Hypercapnic Spontaneous Hyperpnoea and Recovery From Sevoflurane Anesthesia
Anesthesia, Surgery
About this trial
This is an interventional treatment trial for Anesthesia focused on measuring Isocapnic hyperpnoea (IH), Anesthesia, Accelerate elimination of inhalation agents, Recovery from anesthesia
Eligibility Criteria
Inclusion Criteria:
- elective gynecological surgery
- age 18-80
- ASA I-III
- informed consent
Exclusion Criteria:
- ASA IV-V,
- contra-indications to sevoflurane anesthesia or other anesthetics included in the protocol
- history of cardiac or respiratory disease
- intracranial pathology
- alcohol or drug abuse
- psychiatric illness and/or medications
Sites / Locations
- Toronto General Hospital, University Health Network
Arms of the Study
Arm 1
Arm 2
Other
Active Comparator
Control Arm
HSH Group
The O2 flow on the anesthetic machine will be set at 15 L/min. Ventilatory assistance will be performed to maintain O2 saturation >97% and end tidal CO2 at 35-45mmHg.
Patient will be disconnected from the anesthetic circuit and connected to the resuscitation bag attached to the IH system. With O2 flow of 2 L/min patient will be gently ventilated until recovery of the spontaneous ventilation. After starting spontaneous ventilation basal O2 flow will be adjusted to keep ETCO2 in range of 50-60 mm Hg or minute ventilation of 15-17 L/min, whichever occurs first.