A Comparison of Changes in Bone Density With the Same Bone-health Plan, But With Different Bone-health Supplements

A Comparison of Changes in Bone Density With the Same Bone-health Plan, But With Different Bone-health Supplements

Bone Mineral Density (BMD) Changes in a Bone Health Plan Using Two Versions of a Bone Health Supplement: A Comparative Effectiveness Research (CER) Study

A comparison of changes in bone density following the same bone-health plan, but with a different bone-health supplement.

The US Surgeon General's Report on Bone Health suggests America's bone-health is in jeopardy and issued a "call to action" to develop bone-health plans that: improve nutrition, increase health literacy and, increase physical activity. The purpose of this study was to use a comparative effective research model to compare 6-month changes in bone mineral density (BMD)in two study groups. Both followed the same bone health plan that contained the three components listed above with the same plant-source calcium supplement, but enhanced with different levels of calcium, vitamin D3, vitamin K and magnesium.

Measurements of bone mineral density were conducted at baseline and 6 months from baseline in two different study groups following the same bone-health behavior modification plan, but with different versions of a bone-health calcium supplement.

A comparison of changes from baseline in 43-blood chemistry panel and a self-reported quality of life inventory in both study groups

Study subjects in both arms of the study completed a fasting 43-blood chemistry panel and an 84-item self-reported quality of life inventory at baseline and again after participating in the study for six months. No significant differences were found in the within-group changes from baseline or between the groups on both sets of measures.

Inclusion Criteria: All subjects were required to contact the physicians to ensure they had no medical issues that would preclude their participation. Exclusion Criteria: Younger the 18 years of age, and Recommendations not to participate from their physicians.

Michalek JE, Preuss HG, Croft HA, Keith PL, Keith SC, Dapilmoto M, Perricone NV, Leckie RB, Kaats GR. Changes in total body bone mineral density following a common bone health plan with two versions of a unique bone health supplement: a comparative effectiveness research study. Nutr J. 2011 Apr 14;10:32. doi: 10.1186/1475-2891-10-32.