Effect of Aqueous Extract of Garlic and Nystatin Mouthwash in Denture Stomatitis
Denture Stomatitis
About this trial
This is an interventional treatment trial for Denture Stomatitis focused on measuring denture stomatitis, nystatin, garlic
Eligibility Criteria
Inclusion Criteria:
- 40 years of age and older
- confirm of denture stomatitis by the oral medicine specialists
Exclusion Criteria:
- Patients with a history of using anti-fungal drugs, antibiotics, and corticosteroid within the previous month
- allergy to garlic and nystatin mouthwash
- immunodeficiency
- uncontrolled diabetes
- those with garlic rich diet
- inability in using mouthwash
- loose and discolored dentures
- psychologic disorder and alzheimer
Sites / Locations
- QUMS
Arms of the Study
Arm 1
Other
drug: garlic extract, nystatin
Drug: garlic extract 40mg/dl or nystatin suspension 100000 iu/ml tid for one month Patients had been clinically with denture stomatitis and confirmed by oral medicine specialist were selected for the study. Gender, age, medical history, erythema types, size, and other treatment used for this disease were recorded. Local ethical committee approval was obtained before the trial started and all patients gave written informed consent. Patients were randomly divided into two groups .First group received garlic extract and second group used nystatin suspension for 1 month. Each patients was examined at the beginning of the therapy ,and then every 1 weeks up to 1 months .