IRB-HSR# 14296 The Use of the Intrathoracic Pressure Regulator (ITPR) to Improve Systemic Blood Pressure in Patient Undergoing CABG Surgery
Coronary Artery Disease
About this trial
This is an interventional health services research trial for Coronary Artery Disease focused on measuring CABG surgery
Eligibility Criteria
Inclusion Criteria:
- 1. patients presenting for elective CABG with planned intraoperative TEE 2. age 18 years of age and older 3. informed consent has been obtained
Exclusion Criteria:
1. Patients with planned valve surgery (valve or CABG + valve) 2. patients with a contraindication to transesophageal echocardiography (TEE); including patients with extensive esophageal or gastric disease. Relative contraindications include esophageal varices, Barrett's esophagus, Zenker's diverticulum, and postradiation therapy of the esophageal area.
3. patients requiring IABP or VAD pre-operatively 4. emergent CABG 5. pneumothorax 6. hemothorax 7. uncontrolled bleeding 8. uncontrolled hypertension defined as SBP > 180 mmHg at the time of surgery
Sites / Locations
- University of Virginia Health System
Arms of the Study
Arm 1
Experimental
ITPR device
the ITPR will be inserted in the anesthesia circuit and activated to provide -10 mmHg ETP.