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Efficacy and Safety of Aliskiren and Aliskiren/Enalapril Combination on Morbidity-mortality in Patients With Chronic Heart Failure (ATMOSPHERE)

Primary Purpose

Chronic Heart Failure

Status

Completed

Phase

Phase 3

Locations

International

Study Type

Interventional

Intervention

Enalapril

Aliskiren

About this trial

This is an interventional treatment trial for Chronic Heart Failure focused on measuring Chronic Heart Failure, Cardiovascular death, CHF hospitalization, morbi-mortality trial, outcome study, endpoint driven, plasma renin activity, renin angiotensin aldosterone system, direct renin inhibitors, BNP, KCCQ, eGFR, (NYHA class II to IV) with elevated, BNP and reduced LVEF

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria

Patients eligible for inclusion in this study had to fulfill all of the following criteria:

Patients ≥ 18 years of age, male or female.
Patients with a diagnosis of chronic heart failure (NYHA
Class II - IV):
1. LVEF ≤ 35% at Visit 1 (local measurement, within the past 6 months assessed by echocardiography, multiple uptake gated acquisition scan (MUGA), computerized tomography(CT) scan, magnetic resonance imaging (MRI) or ventricular angiography)
2. Elevated BNP or NT-proBNP at Visit 1:
BNP ≥ 150 pg/mL (or BNP ≥ 100 pg/mL and unplanned hospitalization for HF within the last 12 months prior to Visit 1) (according to local measurement). OR NT-proBNP ≥ 600 pg/mL (or NT-proBNP ≥ 400 pg/mL and unplanned hospitalization for HF within the last 12 months prior to Visit 1) (according to local measurement).
Patients had to be treated with an ACEI at a stable dose enalapril 10 mg daily at least or any other ACEI, e.g. ramipril, quinapril, lisinopril, fosinopril, perindopril, trandolapril; based on equivalent doses, for at least 4 weeks prior to Visit 1
Patients had to be treated with a beta-blocker, unless contraindicated or not tolerated, at a stable dose for at least 4 weeks prior to visit 1 (for patients not on target dose, according to local guidelines, or in absence of that medication, the reason should be documented).
Written informed consent to participate in the study and ability to comply with all requirements.

Exclusion Criteria

Patients with any of the following were to be excluded from participation in the study:

History of hypersensitivity to any of the study drugs including history or allergy to ACEIs as well as known or suspected contraindications to the study drugs or previous history of intolerance to high doses of ACEIs during up- titration process.
Patients treated concomitantly with both an ARB and an aldosterone antagonist in addition to study drug at Visit 1.
Current acute decompensated HF (defined as an acute exacerbation of a chronic heart failure status manifested by typical signs and symptoms of HF like dyspnea, fatigue etc., that may require IV therapy with diuretics, vasodilators and/or inotropic drugs).
Symptomatic hypotension and/or less than 95 mmHg systolic blood pressure (SBP) at Visit 1 and/or less than 90 mmHg SBP at Visit 4.
Acute coronary syndrome, stroke, transient ischemic attack, cardiac, carotid or major vascular surgery, percutaneous coronary intervention (PCI) or carotid angioplasty, within the past 3 months prior to Visit 1.
Coronary or carotid artery disease likely to require surgical or percutaneous intervention within the 6 months after Visit 1.
Right heart failure due to severe pulmonary disease.
Patients with Diabetes Mellitus.

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm Type

Experimental

Active Comparator

Arm Label

Combination Aliskiren / Enalapril

Aliskiren

Enalapril

Arm Description

Aliskiren / Enalapril combination therapy-150 mg/10 mg titrated to 300 mg/ 10 mg film-coated tablets and administered orally.

Aliskiren monotherapy - 150 mg titrated to 300 mg film-coated tablets and administered orally.

Enalapril monotherapy -10 mg film-coated tablet and administered orally.

Outcomes

Primary Outcome Measures

Number of Participants That Had First Occurrence of the Composite Endpoint, Which is Defined as Either Cardiovascular (CV) Death or Heart Failure (HF) Hospitalization

Number of participants that had first occurrence of the composite endpoint, which is defined as either CV death or HF hospitalization due to HF.

Secondary Outcome Measures

Change From Baseline to Month 12 for the Kansas City Cardiomyopathy Questionnaire (KCCQ) Clinical Summary Score

Change from baseline to Month 12 for the Kansas City Cardiomyopathy Questionnaire (KCCQ) clinical summary score. KCCQ is a 23-item, self-administered instrument that quantifies physical function, symptoms (frequency, severity and recent change), social function, self-efficacy and knowledge, and quality of life. KCCQ clinical summary score is a composite assessment of physical limitations and total symptom scores. Scores are transformed to a range of 0-100, in which higher scores reflect better health status.

All Cause Death

Number of patients - All-cause death. All-cause death is common in Heart Failure HF patients this measures how many patients had this event.

Full Information

NCT ID

NCT00853658

First Posted

February 26, 2009

Last Updated

October 3, 2016

Sponsor

Novartis Pharmaceuticals

1. Study Identification

Unique Protocol Identification Number

NCT00853658

Brief Title

Efficacy and Safety of Aliskiren and Aliskiren/Enalapril Combination on Morbidity-mortality in Patients With Chronic Heart Failure

Acronym

ATMOSPHERE

Official Title

A Multicenter, Randomized, Double-blind, Parallel Group, Active-controlled Study to Evaluate the Efficacy and Safety of Both Aliskiren Monotherapy and Aliskiren/Enalapril Combination Therapy Compared to Enalapril Monotherapy, on Morbidity and Mortality in Patients With Chronic Heart Failure (NYHA Class II - IV). The Study is Also Known as Aliskiren Trial of Minimizing OutcomeS in Patients With HEart Failure (ATMOSPHERE).

Study Type

Interventional

2. Study Status

Record Verification Date

October 2016

Overall Recruitment Status

Completed

Study Start Date

March 2009 (undefined)

Primary Completion Date

October 2015 (Actual)

Study Completion Date

October 2015 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title

Sponsor

Name of the Sponsor

Novartis Pharmaceuticals

4. Oversight

Data Monitoring Committee

Yes

5. Study Description

Brief Summary

The study will evaluate the efficacy and safety of both aliskiren monotherapy and aliskiren/enalapril combination therapy as compared to enalapril monotherapy, on morbidity and mortality in patients with chronic heart failure (NYHA Class II - IV.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study

Chronic Heart Failure

Keywords

Chronic Heart Failure, Cardiovascular death, CHF hospitalization, morbi-mortality trial, outcome study, endpoint driven, plasma renin activity, renin angiotensin aldosterone system, direct renin inhibitors, BNP, KCCQ, eGFR, (NYHA class II to IV) with elevated, BNP and reduced LVEF

7. Study Design

Primary Purpose

Treatment

Study Phase

Phase 3

Interventional Study Model

Parallel Assignment

Masking

ParticipantCare ProviderInvestigator

Allocation

Randomized

Enrollment

7064 (Actual)

8. Arms, Groups, and Interventions

Arm Title

Combination Aliskiren / Enalapril

Arm Type

Experimental

Arm Description

Aliskiren / Enalapril combination therapy-150 mg/10 mg titrated to 300 mg/ 10 mg film-coated tablets and administered orally.

Arm Title

Aliskiren

Arm Type

Experimental

Arm Description

Aliskiren monotherapy - 150 mg titrated to 300 mg film-coated tablets and administered orally.

Arm Title

Enalapril

Arm Type

Active Comparator

Arm Description

Enalapril monotherapy -10 mg film-coated tablet and administered orally.

Intervention Type

Drug

Intervention Name(s)

Enalapril

Intervention Description

Enalapril 10 mg film-coated tablet and administered orally.

Intervention Type

Drug

Intervention Name(s)

Aliskiren

Other Intervention Name(s)

SPP100

Intervention Description

Aliskiren 150 mg titrated to 300 mg film-coated tablet and administered orally.

Primary Outcome Measure Information:

Title

Number of Participants That Had First Occurrence of the Composite Endpoint, Which is Defined as Either Cardiovascular (CV) Death or Heart Failure (HF) Hospitalization

Description

Number of participants that had first occurrence of the composite endpoint, which is defined as either CV death or HF hospitalization due to HF.

Time Frame

up to End of Study (78 months)

Secondary Outcome Measure Information:

Title

Change From Baseline to Month 12 for the Kansas City Cardiomyopathy Questionnaire (KCCQ) Clinical Summary Score

Description

Time Frame

Baseline, Month 12

Title

All Cause Death

Description

Number of patients - All-cause death. All-cause death is common in Heart Failure HF patients this measures how many patients had this event.

Time Frame

up to end of study (78 months)

10. Eligibility

Sex

All

Minimum Age & Unit of Time

18 Years

Accepts Healthy Volunteers

Eligibility Criteria

Inclusion Criteria Patients eligible for inclusion in this study had to fulfill all of the following criteria: Patients ≥ 18 years of age, male or female. Patients with a diagnosis of chronic heart failure (NYHA Class II - IV): LVEF ≤ 35% at Visit 1 (local measurement, within the past 6 months assessed by echocardiography, multiple uptake gated acquisition scan (MUGA), computerized tomography(CT) scan, magnetic resonance imaging (MRI) or ventricular angiography) Elevated BNP or NT-proBNP at Visit 1: BNP ≥ 150 pg/mL (or BNP ≥ 100 pg/mL and unplanned hospitalization for HF within the last 12 months prior to Visit 1) (according to local measurement). OR NT-proBNP ≥ 600 pg/mL (or NT-proBNP ≥ 400 pg/mL and unplanned hospitalization for HF within the last 12 months prior to Visit 1) (according to local measurement). Patients had to be treated with an ACEI at a stable dose enalapril 10 mg daily at least or any other ACEI, e.g. ramipril, quinapril, lisinopril, fosinopril, perindopril, trandolapril; based on equivalent doses, for at least 4 weeks prior to Visit 1 Patients had to be treated with a beta-blocker, unless contraindicated or not tolerated, at a stable dose for at least 4 weeks prior to visit 1 (for patients not on target dose, according to local guidelines, or in absence of that medication, the reason should be documented). Written informed consent to participate in the study and ability to comply with all requirements. Exclusion Criteria Patients with any of the following were to be excluded from participation in the study: History of hypersensitivity to any of the study drugs including history or allergy to ACEIs as well as known or suspected contraindications to the study drugs or previous history of intolerance to high doses of ACEIs during up- titration process. Patients treated concomitantly with both an ARB and an aldosterone antagonist in addition to study drug at Visit 1. Current acute decompensated HF (defined as an acute exacerbation of a chronic heart failure status manifested by typical signs and symptoms of HF like dyspnea, fatigue etc., that may require IV therapy with diuretics, vasodilators and/or inotropic drugs). Symptomatic hypotension and/or less than 95 mmHg systolic blood pressure (SBP) at Visit 1 and/or less than 90 mmHg SBP at Visit 4. Acute coronary syndrome, stroke, transient ischemic attack, cardiac, carotid or major vascular surgery, percutaneous coronary intervention (PCI) or carotid angioplasty, within the past 3 months prior to Visit 1. Coronary or carotid artery disease likely to require surgical or percutaneous intervention within the 6 months after Visit 1. Right heart failure due to severe pulmonary disease. Patients with Diabetes Mellitus.

Overall Study Officials:

First Name & Middle Initial & Last Name & Degree

Novartis Pharmaceuticals

Organizational Affiliation

Novartis Pharmaceuticals

Official's Role

Study Director

Facility Information:

Facility Name

Novartis Investigative Site

City

Huntsville

State/Province

Alabama

ZIP/Postal Code

35801

Country

United States

Facility Name

Novartis Investigative Site

City

Mobile

State/Province

Alabama

ZIP/Postal Code

36608

Country

United States

Facility Name

Novartis Investigative Site

City

Mobile

State/Province

Alabama

ZIP/Postal Code

36693

Country

United States

Facility Name

Novartis Investigative Site

City

Tucson

State/Province

Arizona

ZIP/Postal Code

85723-0001

Country

United States

Facility Name

Novartis Investigative Site

City

Hot Springs

State/Province

Arkansas

ZIP/Postal Code

71913

Country

United States

Facility Name

Novartis Investigative Site

City

Little Rock

State/Province

Arkansas

ZIP/Postal Code

72204

Country

United States

Facility Name

Novartis Investigative Site

City

Little Rock

State/Province

Arkansas

ZIP/Postal Code

72205

Country

United States

Facility Name

Novartis Investigative Site

City

Pine Bluff

State/Province

Arkansas

ZIP/Postal Code

71603

Country

United States

Facility Name

Novartis Investigative Site

City

Searcy

State/Province

Arkansas

ZIP/Postal Code

72143

Country

United States

Facility Name

Novartis Investigative Site

City

Beverly Hills

State/Province

California

ZIP/Postal Code

90211

Country

United States

Facility Name

Novartis Investigative Site

City

French Camp

State/Province

California

ZIP/Postal Code

95231

Country

United States

Facility Name

Novartis Investigative Site

City

Inglewood

State/Province

California

ZIP/Postal Code

90301

Country

United States

Facility Name

Novartis Investigative Site

City

Los Angeles

State/Province

California

ZIP/Postal Code

90073

Country

United States

Facility Name

Novartis Investigative Site

City

Modesto

State/Province

California

ZIP/Postal Code

95355

Country

United States

Facility Name

Novartis Investigative Site

City

Northridge

State/Province

California

ZIP/Postal Code

91325

Country

United States

Facility Name

Novartis Investigative Site

City

Sacramento

State/Province

California

ZIP/Postal Code

95825

Country

United States

Facility Name

Novartis Investigative Site

City

San Diego

State/Province

California

ZIP/Postal Code

92123

Country

United States

Facility Name

Novartis Investigative Site

City

Santa Monica

State/Province

California

ZIP/Postal Code

90404

Country

United States

Facility Name

Novartis Investigative Site

City

Westlake Village

State/Province

California

ZIP/Postal Code

91361

Country

United States

Facility Name

Novartis Investigative Site

City

Denver

State/Province

Colorado

ZIP/Postal Code

80218

Country

United States

Facility Name

Novartis Investigative Site

City

Littleton

State/Province

Colorado

ZIP/Postal Code

80120

Country

United States

Facility Name

Novartis Investigative Site

City

Boynton Beach

State/Province

Florida

ZIP/Postal Code

33437

Country

United States

Facility Name

Novartis Investigative Site

City

Daytona Beach

State/Province

Florida

ZIP/Postal Code

32117

Country

United States

Facility Name

Novartis Investigative Site

City

Fort Lauderdale

State/Province

Florida

ZIP/Postal Code

33316

Country

United States

Facility Name

Novartis Investigative Site

City

Hollywood

State/Province

Florida

ZIP/Postal Code

33021

Country

United States

Facility Name

Novartis Investigative Site

City

Jacksonville Beach

State/Province

Florida

ZIP/Postal Code

32050

Country

United States

Facility Name

Novartis Investigative Site

City

Miami Lakes

State/Province

Florida

ZIP/Postal Code

33014

Country

United States

Facility Name

Novartis Investigative Site

City

Orlando

State/Province

Florida

ZIP/Postal Code

32803

Country

United States

Facility Name

Novartis Investigative Site

City

Wellington

State/Province

Florida

ZIP/Postal Code

33449

Country

United States

Facility Name

Novartis Investigative Site

City

Athens

State/Province

Georgia

ZIP/Postal Code

30606

Country

United States

Facility Name

Novartis Investigative Site

City

Augusta

State/Province

Georgia

ZIP/Postal Code

30904

Country

United States

Facility Name

Novartis Investigative Site

City

Gillespie

State/Province

Illinois

ZIP/Postal Code

62033

Country

United States

Facility Name

Novartis Investigative Site

City

Topeka

State/Province

Kansas

ZIP/Postal Code

66606

Country

United States

Facility Name

Novartis Investigative Site

City

Metairie

State/Province

Louisiana

ZIP/Postal Code

70006

Country

United States

Facility Name

Novartis Investigative Site

City

New Orleans

State/Province

Louisiana

ZIP/Postal Code

70121

Country

United States

Facility Name

Novartis Investigative Site

City

Slidell

State/Province

Louisiana

ZIP/Postal Code

70458

Country

United States

Facility Name

Novartis Investigative Site

City

Auburn

State/Province

Maine

ZIP/Postal Code

04210

Country

United States

Facility Name

Novartis Investigative Site

City

Southfield

State/Province

Michigan

ZIP/Postal Code

48075

Country

United States

Facility Name

Novartis Investigative Site

City

St. Louis

State/Province

Missouri

ZIP/Postal Code

63110

Country

United States

Facility Name

Novartis Investigative Site

City

Lincoln

State/Province

Nebraska

ZIP/Postal Code

68506

Country

United States

Facility Name

Novartis Investigative Site

City

Omaha

State/Province

Nebraska

ZIP/Postal Code

68198

Country

United States

Facility Name

Novartis Investigative Site

City

Elmer

State/Province

New Jersey

ZIP/Postal Code

08318

Country

United States

Facility Name

Novartis Investigative Site

City

Laurelton

State/Province

New York

ZIP/Postal Code

11422

Country

United States

Facility Name

Novartis Investigative Site

City

Stony Brook

State/Province

New York

ZIP/Postal Code

11794

Country

United States

Facility Name

Novartis Investigative Site

City

Wiliamsville

State/Province

New York

ZIP/Postal Code

14221

Country

United States

Facility Name

Novartis Investigative Site

City

Durham

State/Province

North Carolina

ZIP/Postal Code

27710

Country

United States

Facility Name

Novartis Investigative Site

City

Marion

State/Province

Ohio

ZIP/Postal Code

43302

Country

United States

Facility Name

Novartis Investigative Site

City

Charleston

State/Province

South Carolina

ZIP/Postal Code

29403

Country

United States

Facility Name

Novartis Investigative Site

City

Varnville

State/Province

South Carolina

ZIP/Postal Code

29944

Country

United States

Facility Name

Novartis Investigative Site

City

Germantown

State/Province

Tennessee

ZIP/Postal Code

38138

Country

United States

Facility Name

Novartis Investigative Site

City

Memphis

State/Province

Tennessee

ZIP/Postal Code

38120

Country

United States

Facility Name

Novartis Investigative Site

City

Nashville

State/Province

Tennessee

ZIP/Postal Code

37205

Country

United States

Facility Name

Novartis Investigative Site

City

Nashville

State/Province

Tennessee

ZIP/Postal Code

37212

Country

United States

Facility Name

Novartis Investigative Site

City

Dallas

State/Province

Texas

ZIP/Postal Code

75226

Country

United States

Facility Name

Novartis Investigative Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77021

Country

United States

Facility Name

Novartis Investigative Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77030

Country

United States

Facility Name

Novartis Investigative Site

City

Everett

State/Province

Washington

ZIP/Postal Code

98208

Country

United States

Facility Name

Novartis Investigative Site

City

Kirkland

State/Province

Washington

ZIP/Postal Code

98034

Country

United States

Facility Name

Novartis Investigative Site

City

Bahia Blanca

State/Province

Buenos Aires

ZIP/Postal Code

8000

Country

Argentina

Facility Name

Novartis Investigative Site

City

Caba

State/Province

Buenos Aires

ZIP/Postal Code

C1180AAX

Country

Argentina

Facility Name

Novartis Investigative Site

City

Caba

State/Province

Buenos Aires

ZIP/Postal Code

C1408INH

Country

Argentina

Facility Name

Novartis Investigative Site

City

Caba

State/Province

Buenos Aires

ZIP/Postal Code

C1416DRJ

Country

Argentina

Facility Name

Novartis Investigative Site

City

Coronel Suarez

State/Province

Buenos Aires

ZIP/Postal Code

B7540GHD

Country

Argentina

Facility Name

Novartis Investigative Site

City

La Plata

State/Province

Buenos Aires

ZIP/Postal Code

1900

Country

Argentina

Facility Name

Novartis Investigative Site

City

Quilmes

State/Province

Buenos Aires

ZIP/Postal Code

B1878GEG

Country

Argentina

Facility Name

Novartis Investigative Site

City

Ramos Mejia

State/Province

Buenos Aires

ZIP/Postal Code

B1704ETD

Country

Argentina

Facility Name

Novartis Investigative Site

City

San Isidro

State/Province

Buenos Aires

ZIP/Postal Code

B1642DCD

Country

Argentina

Facility Name

Novartis Investigative Site

City

San Nicolas

State/Province

Buenos Aires

ZIP/Postal Code

B2900DMH

Country

Argentina

Facility Name

Novartis Investigative Site

City

Córdoba

State/Province

Cordoba

ZIP/Postal Code

X5152HQC

Country

Argentina

Facility Name

Novartis Investigative Site

City

Va Allende

State/Province

Cordoba

ZIP/Postal Code

5105

Country

Argentina

Facility Name

Novartis Investigative Site

City

Villa Maria

State/Province

Cordoba

ZIP/Postal Code

X5220XAO

Country

Argentina

Facility Name

Novartis Investigative Site

City

Posadas

State/Province

Misiones

ZIP/Postal Code

N3300AHX

Country

Argentina

Facility Name

Novartis Investigative Site

City

Tucuman

State/Province

San Miguel de Tucuman

ZIP/Postal Code

T4000ICL

Country

Argentina

Facility Name

Novartis Investigative Site

City

Rosario

State/Province

Santa Fe

ZIP/Postal Code

S2000CXH

Country

Argentina

Facility Name

Novartis Investigative Site

City

Rosario

State/Province

Santa Fe

ZIP/Postal Code

S2000DFD

Country

Argentina

Facility Name

Novartis Investigative Site

City

Rosario

State/Province

Santa Fe

ZIP/Postal Code

S2000DSV

Country

Argentina

Facility Name

Novartis Investigative Site

City

Rosario

State/Province

Santa Fe

ZIP/Postal Code

S2001ODA

Country

Argentina

Facility Name

Novartis Investigative Site

City

San Miguel de Tucuman

State/Province

Tucuman

ZIP/Postal Code

T4000IFL

Country

Argentina

Facility Name

Novartis Investigative Site

City

Buenos Aires

ZIP/Postal Code

C1094AAD

Country

Argentina

Facility Name

Novartis Investigative Site

City

Buenos Aires

ZIP/Postal Code

C1428DCO

Country

Argentina

Facility Name

Novartis Investigative Site

City

Cordoba

ZIP/Postal Code

X5000AAI

Country

Argentina

Facility Name

Novartis Investigative Site

City

Cordoba

ZIP/Postal Code

X5000AVI

Country

Argentina

Facility Name

Novartis Investigative Site

City

Cordoba

ZIP/Postal Code

X5000EPU

Country

Argentina

Facility Name

Novartis Investigative Site

City

Cordoba

ZIP/Postal Code

X5000EVQ

Country

Argentina

Facility Name

Novartis Investigative Site

City

Cordoba

ZIP/Postal Code

X5000FGG

Country

Argentina

Facility Name

Novartis Investigative Site

City

Cordoba

ZIP/Postal Code

X5002AOQ

Country

Argentina

Facility Name

Novartis Investigative Site

City

Cordoba

ZIP/Postal Code

X5003DCE

Country

Argentina

Facility Name

Novartis Investigative Site

City

Cordoba

ZIP/Postal Code

X5004BAL

Country

Argentina

Facility Name

Novartis Investigative Site

City

Cordoba

ZIP/Postal Code

X5006IKK

Country

Argentina

Facility Name

Novartis Investigative Site

City

Cordoba

ZIP/Postal Code

X5009BSN

Country

Argentina

Facility Name

Novartis Investigative Site

City

Cordoba

ZIP/Postal Code

X5022CPU

Country

Argentina

Facility Name

Novartis Investigative Site

City

Cordoba

ZIP/Postal Code

X5220XAO

Country

Argentina

Facility Name

Novartis Investigative Site

City

Corrientes

ZIP/Postal Code

W3400CBI

Country

Argentina

Facility Name

Novartis Investigative Site

City

Corrientes

ZIP/Postal Code

W3400

Country

Argentina

Facility Name

Novartis Investigative Site

City

Salta

ZIP/Postal Code

4400

Country

Argentina

Facility Name

Novartis Investigative Site

City

Canberra

State/Province

Australian Capital Territory

ZIP/Postal Code

2605

Country

Australia

Facility Name

Novartis Investigative Site

City

Darlinghurst

State/Province

New South Wales

ZIP/Postal Code

2010

Country

Australia

Facility Name

Novartis Investigative Site

City

Kingswood

State/Province

New South Wales

ZIP/Postal Code

2747

Country

Australia

Facility Name

Novartis Investigative Site

City

Wollongong

State/Province

New South Wales

ZIP/Postal Code

2500

Country

Australia

Facility Name

Novartis Investigative Site

City

Auchenflower

State/Province

Queensland

ZIP/Postal Code

4066

Country

Australia

Facility Name

Novartis Investigative Site

City

Woolloongabba

State/Province

Queensland

ZIP/Postal Code

4101

Country

Australia

Facility Name

Novartis Investigative Site

City

Wooloongabba

State/Province

Queensland

ZIP/Postal Code

4102

Country

Australia

Facility Name

Novartis Investigative Site

City

Bedford Park

State/Province

South Australia

ZIP/Postal Code

5042

Country

Australia

Facility Name

Novartis Investigative Site

City

Launceston

State/Province

Tasmania

ZIP/Postal Code

7250

Country

Australia

Facility Name

Novartis Investigative Site

City

Geelong

State/Province

Victoria

ZIP/Postal Code

3220

Country

Australia

Facility Name

Novartis Investigative Site

City

Prahran

State/Province

Victoria

ZIP/Postal Code

3181

Country

Australia

Facility Name

Novartis Investigative Site

City

Innsbruck

State/Province

Tyrol

ZIP/Postal Code

6020

Country

Austria

Facility Name

Novartis Investigative Site

City

Graz

ZIP/Postal Code

A-8036

Country

Austria

Facility Name

Novartis Investigative Site

City

Linz

ZIP/Postal Code

4010

Country

Austria

Facility Name

Novartis Investigative Site

City

Linz

ZIP/Postal Code

A-4010

Country

Austria

Facility Name

Novartis Investigative Site

City

Salzburg

ZIP/Postal Code

A-5020

Country

Austria

Facility Name

Novartis Investigative Site

City

Vienna

ZIP/Postal Code

1030

Country

Austria

Facility Name

Novartis Investigative Site

City

Vienna

ZIP/Postal Code

1140

Country

Austria

Facility Name

Novartis Investigative Site

City

Wien

ZIP/Postal Code

A-1090

Country

Austria

Facility Name

Novartis Investigative Site

City

Wien

ZIP/Postal Code

A-1160

Country

Austria

Facility Name

Novartis Investigative Site

City

Anderlecht

ZIP/Postal Code

1070

Country

Belgium

Facility Name

Novartis Investigative Site

City

Brugge

ZIP/Postal Code

8000

Country

Belgium

Facility Name

Novartis Investigative Site

City

Brussels

ZIP/Postal Code

1180

Country

Belgium

Facility Name

Novartis Investigative Site

City

Bruxelles

ZIP/Postal Code

1200

Country

Belgium

Facility Name

Novartis Investigative Site

City

De Pinte

ZIP/Postal Code

9840

Country

Belgium

Facility Name

Novartis Investigative Site

City

Eupen

ZIP/Postal Code

4700

Country

Belgium

Facility Name

Novartis Investigative Site

City

Genk

ZIP/Postal Code

3600

Country

Belgium

Facility Name

Novartis Investigative Site

City

Huy

ZIP/Postal Code

4500

Country

Belgium

Facility Name

Novartis Investigative Site

City

Ieper

ZIP/Postal Code

8900

Country

Belgium

Facility Name

Novartis Investigative Site

City

Leuven

ZIP/Postal Code

3000

Country

Belgium

Facility Name

Novartis Investigative Site

City

Liege

ZIP/Postal Code

4000

Country

Belgium

Facility Name

Novartis Investigative Site

City

Turnhout

ZIP/Postal Code

2300

Country

Belgium

Facility Name

Novartis Investigative Site

City

Fortaleza

State/Province

ZIP/Postal Code

60864-190

Country

Brazil

Facility Name

Novartis Investigative Site

City

Brasilia

State/Province

ZIP/Postal Code

70658-700

Country

Brazil

Facility Name

Novartis Investigative Site

City

Goiania

State/Province

ZIP/Postal Code

74605-050

Country

Brazil

Facility Name

Novartis Investigative Site

City

Belo Horizonte

State/Province

ZIP/Postal Code

30110-934

Country

Brazil

Facility Name

Novartis Investigative Site

City

Belo Horizonte

State/Province

Country

Brazil

Facility Name

Novartis Investigative Site

City

Recife

State/Province

ZIP/Postal Code

50100-060

Country

Brazil

Facility Name

Novartis Investigative Site

City

Campina Grande do Sul

State/Province

ZIP/Postal Code

83430-000

Country

Brazil

Facility Name

Novartis Investigative Site

City

Curitiba

State/Province

ZIP/Postal Code

80010-030

Country

Brazil

Facility Name

Novartis Investigative Site

City

Londrina

State/Province

ZIP/Postal Code

86051-990

Country

Brazil

Facility Name

Novartis Investigative Site

City

Rio de Janeiro

State/Province

ZIP/Postal Code

22240-006

Country

Brazil

Facility Name

Novartis Investigative Site

City

Caxias do Sul

State/Province

ZIP/Postal Code

95070-560

Country

Brazil

Facility Name

Novartis Investigative Site

City

Porto Alegre

State/Province

ZIP/Postal Code

90020-090

Country

Brazil

Facility Name

Novartis Investigative Site

City

Porto Alegre

State/Province

ZIP/Postal Code

90035-903

Country

Brazil

Facility Name

Novartis Investigative Site

City

Porto Alegre

State/Province

ZIP/Postal Code

90560-030

Country

Brazil

Facility Name

Novartis Investigative Site

City

Porto Alegre

State/Province

ZIP/Postal Code

90610-000

Country

Brazil

Facility Name

Novartis Investigative Site

City

Campinas

State/Province

ZIP/Postal Code

13020-431

Country

Brazil

Facility Name

Novartis Investigative Site

City

Campinas

State/Province

ZIP/Postal Code

13060-904

Country

Brazil

Facility Name

Novartis Investigative Site

City

Campinas

State/Province

ZIP/Postal Code

13083-190

Country

Brazil

Facility Name

Novartis Investigative Site

City

Marilia

State/Province

ZIP/Postal Code

17519-030

Country

Brazil

Facility Name

Novartis Investigative Site

City

São Paulo

State/Province

ZIP/Postal Code

05403-900

Country

Brazil

Facility Name

Novartis Investigative Site

City

Tatuí

State/Province

ZIP/Postal Code

18270-170

Country

Brazil

Facility Name

Novartis Investigative Site

City

Calgary

State/Province

Alberta

ZIP/Postal Code

T2N 4Z6

Country

Canada

Facility Name

Novartis Investigative Site

City

St. John

State/Province

New Brunswick

ZIP/Postal Code

E2L 4L2

Country

Canada

Facility Name

Novartis Investigative Site

City

Brampton

State/Province

Ontario

ZIP/Postal Code

L6Z 4N5

Country

Canada

Facility Name

Novartis Investigative Site

City

Cambridge

State/Province

Ontario

ZIP/Postal Code

N1R 6V6

Country

Canada

Facility Name

Novartis Investigative Site

City

Ottawa

State/Province

Ontario

ZIP/Postal Code

K1Y 4W7

Country

Canada

Facility Name

Novartis Investigative Site

City

Joliette

State/Province

Quebec

ZIP/Postal Code

J6E 6J2

Country

Canada

Facility Name

Novartis Investigative Site

City

Montreal

State/Province

Quebec

ZIP/Postal Code

H1T 1C8

Country

Canada

Facility Name

Novartis Investigative Site

City

Montreal

State/Province

Quebec

ZIP/Postal Code

H1T 3Y7

Country

Canada

Facility Name

Novartis Investigative Site

City

Québec

State/Province

Quebec

ZIP/Postal Code

G1J 1Z6

Country

Canada

Facility Name

Novartis Investigative Site

City

Sainte-Foy

State/Province

Quebec

ZIP/Postal Code

G1V 4G5

Country

Canada

Facility Name

Novartis Investigative Site

City

Beijing

State/Province

Beijing

ZIP/Postal Code

100083

Country

China

Facility Name

Novartis Investigative Site

City

Beijing

State/Province

Beijing

ZIP/Postal Code

100088

Country

China

Facility Name

Novartis Investigative Site

City

Beijing

State/Province

Beijing

ZIP/Postal Code

100730

Country

China

Facility Name

Novartis Investigative Site

City

Fuzhou

State/Province

Fujian

ZIP/Postal Code

350001

Country

China

Facility Name

Novartis Investigative Site

City

Guangzhou

State/Province

Guangdong

ZIP/Postal Code

510080

Country

China

Facility Name

Novartis Investigative Site

City

Guangzhou

State/Province

Guangdong

ZIP/Postal Code

510515

Country

China

Facility Name

Novartis Investigative Site

City

Shijiazhuang

State/Province

Hebei

ZIP/Postal Code

050000

Country

China

Facility Name

Novartis Investigative Site

City

Wuhan

State/Province

Hubei

ZIP/Postal Code

430022

Country

China

Facility Name

Novartis Investigative Site

City

Nanjing

State/Province

Jiangsu

Country

China

Facility Name

Novartis Investigative Site

City

Suzhou

State/Province

Jiangsu

ZIP/Postal Code

215004

Country

China

Facility Name

Novartis Investigative Site

City

Changchun

State/Province

Jilin

ZIP/Postal Code

130021

Country

China

Facility Name

Novartis Investigative Site

City

Shenyang

State/Province

Liaoning

ZIP/Postal Code

110003

Country

China

Facility Name

Novartis Investigative Site

City

Shenyang

State/Province

Liaoning

ZIP/Postal Code

110016

Country

China

Facility Name

Novartis Investigative Site

City

Shanghai

State/Province

Shanghai

ZIP/Postal Code

200011

Country

China

Facility Name

Novartis Investigative Site

City

Tianjin

State/Province

Tianjin

ZIP/Postal Code

300121

Country

China

Facility Name

Novartis Investigative Site

City

Hangzhou

State/Province

Zhejiang

ZIP/Postal Code

310006

Country

China

Facility Name

Novartis Investigative Site

City

Hangzhou

State/Province

Zhejiang

ZIP/Postal Code

310009

Country

China

Facility Name

Novartis Investigative Site

City

Hangzhou

State/Province

Zhejiang

ZIP/Postal Code

310013

Country

China

Facility Name

Novartis Investigative Site

City

Hangzhou

State/Province

Zhejiang

ZIP/Postal Code

310016

Country

China

Facility Name

Novartis Investigative Site

City

Baotou

ZIP/Postal Code

014040

Country

China

Facility Name

Novartis Investigative Site

City

Beijing

ZIP/Postal Code

100020

Country

China

Facility Name

Novartis Investigative Site

City

Beijing

ZIP/Postal Code

100028

Country

China

Facility Name

Novartis Investigative Site

City

Beijing

ZIP/Postal Code

100029

Country

China

Facility Name

Novartis Investigative Site

City

Beijing

ZIP/Postal Code

100034

Country

China

Facility Name

Novartis Investigative Site

City

Beijing

ZIP/Postal Code

100044

Country

China

Facility Name

Novartis Investigative Site

City

Beijing

ZIP/Postal Code

100050

Country

China

Facility Name

Novartis Investigative Site

City

Guang zhou

ZIP/Postal Code

510080

Country

China

Facility Name

Novartis Investigative Site

City

Jinan

ZIP/Postal Code

250012

Country

China

Facility Name

Novartis Investigative Site

City

Shanghai

ZIP/Postal Code

200025

Country

China

Facility Name

Novartis Investigative Site

City

Shanghai

ZIP/Postal Code

200032

Country

China

Facility Name

Novartis Investigative Site

City

Shanghai

ZIP/Postal Code

200233

Country

China

Facility Name

Novartis Investigative Site

City

Tianjin

ZIP/Postal Code

300142

Country

China

Facility Name

Novartis Investigative Site

City

Xian

ZIP/Postal Code

710004

Country

China

Facility Name

Novartis Investigative Site

City

Medellín

State/Province

Antioquia

Country

Colombia

Facility Name

Novartis Investigative Site

City

Baranquilla

State/Province

Atlantico

Country

Colombia

Facility Name

Novartis Investigative Site

City

Barranquilla

State/Province

Atlantico

Country

Colombia

Facility Name

Novartis Investigative Site

City

Cartagena

State/Province

Bolivar

Country

Colombia

Facility Name

Novartis Investigative Site

City

Bogota

State/Province

Cundinamarca

ZIP/Postal Code

111411

Country

Colombia

Facility Name

Novartis Investigative Site

City

Bogotá

State/Province

Cundinamarca

ZIP/Postal Code

110111

Country

Colombia

Facility Name

Novartis Investigative Site

City

Barranquilla

Country

Colombia

Facility Name

Novartis Investigative Site

City

Bogotá

ZIP/Postal Code

00000

Country

Colombia

Facility Name

Novartis Investigative Site

City

Bogotá

Country

Colombia

Facility Name

Novartis Investigative Site

City

Florida Blanca

Country

Colombia

Facility Name

Novartis Investigative Site

City

Medellín

Country

Colombia

Facility Name

Novartis Investigative Site

City

Goicoechea

State/Province

San Jose, Costa Rica

ZIP/Postal Code

3184-1000

Country

Costa Rica

Facility Name

Novartis Investigative Site

City

Alajuela

Country

Costa Rica

Facility Name

Novartis Investigative Site

City

San Jose

ZIP/Postal Code

1307-1000

Country

Costa Rica

Facility Name

Novartis Investigative Site

City

San Jose

ZIP/Postal Code

272-1225

Country

Costa Rica

Facility Name

Novartis Investigative Site

City

Benesov

ZIP/Postal Code

25601

Country

Czech Republic

Facility Name

Novartis Investigative Site

City

Brno

ZIP/Postal Code

60200

Country

Czech Republic

Facility Name

Novartis Investigative Site

City

Cesky Krumlov

ZIP/Postal Code

381 01

Country

Czech Republic

Facility Name

Novartis Investigative Site

City

Jindrichuv Hradec

ZIP/Postal Code

377 01

Country

Czech Republic

Facility Name

Novartis Investigative Site

City

Kolín

ZIP/Postal Code

280 02

Country

Czech Republic

Facility Name

Novartis Investigative Site

City

Kromeriz

ZIP/Postal Code

767 01

Country

Czech Republic

Facility Name

Novartis Investigative Site

City

Louny

ZIP/Postal Code

440 01

Country

Czech Republic

Facility Name

Novartis Investigative Site

City

Louny

Country

Czech Republic

Facility Name

Novartis Investigative Site

City

Marianske lazne

ZIP/Postal Code

353 01

Country

Czech Republic

Facility Name

Novartis Investigative Site

City

Ostrava

ZIP/Postal Code

70200

Country

Czech Republic

Facility Name

Novartis Investigative Site

City

Plzen

ZIP/Postal Code

323 00

Country

Czech Republic

Facility Name

Novartis Investigative Site

City

Praha 11

ZIP/Postal Code

148 00

Country

Czech Republic

Facility Name

Novartis Investigative Site

City

Praha 2

ZIP/Postal Code

128 08

Country

Czech Republic

Facility Name

Novartis Investigative Site

City

Praha 9

Country

Czech Republic

Facility Name

Novartis Investigative Site

City

Pribram VIII

ZIP/Postal Code

261 01

Country

Czech Republic

Facility Name

Novartis Investigative Site

City

Teplice

ZIP/Postal Code

415 01

Country

Czech Republic

Facility Name

Novartis Investigative Site

City

Vyskov

ZIP/Postal Code

68001

Country

Czech Republic

Facility Name

Novartis Investigative Site

City

Aalborg

ZIP/Postal Code

DK-9000

Country

Denmark

Facility Name

Novartis Investigative Site

City

Copenhagen NV

ZIP/Postal Code

DK-2400

Country

Denmark

Facility Name

Novartis Investigative Site

City

Copenhagen S

ZIP/Postal Code

DK-2300

Country

Denmark

Facility Name

Novartis Investigative Site

City

Copenhagen

ZIP/Postal Code

2100

Country

Denmark

Facility Name

Novartis Investigative Site

City

Esbjerg

ZIP/Postal Code

DK-6700

Country

Denmark

Facility Name

Novartis Investigative Site

City

Fredericia

ZIP/Postal Code

7000

Country

Denmark

Facility Name

Novartis Investigative Site

City

Frederiksberg

ZIP/Postal Code

DK-2000

Country

Denmark

Facility Name

Novartis Investigative Site

City

Glostrup

ZIP/Postal Code

DK-2600

Country

Denmark

Facility Name

Novartis Investigative Site

City

Hellerup

ZIP/Postal Code

DK-2900

Country

Denmark

Facility Name

Novartis Investigative Site

City

Helsingoer

ZIP/Postal Code

DK-3000

Country

Denmark

Facility Name

Novartis Investigative Site

City

Hillerød

ZIP/Postal Code

DK-3400

Country

Denmark

Facility Name

Novartis Investigative Site

City

Hjørring

ZIP/Postal Code

DK-9800

Country

Denmark

Facility Name

Novartis Investigative Site

City

Holbæk

ZIP/Postal Code

DK-4300

Country

Denmark

Facility Name

Novartis Investigative Site

City

Hvidovre

ZIP/Postal Code

DK-2650

Country

Denmark

Facility Name

Novartis Investigative Site

City

Køge

ZIP/Postal Code

DK-4600

Country

Denmark

Facility Name

Novartis Investigative Site

City

Næstved

ZIP/Postal Code

DK-4700

Country

Denmark

Facility Name

Novartis Investigative Site

City

Odense C

ZIP/Postal Code

DK-5000

Country

Denmark

Facility Name

Novartis Investigative Site

City

Randers NØ

ZIP/Postal Code

DK-8930

Country

Denmark

Facility Name

Novartis Investigative Site

City

Silkeborg

ZIP/Postal Code

8600

Country

Denmark

Facility Name

Novartis Investigative Site

City

Svendborg

ZIP/Postal Code

DK-5700

Country

Denmark

Facility Name

Novartis Investigative Site

City

Viborg

ZIP/Postal Code

DK-8800

Country

Denmark

Facility Name

Novartis Investigative Site

City

Århus N

ZIP/Postal Code

DK-8200

Country

Denmark

Facility Name

Novartis Investigative Site

City

Santo Domingo

State/Province

Republica Dominicana

Country

Dominican Republic

Facility Name

Novartis Investigative Site

City

San Cristobal

Country

Dominican Republic

Facility Name

Novartis Investigative Site

City

Parnu

ZIP/Postal Code

80010

Country

Estonia

Facility Name

Novartis Investigative Site

City

Tallinn

ZIP/Postal Code

10138

Country

Estonia

Facility Name

Novartis Investigative Site

City

Tallinn

ZIP/Postal Code

13419

Country

Estonia

Facility Name

Novartis Investigative Site

City

Tartu

ZIP/Postal Code

51014

Country

Estonia

Facility Name

Novartis Investigative Site

City

Hyvinkää

ZIP/Postal Code

FIN-05850

Country

Finland

Facility Name

Novartis Investigative Site

City

Jyvaskyla

ZIP/Postal Code

FIN-40620

Country

Finland

Facility Name

Novartis Investigative Site

City

Seinajoki

ZIP/Postal Code

60200

Country

Finland

Facility Name

Novartis Investigative Site

City

Tammisaari

ZIP/Postal Code

10600

Country

Finland

Facility Name

Novartis Investigative Site

City

Turku

ZIP/Postal Code

FIN-20520

Country

Finland

Facility Name

Novartis Investigative Site

City

Albi

ZIP/Postal Code

81013

Country

France

Facility Name

Novartis Investigative Site

City

Angers

ZIP/Postal Code

49000

Country

France

Facility Name

Novartis Investigative Site

City

Becon Les Granits

ZIP/Postal Code

49370

Country

France

Facility Name

Novartis Investigative Site

City

Clichy

ZIP/Postal Code

92110

Country

France

Facility Name

Novartis Investigative Site

City

Dijon

ZIP/Postal Code

21079

Country

France

Facility Name

Novartis Investigative Site

City

Grenoble

ZIP/Postal Code

38043

Country

France

Facility Name

Novartis Investigative Site

City

Marseille Cedex 05

ZIP/Postal Code

13385

Country

France

Facility Name

Novartis Investigative Site

City

Marseille

ZIP/Postal Code

13915

Country

France

Facility Name

Novartis Investigative Site

City

Paris

ZIP/Postal Code

75013

Country

France

Facility Name

Novartis Investigative Site

City

Paris

ZIP/Postal Code

75571

Country

France

Facility Name

Novartis Investigative Site

City

Pessac Cedex

ZIP/Postal Code

33604

Country

France

Facility Name

Novartis Investigative Site

City

Saint-Etienne

ZIP/Postal Code

42055

Country

France

Facility Name

Novartis Investigative Site

City

Vandoeuvre Les Nancy

ZIP/Postal Code

54511

Country

France

Facility Name

Novartis Investigative Site

City

Winsen (Luhe)

State/Province

Lower Saxony

ZIP/Postal Code

21423

Country

Germany

Facility Name

Novartis Investigative Site

City

Augsburg

ZIP/Postal Code

86150

Country

Germany

Facility Name

Novartis Investigative Site

City

Bad Nauheim

ZIP/Postal Code

61231

Country

Germany

Facility Name

Novartis Investigative Site

City

Bad Neustadt an der Saale

ZIP/Postal Code

97616

Country

Germany

Facility Name

Novartis Investigative Site

City

Bensheim

ZIP/Postal Code

64625

Country

Germany

Facility Name

Novartis Investigative Site

City

Berlin

ZIP/Postal Code

10367

Country

Germany

Facility Name

Novartis Investigative Site

City

Berlin

ZIP/Postal Code

10789

Country

Germany

Facility Name

Novartis Investigative Site

City

Berlin

ZIP/Postal Code

12163

Country

Germany

Facility Name

Novartis Investigative Site

City

Berlin

ZIP/Postal Code

12351

Country

Germany

Facility Name

Novartis Investigative Site

City

Berlin

ZIP/Postal Code

12552

Country

Germany

Facility Name

Novartis Investigative Site

City

Berlin

ZIP/Postal Code

13353

Country

Germany

Facility Name

Novartis Investigative Site

City

Berlin

ZIP/Postal Code

13405

Country

Germany

Facility Name

Novartis Investigative Site

City

Bochum

ZIP/Postal Code

44791

Country

Germany

Facility Name

Novartis Investigative Site

City

Bonn

ZIP/Postal Code

53115

Country

Germany

Facility Name

Novartis Investigative Site

City

Bonn

ZIP/Postal Code

53127

Country

Germany

Facility Name

Novartis Investigative Site

City

Bonn

ZIP/Postal Code

53225

Country

Germany

Facility Name

Novartis Investigative Site

City

Brake

ZIP/Postal Code

26919

Country

Germany

Facility Name

Novartis Investigative Site

City

Celle

ZIP/Postal Code

29223

Country

Germany

Facility Name

Novartis Investigative Site

City

Chemnitz

ZIP/Postal Code

09113

Country

Germany

Facility Name

Novartis Investigative Site

City

Chemnitz

ZIP/Postal Code

09116

Country

Germany

Facility Name

Novartis Investigative Site

City

Chemnitz

ZIP/Postal Code

09126

Country

Germany

Facility Name

Novartis Investigative Site

City

Coburg

ZIP/Postal Code

96450

Country

Germany

Facility Name

Novartis Investigative Site

City

Darmstadt

ZIP/Postal Code

64283

Country

Germany

Facility Name

Novartis Investigative Site

City

Dessau-Roßlau

ZIP/Postal Code

06846

Country

Germany

Facility Name

Novartis Investigative Site

City

Dinkelsbühl

ZIP/Postal Code

91550

Country

Germany

Facility Name

Novartis Investigative Site

City

Dorsten

ZIP/Postal Code

46282

Country

Germany

Facility Name

Novartis Investigative Site

City

Dortmund

ZIP/Postal Code

44137

Country

Germany

Facility Name

Novartis Investigative Site

City

Dresden

ZIP/Postal Code

01067

Country

Germany

Facility Name

Novartis Investigative Site

City

Dresden

ZIP/Postal Code

01097

Country

Germany

Facility Name

Novartis Investigative Site

City

Dresden

ZIP/Postal Code

01219

Country

Germany

Facility Name

Novartis Investigative Site

City

Dresden

ZIP/Postal Code

01277

Country

Germany

Facility Name

Novartis Investigative Site

City

Dresden

ZIP/Postal Code

01309

Country

Germany

Facility Name

Novartis Investigative Site

City

Duisburg

ZIP/Postal Code

47051

Country

Germany

Facility Name

Novartis Investigative Site

City

Duisburg

ZIP/Postal Code

47139

Country

Germany

Facility Name

Novartis Investigative Site

City

Düsseldorf

ZIP/Postal Code

40593

Country

Germany

Facility Name

Novartis Investigative Site

City

Ebersbach

ZIP/Postal Code

02730

Country

Germany

Facility Name

Novartis Investigative Site

City

Erfurt

ZIP/Postal Code

99084

Country

Germany

Facility Name

Novartis Investigative Site

City

Erkner

ZIP/Postal Code

15537

Country

Germany

Facility Name

Novartis Investigative Site

City

Essen

ZIP/Postal Code

45136

Country

Germany

Facility Name

Novartis Investigative Site

City

Essen

ZIP/Postal Code

45355

Country

Germany

Facility Name

Novartis Investigative Site

City

Frankfurt

ZIP/Postal Code

60594

Country

Germany

Facility Name

Novartis Investigative Site

City

Goettingen

ZIP/Postal Code

37075

Country

Germany

Facility Name

Novartis Investigative Site

City

Gotha

ZIP/Postal Code

99867

Country

Germany

Facility Name

Novartis Investigative Site

City

Göttingen

ZIP/Postal Code

37073

Country

Germany

Facility Name

Novartis Investigative Site

City

Gütersloh

ZIP/Postal Code

33332

Country

Germany

Facility Name

Novartis Investigative Site

City

Halle (Saale)

ZIP/Postal Code

06120

Country

Germany

Facility Name

Novartis Investigative Site

City

Halle/Saale

ZIP/Postal Code

06120

Country

Germany

Facility Name

Novartis Investigative Site

City

Hamburg

ZIP/Postal Code

20099

Country

Germany

Facility Name

Novartis Investigative Site

City

Hannover

ZIP/Postal Code

30167

Country

Germany

Facility Name

Novartis Investigative Site

City

Hassloch

ZIP/Postal Code

67454

Country

Germany

Facility Name

Novartis Investigative Site

City

Heidelberg

ZIP/Postal Code

69115

Country

Germany

Facility Name

Novartis Investigative Site

City

Heidelberg

ZIP/Postal Code

69120

Country

Germany

Facility Name

Novartis Investigative Site

City

Heilbronn

ZIP/Postal Code

74078

Country

Germany

Facility Name

Novartis Investigative Site

City

Helmbrechts

ZIP/Postal Code

95223

Country

Germany

Facility Name

Novartis Investigative Site

City

Heppenheim

ZIP/Postal Code

64646

Country

Germany

Facility Name

Novartis Investigative Site

City

Kassel

ZIP/Postal Code

34127

Country

Germany

Facility Name

Novartis Investigative Site

City

Kleve

ZIP/Postal Code

47533

Country

Germany

Facility Name

Novartis Investigative Site

City

Koblenz

ZIP/Postal Code

56068

Country

Germany

Facility Name

Novartis Investigative Site

City

Krefeld

ZIP/Postal Code

47798

Country

Germany

Facility Name

Novartis Investigative Site

City

Köln

ZIP/Postal Code

51605

Country

Germany

Facility Name

Novartis Investigative Site

City

Königsbrück

ZIP/Postal Code

01436

Country

Germany

Facility Name

Novartis Investigative Site

City

Köthen

ZIP/Postal Code

06366

Country

Germany

Facility Name

Novartis Investigative Site

City

Lambrecht

ZIP/Postal Code

67466

Country

Germany

Facility Name

Novartis Investigative Site

City

Landshut

ZIP/Postal Code

84034

Country

Germany

Facility Name

Novartis Investigative Site

City

Leipzig

ZIP/Postal Code

04177

Country

Germany

Facility Name

Novartis Investigative Site

City

Lichtentanne

ZIP/Postal Code

08115

Country

Germany

Facility Name

Novartis Investigative Site

City

Lienen

ZIP/Postal Code

49536

Country

Germany

Facility Name

Novartis Investigative Site

City

Ludwigsburg

ZIP/Postal Code

71634

Country

Germany

Facility Name

Novartis Investigative Site

City

Lörrach

ZIP/Postal Code

79539

Country

Germany

Facility Name

Novartis Investigative Site

City

Lüneburg

ZIP/Postal Code

21339

Country

Germany

Facility Name

Novartis Investigative Site

City

Magdeburg

ZIP/Postal Code

39110

Country

Germany

Facility Name

Novartis Investigative Site

City

Mainz

ZIP/Postal Code

55116

Country

Germany

Facility Name

Novartis Investigative Site

City

Markkleeberg

ZIP/Postal Code

04416

Country

Germany

Facility Name

Novartis Investigative Site

City

Mayen

ZIP/Postal Code

56727

Country

Germany

Facility Name

Novartis Investigative Site

City

Melsungen

ZIP/Postal Code

34212

Country

Germany

Facility Name

Novartis Investigative Site

City

Muehldorf am Inn

ZIP/Postal Code

84453

Country

Germany

Facility Name

Novartis Investigative Site

City

Muehlheim an der Ruhr

ZIP/Postal Code

45468

Country

Germany

Facility Name

Novartis Investigative Site

City

Muenchen

ZIP/Postal Code

80636

Country

Germany

Facility Name

Novartis Investigative Site

City

Mülheim

ZIP/Postal Code

45468

Country

Germany

Facility Name

Novartis Investigative Site

City

Northeim

ZIP/Postal Code

37154

Country

Germany

Facility Name

Novartis Investigative Site

City

Nürnberg

ZIP/Postal Code

90471

Country

Germany

Facility Name

Novartis Investigative Site

City

Oelde

ZIP/Postal Code

59302

Country

Germany

Facility Name

Novartis Investigative Site

City

Oelde

ZIP/Postal Code

59303

Country

Germany

Facility Name

Novartis Investigative Site

City

Pirna

ZIP/Postal Code

01796

Country

Germany

Facility Name

Novartis Investigative Site

City

Potsdam

ZIP/Postal Code

14471

Country

Germany

Facility Name

Novartis Investigative Site

City

Reinfeld

ZIP/Postal Code

23858

Country

Germany

Facility Name

Novartis Investigative Site

City

Salzwedel

ZIP/Postal Code

29410

Country

Germany

Facility Name

Novartis Investigative Site

City

Schwalmstadt

ZIP/Postal Code

34613

Country

Germany

Facility Name

Novartis Investigative Site

City

Schwäbisch Hall

ZIP/Postal Code

74523

Country

Germany

Facility Name

Novartis Investigative Site

City

Siegen

ZIP/Postal Code

57072

Country

Germany

Facility Name

Novartis Investigative Site

City

Solingen

ZIP/Postal Code

42651

Country

Germany

Facility Name

Novartis Investigative Site

City

Stade

ZIP/Postal Code

21682

Country

Germany

Facility Name

Novartis Investigative Site

City

Stuttgart

ZIP/Postal Code

70372

Country

Germany

Facility Name

Novartis Investigative Site

City

Stuttgart

ZIP/Postal Code

70378

Country

Germany

Facility Name

Novartis Investigative Site

City

Wedel

ZIP/Postal Code

22880

Country

Germany

Facility Name

Novartis Investigative Site

City

Witten

ZIP/Postal Code

58455

Country

Germany

Facility Name

Novartis Investigative Site

City

Wuerzburg

ZIP/Postal Code

97078

Country

Germany

Facility Name

Novartis Investigative Site

City

Zwickau

ZIP/Postal Code

08056

Country

Germany

Facility Name

Novartis Investigative Site

City

Athens

State/Province

ZIP/Postal Code

115 27

Country

Greece

Facility Name

Novartis Investigative Site

City

Thessaloniki

State/Province

ZIP/Postal Code

546 36

Country

Greece

Facility Name

Novartis Investigative Site

City

Thessaloniki

State/Province

ZIP/Postal Code

570 10

Country

Greece

Facility Name

Novartis Investigative Site

City

Athens

ZIP/Postal Code

115 28

Country

Greece

Facility Name

Novartis Investigative Site

City

Athens

ZIP/Postal Code

124 62

Country

Greece

Facility Name

Novartis Investigative Site

City

Athens

ZIP/Postal Code

GR 11527

Country

Greece

Facility Name

Novartis Investigative Site

City

Chios

ZIP/Postal Code

82100

Country

Greece

Facility Name

Novartis Investigative Site

City

Edessa

ZIP/Postal Code

58200

Country

Greece

Facility Name

Novartis Investigative Site

City

Guntur

State/Province

Andhra Pradesh

ZIP/Postal Code

522001

Country

India

Facility Name

Novartis Investigative Site

City

Hyderabad

State/Province

Andhra Pradesh

ZIP/Postal Code

500012

Country

India

Facility Name

Novartis Investigative Site

City

Secunderabad

State/Province

Andhra Pradesh

ZIP/Postal Code

500003

Country

India

Facility Name

Novartis Investigative Site

City

Vijayawada

State/Province

Andhra Pradesh

ZIP/Postal Code

520 008

Country

India

Facility Name

Novartis Investigative Site

City

New Delhi

State/Province

Delhi

ZIP/Postal Code

110060

Country

India

Facility Name

Novartis Investigative Site

City

Ahmedabad

State/Province

Gujarat

ZIP/Postal Code

380 051

Country

India

Facility Name

Novartis Investigative Site

City

Bangalore

State/Province

Karnataka

ZIP/Postal Code

560 052

Country

India

Facility Name

Novartis Investigative Site

City

Bangalore

State/Province

Karnataka

ZIP/Postal Code

560099

Country

India

Facility Name

Novartis Investigative Site

City

Manipal

State/Province

Karnataka

ZIP/Postal Code

576104

Country

India

Facility Name

Novartis Investigative Site

City

Trivandrum

State/Province

Kerela

ZIP/Postal Code

695002

Country

India

Facility Name

Novartis Investigative Site

City

Mumbai

State/Province

Maharashtra

ZIP/Postal Code

400 022

Country

India

Facility Name

Novartis Investigative Site

City

Nagpur

State/Province

Maharashtra

ZIP/Postal Code

400 008

Country

India

Facility Name

Novartis Investigative Site

City

Nagpur

State/Province

Maharashtra

ZIP/Postal Code

400 012

Country

India

Facility Name

Novartis Investigative Site

City

Nagpur

State/Province

Maharashtra

ZIP/Postal Code

400012

Country

India

Facility Name

Novartis Investigative Site

City

Nagpur

State/Province

Maharashtra

ZIP/Postal Code

440 010

Country

India

Facility Name

Novartis Investigative Site

City

Nagpur

State/Province

Maharashtra

ZIP/Postal Code

440010

Country

India

Facility Name

Novartis Investigative Site

City

Nagpur

State/Province

Maharashtra

ZIP/Postal Code

440012

Country

India

Facility Name

Novartis Investigative Site

City

Pune

State/Province

Maharashtra

ZIP/Postal Code

411 011

Country

India

Facility Name

Novartis Investigative Site

City

Pune

State/Province

Maharashtra

ZIP/Postal Code

411 019

Country

India

Facility Name

Novartis Investigative Site

City

Pune

State/Province

Maharashtra

ZIP/Postal Code

411 044

Country

India

Facility Name

Novartis Investigative Site

City

Pune

State/Province

Maharashtra

ZIP/Postal Code

411004

Country

India

Facility Name

Novartis Investigative Site

City

Pune

State/Province

Maharashtra

ZIP/Postal Code

411011

Country

India

Facility Name

Novartis Investigative Site

City

Delhi

State/Province

New Delhi

ZIP/Postal Code

110065

Country

India

Facility Name

Novartis Investigative Site

City

Jaipur

State/Province

Rajasthan

ZIP/Postal Code

302001

Country

India

Facility Name

Novartis Investigative Site

City

Jaipur

State/Province

Rajasthan

ZIP/Postal Code

302024

Country

India

Facility Name

Novartis Investigative Site

City

Chennai

State/Province

Tamil Nadu

ZIP/Postal Code

600100

Country

India

Facility Name

Novartis Investigative Site

City

Coimbatore

State/Province

Tamil Nadu

ZIP/Postal Code

641014

Country

India

Facility Name

Novartis Investigative Site

City

Madurai

State/Province

Tamil Nadu

ZIP/Postal Code

625107

Country

India

Facility Name

Novartis Investigative Site

City

Hyderabad

State/Province

Telangana

ZIP/Postal Code

500082

Country

India

Facility Name

Novartis Investigative Site

City

Lucknow

State/Province

Uttar Pradesh

ZIP/Postal Code

226005

Country

India

Facility Name

Novartis Investigative Site

City

Lucknow

State/Province

Uttar Pradesh

ZIP/Postal Code

226014

Country

India

Facility Name

Novartis Investigative Site

City

Bangalore

ZIP/Postal Code

560 034

Country

India

Facility Name

Novartis Investigative Site

City

Hyderabad

ZIP/Postal Code

500 063

Country

India

Facility Name

Novartis Investigative Site

City

Hyderabad

ZIP/Postal Code

500044

Country

India

Facility Name

Novartis Investigative Site

City

Lucknow

ZIP/Postal Code

226003

Country

India

Facility Name

Novartis Investigative Site

City

Mumbai

ZIP/Postal Code

400 050

Country

India

Facility Name

Novartis Investigative Site

City

New Delhi

ZIP/Postal Code

110044

Country

India

Facility Name

Novartis Investigative Site

City

Noida

ZIP/Postal Code

201301

Country

India

Facility Name

Novartis Investigative Site

City

Co Dublin

Country

Ireland

Facility Name

Novartis Investigative Site

City

Dublin 7

Country

Ireland

Facility Name

Novartis Investigative Site

City

Dublin

ZIP/Postal Code

Country

Ireland

Facility Name

Novartis Investigative Site

City

Dublin

Country

Ireland

Facility Name

Novartis Investigative Site

City

Galway

Country

Ireland

Facility Name

Novartis Investigative Site

City

Montescano

State/Province

(pv)

ZIP/Postal Code

27040

Country

Italy

Facility Name

Novartis Investigative Site

City

Pavia

State/Province

(pv)

ZIP/Postal Code

27100

Country

Italy

Facility Name

Novartis Investigative Site

City

Ancona

State/Province

ZIP/Postal Code

60126

Country

Italy

Facility Name

Novartis Investigative Site

City

Arezzo

State/Province

ZIP/Postal Code

52100

Country

Italy

Facility Name

Novartis Investigative Site

City

Cortona

State/Province

ZIP/Postal Code

52044

Country

Italy

Facility Name

Novartis Investigative Site

City

Bergamo

State/Province

ZIP/Postal Code

24128

Country

Italy

Facility Name

Novartis Investigative Site

City

Bologna

State/Province

ZIP/Postal Code

40138

Country

Italy

Facility Name

Novartis Investigative Site

City

Brescia

State/Province

ZIP/Postal Code

25123

Country

Italy

Facility Name

Novartis Investigative Site

City

Lumezzane

State/Province

ZIP/Postal Code

25065

Country

Italy

Facility Name

Novartis Investigative Site

City

Chieti

State/Province

ZIP/Postal Code

66100

Country

Italy

Facility Name

Novartis Investigative Site

City

Cosenza

State/Province

ZIP/Postal Code

87100

Country

Italy

Facility Name

Novartis Investigative Site

City

Forlì

State/Province

ZIP/Postal Code

47100

Country

Italy

Facility Name

Novartis Investigative Site

City

Cona

State/Province

ZIP/Postal Code

44100

Country

Italy

Facility Name

Novartis Investigative Site

City

Foggia

State/Province

ZIP/Postal Code

71100

Country

Italy

Facility Name

Novartis Investigative Site

City

Firenze

State/Province

ZIP/Postal Code

50143

Country

Italy

Facility Name

Novartis Investigative Site

City

Pozzilli

State/Province

ZIP/Postal Code

86077

Country

Italy

Facility Name

Novartis Investigative Site

City

Casarano

State/Province

ZIP/Postal Code

73042

Country

Italy

Facility Name

Novartis Investigative Site

City

Cecina

State/Province

ZIP/Postal Code

57023

Country

Italy

Facility Name

Novartis Investigative Site

City

Castelnuovo di Garfagnana

State/Province

ZIP/Postal Code

55032

Country

Italy

Facility Name

Novartis Investigative Site

City

Milano

State/Province

ZIP/Postal Code

20132

Country

Italy

Facility Name

Novartis Investigative Site

City

Milano

State/Province

ZIP/Postal Code

20138

Country

Italy

Facility Name

Novartis Investigative Site

City

Passirana di Rho

State/Province

ZIP/Postal Code

20017

Country

Italy

Facility Name

Novartis Investigative Site

City

Pieve di Coriano

State/Province

Country

Italy

Facility Name

Novartis Investigative Site

City

Massa

State/Province

ZIP/Postal Code

54100

Country

Italy

Facility Name

Novartis Investigative Site

City

Palermo

State/Province

ZIP/Postal Code

90127

Country

Italy

Facility Name

Novartis Investigative Site

City

Perugia

State/Province

ZIP/Postal Code

06129

Country

Italy

Facility Name

Novartis Investigative Site

City

Parma

State/Province

ZIP/Postal Code

43100

Country

Italy

Facility Name

Novartis Investigative Site

City

Pavia

State/Province

ZIP/Postal Code

27100

Country

Italy

Facility Name

Novartis Investigative Site

City

Cotignola

State/Province

ZIP/Postal Code

48010

Country

Italy

Facility Name

Novartis Investigative Site

City

Roma

State/Province

ZIP/Postal Code

00169

Country

Italy

Facility Name

Novartis Investigative Site

City

Roma

State/Province

ZIP/Postal Code

00184

Country

Italy

Facility Name

Novartis Investigative Site

City

Roma

State/Province

ZIP/Postal Code

00189

Country

Italy

Facility Name

Novartis Investigative Site

City

Rimini

State/Province

ZIP/Postal Code

47900

Country

Italy

Facility Name

Novartis Investigative Site

City

Cava De' Tirreni

State/Province

ZIP/Postal Code

84013

Country

Italy

Facility Name

Novartis Investigative Site

City

Poggibonsi

State/Province

ZIP/Postal Code

53036

Country

Italy

Facility Name

Novartis Investigative Site

City

Sondalo

State/Province

ZIP/Postal Code

23035

Country

Italy

Facility Name

Novartis Investigative Site

City

Sarzana

State/Province

ZIP/Postal Code

19038

Country

Italy

Facility Name

Novartis Investigative Site

City

Sassari

State/Province

ZIP/Postal Code

07100

Country

Italy

Facility Name

Novartis Investigative Site

City

Orbassano

State/Province

ZIP/Postal Code

10043

Country

Italy

Facility Name

Novartis Investigative Site

City

Torino

State/Province

ZIP/Postal Code

10126

Country

Italy

Facility Name

Novartis Investigative Site

City

Terni

State/Province

ZIP/Postal Code

05100

Country

Italy

Facility Name

Novartis Investigative Site

City

Trieste

State/Province

ZIP/Postal Code

34142

Country

Italy

Facility Name

Novartis Investigative Site

City

Trieste

State/Province

ZIP/Postal Code

34149

Country

Italy

Facility Name

Novartis Investigative Site

City

Vittorio Veneto

State/Province

ZIP/Postal Code

31029

Country

Italy

Facility Name

Novartis Investigative Site

City

San Daniele Del Friuli

State/Province

ZIP/Postal Code

33038

Country

Italy

Facility Name

Novartis Investigative Site

City

Udine

State/Province

ZIP/Postal Code

33100

Country

Italy

Facility Name

Novartis Investigative Site

City

Tradate

State/Province

ZIP/Postal Code

21049

Country

Italy

Facility Name

Novartis Investigative Site

City

San Bonifacio

State/Province

ZIP/Postal Code

37047

Country

Italy

Facility Name

Novartis Investigative Site

City

Nagoya-city

State/Province

Aichi

ZIP/Postal Code

466-8560

Country

Japan

Facility Name

Novartis Investigative Site

City

Seto-city

State/Province

Aichi

ZIP/Postal Code

489-8642

Country

Japan

Facility Name

Novartis Investigative Site

City

Chiba-city

State/Province

Chiba

ZIP/Postal Code

260-8677

Country

Japan

Facility Name

Novartis Investigative Site

City

Inba-gun

State/Province

Chiba

ZIP/Postal Code

270-1694

Country

Japan

Facility Name

Novartis Investigative Site

City

Chikushino-city

State/Province

Fukuoka

ZIP/Postal Code

818-8502

Country

Japan

Facility Name

Novartis Investigative Site

City

Fukuoka-city

State/Province

Fukuoka

ZIP/Postal Code

814-0180

Country

Japan

Facility Name

Novartis Investigative Site

City

Iizuka-city

State/Province

Fukuoka

ZIP/Postal Code

820-8505

Country

Japan

Facility Name

Novartis Investigative Site

City

Kurume-city

State/Province

Fukuoka

ZIP/Postal Code

830-8577

Country

Japan

Facility Name

Novartis Investigative Site

City

Ogaki-city

State/Province

Gifu

ZIP/Postal Code

503-8502

Country

Japan

Facility Name

Novartis Investigative Site

City

Hiroshima-city

State/Province

Hiroshima

ZIP/Postal Code

734-8551

Country

Japan

Facility Name

Novartis Investigative Site

City

Kure

State/Province

Hiroshima

ZIP/Postal Code

737-0023

Country

Japan

Facility Name

Novartis Investigative Site

City

Sapporo-city

State/Province

Hokkaido

ZIP/Postal Code

060-8648

Country

Japan

Facility Name

Novartis Investigative Site

City

Sapporo-city

State/Province

Hokkaido

ZIP/Postal Code

063-0005

Country

Japan

Facility Name

Novartis Investigative Site

City

Amagasaki-city

State/Province

Hyogo

ZIP/Postal Code

660-8550

Country

Japan

Facility Name

Novartis Investigative Site

City

Higashiibaraki-gun

State/Province

Ibaraki

ZIP/Postal Code

311-3193

Country

Japan

Facility Name

Novartis Investigative Site

City

Hitachinaka

State/Province

Ibaraki

ZIP/Postal Code

312-0057

Country

Japan

Facility Name

Novartis Investigative Site

City

Tsukuba-city

State/Province

Ibaraki

ZIP/Postal Code

305-8576

Country

Japan

Facility Name

Novartis Investigative Site

City

Kanazawa

State/Province

Ishikawa

ZIP/Postal Code

920-8650

Country

Japan

Facility Name

Novartis Investigative Site

City

Kawasaki-city

State/Province

Kanagawa

ZIP/Postal Code

210-0852

Country

Japan

Facility Name

Novartis Investigative Site

City

Sagamihara-city

State/Province

Kanagawa

ZIP/Postal Code

252-0375

Country

Japan

Facility Name

Novartis Investigative Site

City

Yokohama-city

State/Province

Kanagawa

ZIP/Postal Code

232-0024

Country

Japan

Facility Name

Novartis Investigative Site

City

Yokosuka

State/Province

Kanagawa

ZIP/Postal Code

238-8567

Country

Japan

Facility Name

Novartis Investigative Site

City

Kumamoto City

State/Province

Kumamoto

ZIP/Postal Code

860-8556

Country

Japan

Facility Name

Novartis Investigative Site

City

Sendai-city

State/Province

Miyagi

ZIP/Postal Code

980-8574

Country

Japan

Facility Name

Novartis Investigative Site

City

Kashihara-city

State/Province

Nara

ZIP/Postal Code

634-8522

Country

Japan

Facility Name

Novartis Investigative Site

City

Okayama-city

State/Province

Okayama

ZIP/Postal Code

702-8055

Country

Japan

Facility Name

Novartis Investigative Site

City

Izumisano-city

State/Province

Osaka

ZIP/Postal Code

598-8577

Country

Japan

Facility Name

Novartis Investigative Site

City

Kita-ku

State/Province

Osaka

ZIP/Postal Code

530-0001

Country

Japan

Facility Name

Novartis Investigative Site

City

Osaka-city

State/Province

Osaka

ZIP/Postal Code

545-8586

Country

Japan

Facility Name

Novartis Investigative Site

City

Ureshino

State/Province

Saga

ZIP/Postal Code

843-0393

Country

Japan

Facility Name

Novartis Investigative Site

City

Hamada

State/Province

Shimane

ZIP/Postal Code

697-8511

Country

Japan

Facility Name

Novartis Investigative Site

City

Komatsushima-city

State/Province

Tokushima

ZIP/Postal Code

773-8502

Country

Japan

Facility Name

Novartis Investigative Site

City

Tokushima-city

State/Province

Tokushima

ZIP/Postal Code

770-8503

Country

Japan

Facility Name

Novartis Investigative Site

City

Adachi-ku

State/Province

Tokyo

ZIP/Postal Code

120-0006

Country

Japan

Facility Name

Novartis Investigative Site

City

Bunkyo-ku

State/Province

Tokyo

ZIP/Postal Code

113-8431

Country

Japan

Facility Name

Novartis Investigative Site

City

Bunkyo-ku

State/Province

Tokyo

ZIP/Postal Code

113-8519

Country

Japan

Facility Name

Novartis Investigative Site

City

Bunkyo-ku

State/Province

Tokyo

ZIP/Postal Code

113-8603

Country

Japan

Facility Name

Novartis Investigative Site

City

Bunkyo-ku

State/Province

Tokyo

ZIP/Postal Code

113-8655

Country

Japan

Facility Name

Novartis Investigative Site

City

Shinjuku-ku

State/Province

Tokyo

ZIP/Postal Code

162-8666

Country

Japan

Facility Name

Novartis Investigative Site

City

Hofu

State/Province

Yamaguchi

ZIP/Postal Code

747-8511

Country

Japan

Facility Name

Novartis Investigative Site

City

Shunan-city

State/Province

Yamaguchi

ZIP/Postal Code

745-8522

Country

Japan

Facility Name

Novartis Investigative Site

City

Ube

State/Province

Yamaguchi

ZIP/Postal Code

755-8505

Country

Japan

Facility Name

Novartis Investigative Site

City

Fukushima

ZIP/Postal Code

960-8251

Country

Japan

Facility Name

Novartis Investigative Site

City

Nagasaki

ZIP/Postal Code

850-8555

Country

Japan

Facility Name

Novartis Investigative Site

City

Saga

ZIP/Postal Code

849-8501

Country

Japan

Facility Name

Novartis Investigative Site

City

Toyama

ZIP/Postal Code

930-0194

Country

Japan

Facility Name

Novartis Investigative Site

City

Seongnam

State/Province

Gyeonggi

ZIP/Postal Code

13620

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Seoul

State/Province

Korea

ZIP/Postal Code

03080

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Seoul

State/Province

Korea

ZIP/Postal Code

03722

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Seoul

State/Province

Korea

ZIP/Postal Code

05505

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Seoul

State/Province

Korea

ZIP/Postal Code

06351

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Seoul

State/Province

Korea

ZIP/Postal Code

152-703

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Busan

ZIP/Postal Code

602-715

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Daejeon

ZIP/Postal Code

302-241

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Gwangju

ZIP/Postal Code

501-757

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Incheon

ZIP/Postal Code

405-760

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Seoul

ZIP/Postal Code

143-729

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Taegu

ZIP/Postal Code

700 - 721

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Daugavpils

ZIP/Postal Code

LV-5401

Country

Latvia

Facility Name

Novartis Investigative Site

City

Riga

ZIP/Postal Code

1012

Country

Latvia

Facility Name

Novartis Investigative Site

City

Riga

ZIP/Postal Code

LV-1012

Country

Latvia

Facility Name

Novartis Investigative Site

City

Riga

ZIP/Postal Code

LV-1038

Country

Latvia

Facility Name

Novartis Investigative Site

City

Kaunas

State/Province

LTU

ZIP/Postal Code

50009

Country

Lithuania

Facility Name

Novartis Investigative Site

City

Kaunas

ZIP/Postal Code

LT-47144

Country

Lithuania

Facility Name

Novartis Investigative Site

City

Klaipeda

ZIP/Postal Code

LT-92288

Country

Lithuania

Facility Name

Novartis Investigative Site

City

Vilnius

ZIP/Postal Code

08661

Country

Lithuania

Facility Name

Novartis Investigative Site

City

Guadalajara

State/Province

Jalisco

ZIP/Postal Code

44600

Country

Mexico

Facility Name

Novartis Investigative Site

City

Zapopan

State/Province

Jalisco

ZIP/Postal Code

45200

Country

Mexico

Facility Name

Novartis Investigative Site

City

Monterrey

State/Province

Nuevo León

ZIP/Postal Code

64060

Country

Mexico

Facility Name

Novartis Investigative Site

City

Monterrey

State/Province

Nuevo León

ZIP/Postal Code

64710

Country

Mexico

Facility Name

Novartis Investigative Site

City

Culiacan

State/Province

Sinaloa

ZIP/Postal Code

CP:83230

Country

Mexico

Facility Name

Novartis Investigative Site

City

Aguascalientes

ZIP/Postal Code

20230

Country

Mexico

Facility Name

Novartis Investigative Site

City

Querétaro

ZIP/Postal Code

76000

Country

Mexico

Facility Name

Novartis Investigative Site

City

San Luis Potosi

ZIP/Postal Code

78200

Country

Mexico

Facility Name

Novartis Investigative Site

City

Alkmaar

ZIP/Postal Code

1815 JD

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Amsterdam

ZIP/Postal Code

1023 NL

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Amsterdam

ZIP/Postal Code

1061 AE

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Amsterdam

ZIP/Postal Code

1091 HA

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Amsterdam

ZIP/Postal Code

1105 AZ

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Apeldoorn

ZIP/Postal Code

7334 DZ

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Deventer

ZIP/Postal Code

7416 SE

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Dirksland

ZIP/Postal Code

3247 BW

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Enschede

ZIP/Postal Code

7513 ER

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Groningen

ZIP/Postal Code

9713 GZ

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Haarlem

ZIP/Postal Code

2035 RC

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Heerlen

ZIP/Postal Code

6419 PC

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Leeuwarden

ZIP/Postal Code

8934 AD

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Leiderdorp

ZIP/Postal Code

NL-2353 GA

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Meppel

ZIP/Postal Code

7943 KA

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Rotterdam

ZIP/Postal Code

3045 PM

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Rotterdam

ZIP/Postal Code

3083 AN

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Venlo

ZIP/Postal Code

5912 BL

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Wildervank

ZIP/Postal Code

9648 BE

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Zutphen

ZIP/Postal Code

7207 AE

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Zwolle

ZIP/Postal Code

8011 JW

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Oslo

ZIP/Postal Code

0514

Country

Norway

Facility Name

Novartis Investigative Site

City

Trondheim

ZIP/Postal Code

7006

Country

Norway

Facility Name

Novartis Investigative Site

City

Tønsberg

ZIP/Postal Code

3116

Country

Norway

Facility Name

Novartis Investigative Site

City

Trujillo

State/Province

La Libertad

Country

Peru

Facility Name

Novartis Investigative Site

City

Chiclayo

State/Province

Lambayeque

Country

Peru

Facility Name

Novartis Investigative Site

City

Bellavista

State/Province

Lima

ZIP/Postal Code

Callao 02

Country

Peru

Facility Name

Novartis Investigative Site

City

Cercado de Lima

State/Province

Lima

ZIP/Postal Code

Country

Peru

Facility Name

Novartis Investigative Site

City

Jesus Maria

State/Province

Lima

ZIP/Postal Code

Country

Peru

Facility Name

Novartis Investigative Site

City

Miraflores

State/Province

Lima

ZIP/Postal Code

Country

Peru

Facility Name

Novartis Investigative Site

City

San Borja

State/Province

Lima

ZIP/Postal Code

Country

Peru

Facility Name

Novartis Investigative Site

City

San Isidro

State/Province

Lima

ZIP/Postal Code

Country

Peru

Facility Name

Novartis Investigative Site

City

San Juan de Miraflores

State/Province

Lima

ZIP/Postal Code

Country

Peru

Facility Name

Novartis Investigative Site

City

Lima

ZIP/Postal Code

Lima 39

Country

Peru

Facility Name

Novartis Investigative Site

City

Bytom

ZIP/Postal Code

41-902

Country

Poland

Facility Name

Novartis Investigative Site

City

Chorzow

ZIP/Postal Code

41-506

Country

Poland

Facility Name

Novartis Investigative Site

City

Gdansk

ZIP/Postal Code

80-180

Country

Poland

Facility Name

Novartis Investigative Site

City

Gdynia

ZIP/Postal Code

81-423

Country

Poland

Facility Name

Novartis Investigative Site

City

Gdynia

ZIP/Postal Code

81-519

Country

Poland

Facility Name

Novartis Investigative Site

City

Gliwice

ZIP/Postal Code

44-100

Country

Poland

Facility Name

Novartis Investigative Site

City

Grodzisk Mazowiecki

ZIP/Postal Code

05-825

Country

Poland

Facility Name

Novartis Investigative Site

City

Katowice

ZIP/Postal Code

40-040

Country

Poland

Facility Name

Novartis Investigative Site

City

Katowice

ZIP/Postal Code

40-084

Country

Poland

Facility Name

Novartis Investigative Site

City

Klodzko

ZIP/Postal Code

57-300

Country

Poland

Facility Name

Novartis Investigative Site

City

Krakow

ZIP/Postal Code

30-053

Country

Poland

Facility Name

Novartis Investigative Site

City

Kraków

ZIP/Postal Code

31-501

Country

Poland

Facility Name

Novartis Investigative Site

City

Lomza

ZIP/Postal Code

18-104

Country

Poland

Facility Name

Novartis Investigative Site

City

Olawa

ZIP/Postal Code

55-200

Country

Poland

Facility Name

Novartis Investigative Site

City

Opole

ZIP/Postal Code

45-706

Country

Poland

Facility Name

Novartis Investigative Site

City

Ostrow Wielkopolski

ZIP/Postal Code

63-400

Country

Poland

Facility Name

Novartis Investigative Site

City

Ostrowiec Swietokrzyski

ZIP/Postal Code

27-400

Country

Poland

Facility Name

Novartis Investigative Site

City

Piotrkow Trybunalski

ZIP/Postal Code

97-300

Country

Poland

Facility Name

Novartis Investigative Site

City

Plock

ZIP/Postal Code

09-402

Country

Poland

Facility Name

Novartis Investigative Site

City

Poznan

ZIP/Postal Code

61-485

Country

Poland

Facility Name

Novartis Investigative Site

City

Sandomierz

ZIP/Postal Code

27-600

Country

Poland

Facility Name

Novartis Investigative Site

City

Tarnow

ZIP/Postal Code

33-100

Country

Poland

Facility Name

Novartis Investigative Site

City

Torun

ZIP/Postal Code

87-100

Country

Poland

Facility Name

Novartis Investigative Site

City

Warszawa

ZIP/Postal Code

03-242

Country

Poland

Facility Name

Novartis Investigative Site

City

Warszawa

ZIP/Postal Code

04-628

Country

Poland

Facility Name

Novartis Investigative Site

City

Wroclaw

ZIP/Postal Code

50-349

Country

Poland

Facility Name

Novartis Investigative Site

City

Wroclaw

ZIP/Postal Code

50-420

Country

Poland

Facility Name

Novartis Investigative Site

City

Wroclaw

ZIP/Postal Code

50-981

Country

Poland

Facility Name

Novartis Investigative Site

City

Wroclaw

ZIP/Postal Code

52-612

Country

Poland

Facility Name

Novartis Investigative Site

City

Zabrze

ZIP/Postal Code

41-800

Country

Poland

Facility Name

Novartis Investigative Site

City

Amadora

ZIP/Postal Code

2720-276

Country

Portugal

Facility Name

Novartis Investigative Site

City

Aveiro

ZIP/Postal Code

3814-501

Country

Portugal

Facility Name

Novartis Investigative Site

City

Carnaxide

ZIP/Postal Code

2799-523

Country

Portugal

Facility Name

Novartis Investigative Site

City

Coimbra

ZIP/Postal Code

3000-075

Country

Portugal

Facility Name

Novartis Investigative Site

City

Faro

ZIP/Postal Code

8000-386

Country

Portugal

Facility Name

Novartis Investigative Site

City

Lisboa

ZIP/Postal Code

1495-005

Country

Portugal

Facility Name

Novartis Investigative Site

City

Lisboa

ZIP/Postal Code

1600-190

Country

Portugal

Facility Name

Novartis Investigative Site

City

Lisboa

ZIP/Postal Code

1769-001

Country

Portugal

Facility Name

Novartis Investigative Site

City

Penafiel

ZIP/Postal Code

4564-007

Country

Portugal

Facility Name

Novartis Investigative Site

City

Porto

ZIP/Postal Code

4200-319

Country

Portugal

Facility Name

Novartis Investigative Site

City

Humacao

ZIP/Postal Code

00791

Country

Puerto Rico

Facility Name

Novartis Investigative Site

City

Ponce

ZIP/Postal Code

00717

Country

Puerto Rico

Facility Name

Novartis Investigative Site

City

San Juan

ZIP/Postal Code

00936-6528

Country

Puerto Rico

Facility Name

Novartis Investigative Site

City

Bucharest

State/Province

District 1

ZIP/Postal Code

012051

Country

Romania

Facility Name

Novartis Investigative Site

City

Bucharest

State/Province

District 1

ZIP/Postal Code

012064

Country

Romania

Facility Name

Novartis Investigative Site

City

Bucharest

State/Province

District 2

ZIP/Postal Code

021705

Country

Romania

Facility Name

Novartis Investigative Site

City

Iasi

State/Province

Jud Iasi

ZIP/Postal Code

700005

Country

Romania

Facility Name

Novartis Investigative Site

City

Targu Mures

State/Province

jud Mures

ZIP/Postal Code

540043

Country

Romania

Facility Name

Novartis Investigative Site

City

Iasi

State/Province

Jud. Iasi

ZIP/Postal Code

700506

Country

Romania

Facility Name

Novartis Investigative Site

City

Targu Mures

State/Province

Mures

ZIP/Postal Code

540136

Country

Romania

Facility Name

Novartis Investigative Site

City

Baia Mare

ZIP/Postal Code

430123

Country

Romania

Facility Name

Novartis Investigative Site

City

Brasov

ZIP/Postal Code

500281

Country

Romania

Facility Name

Novartis Investigative Site

City

Brasov

ZIP/Postal Code

500427

Country

Romania

Facility Name

Novartis Investigative Site

City

Cluj Napoca

ZIP/Postal Code

400006

Country

Romania

Facility Name

Novartis Investigative Site

City

Cluj-Napoca

ZIP/Postal Code

400347

Country

Romania

Facility Name

Novartis Investigative Site

City

Iasi

ZIP/Postal Code

700547

Country

Romania

Facility Name

Novartis Investigative Site

City

Oradea

ZIP/Postal Code

410169

Country

Romania

Facility Name

Novartis Investigative Site

City

Pitesti

ZIP/Postal Code

110114

Country

Romania

Facility Name

Novartis Investigative Site

City

Targu Mures

ZIP/Postal Code

540096

Country

Romania

Facility Name

Novartis Investigative Site

City

Timisoara

ZIP/Postal Code

300310

Country

Romania

Facility Name

Novartis Investigative Site

City

Timisoara

ZIP/Postal Code

300736

Country

Romania

Facility Name

Novartis Investigative Site

City

Barnaul

ZIP/Postal Code

656055

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Chelyabinsk

ZIP/Postal Code

454000

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Chelyabinsk

ZIP/Postal Code

454021

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Chelyabinsk

ZIP/Postal Code

454047

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Chelyabinsk

ZIP/Postal Code

454048

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Ekaterinburg

ZIP/Postal Code

620028

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Ekaterinburg

ZIP/Postal Code

620137

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Izhevsk

ZIP/Postal Code

426009

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Kirov

ZIP/Postal Code

610014

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Krasnodar

ZIP/Postal Code

350063

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Kursk

ZIP/Postal Code

305035

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Lubertsi

ZIP/Postal Code

140006

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Moscow

ZIP/Postal Code

105229

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Moscow

ZIP/Postal Code

111020

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Moscow

ZIP/Postal Code

111539

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Moscow

ZIP/Postal Code

115432

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Moscow

ZIP/Postal Code

117292

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Moscow

ZIP/Postal Code

119992

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Moscow

ZIP/Postal Code

121359

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Moscow

ZIP/Postal Code

127473

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Moscow

ZIP/Postal Code

129301

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Moscow

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Nizhny Novgorod

ZIP/Postal Code

603018

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Novosibirsk

ZIP/Postal Code

630047

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Novosibirsk

ZIP/Postal Code

630075

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Novosibirsk

ZIP/Postal Code

630089

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Omsk

ZIP/Postal Code

644018

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Perm

ZIP/Postal Code

614097

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Pushkin,St-Petersburg

ZIP/Postal Code

196601

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Ryazan

ZIP/Postal Code

390026

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

S.-Petersburg

ZIP/Postal Code

196247

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Saint Petersburg

ZIP/Postal Code

197022

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Saint-Petersburg

ZIP/Postal Code

194044

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Saint-Petersburg

ZIP/Postal Code

197341

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Saratov

ZIP/Postal Code

410012

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Saratov

ZIP/Postal Code

410028

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

St-Petersburg

ZIP/Postal Code

191119

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

St. Petersburg

ZIP/Postal Code

198013

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Tyumen

ZIP/Postal Code

625026

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Volgograd

ZIP/Postal Code

400001

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Volgograd

ZIP/Postal Code

400008

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Voronezh

ZIP/Postal Code

394065

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Yaroslavl

ZIP/Postal Code

150000

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Yaroslavl

ZIP/Postal Code

150030

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Yaroslavl

ZIP/Postal Code

150062

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Bratislava

State/Province

Slovak Republic

ZIP/Postal Code

812 72

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Bratislava

State/Province

Slovak Republic

ZIP/Postal Code

826 06

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Komarno

State/Province

Slovak Republic

ZIP/Postal Code

94575

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Kosice

State/Province

Slovak Republic

ZIP/Postal Code

040 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Kosice

State/Province

Slovak republic

ZIP/Postal Code

04166

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Levice

State/Province

Slovak Republic

ZIP/Postal Code

93401

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Nitra

State/Province

Slovak Republic

ZIP/Postal Code

949 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Povazska Bystrica

State/Province

Slovak republic

ZIP/Postal Code

01701

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Presov

State/Province

Slovak republic

ZIP/Postal Code

08101

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Stropkov

State/Province

Slovak republic

ZIP/Postal Code

09101

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Zilina

State/Province

Slovak Republic

ZIP/Postal Code

010 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Zilina

State/Province

Slovak Republic

ZIP/Postal Code

08001

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Bardejov

ZIP/Postal Code

085 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Bratislava

ZIP/Postal Code

81369

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Kosice

ZIP/Postal Code

040 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Kosice

ZIP/Postal Code

04001

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Lucenec

ZIP/Postal Code

98439

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Piestany

ZIP/Postal Code

921 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Presov

ZIP/Postal Code

080 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Trebisov

ZIP/Postal Code

075 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Trencin

ZIP/Postal Code

911 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Zilina

ZIP/Postal Code

012 07

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Soweto

State/Province

Gauteng

ZIP/Postal Code

2013

Country

South Africa

Facility Name

Novartis Investigative Site

City

Benoni

Country

South Africa

Facility Name

Novartis Investigative Site

City

Boksburg

Country

South Africa

Facility Name

Novartis Investigative Site

City

Centurion

ZIP/Postal Code

4001

Country

South Africa

Facility Name

Novartis Investigative Site

City

Johannesburg

ZIP/Postal Code

2157

Country

South Africa

Facility Name

Novartis Investigative Site

City

Western Cape

ZIP/Postal Code

7130

Country

South Africa

Facility Name

Novartis Investigative Site

City

Worcester

ZIP/Postal Code

6850

Country

South Africa

Facility Name

Novartis Investigative Site

City

Sanlucar de Barrameda

State/Province

Andalucia

ZIP/Postal Code

11540

Country

Spain

Facility Name

Novartis Investigative Site

City

Sevilla

State/Province

Andalucia

ZIP/Postal Code

41009

Country

Spain

Facility Name

Novartis Investigative Site

City

Utrera

State/Province

Andalucia

ZIP/Postal Code

41710

Country

Spain

Facility Name

Novartis Investigative Site

City

Oviedo

State/Province

Asturias

ZIP/Postal Code

33011

Country

Spain

Facility Name

Novartis Investigative Site

City

Hospitalet de Llobregat

State/Province

Barcelona

ZIP/Postal Code

08907

Country

Spain

Facility Name

Novartis Investigative Site

City

Villamartin

State/Province

Cadiz

ZIP/Postal Code

11650

Country

Spain

Facility Name

Novartis Investigative Site

City

Badalona

State/Province

Catalunya

ZIP/Postal Code

08916

Country

Spain

Facility Name

Novartis Investigative Site

City

Barcelona

State/Province

Catalunya

ZIP/Postal Code

08035

Country

Spain

Facility Name

Novartis Investigative Site

City

Barcelona

State/Province

Catalunya

ZIP/Postal Code

08036

Country

Spain

Facility Name

Novartis Investigative Site

City

Tarragona

State/Province

Catalunya

ZIP/Postal Code

43005

Country

Spain

Facility Name

Novartis Investigative Site

City

Tortosa

State/Province

Cataluña

ZIP/Postal Code

43500

Country

Spain

Facility Name

Novartis Investigative Site

City

Alicante

State/Province

Comunidad Valenciana

ZIP/Postal Code

03004

Country

Spain

Facility Name

Novartis Investigative Site

City

Valencia

State/Province

Comunidad Valenciana

ZIP/Postal Code

46014

Country

Spain

Facility Name

Novartis Investigative Site

City

Santiago de Compostela

State/Province

Galicia

ZIP/Postal Code

15706

Country

Spain

Facility Name

Novartis Investigative Site

City

Majadahonda

State/Province

Madrid

ZIP/Postal Code

28222

Country

Spain

Facility Name

Novartis Investigative Site

City

Valdemoro

State/Province

Madrid

ZIP/Postal Code

28342

Country

Spain

Facility Name

Novartis Investigative Site

City

Barcelona

ZIP/Postal Code

08041

Country

Spain

Facility Name

Novartis Investigative Site

City

Madrid

ZIP/Postal Code

28007

Country

Spain

Facility Name

Novartis Investigative Site

City

Madrid

ZIP/Postal Code

28040

Country

Spain

Facility Name

Novartis Investigative Site

City

Madrid

ZIP/Postal Code

28041

Country

Spain

Facility Name

Novartis Investigative Site

City

Madrid

ZIP/Postal Code

28046

Country

Spain

Facility Name

Novartis Investigative Site

City

Madrid

ZIP/Postal Code

28049

Country

Spain

Facility Name

Novartis Investigative Site

City

Falun

ZIP/Postal Code

791 82

Country

Sweden

Facility Name

Novartis Investigative Site

City

Göteborg

ZIP/Postal Code

416 85

Country

Sweden

Facility Name

Novartis Investigative Site

City

Karlstad

ZIP/Postal Code

681 85

Country

Sweden

Facility Name

Novartis Investigative Site

City

Linkoping

ZIP/Postal Code

581 85

Country

Sweden

Facility Name

Novartis Investigative Site

City

Lund

ZIP/Postal Code

SE-222 21

Country

Sweden

Facility Name

Novartis Investigative Site

City

Malmo

ZIP/Postal Code

SE 211 36

Country

Sweden

Facility Name

Novartis Investigative Site

City

Malmö

ZIP/Postal Code

205 02

Country

Sweden

Facility Name

Novartis Investigative Site

City

Malmö

ZIP/Postal Code

214 22

Country

Sweden

Facility Name

Novartis Investigative Site

City

Mölndal

ZIP/Postal Code

431 80

Country

Sweden

Facility Name

Novartis Investigative Site

City

Nässjö

ZIP/Postal Code

SE 571 31

Country

Sweden

Facility Name

Novartis Investigative Site

City

Skelleftea

ZIP/Postal Code

931 86

Country

Sweden

Facility Name

Novartis Investigative Site

City

Stockholm

ZIP/Postal Code

111 57

Country

Sweden

Facility Name

Novartis Investigative Site

City

Stockholm

ZIP/Postal Code

112 81

Country

Sweden

Facility Name

Novartis Investigative Site

City

Stockholm

ZIP/Postal Code

17176

Country

Sweden

Facility Name

Novartis Investigative Site

City

Stockholm

ZIP/Postal Code

SE-111 35

Country

Sweden

Facility Name

Novartis Investigative Site

City

Sundsvall

ZIP/Postal Code

851 86

Country

Sweden

Facility Name

Novartis Investigative Site

City

Sundsvall

ZIP/Postal Code

852 31

Country

Sweden

Facility Name

Novartis Investigative Site

City

Umeå

ZIP/Postal Code

901 85

Country

Sweden

Facility Name

Novartis Investigative Site

City

Uppsala

ZIP/Postal Code

SE-751 85

Country

Sweden

Facility Name

Novartis Investigative Site

City

Västerås

ZIP/Postal Code

s-721 89

Country

Sweden

Facility Name

Novartis Investigative Site

City

Örebro

ZIP/Postal Code

701 85

Country

Sweden

Facility Name

Novartis Investigative Site

City

Basel

ZIP/Postal Code

4031

Country

Switzerland

Facility Name

Novartis Investigative Site

City

Bellinzona

ZIP/Postal Code

6500

Country

Switzerland

Facility Name

Novartis Investigative Site

City

Bern

ZIP/Postal Code

3010

Country

Switzerland

Facility Name

Novartis Investigative Site

City

Biel

ZIP/Postal Code

2500

Country

Switzerland

Facility Name

Novartis Investigative Site

City

Bruderholz

ZIP/Postal Code

4101

Country

Switzerland

Facility Name

Novartis Investigative Site

City

Lugano

ZIP/Postal Code

6903

Country

Switzerland

Facility Name

Novartis Investigative Site

City

Olten

ZIP/Postal Code

4600

Country

Switzerland

Facility Name

Novartis Investigative Site

City

Winterthur

ZIP/Postal Code

8401

Country

Switzerland

Facility Name

Novartis Investigative Site

City

Zuerich

ZIP/Postal Code

8091

Country

Switzerland

Facility Name

Novartis Investigative Site

City

Yongkang

State/Province

Tainan

ZIP/Postal Code

71004

Country

Taiwan

Facility Name

Novartis Investigative Site

City

Tainan 704

State/Province

Taiwan ROC

ZIP/Postal Code

70403

Country

Taiwan

Facility Name

Novartis Investigative Site

City

Kaohsiung

ZIP/Postal Code

807

Country

Taiwan

Facility Name

Novartis Investigative Site

City

Lin-Kou

ZIP/Postal Code

33305

Country

Taiwan

Facility Name

Novartis Investigative Site

City

Niaosong Township

ZIP/Postal Code

83301

Country

Taiwan

Facility Name

Novartis Investigative Site

City

Taichung

ZIP/Postal Code

40447

Country

Taiwan

Facility Name

Novartis Investigative Site

City

Taipei

ZIP/Postal Code

10002

Country

Taiwan

Facility Name

Novartis Investigative Site

City

Taipei

ZIP/Postal Code

104

Country

Taiwan

Facility Name

Novartis Investigative Site

City

Bangkok

ZIP/Postal Code

10330

Country

Thailand

Facility Name

Novartis Investigative Site

City

Bangkok

ZIP/Postal Code

10400

Country

Thailand

Facility Name

Novartis Investigative Site

City

Bangkok

ZIP/Postal Code

10700

Country

Thailand

Facility Name

Novartis Investigative Site

City

Chiang Mai

ZIP/Postal Code

50200

Country

Thailand

Facility Name

Novartis Investigative Site

City

Ankara

ZIP/Postal Code

06100

Country

Turkey

Facility Name

Novartis Investigative Site

City

Aydin

ZIP/Postal Code

09100

Country

Turkey

Facility Name

Novartis Investigative Site

City

Balcova / Izmir

ZIP/Postal Code

35340

Country

Turkey

Facility Name

Novartis Investigative Site

City

Etlik / Ankara

ZIP/Postal Code

06018

Country

Turkey

Facility Name

Novartis Investigative Site

City

Fatih / Istanbul

ZIP/Postal Code

34098

Country

Turkey

Facility Name

Novartis Investigative Site

City

Istanbul

ZIP/Postal Code

34304

Country

Turkey

Facility Name

Novartis Investigative Site

City

Izmir

ZIP/Postal Code

35040

Country

Turkey

Facility Name

Novartis Investigative Site

City

Kinikli / Denizli

ZIP/Postal Code

20070

Country

Turkey

Facility Name

Novartis Investigative Site

City

Kocaeli

ZIP/Postal Code

41380

Country

Turkey

Facility Name

Novartis Investigative Site

City

Sivas

ZIP/Postal Code

58140

Country

Turkey

Facility Name

Novartis Investigative Site

City

Leicester

State/Province

Leicestershire

ZIP/Postal Code

LE3 9QP

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Dafen

State/Province

Llanelli

ZIP/Postal Code

SA14 8QF

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Addlestone

State/Province

Surrey

ZIP/Postal Code

KT15 2BH

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Chichester

State/Province

West Sussex

ZIP/Postal Code

PO19 6SE

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Worthing

State/Province

West Sussex

ZIP/Postal Code

BN11 2DH

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Cardiff

ZIP/Postal Code

CF5 4AD

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Chesterfield

ZIP/Postal Code

S44 5BL

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Colchester

ZIP/Postal Code

CO4 5JL

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

East Yorkshire

ZIP/Postal Code

HU16 5JQ

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Glasgow

ZIP/Postal Code

G51 4TF

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Liverpool

ZIP/Postal Code

L14 3PE

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

London

ZIP/Postal Code

SE1 7EH

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

London

ZIP/Postal Code

SW17 0RE

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Manchester

ZIP/Postal Code

M23 9LT

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Southampton

ZIP/Postal Code

SO16 6YD

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Swindon

ZIP/Postal Code

SN3 6BB

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Caracas

State/Province

Distrito Capital

ZIP/Postal Code

1010

Country

Venezuela

Facility Name

Novartis Investigative Site

City

Caracas

State/Province

Distrito Capital

ZIP/Postal Code

1040

Country

Venezuela

Facility Name

Novartis Investigative Site

City

Caracas

State/Province

Distrito Capital

ZIP/Postal Code

1060

Country

Venezuela

Facility Name

Novartis Investigative Site

City

Valencia

State/Province

Edo. Carabobo

ZIP/Postal Code

2001

Country

Venezuela

Facility Name

Novartis Investigative Site

City

Barcelona

State/Province

Estado Anzoátegui

ZIP/Postal Code

6001

Country

Venezuela

Facility Name

Novartis Investigative Site

City

Puerto Ordaz

State/Province

Estado Bolívar

ZIP/Postal Code

8050

Country

Venezuela

Facility Name

Novartis Investigative Site

City

Caracas

State/Province

Estado Miranda

ZIP/Postal Code

1061

Country

Venezuela

Facility Name

Novartis Investigative Site

City

Cumana

State/Province

Estado Sucre

ZIP/Postal Code

6101

Country

Venezuela

Facility Name

Novartis Investigative Site

City

Maracaibo

State/Province

Estado Zulia

ZIP/Postal Code

4011

Country

Venezuela

12. IPD Sharing Statement

Citations:

PubMed Identifier

34101002

Citation

Shen L, Claggett BL, Jhund PS, Abraham WT, Desai AS, Dickstein K, Gong J, Kober LV, Lefkowitz MP, Rouleau JL, Shi VC, Swedberg K, Zile MR, Solomon SD, McMurray JJV. Development and external validation of prognostic models to predict sudden and pump-failure death in patients with HFrEF from PARADIGM-HF and ATMOSPHERE. Clin Res Cardiol. 2021 Aug;110(8):1334-1349. doi: 10.1007/s00392-021-01888-x. Epub 2021 Jun 8.

Results Reference

derived

PubMed Identifier

33089502

Citation

Wang GM, Li LJ, Tang WL, Wright JM. Renin inhibitors versus angiotensin converting enzyme (ACE) inhibitors for primary hypertension. Cochrane Database Syst Rev. 2020 Oct 22;10(10):CD012569. doi: 10.1002/14651858.CD012569.pub2.

Results Reference

derived

PubMed Identifier

32720404

Citation

Kristensen SL, Castagno D, Shen L, Jhund PS, Docherty KF, Rorth R, Abraham WT, Desai AS, Dickstein K, Rouleau JL, Zile MR, Swedberg K, Packer M, Solomon SD, Kober L, McMurray JJV; PARADIGM-HF and ATMOSPHERE Committees and Investigators.. Prevalence and incidence of intra-ventricular conduction delays and outcomes in patients with heart failure and reduced ejection fraction: insights from PARADIGM-HF and ATMOSPHERE. Eur J Heart Fail. 2020 Dec;22(12):2370-2379. doi: 10.1002/ejhf.1972. Epub 2020 Sep 14.

Results Reference

derived

PubMed Identifier

31849164

Citation

Docherty KF, Shen L, Castagno D, Petrie MC, Abraham WT, Bohm M, Desai AS, Dickstein K, Kober LV, Packer M, Rouleau JL, Solomon SD, Swedberg K, Vazir A, Zile MR, Jhund PS, McMurray JJV. Relationship between heart rate and outcomes in patients in sinus rhythm or atrial fibrillation with heart failure and reduced ejection fraction. Eur J Heart Fail. 2020 Mar;22(3):528-538. doi: 10.1002/ejhf.1682. Epub 2019 Dec 17.

Results Reference

derived

PubMed Identifier

31813280

Citation

Dewan P, Rorth R, Raparelli V, Campbell RT, Shen L, Jhund PS, Petrie MC, Anand IS, Carson PE, Desai AS, Granger CB, Kober L, Komajda M, McKelvie RS, O'Meara E, Pfeffer MA, Pitt B, Solomon SD, Swedberg K, Zile MR, McMurray JJV. Sex-Related Differences in Heart Failure With Preserved Ejection Fraction. Circ Heart Fail. 2019 Dec;12(12):e006539. doi: 10.1161/CIRCHEARTFAILURE.119.006539. Epub 2019 Dec 9. Erratum In: Circ Heart Fail. 2020 Jan;13(1):e000036.

Results Reference

derived

PubMed Identifier

29141857

Citation

Shen L, Ramires F, Martinez F, Bodanese LC, Echeverria LE, Gomez EA, Abraham WT, Dickstein K, Kober L, Packer M, Rouleau JL, Solomon SD, Swedberg K, Zile MR, Jhund PS, Gimpelewicz CR, McMurray JJV; PARADIGM-HF and ATMOSPHERE Investigators and Committees. Contemporary Characteristics and Outcomes in Chagasic Heart Failure Compared With Other Nonischemic and Ischemic Cardiomyopathy. Circ Heart Fail. 2017 Nov;10(11):e004361. doi: 10.1161/CIRCHEARTFAILURE.117.004361.

Results Reference

derived

PubMed Identifier

29018174

Citation

Kristensen SL, Jhund PS, Mogensen UM, Rorth R, Abraham WT, Desai A, Dickstein K, Rouleau JL, Zile MR, Swedberg K, Packer M, Solomon SD, Kober L, McMurray JJV; PARADIGM-HF and ATMOSPHERE Committees and Investigators. Prognostic Value of N-Terminal Pro-B-Type Natriuretic Peptide Levels in Heart Failure Patients With and Without Atrial Fibrillation. Circ Heart Fail. 2017 Oct;10(10):e004409. doi: 10.1161/CIRCHEARTFAILURE.117.004409.

Results Reference

derived

PubMed Identifier

28948656

Citation

Kristensen SL, Mogensen UM, Tarnesby G, Gimpelewicz CR, Ali MA, Shao Q, Chiang Y, Jhund PS, Abraham WT, Dickstein K, McMurray JJV, Kober L. Aliskiren alone or in combination with enalapril vs. enalapril among patients with chronic heart failure with and without diabetes: a subgroup analysis from the ATMOSPHERE trial. Eur J Heart Fail. 2018 Jan;20(1):136-147. doi: 10.1002/ejhf.896. Epub 2017 Sep 25.

Results Reference

derived

PubMed Identifier

27043774

Citation

McMurray JJ, Krum H, Abraham WT, Dickstein K, Kober LV, Desai AS, Solomon SD, Greenlaw N, Ali MA, Chiang Y, Shao Q, Tarnesby G, Massie BM; ATMOSPHERE Committees Investigators. Aliskiren, Enalapril, or Aliskiren and Enalapril in Heart Failure. N Engl J Med. 2016 Apr 21;374(16):1521-32. doi: 10.1056/NEJMoa1514859. Epub 2016 Apr 4.

Results Reference

derived

Learn more about this trial

Efficacy and Safety of Aliskiren and Aliskiren/Enalapril Combination on Morbidity-mortality in Patients With Chronic Heart Failure

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Efficacy and Safety of Aliskiren and Aliskiren/Enalapril Combination on Morbidity-mortality in Patients With Chronic Heart Failure (ATMOSPHERE)

Chronic Heart Failure

About this trial

Eligibility Criteria

Sites / Locations

Arms of the Study

Arm 1

Arm 2

Arm 3

Outcomes

Primary Outcome Measures

Secondary Outcome Measures

Full Information

1. Study Identification

2. Study Status

3. Sponsor/Collaborators

4. Oversight

5. Study Description

6. Conditions and Keywords

7. Study Design

8. Arms, Groups, and Interventions

10. Eligibility

12. IPD Sharing Statement

Learn more about this trial