Adventure: Teacher Delivered Personality-targeted Interventions for Substance Misuse (Adventure)
Primary Purpose
Alcohol Abuse, Drug Abuse, Depression
Status
Completed
Phase
Phase 2
Locations
United Kingdom
Study Type
Interventional
Intervention
Personality-targeted interventions
Sponsored by
About this trial
This is an interventional prevention trial for Alcohol Abuse
Eligibility Criteria
Inclusion Criteria:
- Secondary school student
Exclusion Criteria:
- None
Sites / Locations
- Institute of Psychiatry, King's College London
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm Type
Experimental
Experimental
Experimental
Experimental
Arm Label
learning to cope with your impulsivity
learning to cope with your sensation seeking
learning to cope with your anxiety sensitivity
learning to manage your negative thinking
Arm Description
Cognitive-behavioural intervention targeting impulsive personality
cognitive behavioural intervention designed to help sensation seeking youth manage their need for stimulation and excitement.
cognitive behavioural intervention teaching anxiety sensitive youth to manager their sensitivity to threat and anxiety.
cognitive behavioural intervention targeting pessimistic and negative thinking in hopeless youth
Outcomes
Primary Outcome Measures
Binge drinking frequency
Frequency in the past 6 months that subject reported drinking 5 or more alcoholic beverages (4 or more for girls) on one drinking occasion.
Drinking frequency
Past six months frequency of drinking
drinking quantity
Average number of alcoholic beverages consumed on a typical drinking occasion in the past six months
Drinking problems
number of drinking problems reported on an abbreviated version of the Rutger's Alcohol Problem Index.
illicit drug use events
Time to onset of illicit drug use
Secondary Outcome Measures
Emotional and behavioural problems, targeted and school-wide effects
Psychiatric symptoms (depression, panic anxiety, antisocial behaviours), coping skills, motives for drinking, school attendance and attainment, in-class behaviours assessed using the Strengths and Difficulties Questionnaire and the Brief Symptom Inventory.
Full Information
NCT ID
NCT00776685
First Posted
October 17, 2008
Last Updated
June 24, 2011
Sponsor
King's College London
Collaborators
Action on Addiction
1. Study Identification
Unique Protocol Identification Number
NCT00776685
Brief Title
Adventure: Teacher Delivered Personality-targeted Interventions for Substance Misuse
Acronym
Adventure
Official Title
Cognitive Behavioral Interventions That Target Personality Risk for Substance Abuse and Mental Illness: Delivery by Educational Professionals
Study Type
Interventional
2. Study Status
Record Verification Date
December 2010
Overall Recruitment Status
Completed
Study Start Date
May 2007 (undefined)
Primary Completion Date
March 2010 (Actual)
Study Completion Date
May 2010 (Actual)
3. Sponsor/Collaborators
Name of the Sponsor
King's College London
Collaborators
Action on Addiction
4. Oversight
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
Several personality factors have been shown to be associated with risk for alcohol and substance misuse, and differentiate substance abusers based on clinical profile, treatment response and susceptibility to other forms of mental illness. Personality-targeted interventions have been found to have significant preventative effects on onset and growth of drinking, binge-drinking and drinking problems in adolescents attending mainstream schools (Conrod, Castellanos & Mackie, 2008). The interventions concurrently reduced personality-specific emotional and behavioural problems (Castellanos & Conrod, 2006), and prevented the onset and escalation of drug-use over a two-year period (Conrod, Castellanos-Ryan & Strang, 2010). This cluster randomised controlled trial aims to examine whether these results can be replicated when interventions are delivered by trained educational professionals. In addition, the trial will evaluate the broader impact of the programme on cigarette smoking, school attendance, academic achievement and school-wide behaviours.
Detailed Description
The Adventure study aims to examine whether educational professionals such as teachers, mentors or individuals in a pastoral role, who are trained in carrying out personality-targeted interventions will be effective in reducing problem behaviours in a group of adolescents.
20 schools in London, U.K. were recruited for the trial, and over 2000 adolescents (mean age 13.7 years) consented to participate in the survey and intervention phases of the trial. Schools were randomly assigned to control or intervention condition, and students in intervention schools who met the criteria for any of the 4 personality risk subscales of the Substance Use Risk Profile Scale (Negative Thinking, Anxiety Sensitivity, Sensation Seeking and Impulsivity) were invited to participate in a personality-targeted intervention by trained members of staff from their schools. All participants were invited to complete follow-up surveys at 6-month intervals for 2 years. The remaining 55% of low risk students in the grad were also followed to examine population-level effects of the intervention as well.
The main outcome measures of this RCT are alcohol and illicit drug outcomes. Secondary measures include mental health symptoms, risky behaviour, school attainment and attendance, and school-wide behaviours.
It is hypothesised that teacher-delivered personality-targeted interventions will have similar preventative effects on alcohol and drug use as reported by Conrod et al (2008, 2010), in addition to the personality-specific intervention effects reported by Castellanos & Conrod (2006). In addition, broader effects of the intervention on academic achievement and school-wide behaviour will be examined in this trial, both at the individual level and at the population-level.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Alcohol Abuse, Drug Abuse, Depression, Panic Disorder, Conduct Disorder
7. Study Design
Primary Purpose
Prevention
Study Phase
Phase 2, Phase 3
Interventional Study Model
Factorial Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
3190 (Actual)
8. Arms, Groups, and Interventions
Arm Title
learning to cope with your impulsivity
Arm Type
Experimental
Arm Description
Cognitive-behavioural intervention targeting impulsive personality
Arm Title
learning to cope with your sensation seeking
Arm Type
Experimental
Arm Description
cognitive behavioural intervention designed to help sensation seeking youth manage their need for stimulation and excitement.
Arm Title
learning to cope with your anxiety sensitivity
Arm Type
Experimental
Arm Description
cognitive behavioural intervention teaching anxiety sensitive youth to manager their sensitivity to threat and anxiety.
Arm Title
learning to manage your negative thinking
Arm Type
Experimental
Arm Description
cognitive behavioural intervention targeting pessimistic and negative thinking in hopeless youth
Intervention Type
Behavioral
Intervention Name(s)
Personality-targeted interventions
Other Intervention Name(s)
Preventure, but now delivered by teachers
Intervention Description
Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained teacher and co-facilitator
Primary Outcome Measure Information:
Title
Binge drinking frequency
Description
Frequency in the past 6 months that subject reported drinking 5 or more alcoholic beverages (4 or more for girls) on one drinking occasion.
Time Frame
2 years
Title
Drinking frequency
Description
Past six months frequency of drinking
Time Frame
2 years
Title
drinking quantity
Description
Average number of alcoholic beverages consumed on a typical drinking occasion in the past six months
Time Frame
2 years
Title
Drinking problems
Description
number of drinking problems reported on an abbreviated version of the Rutger's Alcohol Problem Index.
Time Frame
2 years
Title
illicit drug use events
Description
Time to onset of illicit drug use
Time Frame
2 years
Secondary Outcome Measure Information:
Title
Emotional and behavioural problems, targeted and school-wide effects
Description
Psychiatric symptoms (depression, panic anxiety, antisocial behaviours), coping skills, motives for drinking, school attendance and attainment, in-class behaviours assessed using the Strengths and Difficulties Questionnaire and the Brief Symptom Inventory.
Time Frame
2 years
10. Eligibility
Sex
All
Minimum Age & Unit of Time
13 Years
Maximum Age & Unit of Time
16 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
Secondary school student
Exclusion Criteria:
None
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Patricia J Conrod, PhD
Organizational Affiliation
King's College London
Official's Role
Study Chair
Facility Information:
Facility Name
Institute of Psychiatry, King's College London
City
London
Country
United Kingdom
12. IPD Sharing Statement
Citations:
PubMed Identifier
20048226
Citation
Conrod PJ, Castellanos-Ryan N, Strang J. Brief, personality-targeted coping skills interventions and survival as a non-drug user over a 2-year period during adolescence. Arch Gen Psychiatry. 2010 Jan;67(1):85-93. doi: 10.1001/archgenpsychiatry.2009.173.
Results Reference
background
PubMed Identifier
18211277
Citation
Conrod PJ, Castellanos N, Mackie C. Personality-targeted interventions delay the growth of adolescent drinking and binge drinking. J Child Psychol Psychiatry. 2008 Feb;49(2):181-90. doi: 10.1111/j.1469-7610.2007.01826.x.
Results Reference
background
PubMed Identifier
17007600
Citation
Conrod PJ, Stewart SH, Comeau N, Maclean AM. Efficacy of cognitive-behavioral interventions targeting personality risk factors for youth alcohol misuse. J Clin Child Adolesc Psychol. 2006 Dec;35(4):550-63. doi: 10.1207/s15374424jccp3504_6.
Results Reference
background
PubMed Identifier
20732631
Citation
O'Leary-Barrett M, Mackie CJ, Castellanos-Ryan N, Al-Khudhairy N, Conrod PJ. Personality-targeted interventions delay uptake of drinking and decrease risk of alcohol-related problems when delivered by teachers. J Am Acad Child Adolesc Psychiatry. 2010 Sep;49(9):954-963.e1. doi: 10.1016/j.jaac.2010.04.011. Epub 2010 Jul 31.
Results Reference
result
PubMed Identifier
26881449
Citation
O'Leary-Barrett M, Castellanos-Ryan N, Pihl RO, Conrod PJ. Mechanisms of personality-targeted intervention effects on adolescent alcohol misuse, internalizing and externalizing symptoms. J Consult Clin Psychol. 2016 May;84(5):438-52. doi: 10.1037/ccp0000082. Epub 2016 Feb 15.
Results Reference
derived
PubMed Identifier
26011508
Citation
Mahu IT, Doucet C, O'Leary-Barrett M, Conrod PJ. Can cannabis use be prevented by targeting personality risk in schools? Twenty-four-month outcome of the adventure trial on cannabis use: a cluster-randomized controlled trial. Addiction. 2015 Oct;110(10):1625-33. doi: 10.1111/add.12991. Epub 2015 Jul 14.
Results Reference
derived
PubMed Identifier
23344135
Citation
Conrod PJ, O'Leary-Barrett M, Newton N, Topper L, Castellanos-Ryan N, Mackie C, Girard A. Effectiveness of a selective, personality-targeted prevention program for adolescent alcohol use and misuse: a cluster randomized controlled trial. JAMA Psychiatry. 2013 Mar;70(3):334-42. doi: 10.1001/jamapsychiatry.2013.651.
Results Reference
derived
Learn more about this trial
Adventure: Teacher Delivered Personality-targeted Interventions for Substance Misuse
We'll reach out to this number within 24 hrs