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Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Ethiopia

Primary Purpose

Malaria, Mosquito Repellent, Long Lasting Insecticidal Nets

Status
Completed
Phase
Phase 4
Locations
Ethiopia
Study Type
Interventional
Intervention
Mosquito repellent
Sponsored by
Malaria Consortium, Ethiopia
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional prevention trial for Malaria focused on measuring Malaria, Mosquito repellent, LLINs

Eligibility Criteria

undefined - undefined (Child, Adult, Older Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

  • All volunteer household members

Exclusion Criteria:

  • Infants less than two months
  • Not in the study area

Sites / Locations

  • SNNPR, Ethiopia

Arms of the Study

Arm 1

Arm Type

Experimental

Arm Label

Mosquito repellent and LLINs group vs. LLINs group only

Arm Description

This study is based on two population groups: 1) a group of households that use LLINs alone (control) and 2) a group of households that use both mosquito repellent and LLINs (repellent group).

Outcomes

Primary Outcome Measures

Malaria parasite (P. falciparum and/or P. vivax)through microscopic detection
The objective of the study is to investigate the impact of a combined use of mosquito repellent and LLINs in reducing malaria. The primary outcome of the study is detection of malaria parasites (P. falciparum and/or P. vivax) through examination of microscopic blood slides collected from finger-pricks.

Secondary Outcome Measures

Household ownership and utilization of LLINs
Owneship and utilization of LLINs by household members during the night before the baseline survey

Full Information

First Posted
July 8, 2010
Last Updated
July 9, 2010
Sponsor
Malaria Consortium, Ethiopia
Collaborators
Addis Ababa University, Columbia University, Coalition Against Malaria in Ethiopia
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1. Study Identification

Unique Protocol Identification Number
NCT01160809
Brief Title
Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Ethiopia
Official Title
Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Southern Ethiopia: a Cluster-randomized Controlled Trial
Study Type
Interventional

2. Study Status

Record Verification Date
July 2010
Overall Recruitment Status
Completed
Study Start Date
September 2008 (undefined)
Primary Completion Date
December 2008 (Actual)
Study Completion Date
January 2009 (Actual)

3. Sponsor/Collaborators

Name of the Sponsor
Malaria Consortium, Ethiopia
Collaborators
Addis Ababa University, Columbia University, Coalition Against Malaria in Ethiopia

4. Oversight

Data Monitoring Committee
No

5. Study Description

Brief Summary
The combined use of a mosquito repellent and long lasting insecticidal nets (LLINs) by household members would result in a 40% reduction in malaria prevalence compared with households that only use LLINs.
Detailed Description
It has been recognized that the use of malaria preventive measures in combination with LLINs could improve the effectiveness of nets in preventing the disease. This study examined the effect of a combined use of mosquito repellent (i.e., Buzz Off) and LLINs on malaria prevalence in an area of unstable and seasonal malaria transmission.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Malaria, Mosquito Repellent, Long Lasting Insecticidal Nets
Keywords
Malaria, Mosquito repellent, LLINs

7. Study Design

Primary Purpose
Prevention
Study Phase
Phase 4
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
6082 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Mosquito repellent and LLINs group vs. LLINs group only
Arm Type
Experimental
Arm Description
This study is based on two population groups: 1) a group of households that use LLINs alone (control) and 2) a group of households that use both mosquito repellent and LLINs (repellent group).
Intervention Type
Other
Intervention Name(s)
Mosquito repellent
Intervention Description
Mosquito repellent (Buzz Off jelly) every evening applied to face, neck, hands and legs
Primary Outcome Measure Information:
Title
Malaria parasite (P. falciparum and/or P. vivax)through microscopic detection
Description
The objective of the study is to investigate the impact of a combined use of mosquito repellent and LLINs in reducing malaria. The primary outcome of the study is detection of malaria parasites (P. falciparum and/or P. vivax) through examination of microscopic blood slides collected from finger-pricks.
Secondary Outcome Measure Information:
Title
Household ownership and utilization of LLINs
Description
Owneship and utilization of LLINs by household members during the night before the baseline survey

10. Eligibility

Sex
All
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: All volunteer household members Exclusion Criteria: Infants less than two months Not in the study area
Facility Information:
Facility Name
SNNPR, Ethiopia
City
Awassa
State/Province
Snnpr
Country
Ethiopia

12. IPD Sharing Statement

Citations:
PubMed Identifier
24678612
Citation
Deressa W, Yihdego YY, Kebede Z, Batisso E, Tekalegne A, Dagne GA. Effect of combining mosquito repellent and insecticide treated net on malaria prevalence in Southern Ethiopia: a cluster-randomised trial. Parasit Vectors. 2014 Mar 28;7:132. doi: 10.1186/1756-3305-7-132.
Results Reference
derived

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Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Ethiopia

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