Use of Chamomilla Recutita in Mucositis
Mucositis
About this trial
This is an interventional treatment trial for Mucositis focused on measuring mucositis, chamomilla, therapeutics
Eligibility Criteria
Inclusion Criteria:
- subjects over 18 years of age;
- candidates for allogeneic HSCT;
- with intact oral cavity on the first day of conditioning.
Exclusion Criteria:
- present any adverse reaction to the active principles of Chamomilla recutita;
- receive oral or intravenous anticoagulation therapy;
- use oral or systemic topical anti-inflammatory medication;
- receive any other type of intervention for mucositis not included in the standard oral care protocol.
Sites / Locations
- Hospital Amaral Carvalho
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Experimental
Active Comparator
Experimental
mouthwash with Chamomilla extract 1%
mouthwash with Chamomilla extract 2%
standard oral care protocol
mouthwash with Chamomilla extract 0.5%
The Chamomile recutita mouthwash 1% was administered two times daily for 30 days.
The Chamomile recutita mouthwash 2% was administered two times daily for 30 days.
The standard protocol at the unit, which comprises mouthwash with chlorhexidine 0,12%; oral hygiene teaching. In case the toothbrush cannot be used due to gingival or oral mucosa bleeding, gauze is used to replace it.
The Chamomile recutita mouthwash 0.5% was administered two times daily for 30 days, starting on the first day of chemotherapy.