Back to resultsEffect of Turmeric on Pruritus in Hemodialysis Patients
Primary Purpose
End Stage Renal Failure
Status
Completed
Phase
Early Phase 1
Locations
Iran, Islamic Republic of
Study Type
Interventional
Intervention
turmeric
placebo
turmeric
Sponsored by
About this trial
This is an interventional treatment trial for End Stage Renal Failure focused on measuring hemodialysis, turmeric, pruritus
Eligibility Criteria
Inclusion Criteria:
- Hemodialysis for more than 3 months
- More than 18 years old
- Pruritus
Exclusion Criteria:
- Use other treatment for pruritus
Sites / Locations
- Shiraz University Hemodialysis Center
Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
Placebo Comparator
Arm Label
turmeric
plasebo
Arm Description
turmeric 500 mg tid orally for 8 weeks
placebo tid orally for 8 weeks
Outcomes
Primary Outcome Measures
improvement in pruritus
Secondary Outcome Measures
Full Information
NCT ID
NCT01037595
First Posted
December 22, 2009
Last Updated
May 12, 2013
Sponsor
Shiraz University of Medical Sciences
1. Study Identification
Unique Protocol Identification Number
NCT01037595
Brief Title
Effect of Turmeric on Pruritus in Hemodialysis Patients
Study Type
Interventional
2. Study Status
Record Verification Date
May 2013
Overall Recruitment Status
Completed
Study Start Date
September 2010 (undefined)
Primary Completion Date
October 2010 (Actual)
Study Completion Date
December 2010 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Shiraz University of Medical Sciences
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
The purpose of this study is to see whether turmeric can be effective in treatment of pruritus in hemodialysis patients.
Detailed Description
pruritus is a common in hemodialysis patients and many treatment recommended for it . as turmeric has anti-inflammatory , anti-cytokine and anti-oxidant effect it may effective in treatment of uremic pruritus. thus we compared turmeric with placebo in this study
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
End Stage Renal Failure
Keywords
hemodialysis, turmeric, pruritus
7. Study Design
Primary Purpose
Treatment
Study Phase
Early Phase 1
Interventional Study Model
Parallel Assignment
Masking
ParticipantInvestigator
Allocation
Randomized
Enrollment
60 (Actual)
8. Arms, Groups, and Interventions
Arm Title
turmeric
Arm Type
Experimental
Arm Description
turmeric 500 mg tid orally for 8 weeks
Arm Title
plasebo
Arm Type
Placebo Comparator
Arm Description
placebo tid orally for 8 weeks
Intervention Type
Drug
Intervention Name(s)
turmeric
Intervention Description
turmeric 500 md tid orally for 8 weeks
Intervention Type
Drug
Intervention Name(s)
placebo
Intervention Description
placebo 3 time orally for 8 weeks
Intervention Type
Drug
Intervention Name(s)
turmeric
Intervention Description
500 mg tid orally for 8 weeks
Primary Outcome Measure Information:
Title
improvement in pruritus
Time Frame
6 mo
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
70 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
Hemodialysis for more than 3 months
More than 18 years old
Pruritus
Exclusion Criteria:
Use other treatment for pruritus
Facility Information:
Facility Name
Shiraz University Hemodialysis Center
City
Shiraz
State/Province
Fars
ZIP/Postal Code
098
Country
Iran, Islamic Republic of
12. IPD Sharing Statement
Citations:
PubMed Identifier
33283264
Citation
Hercz D, Jiang SH, Webster AC. Interventions for itch in people with advanced chronic kidney disease. Cochrane Database Syst Rev. 2020 Dec 7;12(12):CD011393. doi: 10.1002/14651858.CD011393.pub2.
Results Reference
derived
Learn more about this trial
Effect of Turmeric on Pruritus in Hemodialysis Patients
We'll reach out to this number within 24 hrs