HospitalRecruiting
- TriHealth Cancer Institute-WestsideRecruiting
- TriHealth Cancer Institute-AndersonRecruiting
- Case Western Reserve University
- MetroHealth Medical Center
- Cleveland Clinic Cancer Center/Fairview HospitalRecruiting
- Cleveland Clinic FoundationRecruiting
- Ohio State University Comprehensive Cancer CenterRecruiting
- Mount Carmel East HospitalRecruiting
- Columbus Oncology and Hematology Associates IncRecruiting
- Riverside Methodist HospitalRecruiting
- Grant Medical CenterRecruiting
- The Mark H Zangmeister CenterRecruiting
- Mount Carmel Health Center WestRecruiting
- Doctors HospitalRecruiting
- Delaware Health Center-Grady Cancer CenterRecruiting
- Delaware Radiation OncologyRecruiting
- Grady Memorial HospitalRecruiting
- Fairfield Medical CenterRecruiting
- OhioHealth Mansfield HospitalRecruiting
- Marietta Memorial HospitalRecruiting
- OhioHealth Marion General HospitalRecruiting
- Hillcrest Hospital Cancer CenterRecruiting
- Lake University Ireland Cancer Center
- Knox Community HospitalRecruiting
- Licking Memorial HospitalRecruiting
- Newark Radiation OncologyRecruiting
- Southern Ohio Medical CenterRecruiting
- Flower Hospital
- University of Toledo
- Saint Ann's HospitalRecruiting
- Genesis Healthcare System Cancer Care CenterRecruiting
- University of Oklahoma Health Sciences CenterRecruiting
- Oklahoma Cancer Specialists and Research Institute-TulsaRecruiting
- Saint Alphonsus Medical Center-Baker CityRecruiting
- Saint Charles Health SystemRecruiting
- Clackamas Radiation Oncology CenterRecruiting
- Providence Oncology and Hematology Care SoutheastRecruiting
- Bay Area HospitalRecruiting
- Providence Newberg Medical CenterRecruiting
- Saint Alphonsus Medical Center-OntarioRecruiting
- Providence Willamette Falls Medical Center
- Providence Portland Medical CenterRecruiting
- Providence Saint Vincent Medical CenterRecruiting
- Abington Memorial HospitalRecruiting
- Lehigh Valley Hospital-Cedar CrestRecruiting
- Saint Luke's University Hospital-Bethlehem CampusRecruiting
- Lehigh Valley Hospital - MuhlenbergRecruiting
- Geisinger Medical CenterRecruiting
- Adams Cancer CenterRecruiting
- Geisinger Medical Center-Cancer Center HazletonRecruiting
- Forbes HospitalRecruiting
- Allegheny Valley HospitalRecruiting
- University of Pennsylvania/Abramson Cancer CenterRecruiting
- Pennsylvania HospitalRecruiting
- West Penn HospitalRecruiting
- University of Pittsburgh Cancer Institute (UPCI)Recruiting
- Community Medical CenterRecruiting
- Geisinger Medical GroupRecruiting
- Chester County HospitalRecruiting
- Wexford Health and Wellness PavilionRecruiting
- Geisinger Wyoming Valley/Henry Cancer CenterRecruiting
- WellSpan Health-York HospitalRecruiting
- Women and Infants HospitalRecruiting
- Medical University of South CarolinaRecruiting
- Greenville Health System Cancer Institute-EasleyRecruiting
- Gibbs Cancer Center-GaffneyRecruiting
- Greenville Health System Cancer Institute-ButternutRecruiting
- Greenville Health System Cancer Institute-FarisRecruiting
- Greenville Health System Cancer Institute-EastsideRecruiting
- Self Regional Healthcare
- Greenville Health System Cancer Institute-GreerRecruiting
- Gibbs Cancer Center-PelhamRecruiting
- Greenville Health System Cancer Institute-SenecaRecruiting
- Spartanburg Medical CenterRecruiting
- Greenville Health System Cancer Institute-SpartanburgRecruiting
- Sanford Cancer Center Oncology ClinicRecruiting
- Sanford USD Medical Center - Sioux FallsRecruiting
- Chattanooga's Program in Women's Oncology
- Memorial HospitalRecruiting
- Pulmonary Medicine Center of Chattanooga-HixsonRecruiting
- University of Tennessee - KnoxvilleRecruiting
- Saint Thomas Midtown HospitalRecruiting
- Memorial GYN PlusRecruiting
- Saint Joseph Regional Cancer CenterRecruiting
- Parkland Memorial Hospital
- UT Southwestern/Simmons Cancer Center-Dallas
- Brooke Army Medical CenterRecruiting
- Baylor All Saints Medical Center at Fort Worth
- Lyndon Baines Johnson General Hospital
- M D Anderson Cancer CenterRecruiting
- Memorial Hermann Texas Medical Center
- The Methodist Hospital SystemRecruiting
- Methodist Willowbrook HospitalRecruiting
- Houston Methodist Sugar Land HospitalRecruiting
- American Fork Hospital / Huntsman Intermountain Cancer CenterRecruiting
- Sandra L Maxwell Cancer CenterRecruiting
- Farmington Health CenterRecruiting
- Logan Regional HospitalRecruiting
- Intermountain Medical CenterRecruiting
- McKay-Dee Hospital CenterRecruiting
- Utah Valley Regional Medical CenterRecruiting
- Dixie Medical Center Regional Cancer CenterRecruiting
- Utah Cancer Specialists-Salt Lake CityRecruiting
- Huntsman Cancer Institute/University of UtahRecruiting
- LDS HospitalRecruiting
- South Jordan Health Center
- University of Vermont Medical Center
- University of Virginia Cancer CenterRecruiting
- Naval Medical Center - PortsmouthRecruiting
- Henrico Doctor's Hospital
- Virginia Gynecologic Oncology
- Virginia Commonwealth University/Massey Cancer CenterRecruiting
- Carilion Clinic Gynecological OncologyRecruiting
- Providence Regional Cancer System-AberdeenRecruiting
- MultiCare Auburn Medical CenterRecruiting
- Virginia Mason Bainbridge Island Medical CenterRecruiting
- Overlake Hospital Medical CenterRecruiting
- PeaceHealth Saint Joseph Medical CenterRecruiting
- Harrison HealthPartners Hematology and Oncology-Bremerton
- Harrison Medical Center
- Highline Medical Center-Main CampusRecruiting
- Providence Regional Cancer System-CentraliaRecruiting
- Swedish Medical Center-EdmondsRecruiting
- Saint Elizabeth HospitalRecruiting
- Providence Regional Cancer PartnershipRecruiting
- Virginia Mason Federal Way Medical CenterRecruiting
- Saint Francis HospitalRecruiting
- Tacoma/Valley Radiation Oncology Centers-Gig HarborRecruiting
- MultiCare Gig Harbor Medical ParkRecruiting
- Swedish Cancer Institute-IssaquahRecruiting
- Kadlec Clinic Hematology and OncologyRecruiting
- Northwest Cancer Clinic
- Providence Regional Cancer System-LaceyRecruiting
- Saint Clare HospitalRecruiting
- PeaceHealth Saint John Medical CenterRecruiting
- Virginia Mason Lynnwood Medical CenterRecruiting
- Skagit Valley Hospital Regional Cancer Care CenterRecruiting
- Skagit Valley HospitalRecruiting
- Jefferson HealthcareRecruiting
- Harrison HealthPartners Hematology and Oncology-Poulsbo
- Peninsula Cancer CenterRecruiting
- MultiCare Good Samaritan HospitalRecruiting
- Tacoma/Valley Radiation Oncology Centers-PuyallupRecruiting
- Virginia Mason Medical CenterRecruiting
- Pacific Gynecology SpecialistsRecruiting
- Swedish Medical Center-Ballard CampusRecruiting
- Fred Hutchinson Cancer Research CenterRecruiting
- Seattle Cancer Care AllianceRecruiting
- Kaiser Permanente WashingtonRecruiting
- Swedish Medical Center-First HillRecruiting
- Swedish Medical Center-Cherry HillRecruiting
- Northwest HospitalRecruiting
- Women's Cancer Center of SeattleRecruiting
- University of Washington Medical CenterRecruiting
- Providence Regional Cancer System-SheltonRecruiting
- Rockwood Clinic Cancer Treatment Center-ValleyRecruiting
- Rockwood Cancer Treatment Center-DHEC-DowntownRecruiting
- Spokane Valley Cancer Center-MayfairRecruiting
- Spokane Valley Cancer Center-MissionRecruiting
- Rockwood North Cancer Treatment CenterRecruiting
- Tacoma/Valley Radiation Oncology Centers-Jackson HallRecruiting
- Franciscan Research Center-Northwest Medical PlazaRecruiting
- MultiCare Tacoma General HospitalRecruiting
- Northwest Medical Specialties PLLCRecruiting
- Northwest NCI Community Oncology Research ProgramRecruiting
- Tacoma/Valley Radiation Oncology Centers-Saint Joe'sRecruiting
- PeaceHealth Southwest Medical CenterRecruiting
- Providence Saint Mary Regional Cancer CenterRecruiting
- Wenatchee Valley Hospital and ClinicsRecruiting
- Providence Regional Cancer System-YelmRecruiting
- Monongalia HospitalRecruiting
- Aurora Cancer Care-Southern Lakes VLCCRecruiting
- Marshfield Clinic-Chippewa CenterRecruiting
- Marshfield Clinic Cancer Center - Eau ClaireRecruiting
- Marshfield Clinic Cancer Center at Sacred Heart
- Aurora Health Center-Fond du LacRecruiting
- Aurora Health Care Germantown Health CenterRecruiting
- Aurora Cancer Care-GraftonRecruiting
- Green Bay Oncology at Saint Vincent HospitalRecruiting
- Saint Vincent Hospital Cancer Center Green BayRecruiting
- Green Bay Oncology Limited at Saint Mary's HospitalRecruiting
- Saint Vincent Hospital Cancer Center at Saint Mary'sRecruiting
- Aurora BayCare Medical CenterRecruiting
- Aurora Cancer Care-Kenosha SouthRecruiting
- Gundersen Lutheran Medical CenterRecruiting
- Marshfield Clinic - Ladysmith CenterRecruiting
- University of Wisconsin Hospital and ClinicsRecruiting
- Holy Family Memorial HospitalRecruiting
- Aurora Bay Area Medical Group-MarinetteRecruiting
- Bay Area Medical Center
- Vince Lombardi Cancer Clinic-MarinetteRecruiting
- Marshfield ClinicRecruiting
- Aurora Cancer Care-MilwaukeeRecruiting
- Aurora Saint Luke's Medical CenterRecruiting
- Froedtert and the Medical College of WisconsinRecruiting
- Aurora Sinai Medical CenterRecruiting
- Marshfield Clinic-Minocqua CenterRecruiting
- Cancer Center of Western WisconsinRecruiting
- Vince Lombardi Cancer Clinic - OshkoshRecruiting
- Aurora Cancer Care-RacineRecruiting
- Ascension Saint Mary's Hospital
- Marshfield Clinic-Rice Lake CenterRecruiting
- Vince Lombardi Cancer Clinic-SheboyganRecruiting
- Ascension Saint Michael's Hospital
- Marshfield Clinic Stevens Point CenterRecruiting
- Aurora Medical Center in SummitRecruiting
- Vince Lombardi Cancer Clinic-Two RiversRecruiting
- Aurora Cancer Care-Waukesha
- Marshfield Clinic-Wausau CenterRecruiting
- Aurora Cancer Care-Milwaukee WestRecruiting
- Aurora West Allis Medical CenterRecruiting
- Marshfield Clinic - Weston CenterRecruiting
- Marshfield Clinic - Wisconsin Rapids CenterRecruiting
- Rocky Mountain Oncology
- Cheyenne Regional Medical Center-WestRecruiting
- Big Horn Basin Cancer Center
- Billings Clinic-CodyRecruiting
- Welch Cancer Center
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Group I (lifestyle intervention)
Group II (observation)
Participants receive a dietary intervention designed to promote increased levels of plasma carotenoids, control weight, and to ensure adequacy of micronutrient intake. Participants also undergo a physical activity intervention comprising a moderately low aerobic regimen to raise the usual activity level. Participants also undergo face-to-face counseling, receive educational materials and counseling focused on how to read food labels to estimate grams of fat per serving and serving size, and undergo telephone counseling by a lifestyle intervention counselor twice a week for 4 weeks, then weekly for 2 weeks, twice a month for 5 months, monthly for the subsequent 6 months, and then once every other month for 12 months. Participants complete daily fat gram and step diaries at least three times per week.
Participants receive a study notebook containing general study-related information. Participants are not asked to record diet or physical activity but are provided a single sample diary in their study notebook. Participants receive telephone contact on a sliding scale similar to the intervention group, but at less frequent intervals (22 versus 33 calls over the course of the intervention).