Light Sensitization Study
Chronobiology Disorders, Circadian Rhythm Disorders, Sleep Disorders, Circadian Rhythm
About this trial
This is an interventional basic science trial for Chronobiology Disorders focused on measuring light, melatonin, circadian, delayed sleep phase disorder, circadian light sensitivity, circadian timing system
Eligibility Criteria
Inclusion Criteria:
- healthy adults with conventional and regular sleep-wake timing
- non-smokers
- completion of medical, psychological, ophthalmological, and sleep screening tests
- able to spend 13 consecutive days/nights in the laboratory
Exclusion Criteria:
- history of neurological or psychiatric disorder
- history of eye injury, eye surgery, or visual disorder (corrective lenses are acceptable)
- history of sleep disorder or regular use of sleep-promoting medication
- current prescription, herbal, or over-the-counter medication use (oral contraceptives are acceptable)
Sites / Locations
- Brigham and Women's Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Experimental
Experimental
Experimental
sensitization duration 1.375h
sensitization duration 5.5h
sensitization duration 22h
sensitization duration 0.33h
This group will experience a 1.375h sensitization duration prior to the 12h light exposure
This group will experience a 5.5h sensitization duration prior to the 12h light exposure
This group will experience a 22h sensitization duration prior to the 12h light exposure
This group will experience a 0.33h sensitization duration prior to the 12h light exposure