Influence of Fibrin Glue on Seroma Formation After Modified Radical Mastectomy (MRM)
Breast Cancer
About this trial
This is an interventional prevention trial for Breast Cancer focused on measuring fibrin glue, seroma, mastectomy
Eligibility Criteria
Inclusion Criteria:
- Patients with operable breast cancer
Exclusion Criteria:
- Patients who received preoperative chemotherapy and radiotherapy were exclude
- Patients with previous axillary surgery
- Patients who underwent simultaneous reconstructive surgery and breast conservative surgery
- Locally advanced breast cancer
Sites / Locations
- Ayman Elnakeeb
- Ayman Elnakeeb
Arms of the Study
Arm 1
Arm 2
Active Comparator
No Intervention
1 fibrin glue
2 non fibrin glue
8 ml of fibrin glue was sprayed on the surgical area with Y canula ( doubleject application system).One milliliter of fibrin glue contains 70-100 mg. fibrinogen, 10-50 u factor 8 aprotinin 3000k iu/ml, 2-9 mg fibronectin,40-120 ug plasminogen ,4 Iu/ml thrombin, 40 mmol cocl2/L (immuno AG/austrial)
after good haemostasis the same sized drain was applied in axillary and breast area and incision was closed. Followed by external compression for 10 minutes in both groups. Drains were left in places until the drainage for the preceding 24 h was less than 20 ml.