Supplements and Social Skills Intervention Study (SASSI)
Conduct Disorder, Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder
About this trial
This is an interventional treatment trial for Conduct Disorder focused on measuring Attention Deficit Hyperactivity Disorder, Conduct Disorder, Oppositional Defiant Disorder, Omega 3 Supplements, Social Skills Training, Dietary Intake, Aggression, Nutrition, Disruptive Behaviors Disorder
Eligibility Criteria
Inclusion Criteria:
- Subjects between ages 7 and 16 years
- Subjects who fulfils all criteria for a DSM-IV diagnosis of ADHD, conduct disorder, or oppositional defiant disorder
- Subjects with willingness to participate in a randomized, double-blind controlled trial,
- Subjects with complete with written, informed parental consent and assent
- Subjects with IQ of 70 or more
Exclusion Criteria:
- Subjects who have IQ in the below 70
- Subjects who are younger than 7 years old
- Those without written parental consent will not be allowed to participate in the study
- Those with brain pathology such as serious head injury, epilepsy will be excluded
Sites / Locations
- Child Guidance Clinic, Health Promotion Board, Institute of Mental Health
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Experimental
Experimental
Placebo Comparator
1
2
3
4
Omega-3 + Standard treatment Children in this group will be given 400 mg of DHA and 600 mg of EPA. Caregivers will be instructed to give two 500mg Omega-3 capsules twice a day, at breakfast and at the evening meal for 6 months. Parents will be seen by the attending on a monthly basis for standard treatment procedure.
Social skills + Omega-3 placebo + Standard treatment Children in this group will be given two placebo capsules twice daily; at breakfast and at the evening meal for a total period of 6 months. They will also undergo a manualised group social problem solving skills training protocol of 12 weekly 1-hour sessions (Ang & Ooi, 2003a, 2003b). There will be booster sessions scheduled at 3-week intervals after the initial treatment period of 12 weeks, for a total of 4 booster sessions.
Omega-3 + Social skills + Standard treatment Children in this group will receive omega-3 supplement and social skills training on top of standard treatment. Procedures for administration of Omega-3 supplement are similar to those stated in (1) and (2).
Omega-3 placebo + Standard treatment. Children in this group will receive placebo as well as a course of the standard treatment. Procedure for administering the placebo capsules is similar to that outlined in (2).