F-18 Sodium Fluoride in Prostate Cancer
Prostate Neoplasm
About this trial
This is an interventional diagnostic trial for Prostate Neoplasm focused on measuring Imaging, Bone Metastasis, Bone Scan, Radiopharmaceutical, Pet Scan, Prostate Cancer
Eligibility Criteria
- INCLUSION CRITERIA:
Participants must have a clinical course consistent with prostate cancer and have available documentation of prostate adenocarcinoma from either the National Cancer Institute (NCI) or from an outside pathology laboratory.
Participant must have:
- A history of PSA of > 10ng/mL or a history of PSA doubling time of less than or equal to 6 months, and no known bone metastatic involvement on standard of care imaging (Tc-99m MDP bone scan, CT etc)
OR
- Any PSA level and known bone metastatic disease on standard of care imaging (Tc-99m MDP bone scan, CT etc).
Ability to provide informed consent. All subjects must sign a document of informed consent indicating their understanding of the investigational nature and risks of the study before any protocol related studies are performed.
EXCLUSION CRITERIA:
Participants with severe claustrophobia unresponsive to oral anxiolytics.
Subjects weighing greater than 350 lbs (weight limit for scanner table), or unable to fit within the imaging gantry.
Subjects with any medical condition or other circumstances that, in the opinion of the Investigator, would significantly decrease obtaining reliable data, achieving study objectives or completing the study.
Sites / Locations
- National Institutes of Health Clinical Center, 9000 Rockville Pike
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Mets via NaF-18 PET/CT
No-Mets via NaF-18 PET/CT
Patients with known bone metastases (i.e. mets).
Patients with no clinical evidence of bone metastases