The Effects of Dexlansoprazole for the Treatment of Throat-Related Reflux
Laryngopharyngeal Reflux
About this trial
This is an interventional treatment trial for Laryngopharyngeal Reflux focused on measuring laryngopharyngeal reflux, acid reflux, throat reflux
Eligibility Criteria
Inclusion Criteria:patients with an abnormal Restech pH probe study and also have an RSI of 14 or greater will be invited to participate in the study
Exclusion Criteria:known intolerance or allergy to proton pump inhibitors, hypersecretory conditions (Zollinger-Ellison), self-reported anxiety/depression (shown to affect RSI),16 history of laryngeal irradiation, or have been on twice daily Proton pump inhibitors (PPI) therapy for greater than 2 months without symptomatic relief (with an RSI ≥14)
Sites / Locations
- Clarian North Hospital -- IUMG Clinic
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Dexlansoprazole
Sugar pill
Patients who agree to participate in the study will be randomized to receive 60 mg po QAM Kapidex (1 hour AC).
Patients who agree to participate in the study will be randomized to receive 60 mg po QAM Kapidex (1 hour AC) or 1 tablet of placebo QAM (1 hour AC).