Left Atrial Ablation With Permanent Pacemaker or ImplanTable Loop Recorder Follow-UP (LAAPITUP)
Paroxysmal Atrial Fibrillation
About this trial
This is an interventional treatment trial for Paroxysmal Atrial Fibrillation focused on measuring Atrial Fibrillation, Atrial Fibrillation Ablation, Atrial Fibrillation monitoring, Ablation Frontiers, Reveal XT, LASSO
Eligibility Criteria
Inclusion Criteria:
- Patient aged 16-80 years old.
- Symptomatic PAF with AF episodes self terminating after at least 30 seconds but not longer than 24 hours. Preference is given to patients with AF episodes lasting no longer than 4 hours.
- PAF should have failed at least one drug therapy medical therapy.
- Patients must give written informed consent form prior to participating in this study.
Exclusion Criteria:
- Patient is suffering with unstable angina in last 1 week.
- Patient has had a myocardial infarction within last 2 months.
- Patient is expecting or has had major cardiac surgery within last 2 months.
- Patient is participating in a conflicting study.
- Patient is mentally incapacitated and cannot consent or comply with follow-up.
- Patient has NYHA class III/ IV heart failure.
- Patients with severe valvular or ventricular dysfunction.
- Pregnancy.
- Patient suffers with other cardiac rhythm disorders.
- Recent coronary artery intervention or other factors suggesting clinical instability (ECG, clinical or laboratory findings)
Sites / Locations
- Eastbourne District General Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Active Comparator
Active Comparator
Active Comparator
Active Comparator
Ablation Frontiers Ablation
LASSO ablation
Reveal XT monitoring
Permanent Pacemaker - dual chamber
This group will undergo AF ablation using Ablation Frontiers Technology.
This group will undergo atrial fibrillation ablation with traditional LASSO technology
This group will be monitored pre and post ablation using a Reveal XT implantable loop recorder.
This group will be monitored pre and post ablation with a dual chamber permanent pacemaker