Back to resultsThe Association of G9a Protein and Outcome of Patients With Endometrial Cancer
Primary Purpose
Outcome of Endometrial Cancer
Status
Completed
Phase
Not Applicable
Locations
Taiwan
Study Type
Interventional
Intervention
no drug
Sponsored by
About this trial
This is an interventional basic science trial for Outcome of Endometrial Cancer
Eligibility Criteria
Inclusion Criteria:
- all cases with endometrial cancer underwent staging operation
Exclusion Criteria:
- nil
Sites / Locations
- Department of Obstetrics and Gynecology, Far-Eastern Memorial Hospital
Arms of the Study
Arm 1
Arm Type
No Intervention
Arm Label
endometrial cancer
Arm Description
Outcomes
Primary Outcome Measures
The role of G9a protein in endometrial cancer
We will correlate the G9a protein and outcome of endometrial cancer
Secondary Outcome Measures
Full Information
NCT ID
NCT01271764
First Posted
January 5, 2011
Last Updated
September 25, 2012
Sponsor
Far Eastern Memorial Hospital
1. Study Identification
Unique Protocol Identification Number
NCT01271764
Brief Title
The Association of G9a Protein and Outcome of Patients With Endometrial Cancer
Study Type
Interventional
2. Study Status
Record Verification Date
September 2012
Overall Recruitment Status
Completed
Study Start Date
January 2011 (undefined)
Primary Completion Date
July 2012 (Actual)
Study Completion Date
September 2012 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Far Eastern Memorial Hospital
4. Oversight
5. Study Description
Brief Summary
Tumor invasion and metastasis are the major causes of cancer-related death. Some studies have found that histone methyltransferases, such as EZH2, specifically affect metastasis in breast, gastric and prostate cancer. The functional roles of other members of the HMT family such as G9a in cancer remain obscure. Therefore, the investigators will investigate whether G9a have a role in recurrence/metastasis of endometrial cancer.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Outcome of Endometrial Cancer
7. Study Design
Primary Purpose
Basic Science
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
97 (Actual)
8. Arms, Groups, and Interventions
Arm Title
endometrial cancer
Arm Type
No Intervention
Intervention Type
Other
Intervention Name(s)
no drug
Intervention Description
The role of G9a protein in patients with endometrial cancer
Primary Outcome Measure Information:
Title
The role of G9a protein in endometrial cancer
Description
We will correlate the G9a protein and outcome of endometrial cancer
Time Frame
overall survial, disease-free survival
10. Eligibility
Sex
Female
Minimum Age & Unit of Time
20 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
all cases with endometrial cancer underwent staging operation
Exclusion Criteria:
nil
Facility Information:
Facility Name
Department of Obstetrics and Gynecology, Far-Eastern Memorial Hospital
City
Banqiao
State/Province
New Taipei
ZIP/Postal Code
22050
Country
Taiwan
12. IPD Sharing Statement
Learn more about this trial
The Association of G9a Protein and Outcome of Patients With Endometrial Cancer
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