Electrical Stimulation for Recovery of Hand Function in Chronic Stroke Survivors
Stroke, Hemiparesis, Hemiplegia
About this trial
This is an interventional treatment trial for Stroke focused on measuring hand, stroke, hemiplegia, electrical stimulation, recovery
Eligibility Criteria
Inclusion Criteria:
- Age 18-80
- > 6 months of first hemorrhagic or nonhemorrhagic stroke
- Able to recall 2 of 3 items after 30 minutes
- MRC ≤ 4 for finger extensors on paretic side
- Able to follow 3-stage commands
- Functional movement of shoulder and elbow (e.g., can reach ¾ hand-to- mouth movement) of paretic side
- Caregiver available to assist with device and compliance if needed
- Skin intact on hemiparetic arm
- Medically stable
- Surface NMES trial opens hand without pain
- Full volitional hand opening/closing of contralateral hand
- Upper extremity hand section of FMA < 11/14
- Able to hear and respond to stimulator/cue box auditory cues
- Completed occupational therapy (no concomitant OT)
Exclusion Criteria:
- Lack of functional PROM of the wrist or fingers of affected side
- Severe shoulder or hand pain (unable to position hand in the workspace without pain)
- Uncontrolled seizure disorder
- Insensate forearm and/or hand
- Uncompensated hemi-neglect (extinguishing to double simultaneous stimulation)
- Edema of the affected forearm and/or hand
- History of cardiac arrhythmias with hemodynamic instability
- Cardiac pacemaker or other implanted electronic system
- Pregnant
- IM Botox injections in any UE muscle in the last 3 months
- Parkinson's disease, SCI, TBI, or MS
- Ipsilateral motor neuron lesion
Sites / Locations
- MetroHealth Medical Center
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
CCFES
cNMES
CCFES - Contralaterally Controlled Functional Electrical Stimulation Electrical stimulator Stimulation to finger and thumb extensors only in response to, and with an intensity proportional to, opening of the contralateral unimpaired hand. A glove instrumented with sensors and worn on the unimpaired hand detects the degree of hand opening and determines stimulation intensity. Therapy sessions are done with the subject being assisted by the CCFES system.
cNMES - Cyclic NeuroMuscular Electrical Stimulation Electrical stimulator Preprogrammed cycles of finger and thumb extensor stimulation repeatedly and automatically open the hand. Subject instructed to not move the contralateral arm/hand during stimulation. Therapy sessions are done without the stimulation system.