Study to Assess Clearances and Bio-compatibility of ELISIO Dialyzer
Chronic Kidney Disease
About this trial
This is an interventional treatment trial for Chronic Kidney Disease focused on measuring solute clearances
Eligibility Criteria
Inclusion Criteria:
- 15 adult patients currently dialysing using the Fresenius FX100 dialyzer, who have used Fresenius polysulphone membranes for > 3 months, who are stable and able to provide informed consent.
Exclusion Criteria:
- using other dialyzers, unable to provide informed consent, unstable on dialysis or have problematical vascular access
Sites / Locations
- Royal Free Hospital
Arms of the Study
Arm 1
Experimental
dialyzer comparison
Stable chronic kidney dialysis patients, currently dialyzing on the main Royal Free hospital dialysis unit will be asked to participate in the study. It is aimed to recruit 15 patients currently dialysing using the Fresenius FX100 dialyzer, who have used Fresenius polysulphone membranes for > 3 months. During a mid week dialysis session, dialysis adequacy will be assessed by on line clearance, and samples of both blood and dialysate taken to assess, both clearances and bio-compatibility. Thereafter patients would be switched to dialyse using the ELISIOTM-H dialyzer, but continue with the same dialysis prescription, and after 3 months, measurements repeated