Back to resultsEffects of Pursed-lip Breathing on Exercise Tolerance and Dynamic Hyperinflation in COPD
Primary Purpose
Chronic Obstructive Pulmonary Disease
Status
Completed
Phase
Not Applicable
Locations
Brazil
Study Type
Interventional
Intervention
Pursed-lip breathing
Normal Breathing
Sponsored by
About this trial
This is an interventional treatment trial for Chronic Obstructive Pulmonary Disease focused on measuring exercise tolerance, dynamic hyperinflation, respiratory mechanics
Eligibility Criteria
Inclusion Criteria:
- Clinical diagnosis of chronic obstructive pulmonary disease (COPD)
- Regular treatment at Clementino Fraga Filho University Hospital (UFRJ)
Exclusion Criteria:
- Exacerbation in the preceding 4 weeks
- SpO2<85% at peak exercise
- Other diseases that may contribute to dyspnea and exercise intolerance
Sites / Locations
- Clementino Fraga Filho University Hospital
Arms of the Study
Arm 1
Arm Type
Experimental
Arm Label
Pursed-lip Breathing
Arm Description
Outcomes
Primary Outcome Measures
Endurance time
Secondary Outcome Measures
inspiratory capacity
oxygen saturation
dyspnea
forced oscillation variables
Full Information
NCT ID
NCT01173328
First Posted
July 19, 2010
Last Updated
July 30, 2010
Sponsor
Universidade Federal do Rio de Janeiro
1. Study Identification
Unique Protocol Identification Number
NCT01173328
Brief Title
Effects of Pursed-lip Breathing on Exercise Tolerance and Dynamic Hyperinflation in COPD
Official Title
Effects of Pursed-lip Breathing on Exercise Tolerance and Dynamic Hyperinflation in Chronic Obstructive Pulmonary Disease
Study Type
Interventional
2. Study Status
Record Verification Date
August 2008
Overall Recruitment Status
Completed
Study Start Date
March 2007 (undefined)
Primary Completion Date
October 2009 (Actual)
Study Completion Date
October 2009 (Actual)
3. Sponsor/Collaborators
Name of the Sponsor
Universidade Federal do Rio de Janeiro
4. Oversight
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
Pursed-lip breathing (PLB) has been advocated to reduce respiratory rate and improve oxygen saturation in patients with chronic obstructive pulmonary disease (COPD) at rest. Although PLB is a strategy that potentially reduces expiratory flow limitation, there are only few studies addressing its effects on exercise.
This study aimed to assess the ability of PLB to change the breathing pattern, degree of dynamic hyperinflation (DH) and arterial oxygenation in COPD patients during exercise. Exercise tolerance was evaluated by endurance time and respiratory mechanics was evaluated by forced oscillation technique.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Chronic Obstructive Pulmonary Disease
Keywords
exercise tolerance, dynamic hyperinflation, respiratory mechanics
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Crossover Assignment
Masking
Outcomes Assessor
Allocation
Randomized
Enrollment
40 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Pursed-lip Breathing
Arm Type
Experimental
Intervention Type
Behavioral
Intervention Name(s)
Pursed-lip breathing
Intervention Description
Pursed-lip breathing involves a nasal inspiration followed by expiratory blowing against partially closed lips, avoiding forceful exhalation.
Intervention Type
Behavioral
Intervention Name(s)
Normal Breathing
Primary Outcome Measure Information:
Title
Endurance time
Time Frame
within the first 01 hour
Secondary Outcome Measure Information:
Title
inspiratory capacity
Time Frame
within the first 01 hour
Title
oxygen saturation
Time Frame
within the first 01 hour
Title
dyspnea
Time Frame
within the first 01 hour
Title
forced oscillation variables
Time Frame
within the first 01 hour
10. Eligibility
Sex
All
Minimum Age & Unit of Time
40 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Clinical diagnosis of chronic obstructive pulmonary disease (COPD)
Regular treatment at Clementino Fraga Filho University Hospital (UFRJ)
Exclusion Criteria:
Exacerbation in the preceding 4 weeks
SpO2<85% at peak exercise
Other diseases that may contribute to dyspnea and exercise intolerance
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Fernando S Guimarães, PhD
Organizational Affiliation
Universidade Federal do Rio de Janeiro
Official's Role
Study Director
Facility Information:
Facility Name
Clementino Fraga Filho University Hospital
City
Rio de Janeiro
Country
Brazil
12. IPD Sharing Statement
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Effects of Pursed-lip Breathing on Exercise Tolerance and Dynamic Hyperinflation in COPD
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