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Chemotherapy Toxicity On Quality of Life in Older Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer

Primary Purpose

Stage I Ovarian Cancer AJCC v6 and v7, Stage IA Fallopian Tube Cancer AJCC v6 and v7, Stage IB Fallopian Tube Cancer AJCC v6 and v7

Status

Unknown status

Phase

Locations

United States

Study Type

Observational

Intervention

Assessment of Therapy Complications

Carboplatin

Filgrastim

Paclitaxel

Pharmacological Study

Quality-of-Life Assessment

Questionnaire Administration

About this trial

This is an observational trial for Stage I Ovarian Cancer AJCC v6 and v7

Eligibility Criteria

75 Years - undefined (Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

Eligible patients must have a histologically or cytologically confirmed diagnosis of adenocarcinoma of the ovary, peritoneum, or fallopian tube either by surgery, biopsy, fine-needle aspiration (FNA), paracentesis, or thoracentesis; a diagnosis of a mucinous cancer must be made by biopsy only
International Federation of Gynecology and Obstetrics (FIGO) stage I, II, III, and IV are eligible
Patients must have received no previous treatment for this malignancy other than surgery
Patients must be entered within eight weeks of confirmation of disease diagnosis by surgery, biopsy, FNA, paracentesis or thoracentesis if there is no primary surgery, and within twelve weeks of primary or staging surgery if patient received primary surgery
Absolute neutrophil count (ANC) greater than or equal to 1,500/mcl
Platelets greater than or equal to 100,000/mcl
Bilirubin less than or equal upper limit of normal (ULN)
Creatinine less than or equal to 1.5 x ULN
Patients must have a Gynecologic Oncology Group (GOG) performance status of 0, 1, 2 or 3
Effective XX/XX/2014, only patients 75 years of age or older are eligible for enrollment; (04/23/2012) (08/12/2013)
Patients must have recovered from the effects of recent surgery
Patients must be free of active infection requiring antibiotics
Patients must have signed an approved informed consent and Health Insurance Portability and Accountability Act (HIPAA)
Patient and physician agree that they plan to conduct treatment according to Regimen 3
Patient can read and understand sufficient English to be able to respond to questions posed by the study instruments

Exclusion Criteria:

Patients who have received previous treatment for this malignancy other than surgery
Patients with other invasive malignancies whose previous cancer treatment contraindicates this protocol therapy
?Borderline tumors? (tumors of low malignant potential) by surgery or biopsy are excluded
Patients with medical conditions that in the opinion of the investigator render treatment on this protocol unsafe should be excluded

Sites / Locations

University of Alabama at Birmingham Cancer Center
Gynecologic Oncology Group of Arizona
Saint Joseph's Hospital and Medical Center
Mayo Clinic Hospital in Arizona
Mayo Clinic in Arizona
University of Arizona Cancer Center-North Campus
John Muir Medical Center-Concord Campus
UC San Diego Moores Cancer Center
Palo Alto Medical Foundation-Gynecologic Oncology
Saint Joseph Hospital - Orange
UC Irvine Health/Chao Family Comprehensive Cancer Center
Stanford Cancer Institute Palo Alto
UCSF Medical Center-Mount Zion
Olive View-University of California Los Angeles Medical Center
Rocky Mountain Gynecologic Oncology PC
Danbury Hospital
Hartford Hospital
Smilow Cancer Hospital Care Center at Saint Francis
Middlesex Hospital
The Hospital of Central Connecticut
Yale University
Stamford Hospital/Bennett Cancer Center
Beebe Medical Center
Christiana Gynecologic Oncology LLC
Delaware Clinical and Laboratory Physicians PA
Helen F Graham Cancer Center
Medical Oncology Hematology Consultants PA
Christiana Care Health System-Christiana Hospital
Beebe Health Campus
Christiana Care Health System-Wilmington Hospital
Holy Cross Hospital
Florida Gynecologic Oncology
Jupiter Medical Center
Mount Sinai Medical Center
Mercy Hospital
Sarasota Memorial Hospital
Moffitt Cancer Center
Augusta University Medical Center
John B Amos Cancer Center
Dekalb Medical Center
Northeast Georgia Medical Center-Gainesville
Memorial Health University Medical Center
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
Saint Alphonsus Cancer Care Center-Boise
Northwestern University
University of Chicago Comprehensive Cancer Center
Weiss Memorial Hospital
Sudarshan K Sharma MD Limited-Gynecologic Oncology
Good Samaritan Regional Health Center
West Suburban Medical Center
Northwestern Medicine Cancer Center Warrenville
Franciscan Saint Francis Health-Beech Grove
Elkhart Clinic
Michiana Hematology Oncology PC-Elkhart
Elkhart General Hospital
Franciscan Health Indianapolis
Saint Vincent Hospital and Health Care Center
Community Howard Regional Health
IU Health La Porte Hospital
Cancer Care Partners LLC
Michiana Hematology Oncology PC-Mishawaka
Saint Joseph Regional Medical Center-Mishawaka
Michiana Hematology Oncology PC-Plymouth
Reid Health
Memorial Hospital of South Bend
Michiana Hematology Oncology PC-South Bend
South Bend Clinic
Northern Indiana Cancer Research Consortium
Michiana Hematology Oncology PC-Westville
Mary Greeley Medical Center
McFarland Clinic PC - Ames
McFarland Clinic PC-Boone
Mercy Hospital
Oncology Associates at Mercy Medical Center
Medical Oncology and Hematology Associates-West Des Moines
Mercy Cancer Center-West Lakes
Iowa Methodist Medical Center
Iowa-Wide Oncology Research Coalition NCORP
Medical Oncology and Hematology Associates-Des Moines
Medical Oncology and Hematology Associates-Laurel
Mercy Medical Center - Des Moines
Iowa Lutheran Hospital
University of Iowa/Holden Comprehensive Cancer Center
McFarland Clinic PC-Jefferson
McFarland Clinic PC-Marshalltown
Siouxland Regional Cancer Center
Mercy Medical Center-Sioux City
Saint Luke's Regional Medical Center
Methodist West Hospital
Mercy Medical Center-West Lakes
Cancer Center of Kansas - Chanute
Cancer Center of Kansas - Dodge City
Cancer Center of Kansas - El Dorado
Cancer Center of Kansas - Fort Scott
Cancer Center of Kansas-Independence
Providence Medical Center
Cancer Center of Kansas-Kingman
Lawrence Memorial Hospital
Cancer Center of Kansas-Liberal
Cancer Center of Kansas-Manhattan
Cancer Center of Kansas - McPherson
Cancer Center of Kansas - Newton
Menorah Medical Center
Saint Luke's South Hospital
Cancer Center of Kansas - Parsons
Kansas City NCI Community Oncology Research Program
Cancer Center of Kansas - Pratt
Cancer Center of Kansas - Salina
Cotton O'Neil Cancer Center / Stormont Vail Health
Cancer Center of Kansas - Wellington
Associates In Womens Health
Cancer Center of Kansas-Wichita Medical Arts Tower
Ascension Via Christi Hospitals Wichita
Cancer Center of Kansas - Wichita
Wichita NCI Community Oncology Research Program
Cancer Center of Kansas - Winfield
Oncology Hematology Care Inc-Crestview
Saint Elizabeth Medical Center South
Baptist Health Lexington
Norton Hospital Pavilion and Medical Campus
Woman's Hospital
Tulane University Health Sciences Center
Ochsner Medical Center Jefferson
Harold Alfond Center for Cancer Care
Eastern Maine Medical Center
Maine Medical Center-Bramhall Campus
University of Maryland/Greenebaum Cancer Center
Greater Baltimore Medical Center
Christiana Care - Union Hospital
Boston Medical Center
Lahey Hospital and Medical Center
Beth Israel Deaconess Hospital-Plymouth
UMass Memorial Medical Center - Memorial Division
Michigan Cancer Research Consortium NCORP
Saint Joseph Mercy Hospital
Beaumont Hospital - Dearborn
Wayne State University/Karmanos Cancer Institute
Henry Ford Hospital
Ascension Saint John Hospital
Green Bay Oncology - Escanaba
Genesys Hurley Cancer Institute
Hurley Medical Center
Genesys Regional Medical Center-West Flint Campus
Genesys Regional Medical Center
Green Bay Oncology - Iron Mountain
Allegiance Health
Bronson Methodist Hospital
West Michigan Cancer Center
Borgess Medical Center
Sparrow Hospital
Saint Mary Mercy Hospital
Saint Joseph Mercy Oakland
Lake Huron Medical Center
William Beaumont Hospital-Royal Oak
Ascension Saint Mary's Hospital
Lakeland Medical Center Saint Joseph
Marie Yeager Cancer Center
Ascension Providence Hospitals - Southfield
William Beaumont Hospital - Troy
Saint John Macomb-Oakland Hospital
Sanford Joe Lueken Cancer Center
Fairview Ridges Hospital
Mercy Hospital
Fairview Southdale Hospital
Unity Hospital
Hutchinson Area Health Care
Minnesota Oncology Hematology PA-Maplewood
Saint John's Hospital - Healtheast
Abbott-Northwestern Hospital
Hennepin County Medical Center
University of Minnesota/Masonic Cancer Center
New Ulm Medical Center
North Memorial Medical Health Center
Mayo Clinic in Rochester
Metro Minnesota Community Oncology Research Consortium
Park Nicollet Clinic - Saint Louis Park
Park Nicollet Frauenshuh Cancer Center
Regions Hospital
United Hospital
Saint Francis Regional Medical Center
Lakeview Hospital
Ridgeview Medical Center
Rice Memorial Hospital
Minnesota Oncology Hematology PA-Woodbury
Saint Luke's Hospital of Kansas City
North Kansas City Hospital
Heartland Hematology and Oncology Associates Incorporated
Research Medical Center
Saint Luke's East - Lee's Summit
Liberty Radiation Oncology Center
Mercy Clinic-Rolla-Cancer and Hematology
Heartland Regional Medical Center
Saint Joseph Oncology Inc
Washington University School of Medicine
Cancer Research for the Ozarks NCORP
Mercy Hospital Springfield
CoxHealth South Hospital
Billings Clinic Cancer Center
Saint Vincent Healthcare
Montana Cancer Consortium NCORP
Saint Vincent Frontier Cancer Center
Bozeman Deaconess Hospital
Saint James Community Hospital and Cancer Treatment Center
Benefis Healthcare- Sletten Cancer Institute
Great Falls Clinic
Northern Montana Hospital
Saint Peter's Community Hospital
Glacier Oncology PLLC
Kalispell Medical Oncology
Kalispell Regional Medical Center
Montana Cancer Specialists
Saint Patrick Hospital - Community Hospital
CHI Health Good Samaritan
Nebraska Methodist Hospital
Women's Cancer Center of Nevada
Cooper Hospital University Medical Center
Hackensack University Medical Center
Virtua Memorial
Rutgers New Jersey Medical School
Virtua Voorhees
University of New Mexico Cancer Center
Southwest Gynecologic Oncology Associates Inc
Women's Cancer Care Associates LLC
State University of New York Downstate Medical Center
Roswell Park Cancer Institute
Glens Falls Hospital
Northwell Health/Center for Advanced Medicine
North Shore University Hospital
Long Island Jewish Medical Center
Laura and Isaac Perlmutter Cancer Center at NYU Langone
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
Memorial Sloan Kettering Cancer Center
Stony Brook University Medical Center
State University of New York Upstate Medical University
Cone Health Cancer Center at Alamance Regional
UNC Lineberger Comprehensive Cancer Center
Carolinas Medical Center/Levine Cancer Institute
Novant Health Presbyterian Medical Center
Atrium Health Cabarrus/LCI-Concord
Duke University Medical Center
Wayne Memorial Hospital
Duke Raleigh Hospital
Wake Forest University Health Sciences
Mid Dakota Clinic
Saint Alexius Medical Center
Sanford Bismarck Medical Center
Sanford Broadway Medical Center
Sanford Clinic North-Fargo
Sanford Roger Maris Cancer Center
Summa Health System - Akron Campus
Cleveland Clinic Akron General
Strecker Cancer Center-Belpre
Aultman Health Foundation
Adena Regional Medical Center
Oncology Hematology Care Inc-Eden Park
Oncology Hematology Care Inc-Mercy West
Good Samaritan Hospital - Cincinnati
Oncology Hematology Care Inc-Anderson
Oncology Hematology Care Inc-Kenwood
Bethesda North Hospital
Oncology Hematology Care Inc-Blue Ash
Case Western Reserve University
MetroHealth Medical Center
Cleveland Clinic Cancer Center/Fairview Hospital
Cleveland Clinic Foundation
Ohio State University Comprehensive Cancer Center
Mount Carmel East Hospital
Columbus Oncology and Hematology Associates Inc
Riverside Methodist Hospital
Columbus NCI Community Oncology Research Program
Grant Medical Center
The Mark H Zangmeister Center
Mount Carmel Health Center West
Doctors Hospital
Grandview Hospital
Good Samaritan Hospital - Dayton
Miami Valley Hospital
Miami Valley Hospital North
Dayton NCI Community Oncology Research Program
Delaware Health Center-Grady Cancer Center
Delaware Radiation Oncology
Grady Memorial Hospital
Oncology Hematology Care Inc-Healthplex
Blanchard Valley Hospital
Atrium Medical Center-Middletown Regional Hospital
Wayne Hospital
Fairfield Medical Center
Lancaster Radiation Oncology
Marietta Memorial Hospital
Hillcrest Hospital Cancer Center
UH Seidman Cancer Center at Lake Health Mentor Campus
Knox Community Hospital
Licking Memorial Hospital
Newark Radiation Oncology
Southern Ohio Medical Center
Springfield Regional Medical Center
Upper Valley Medical Center
Saint Ann's Hospital
Greene Memorial Hospital
Genesis Healthcare System Cancer Care Center
University of Oklahoma Health Sciences Center
Natalie Warren Bryant Cancer Center at Saint Francis
Warren Clinic-Tulsa South
Oklahoma Cancer Specialists and Research Institute-Tulsa
Warren Clinic Oncology-Tulsa
Saint Luke's University Hospital-Bethlehem Campus
Adams Cancer Center
Cherry Tree Cancer Center
Thomas Jefferson University Hospital
Fox Chase Cancer Center
Temple University Hospital
University of Pittsburgh Cancer Institute (UPCI)
Guthrie Medical Group PC-Robert Packer Hospital
Chester County Hospital
Reading Hospital
WellSpan Health-York Hospital
Women and Infants Hospital
Sanford Cancer Center Oncology Clinic
Avera Cancer Institute
Sanford USD Medical Center - Sioux Falls
University of Tennessee - Knoxville
M D Anderson Cancer Center
Scott and White Memorial Hospital
University of Vermont Medical Center
Carilion Clinic Gynecological Oncology
Monongalia Hospital
Marshfield Clinic Cancer Center at Sacred Heart
Green Bay Oncology at Saint Vincent Hospital
Saint Vincent Hospital Cancer Center Green Bay
Green Bay Oncology Limited at Saint Mary's Hospital
Saint Vincent Hospital Cancer Center at Saint Mary's
Gundersen Lutheran Medical Center
University of Wisconsin Hospital and Clinics
Holy Family Memorial Hospital
Bay Area Medical Center
Marshfield Medical Center-Marshfield
Aurora Saint Luke's Medical Center
Medical College of Wisconsin
Marshfield Clinic-Minocqua Center
ProHealth D N Greenwald Center
Cancer Center of Western Wisconsin
ProHealth Oconomowoc Memorial Hospital
Saint Vincent Hospital Cancer Center at Oconto Falls
Vince Lombardi Cancer Clinic - Oshkosh
Ascension Saint Mary's Hospital
Marshfield Medical Center-Rice Lake
Vince Lombardi Cancer Clinic-Sheboygan
Ascension Saint Michael's Hospital
Green Bay Oncology - Sturgeon Bay
Aurora Medical Center in Summit
ProHealth Waukesha Memorial Hospital
Marshfield Clinic-Wausau Center
Aurora West Allis Medical Center
Marshfield Medical Center - Weston
Marshfield Clinic - Wisconsin Rapids Center
Rocky Mountain Oncology
Welch Cancer Center

Arms of the Study

Arm 1

Arm Type

Arm Label

Observational (quality of life questionnaire)

Arm Description

Patients receive chemotherapy comprising carboplatin, paclitaxel, and filgrastim (regimen 1) or carboplatin alone (regimen 2) every 21 days for 4 courses according to their physicians and/or patients' choice. Patients may undergo surgery and/or further chemotherapy at the discretion of treating physician. Patients undergo blood sample collection at baseline and periodically during course 1 for pharmacokinetic studies. Patients' quality of life is assessed by the FACT-O, the FACT-Ntx subscale, the IADL, and the Ability to Complete Social Activity questionnaires at baseline, prior to courses 1 and 3, and then 3-6 weeks after completion of course 4. Nutritional status, such as body mass index and weight loss, and comorbidity and hearing impairment are also assessed.

Outcomes

Primary Outcome Measures

Tolerance to study treatment, defined as completing four cycles of study treatment, without dose reductions or treatment delays of over seven days

Will be modeled with logistic regression using baseline IADL scores as a covariate. Exploratory analysis will evaluate baseline IADL scores adjusting for covariates such as: Charlson scale, nutritional status, or age.

Percent of women, who are 70 years or older, able to complete at least 4 cycles of treatment regardless of dose reduction and delays

While this percentage will be estimated for each study regimen separately, the targeted sample size will limit the width of the 95%-confidence interval for the marginal percentage so that it is no larger than 0.15.

Secondary Outcome Measures

Changes in quality-of-life measured by FACT-O, FACT/GOG-Ntx-4 subscale, IADL, and ADL

The changes in FACT-O, FACT/GOG-Ntx-4 subscale, IADL, and ADL will be summarized descriptively as the differences of scores between pre and post chemotherapy. Assuming 80% of patients complete the assessment at the completion of chemotherapy, then a sample of 148 patients will provide 90% power to detect 5 unit changes in FACT-O, 0.5 unit change in FACT/GOG-Ntx subscale score, 1 unit change in IADL or ADL score using paired t-test at significant level of 0.05.

Changes in comorbidity index measured by the Charlson scale

Changes in nutritional status measured by weight

The changes in weight will be summarized descriptively as the differences of scores between pre and post chemotherapy. The change of nutritional status after completing chemotherapy will be examined using McNemar?s test.

Clinical response of elderly patients with ovarian, primary peritoneal cavity, or fallopian tube cancer

Percent of patients reporting adverse events as assessed by the National Cancer Institute's Common Terminology Criteria for Adverse Events

The probability of an adverse event will be estimated as the percent of patients reporting an adverse event out of all patients beginning treatment.

Full Information

NCT ID

NCT01366183

First Posted

June 2, 2011

Last Updated

September 28, 2021

Sponsor

Gynecologic Oncology Group

Collaborators

National Cancer Institute (NCI)

1. Study Identification

Unique Protocol Identification Number

NCT01366183

Brief Title

Chemotherapy Toxicity On Quality of Life in Older Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer

Official Title

Chemotherapy Toxicity in Elderly Women With Ovarian, Primary Peritoneal or Fallopian Tube Cancer

Study Type

Observational

2. Study Status

Record Verification Date

September 2021

Overall Recruitment Status

Unknown status

Study Start Date

August 15, 2011 (Actual)

Primary Completion Date

December 31, 2021 (Anticipated)

Study Completion Date

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3. Sponsor/Collaborators

Responsible Party, by Official Title

Sponsor

Name of the Sponsor

Gynecologic Oncology Group

Collaborators

National Cancer Institute (NCI)

4. Oversight

Data Monitoring Committee

5. Study Description

Brief Summary

This trial studies the chemotherapy toxicity on quality of life in older patients with stage I, stage II, stage III, or stage IV ovarian epithelial, primary peritoneal cavity, or fallopian tube cancer. Learning about the side effects of chemotherapy in older patients may help doctors plan better ways to treat cancer.

Detailed Description

PRIMARY OBJECTIVES: l. To determine whether the score on Instrumental Activities of Daily Living (IADL) obtained prior to treatment is associated with the ability of patients to complete four cycles of chemotherapy without dose reduction or a more than 7-day delay. II. To estimate by regimen the percentage of patients who are able to complete four cycles of chemotherapy regardless of dose reductions and delays. III. To compare actual and calculated carboplatin area under the curve (AUC) in this patient population. SECONDARY OBJECTIVES: I. To describe the percentage of patients who are entered after primary surgery versus those entered to receive primary or neoadjuvant chemotherapy, the percentage of patients who are treated with each allowed regimen, and the percentage of patients who eventually receive surgery in the primary chemotherapy group. II. To determine whether the need for assistance with IADLs at time of registration is associated with choice of chemotherapy regimen (in both primary chemotherapy and primary surgery patients). III. To explore whether age, baseline scores on the geriatric measures (functional status, nutritional status, or co-morbidity) and quality-of-life (QOL) are correlated with likelihood of completing four courses of chemotherapy without dose reduction or a more than 7-day delay. IV. To explore reasons for and timing of dose reductions and delays. V. To describe toxicities, pre-/post-chemotherapy QOL, and pre-/post-chemotherapy scores on geriatric measures in this patient population. TERTIARY OBJECTIVES: I. To explore potential relationships of carboplatin AUC, paclitaxel clearance, and paclitaxel time above a plasma concentration of 0.05 mcM to nadir neutrophil and platelet counts during course 1 of treatment. II. To explore the association between baseline IADL and survival. III. To explore the association between IADL and the functional well-being (FWB) subscale in the Functional Assessment of Cancer Therapy ? Ovary (FACT-O). OUTLINE: Patients receive chemotherapy comprising carboplatin, paclitaxel, and filgrastim (regimen 1) or carboplatin alone (regimen 2) every 21 days for 4 courses according to their physicians and/or patients' choice. Patients may undergo surgery and/or further chemotherapy at the discretion of treating physician. Patients undergo blood sample collection at baseline and periodically during course 1 for pharmacokinetic studies. Patients' quality of life is assessed by the FACT-O, the Functional Assessment of Cancer Treatment ? Neurotoxicity (FACT-Ntx subscale), the IADL, and the Ability to Complete Social Activity questionnaires at baseline, prior to courses 1 and 3, and then 3-6 weeks after completion of course 4. Nutritional status, such as body mass index and weight loss, and comorbidity and hearing impairment are also assessed.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study

Stage I Ovarian Cancer AJCC v6 and v7, Stage IA Fallopian Tube Cancer AJCC v6 and v7, Stage IB Fallopian Tube Cancer AJCC v6 and v7, Stage IC Fallopian Tube Cancer AJCC v6 and v7, Stage II Ovarian Cancer AJCC v6 and v7, Stage IIA Fallopian Tube Cancer AJCC v6 and v7, Stage IIB Fallopian Tube Cancer AJCC v6 and v7, Stage IIC Fallopian Tube Cancer AJCC v6 and v7, Stage III Ovarian Cancer AJCC v6 and v7, Stage III Primary Peritoneal Cancer AJCC v7, Stage IIIA Fallopian Tube Cancer AJCC v7, Stage IIIB Fallopian Tube Cancer AJCC v7, Stage IIIC Fallopian Tube Cancer AJCC v7, Stage IV Fallopian Tube Cancer AJCC v6 and v7, Stage IV Ovarian Cancer AJCC v6 and v7, Stage IV Primary Peritoneal Cancer AJCC v7

7. Study Design

Enrollment

290 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title

Observational (quality of life questionnaire)

Arm Description

Intervention Type

Procedure

Intervention Name(s)

Assessment of Therapy Complications

Intervention Description

Undergo nutritional status, such as body mass index and weight loss, and comorbidity and hearing impairment assessments

Intervention Type

Drug

Intervention Name(s)

Carboplatin

Other Intervention Name(s)

Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo

Intervention Description

Undergo chemotherapy

Intervention Type

Biological

Intervention Name(s)

Filgrastim

Other Intervention Name(s)

FILGRASTIM, LICENSE HOLDER UNSPECIFIED, G-CSF, Neupogen, r-metHuG-CSF, Recombinant Methionyl Human Granulocyte Colony Stimulating Factor, rG-CSF, Tevagrastim

Intervention Description

Undergo chemotherapy

Intervention Type

Drug

Intervention Name(s)

Paclitaxel

Other Intervention Name(s)

Anzatax, Asotax, Bristaxol, Praxel, Taxol, Taxol Konzentrat

Intervention Description

Undergo chemotherapy

Intervention Type

Other

Intervention Name(s)

Pharmacological Study

Intervention Description

Correlative studies

Intervention Type

Other

Intervention Name(s)

Quality-of-Life Assessment

Other Intervention Name(s)

Quality of Life Assessment

Intervention Description

Ancillary studies

Intervention Type

Other

Intervention Name(s)

Questionnaire Administration

Intervention Description

Ancillary studies

Primary Outcome Measure Information:

Title

Tolerance to study treatment, defined as completing four cycles of study treatment, without dose reductions or treatment delays of over seven days

Description

Time Frame

Up to 5 years

Title

Percent of women, who are 70 years or older, able to complete at least 4 cycles of treatment regardless of dose reduction and delays

Description

Time Frame

Up to 5 years

Secondary Outcome Measure Information:

Title

Changes in quality-of-life measured by FACT-O, FACT/GOG-Ntx-4 subscale, IADL, and ADL

Description

Time Frame

Baseline to up to 6 weeks after completion of course 4

Title

Changes in comorbidity index measured by the Charlson scale

Time Frame

Baseline to up to 6 weeks after completion of course 4

Title

Changes in nutritional status measured by weight

Description

Time Frame

Baseline to up to 6 weeks after completion of course 4

Title

Clinical response of elderly patients with ovarian, primary peritoneal cavity, or fallopian tube cancer

Time Frame

Up to 5 years

Title

Percent of patients reporting adverse events as assessed by the National Cancer Institute's Common Terminology Criteria for Adverse Events

Description

The probability of an adverse event will be estimated as the percent of patients reporting an adverse event out of all patients beginning treatment.

Time Frame

Up to 6 weeks after course 4

Other Pre-specified Outcome Measures:

Title

Pharmacokinetic parameters including paclitaxel AUC, carboplatin AUC, paclitaxel total body clearance, and time that plasma paclitaxel concentration remains above threshold 0.05 uM/L

Description

The observed pharmacokinetics of paclitaxel and carboplatin will be compared with published pharmacokinetic measures of paclitaxel and carboplatin in a descriptive fashion. No formal statistical testing will be performed for the comparisons.

Time Frame

Pre-dose, 1, 6, and 24 hours

10. Eligibility

Sex

All

Minimum Age & Unit of Time

75 Years

Accepts Healthy Volunteers

Eligibility Criteria

Inclusion Criteria: Eligible patients must have a histologically or cytologically confirmed diagnosis of adenocarcinoma of the ovary, peritoneum, or fallopian tube either by surgery, biopsy, fine-needle aspiration (FNA), paracentesis, or thoracentesis; a diagnosis of a mucinous cancer must be made by biopsy only International Federation of Gynecology and Obstetrics (FIGO) stage I, II, III, and IV are eligible Patients must have received no previous treatment for this malignancy other than surgery Patients must be entered within eight weeks of confirmation of disease diagnosis by surgery, biopsy, FNA, paracentesis or thoracentesis if there is no primary surgery, and within twelve weeks of primary or staging surgery if patient received primary surgery Absolute neutrophil count (ANC) greater than or equal to 1,500/mcl Platelets greater than or equal to 100,000/mcl Bilirubin less than or equal upper limit of normal (ULN) Creatinine less than or equal to 1.5 x ULN Patients must have a Gynecologic Oncology Group (GOG) performance status of 0, 1, 2 or 3 Effective XX/XX/2014, only patients 75 years of age or older are eligible for enrollment; (04/23/2012) (08/12/2013) Patients must have recovered from the effects of recent surgery Patients must be free of active infection requiring antibiotics Patients must have signed an approved informed consent and Health Insurance Portability and Accountability Act (HIPAA) Patient and physician agree that they plan to conduct treatment according to Regimen 3 Patient can read and understand sufficient English to be able to respond to questions posed by the study instruments Exclusion Criteria: Patients who have received previous treatment for this malignancy other than surgery Patients with other invasive malignancies whose previous cancer treatment contraindicates this protocol therapy ?Borderline tumors? (tumors of low malignant potential) by surgery or biopsy are excluded Patients with medical conditions that in the opinion of the investigator render treatment on this protocol unsafe should be excluded

Sampling Method

Non-Probability Sample

Overall Study Officials:

First Name & Middle Initial & Last Name & Degree

Vivian E von Gruenigen

Organizational Affiliation

Gynecologic Oncology Group

Official's Role

Principal Investigator

Facility Information:

Facility Name

University of Alabama at Birmingham Cancer Center

City

Birmingham

State/Province

Alabama

ZIP/Postal Code

35233

Country

United States

Facility Name

Gynecologic Oncology Group of Arizona

City

Phoenix

State/Province

Arizona

ZIP/Postal Code

85012

Country

United States

Facility Name

Saint Joseph's Hospital and Medical Center

City

Phoenix

State/Province

Arizona

ZIP/Postal Code

85013

Country

United States

Facility Name

Mayo Clinic Hospital in Arizona

City

Phoenix

State/Province

Arizona

ZIP/Postal Code

85054

Country

United States

Facility Name

Mayo Clinic in Arizona

City

Scottsdale

State/Province

Arizona

ZIP/Postal Code

85259

Country

United States

Facility Name

University of Arizona Cancer Center-North Campus

City

Tucson

State/Province

Arizona

ZIP/Postal Code

85719

Country

United States

Facility Name

John Muir Medical Center-Concord Campus

City

Concord

State/Province

California

ZIP/Postal Code

94520

Country

United States

Facility Name

UC San Diego Moores Cancer Center

City

La Jolla

State/Province

California

ZIP/Postal Code

92093

Country

United States

Facility Name

Palo Alto Medical Foundation-Gynecologic Oncology

City

Mountain View

State/Province

California

ZIP/Postal Code

94040

Country

United States

Facility Name

Saint Joseph Hospital - Orange

City

Orange

State/Province

California

ZIP/Postal Code

92868

Country

United States

Facility Name

UC Irvine Health/Chao Family Comprehensive Cancer Center

City

Orange

State/Province

California

ZIP/Postal Code

92868

Country

United States

Facility Name

Stanford Cancer Institute Palo Alto

City

Palo Alto

State/Province

California

ZIP/Postal Code

94304

Country

United States

Facility Name

UCSF Medical Center-Mount Zion

City

San Francisco

State/Province

California

ZIP/Postal Code

94115

Country

United States

Facility Name

Olive View-University of California Los Angeles Medical Center

City

Sylmar

State/Province

California

ZIP/Postal Code

91342

Country

United States

Facility Name

Rocky Mountain Gynecologic Oncology PC

City

Englewood

State/Province

Colorado

ZIP/Postal Code

80110

Country

United States

Facility Name

Danbury Hospital

City

Danbury

State/Province

Connecticut

ZIP/Postal Code

06810

Country

United States

Facility Name

Hartford Hospital

City

Hartford

State/Province

Connecticut

ZIP/Postal Code

06102

Country

United States

Facility Name

Smilow Cancer Hospital Care Center at Saint Francis

City

Hartford

State/Province

Connecticut

ZIP/Postal Code

06105

Country

United States

Facility Name

Middlesex Hospital

City

Middletown

State/Province

Connecticut

ZIP/Postal Code

06457

Country

United States

Facility Name

The Hospital of Central Connecticut

City

New Britain

State/Province

Connecticut

ZIP/Postal Code

06050

Country

United States

Facility Name

Yale University

City

New Haven

State/Province

Connecticut

ZIP/Postal Code

06520

Country

United States

Facility Name

Stamford Hospital/Bennett Cancer Center

City

Stamford

State/Province

Connecticut

ZIP/Postal Code

06904

Country

United States

Facility Name

Beebe Medical Center

City

Lewes

State/Province

Delaware

ZIP/Postal Code

19958

Country

United States

Facility Name

Christiana Gynecologic Oncology LLC

City

Newark

State/Province

Delaware

ZIP/Postal Code

19713

Country

United States

Facility Name

Delaware Clinical and Laboratory Physicians PA

City

Newark

State/Province

Delaware

ZIP/Postal Code

19713

Country

United States

Facility Name

Helen F Graham Cancer Center

City

Newark

State/Province

Delaware

ZIP/Postal Code

19713

Country

United States

Facility Name

Medical Oncology Hematology Consultants PA

City

Newark

State/Province

Delaware

ZIP/Postal Code

19713

Country

United States

Facility Name

Christiana Care Health System-Christiana Hospital

City

Newark

State/Province

Delaware

ZIP/Postal Code

19718

Country

United States

Facility Name

Beebe Health Campus

City

Rehoboth Beach

State/Province

Delaware

ZIP/Postal Code

19971

Country

United States

Facility Name

Christiana Care Health System-Wilmington Hospital

City

Wilmington

State/Province

Delaware

ZIP/Postal Code

19801

Country

United States

Facility Name

Holy Cross Hospital

City

Fort Lauderdale

State/Province

Florida

ZIP/Postal Code

33308

Country

United States

Facility Name

Florida Gynecologic Oncology

City

Fort Myers

State/Province

Florida

ZIP/Postal Code

33905

Country

United States

Facility Name

Jupiter Medical Center

City

Jupiter

State/Province

Florida

ZIP/Postal Code

33458

Country

United States

Facility Name

Mount Sinai Medical Center

City

Miami Beach

State/Province

Florida

ZIP/Postal Code

33140

Country

United States

Facility Name

Mercy Hospital

City

Miami

State/Province

Florida

ZIP/Postal Code

33133

Country

United States

Facility Name

Sarasota Memorial Hospital

City

Sarasota

State/Province

Florida

ZIP/Postal Code

34239

Country

United States

Facility Name

Moffitt Cancer Center

City

Tampa

State/Province

Florida

ZIP/Postal Code

33612

Country

United States

Facility Name

Augusta University Medical Center

City

Augusta

State/Province

Georgia

ZIP/Postal Code

30912

Country

United States

Facility Name

John B Amos Cancer Center

City

Columbus

State/Province

Georgia

ZIP/Postal Code

31904

Country

United States

Facility Name

Dekalb Medical Center

City

Decatur

State/Province

Georgia

ZIP/Postal Code

30033

Country

United States

Facility Name

Northeast Georgia Medical Center-Gainesville

City

Gainesville

State/Province

Georgia

ZIP/Postal Code

30501

Country

United States

Facility Name

Memorial Health University Medical Center

City

Savannah

State/Province

Georgia

ZIP/Postal Code

31404

Country

United States

Facility Name

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

City

Savannah

State/Province

Georgia

ZIP/Postal Code

31405

Country

United States

Facility Name

Saint Alphonsus Cancer Care Center-Boise

City

Boise

State/Province

Idaho

ZIP/Postal Code

83706

Country

United States

Facility Name

Northwestern University

City

Chicago

State/Province

Illinois

ZIP/Postal Code

60611

Country

United States

Facility Name

University of Chicago Comprehensive Cancer Center

City

Chicago

State/Province

Illinois

ZIP/Postal Code

60637

Country

United States

Facility Name

Weiss Memorial Hospital

City

Chicago

State/Province

Illinois

ZIP/Postal Code

60640

Country

United States

Facility Name

Sudarshan K Sharma MD Limited-Gynecologic Oncology

City

Hinsdale

State/Province

Illinois

ZIP/Postal Code

60521

Country

United States

Facility Name

Good Samaritan Regional Health Center

City

Mount Vernon

State/Province

Illinois

ZIP/Postal Code

62864

Country

United States

Facility Name

West Suburban Medical Center

City

River Forest

State/Province

Illinois

ZIP/Postal Code

60305

Country

United States

Facility Name

Northwestern Medicine Cancer Center Warrenville

City

Warrenville

State/Province

Illinois

ZIP/Postal Code

60555

Country

United States

Facility Name

Franciscan Saint Francis Health-Beech Grove

City

Beech Grove

State/Province

Indiana

ZIP/Postal Code

46107

Country

United States

Facility Name

Elkhart Clinic

City

Elkhart

State/Province

Indiana

ZIP/Postal Code

46514-2098

Country

United States

Facility Name

Michiana Hematology Oncology PC-Elkhart

City

Elkhart

State/Province

Indiana

ZIP/Postal Code

46514

Country

United States

Facility Name

Elkhart General Hospital

City

Elkhart

State/Province

Indiana

ZIP/Postal Code

46515

Country

United States

Facility Name

Franciscan Health Indianapolis

City

Indianapolis

State/Province

Indiana

ZIP/Postal Code

46237

Country

United States

Facility Name

Saint Vincent Hospital and Health Care Center

City

Indianapolis

State/Province

Indiana

ZIP/Postal Code

46260

Country

United States

Facility Name

Community Howard Regional Health

City

Kokomo

State/Province

Indiana

ZIP/Postal Code

46904

Country

United States

Facility Name

IU Health La Porte Hospital

City

La Porte

State/Province

Indiana

ZIP/Postal Code

46350

Country

United States

Facility Name

Cancer Care Partners LLC

City

Mishawaka

State/Province

Indiana

ZIP/Postal Code

46545

Country

United States

Facility Name

Michiana Hematology Oncology PC-Mishawaka

City

Mishawaka

State/Province

Indiana

ZIP/Postal Code

46545

Country

United States

Facility Name

Saint Joseph Regional Medical Center-Mishawaka

City

Mishawaka

State/Province

Indiana

ZIP/Postal Code

46545

Country

United States

Facility Name

Michiana Hematology Oncology PC-Plymouth

City

Plymouth

State/Province

Indiana

ZIP/Postal Code

46563

Country

United States

Facility Name

Reid Health

City

Richmond

State/Province

Indiana

ZIP/Postal Code

47374

Country

United States

Facility Name

Memorial Hospital of South Bend

City

South Bend

State/Province

Indiana

ZIP/Postal Code

46601

Country

United States

Facility Name

Michiana Hematology Oncology PC-South Bend

City

South Bend

State/Province

Indiana

ZIP/Postal Code

46601

Country

United States

Facility Name

South Bend Clinic

City

South Bend

State/Province

Indiana

ZIP/Postal Code

46617

Country

United States

Facility Name

Northern Indiana Cancer Research Consortium

City

South Bend

State/Province

Indiana

ZIP/Postal Code

46628

Country

United States

Facility Name

Michiana Hematology Oncology PC-Westville

City

Westville

State/Province

Indiana

ZIP/Postal Code

46391

Country

United States

Facility Name

Mary Greeley Medical Center

City

Ames

State/Province

Iowa

ZIP/Postal Code

50010

Country

United States

Facility Name

McFarland Clinic PC - Ames

City

Ames

State/Province

Iowa

ZIP/Postal Code

50010

Country

United States

Facility Name

McFarland Clinic PC-Boone

City

Boone

State/Province

Iowa

ZIP/Postal Code

50036

Country

United States

Facility Name

Mercy Hospital

City

Cedar Rapids

State/Province

Iowa

ZIP/Postal Code

52403

Country

United States

Facility Name

Oncology Associates at Mercy Medical Center

City

Cedar Rapids

State/Province

Iowa

ZIP/Postal Code

52403

Country

United States

Facility Name

Medical Oncology and Hematology Associates-West Des Moines

City

Clive

State/Province

Iowa

ZIP/Postal Code

50325

Country

United States

Facility Name

Mercy Cancer Center-West Lakes

City

Clive

State/Province

Iowa

ZIP/Postal Code

50325

Country

United States

Facility Name

Iowa Methodist Medical Center

City

Des Moines

State/Province

Iowa

ZIP/Postal Code

50309

Country

United States

Facility Name

Iowa-Wide Oncology Research Coalition NCORP

City

Des Moines

State/Province

Iowa

ZIP/Postal Code

50309

Country

United States

Facility Name

Medical Oncology and Hematology Associates-Des Moines

City

Des Moines

State/Province

Iowa

ZIP/Postal Code

50309

Country

United States

Facility Name

Medical Oncology and Hematology Associates-Laurel

City

Des Moines

State/Province

Iowa

ZIP/Postal Code

50314

Country

United States

Facility Name

Mercy Medical Center - Des Moines

City

Des Moines

State/Province

Iowa

ZIP/Postal Code

50314

Country

United States

Facility Name

Iowa Lutheran Hospital

City

Des Moines

State/Province

Iowa

ZIP/Postal Code

50316

Country

United States

Facility Name

University of Iowa/Holden Comprehensive Cancer Center

City

Iowa City

State/Province

Iowa

ZIP/Postal Code

52242

Country

United States

Facility Name

McFarland Clinic PC-Jefferson

City

Jefferson

State/Province

Iowa

ZIP/Postal Code

50129

Country

United States

Facility Name

McFarland Clinic PC-Marshalltown

City

Marshalltown

State/Province

Iowa

ZIP/Postal Code

50158

Country

United States

Facility Name

Siouxland Regional Cancer Center

City

Sioux City

State/Province

Iowa

ZIP/Postal Code

51101

Country

United States

Facility Name

Mercy Medical Center-Sioux City

City

Sioux City

State/Province

Iowa

ZIP/Postal Code

51102

Country

United States

Facility Name

Saint Luke's Regional Medical Center

City

Sioux City

State/Province

Iowa

ZIP/Postal Code

51104

Country

United States

Facility Name

Methodist West Hospital

City

West Des Moines

State/Province

Iowa

ZIP/Postal Code

50266-7700

Country

United States

Facility Name

Mercy Medical Center-West Lakes

City

West Des Moines

State/Province

Iowa

ZIP/Postal Code

50266

Country

United States

Facility Name

Cancer Center of Kansas - Chanute

City

Chanute

State/Province

Kansas

ZIP/Postal Code

66720

Country

United States

Facility Name

Cancer Center of Kansas - Dodge City

City

Dodge City

State/Province

Kansas

ZIP/Postal Code

67801

Country

United States

Facility Name

Cancer Center of Kansas - El Dorado

City

El Dorado

State/Province

Kansas

ZIP/Postal Code

67042

Country

United States

Facility Name

Cancer Center of Kansas - Fort Scott

City

Fort Scott

State/Province

Kansas

ZIP/Postal Code

66701

Country

United States

Facility Name

Cancer Center of Kansas-Independence

City

Independence

State/Province

Kansas

ZIP/Postal Code

67301

Country

United States

Facility Name

Providence Medical Center

City

Kansas City

State/Province

Kansas

ZIP/Postal Code

66112

Country

United States

Facility Name

Cancer Center of Kansas-Kingman

City

Kingman

State/Province

Kansas

ZIP/Postal Code

67068

Country

United States

Facility Name

Lawrence Memorial Hospital

City

Lawrence

State/Province

Kansas

ZIP/Postal Code

66044

Country

United States

Facility Name

Cancer Center of Kansas-Liberal

City

Liberal

State/Province

Kansas

ZIP/Postal Code

67905

Country

United States

Facility Name

Cancer Center of Kansas-Manhattan

City

Manhattan

State/Province

Kansas

ZIP/Postal Code

66502

Country

United States

Facility Name

Cancer Center of Kansas - McPherson

City

McPherson

State/Province

Kansas

ZIP/Postal Code

67460

Country

United States

Facility Name

Cancer Center of Kansas - Newton

City

Newton

State/Province

Kansas

ZIP/Postal Code

67114

Country

United States

Facility Name

Menorah Medical Center

City

Overland Park

State/Province

Kansas

ZIP/Postal Code

66209

Country

United States

Facility Name

Saint Luke's South Hospital

City

Overland Park

State/Province

Kansas

ZIP/Postal Code

66213

Country

United States

Facility Name

Cancer Center of Kansas - Parsons

City

Parsons

State/Province

Kansas

ZIP/Postal Code

67357

Country

United States

Facility Name

Kansas City NCI Community Oncology Research Program

City

Prairie Village

State/Province

Kansas

ZIP/Postal Code

66208

Country

United States

Facility Name

Cancer Center of Kansas - Pratt

City

Pratt

State/Province

Kansas

ZIP/Postal Code

67124

Country

United States

Facility Name

Cancer Center of Kansas - Salina

City

Salina

State/Province

Kansas

ZIP/Postal Code

67401

Country

United States

Facility Name

Cotton O'Neil Cancer Center / Stormont Vail Health

City

Topeka

State/Province

Kansas

ZIP/Postal Code

66606

Country

United States

Facility Name

Cancer Center of Kansas - Wellington

City

Wellington

State/Province

Kansas

ZIP/Postal Code

67152

Country

United States

Facility Name

Associates In Womens Health

City

Wichita

State/Province

Kansas

ZIP/Postal Code

67208

Country

United States

Facility Name

Cancer Center of Kansas-Wichita Medical Arts Tower

City

Wichita

State/Province

Kansas

ZIP/Postal Code

67208

Country

United States

Facility Name

Ascension Via Christi Hospitals Wichita

City

Wichita

State/Province

Kansas

ZIP/Postal Code

67214

Country

United States

Facility Name

Cancer Center of Kansas - Wichita

City

Wichita

State/Province

Kansas

ZIP/Postal Code

67214

Country

United States

Facility Name

Wichita NCI Community Oncology Research Program

City

Wichita

State/Province

Kansas

ZIP/Postal Code

67214

Country

United States

Facility Name

Cancer Center of Kansas - Winfield

City

Winfield

State/Province

Kansas

ZIP/Postal Code

67156

Country

United States

Facility Name

Oncology Hematology Care Inc-Crestview

City

Crestview Hills

State/Province

Kentucky

ZIP/Postal Code

41017

Country

United States

Facility Name

Saint Elizabeth Medical Center South

City

Edgewood

State/Province

Kentucky

ZIP/Postal Code

41017

Country

United States

Facility Name

Baptist Health Lexington

City

Lexington

State/Province

Kentucky

ZIP/Postal Code

40503

Country

United States

Facility Name

Norton Hospital Pavilion and Medical Campus

City

Louisville

State/Province

Kentucky

ZIP/Postal Code

40202

Country

United States

Facility Name

Woman's Hospital

City

Baton Rouge

State/Province

Louisiana

ZIP/Postal Code

70817

Country

United States

Facility Name

Tulane University Health Sciences Center

City

New Orleans

State/Province

Louisiana

ZIP/Postal Code

70112

Country

United States

Facility Name

Ochsner Medical Center Jefferson

City

New Orleans

State/Province

Louisiana

ZIP/Postal Code

70121

Country

United States

Facility Name

Harold Alfond Center for Cancer Care

City

Augusta

State/Province

Maine

ZIP/Postal Code

04330

Country

United States

Facility Name

Eastern Maine Medical Center

City

Bangor

State/Province

Maine

ZIP/Postal Code

04401

Country

United States

Facility Name

Maine Medical Center-Bramhall Campus

City

Portland

State/Province

Maine

ZIP/Postal Code

04102

Country

United States

Facility Name

University of Maryland/Greenebaum Cancer Center

City

Baltimore

State/Province

Maryland

ZIP/Postal Code

21201

Country

United States

Facility Name

Greater Baltimore Medical Center

City

Baltimore

State/Province

Maryland

ZIP/Postal Code

21204

Country

United States

Facility Name

Christiana Care - Union Hospital

City

Elkton

State/Province

Maryland

ZIP/Postal Code

21921

Country

United States

Facility Name

Boston Medical Center

City

Boston

State/Province

Massachusetts

ZIP/Postal Code

02118

Country

United States

Facility Name

Lahey Hospital and Medical Center

City

Burlington

State/Province

Massachusetts

ZIP/Postal Code

01805

Country

United States

Facility Name

Beth Israel Deaconess Hospital-Plymouth

City

Plymouth

State/Province

Massachusetts

ZIP/Postal Code

02360

Country

United States

Facility Name

UMass Memorial Medical Center - Memorial Division

City

Worcester

State/Province

Massachusetts

ZIP/Postal Code

01605

Country

United States

Facility Name

Michigan Cancer Research Consortium NCORP

City

Ann Arbor

State/Province

Michigan

ZIP/Postal Code

48106

Country

United States

Facility Name

Saint Joseph Mercy Hospital

City

Ann Arbor

State/Province

Michigan

ZIP/Postal Code

48106

Country

United States

Facility Name

Beaumont Hospital - Dearborn

City

Dearborn

State/Province

Michigan

ZIP/Postal Code

48124

Country

United States

Facility Name

Wayne State University/Karmanos Cancer Institute

City

Detroit

State/Province

Michigan

ZIP/Postal Code

48201

Country

United States

Facility Name

Henry Ford Hospital

City

Detroit

State/Province

Michigan

ZIP/Postal Code

48202

Country

United States

Facility Name

Ascension Saint John Hospital

City

Detroit

State/Province

Michigan

ZIP/Postal Code

48236

Country

United States

Facility Name

Green Bay Oncology - Escanaba

City

Escanaba

State/Province

Michigan

ZIP/Postal Code

49829

Country

United States

Facility Name

Genesys Hurley Cancer Institute

City

Flint

State/Province

Michigan

ZIP/Postal Code

48503

Country

United States

Facility Name

Hurley Medical Center

City

Flint

State/Province

Michigan

ZIP/Postal Code

48503

Country

United States

Facility Name

Genesys Regional Medical Center-West Flint Campus

City

Flint

State/Province

Michigan

ZIP/Postal Code

48532

Country

United States

Facility Name

Genesys Regional Medical Center

City

Grand Blanc

State/Province

Michigan

ZIP/Postal Code

48439

Country

United States

Facility Name

Green Bay Oncology - Iron Mountain

City

Iron Mountain

State/Province

Michigan

ZIP/Postal Code

49801

Country

United States

Facility Name

Allegiance Health

City

Jackson

State/Province

Michigan

ZIP/Postal Code

49201

Country

United States

Facility Name

Bronson Methodist Hospital

City

Kalamazoo

State/Province

Michigan

ZIP/Postal Code

49007

Country

United States

Facility Name

West Michigan Cancer Center

City

Kalamazoo

State/Province

Michigan

ZIP/Postal Code

49007

Country

United States

Facility Name

Borgess Medical Center

City

Kalamazoo

State/Province

Michigan

ZIP/Postal Code

49048

Country

United States

Facility Name

Sparrow Hospital

City

Lansing

State/Province

Michigan

ZIP/Postal Code

48912

Country

United States

Facility Name

Saint Mary Mercy Hospital

City

Livonia

State/Province

Michigan

ZIP/Postal Code

48154

Country

United States

Facility Name

Saint Joseph Mercy Oakland

City

Pontiac

State/Province

Michigan

ZIP/Postal Code

48341

Country

United States

Facility Name

Lake Huron Medical Center

City

Port Huron

State/Province

Michigan

ZIP/Postal Code

48060

Country

United States

Facility Name

William Beaumont Hospital-Royal Oak

City

Royal Oak

State/Province

Michigan

ZIP/Postal Code

48073

Country

United States

Facility Name

Ascension Saint Mary's Hospital

City

Saginaw

State/Province

Michigan

ZIP/Postal Code

48601

Country

United States

Facility Name

Lakeland Medical Center Saint Joseph

City

Saint Joseph

State/Province

Michigan

ZIP/Postal Code

49085

Country

United States

Facility Name

Marie Yeager Cancer Center

City

Saint Joseph

State/Province

Michigan

ZIP/Postal Code

49085

Country

United States

Facility Name

Ascension Providence Hospitals - Southfield

City

Southfield

State/Province

Michigan

ZIP/Postal Code

48075

Country

United States

Facility Name

William Beaumont Hospital - Troy

City

Troy

State/Province

Michigan

ZIP/Postal Code

48085

Country

United States

Facility Name

Saint John Macomb-Oakland Hospital

City

Warren

State/Province

Michigan

ZIP/Postal Code

48093

Country

United States

Facility Name

Sanford Joe Lueken Cancer Center

City

Bemidji

State/Province

Minnesota

ZIP/Postal Code

56601

Country

United States

Facility Name

Fairview Ridges Hospital

City

Burnsville

State/Province

Minnesota

ZIP/Postal Code

55337

Country

United States

Facility Name

Mercy Hospital

City

Coon Rapids

State/Province

Minnesota

ZIP/Postal Code

55433

Country

United States

Facility Name

Fairview Southdale Hospital

City

Edina

State/Province

Minnesota

ZIP/Postal Code

55435

Country

United States

Facility Name

Unity Hospital

City

Fridley

State/Province

Minnesota

ZIP/Postal Code

55432

Country

United States

Facility Name

Hutchinson Area Health Care

City

Hutchinson

State/Province

Minnesota

ZIP/Postal Code

55350

Country

United States

Facility Name

Minnesota Oncology Hematology PA-Maplewood

City

Maplewood

State/Province

Minnesota

ZIP/Postal Code

55109

Country

United States

Facility Name

Saint John's Hospital - Healtheast

City

Maplewood

State/Province

Minnesota

ZIP/Postal Code

55109

Country

United States

Facility Name

Abbott-Northwestern Hospital

City

Minneapolis

State/Province

Minnesota

ZIP/Postal Code

55407

Country

United States

Facility Name

Hennepin County Medical Center

City

Minneapolis

State/Province

Minnesota

ZIP/Postal Code

55415

Country

United States

Facility Name

University of Minnesota/Masonic Cancer Center

City

Minneapolis

State/Province

Minnesota

ZIP/Postal Code

55455

Country

United States

Facility Name

New Ulm Medical Center

City

New Ulm

State/Province

Minnesota

ZIP/Postal Code

56073

Country

United States

Facility Name

North Memorial Medical Health Center

City

Robbinsdale

State/Province

Minnesota

ZIP/Postal Code

55422

Country

United States

Facility Name

Mayo Clinic in Rochester

City

Rochester

State/Province

Minnesota

ZIP/Postal Code

55905

Country

United States

Facility Name

Metro Minnesota Community Oncology Research Consortium

City

Saint Louis Park

State/Province

Minnesota

ZIP/Postal Code

55416

Country

United States

Facility Name

Park Nicollet Clinic - Saint Louis Park

City

Saint Louis Park

State/Province

Minnesota

ZIP/Postal Code

55416

Country

United States

Facility Name

Park Nicollet Frauenshuh Cancer Center

City

Saint Louis Park

State/Province

Minnesota

ZIP/Postal Code

55426

Country

United States

Facility Name

Regions Hospital

City

Saint Paul

State/Province

Minnesota

ZIP/Postal Code

55101

Country

United States

Facility Name

United Hospital

City

Saint Paul

State/Province

Minnesota

ZIP/Postal Code

55102

Country

United States

Facility Name

Saint Francis Regional Medical Center

City

Shakopee

State/Province

Minnesota

ZIP/Postal Code

55379

Country

United States

Facility Name

Lakeview Hospital

City

Stillwater

State/Province

Minnesota

ZIP/Postal Code

55082

Country

United States

Facility Name

Ridgeview Medical Center

City

Waconia

State/Province

Minnesota

ZIP/Postal Code

55387

Country

United States

Facility Name

Rice Memorial Hospital

City

Willmar

State/Province

Minnesota

ZIP/Postal Code

56201

Country

United States

Facility Name

Minnesota Oncology Hematology PA-Woodbury

City

Woodbury

State/Province

Minnesota

ZIP/Postal Code

55125

Country

United States

Facility Name

Saint Luke's Hospital of Kansas City

City

Kansas City

State/Province

Missouri

ZIP/Postal Code

64111

Country

United States

Facility Name

North Kansas City Hospital

City

Kansas City

State/Province

Missouri

ZIP/Postal Code

64116

Country

United States

Facility Name

Heartland Hematology and Oncology Associates Incorporated

City

Kansas City

State/Province

Missouri

ZIP/Postal Code

64118

Country

United States

Facility Name

Research Medical Center

City

Kansas City

State/Province

Missouri

ZIP/Postal Code

64132

Country

United States

Facility Name

Saint Luke's East - Lee's Summit

City

Lee's Summit

State/Province

Missouri

ZIP/Postal Code

64086

Country

United States

Facility Name

Liberty Radiation Oncology Center

City

Liberty

State/Province

Missouri

ZIP/Postal Code

64068

Country

United States

Facility Name

Mercy Clinic-Rolla-Cancer and Hematology

City

Rolla

State/Province

Missouri

ZIP/Postal Code

65401

Country

United States

Facility Name

Heartland Regional Medical Center

City

Saint Joseph

State/Province

Missouri

ZIP/Postal Code

64506

Country

United States

Facility Name

Saint Joseph Oncology Inc

City

Saint Joseph

State/Province

Missouri

ZIP/Postal Code

64507

Country

United States

Facility Name

Washington University School of Medicine

City

Saint Louis

State/Province

Missouri

ZIP/Postal Code

63110

Country

United States

Facility Name

Cancer Research for the Ozarks NCORP

City

Springfield

State/Province

Missouri

ZIP/Postal Code

65804

Country

United States

Facility Name

Mercy Hospital Springfield

City

Springfield

State/Province

Missouri

ZIP/Postal Code

65804

Country

United States

Facility Name

CoxHealth South Hospital

City

Springfield

State/Province

Missouri

ZIP/Postal Code

65807

Country

United States

Facility Name

Billings Clinic Cancer Center

City

Billings

State/Province

Montana

ZIP/Postal Code

59101

Country

United States

Facility Name

Saint Vincent Healthcare

City

Billings

State/Province

Montana

ZIP/Postal Code

59101

Country

United States

Facility Name

Montana Cancer Consortium NCORP

City

Billings

State/Province

Montana

ZIP/Postal Code

59102

Country

United States

Facility Name

Saint Vincent Frontier Cancer Center

City

Billings

State/Province

Montana

ZIP/Postal Code

59102

Country

United States

Facility Name

Bozeman Deaconess Hospital

City

Bozeman

State/Province

Montana

ZIP/Postal Code

59715

Country

United States

Facility Name

Saint James Community Hospital and Cancer Treatment Center

City

Butte

State/Province

Montana

ZIP/Postal Code

59701

Country

United States

Facility Name

Benefis Healthcare- Sletten Cancer Institute

City

Great Falls

State/Province

Montana

ZIP/Postal Code

59405

Country

United States

Facility Name

Great Falls Clinic

City

Great Falls

State/Province

Montana

ZIP/Postal Code

59405

Country

United States

Facility Name

Northern Montana Hospital

City

Havre

State/Province

Montana

ZIP/Postal Code

59501

Country

United States

Facility Name

Saint Peter's Community Hospital

City

Helena

State/Province

Montana

ZIP/Postal Code

59601

Country

United States

Facility Name

Glacier Oncology PLLC

City

Kalispell

State/Province

Montana

ZIP/Postal Code

59901

Country

United States

Facility Name

Kalispell Medical Oncology

City

Kalispell

State/Province

Montana

ZIP/Postal Code

59901

Country

United States

Facility Name

Kalispell Regional Medical Center

City

Kalispell

State/Province

Montana

ZIP/Postal Code

59901

Country

United States

Facility Name

Montana Cancer Specialists

City

Missoula

State/Province

Montana

ZIP/Postal Code

59802

Country

United States

Facility Name

Saint Patrick Hospital - Community Hospital

City

Missoula

State/Province

Montana

ZIP/Postal Code

59802

Country

United States

Facility Name

CHI Health Good Samaritan

City

Kearney

State/Province

Nebraska

ZIP/Postal Code

68847

Country

United States

Facility Name

Nebraska Methodist Hospital

City

Omaha

State/Province

Nebraska

ZIP/Postal Code

68114

Country

United States

Facility Name

Women's Cancer Center of Nevada

City

Las Vegas

State/Province

Nevada

ZIP/Postal Code

89169

Country

United States

Facility Name

Cooper Hospital University Medical Center

City

Camden

State/Province

New Jersey

ZIP/Postal Code

08103

Country

United States

Facility Name

Hackensack University Medical Center

City

Hackensack

State/Province

New Jersey

ZIP/Postal Code

07601

Country

United States

Facility Name

Virtua Memorial

City

Mount Holly

State/Province

New Jersey

ZIP/Postal Code

08060

Country

United States

Facility Name

Rutgers New Jersey Medical School

City

Newark

State/Province

New Jersey

ZIP/Postal Code

07101

Country

United States

Facility Name

Virtua Voorhees

City

Voorhees

State/Province

New Jersey

ZIP/Postal Code

08043

Country

United States

Facility Name

University of New Mexico Cancer Center

City

Albuquerque

State/Province

New Mexico

ZIP/Postal Code

87102

Country

United States

Facility Name

Southwest Gynecologic Oncology Associates Inc

City

Albuquerque

State/Province

New Mexico

ZIP/Postal Code

87106

Country

United States

Facility Name

Women's Cancer Care Associates LLC

City

Albany

State/Province

New York

ZIP/Postal Code

12208

Country

United States

Facility Name

State University of New York Downstate Medical Center

City

Brooklyn

State/Province

New York

ZIP/Postal Code

11203

Country

United States

Facility Name

Roswell Park Cancer Institute

City

Buffalo

State/Province

New York

ZIP/Postal Code

14263

Country

United States

Facility Name

Glens Falls Hospital

City

Glens Falls

State/Province

New York

ZIP/Postal Code

12801

Country

United States

Facility Name

Northwell Health/Center for Advanced Medicine

City

Lake Success

State/Province

New York

ZIP/Postal Code

11042

Country

United States

Facility Name

North Shore University Hospital

City

Manhasset

State/Province

New York

ZIP/Postal Code

11030

Country

United States

Facility Name

Long Island Jewish Medical Center

City

New Hyde Park

State/Province

New York

ZIP/Postal Code

11040

Country

United States

Facility Name

Laura and Isaac Perlmutter Cancer Center at NYU Langone

City

New York

State/Province

New York

ZIP/Postal Code

10016

Country

United States

Facility Name

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center

City

New York

State/Province

New York

ZIP/Postal Code

10032

Country

United States

Facility Name

Memorial Sloan Kettering Cancer Center

City

New York

State/Province

New York

ZIP/Postal Code

10065

Country

United States

Facility Name

Stony Brook University Medical Center

City

Stony Brook

State/Province

New York

ZIP/Postal Code

11794

Country

United States

Facility Name

State University of New York Upstate Medical University

City

Syracuse

State/Province

New York

ZIP/Postal Code

13210

Country

United States

Facility Name

Cone Health Cancer Center at Alamance Regional

City

Burlington

State/Province

North Carolina

ZIP/Postal Code

27215

Country

United States

Facility Name

UNC Lineberger Comprehensive Cancer Center

City

Chapel Hill

State/Province

North Carolina

ZIP/Postal Code

27599

Country

United States

Facility Name

Carolinas Medical Center/Levine Cancer Institute

City

Charlotte

State/Province

North Carolina

ZIP/Postal Code

28203

Country

United States

Facility Name

Novant Health Presbyterian Medical Center

City

Charlotte

State/Province

North Carolina

ZIP/Postal Code

28204

Country

United States

Facility Name

Atrium Health Cabarrus/LCI-Concord

City

Concord

State/Province

North Carolina

ZIP/Postal Code

28025

Country

United States

Facility Name

Duke University Medical Center

City

Durham

State/Province

North Carolina

ZIP/Postal Code

27710

Country

United States

Facility Name

Wayne Memorial Hospital

City

Goldsboro

State/Province

North Carolina

ZIP/Postal Code

27534

Country

United States

Facility Name

Duke Raleigh Hospital

City

Raleigh

State/Province

North Carolina

ZIP/Postal Code

27609

Country

United States

Facility Name

Wake Forest University Health Sciences

City

Winston-Salem

State/Province

North Carolina

ZIP/Postal Code

27157

Country

United States

Facility Name

Mid Dakota Clinic

City

Bismarck

State/Province

North Dakota

ZIP/Postal Code

58501

Country

United States

Facility Name

Saint Alexius Medical Center

City

Bismarck

State/Province

North Dakota

ZIP/Postal Code

58501

Country

United States

Facility Name

Sanford Bismarck Medical Center

City

Bismarck

State/Province

North Dakota

ZIP/Postal Code

58501

Country

United States

Facility Name

Sanford Broadway Medical Center

City

Fargo

State/Province

North Dakota

ZIP/Postal Code

58122

Country

United States

Facility Name

Sanford Clinic North-Fargo

City

Fargo

State/Province

North Dakota

ZIP/Postal Code

58122

Country

United States

Facility Name

Sanford Roger Maris Cancer Center

City

Fargo

State/Province

North Dakota

ZIP/Postal Code

58122

Country

United States

Facility Name

Summa Health System - Akron Campus

City

Akron

State/Province

Ohio

ZIP/Postal Code

44304

Country

United States

Facility Name

Cleveland Clinic Akron General

City

Akron

State/Province

Ohio

ZIP/Postal Code

44307

Country

United States

Facility Name

Strecker Cancer Center-Belpre

City

Belpre

State/Province

Ohio

ZIP/Postal Code

45714

Country

United States

Facility Name

Aultman Health Foundation

City

Canton

State/Province

Ohio

ZIP/Postal Code

44710

Country

United States

Facility Name

Adena Regional Medical Center

City

Chillicothe

State/Province

Ohio

ZIP/Postal Code

45601

Country

United States

Facility Name

Oncology Hematology Care Inc-Eden Park

City

Cincinnati

State/Province

Ohio

ZIP/Postal Code

45202

Country

United States

Facility Name

Oncology Hematology Care Inc-Mercy West

City

Cincinnati

State/Province

Ohio

ZIP/Postal Code

45211

Country

United States

Facility Name

Good Samaritan Hospital - Cincinnati

City

Cincinnati

State/Province

Ohio

ZIP/Postal Code

45220

Country

United States

Facility Name

Oncology Hematology Care Inc-Anderson

City

Cincinnati

State/Province

Ohio

ZIP/Postal Code

45230

Country

United States

Facility Name

Oncology Hematology Care Inc-Kenwood

City

Cincinnati

State/Province

Ohio

ZIP/Postal Code

45236

Country

United States

Facility Name

Bethesda North Hospital

City

Cincinnati

State/Province

Ohio

ZIP/Postal Code

45242

Country

United States

Facility Name

Oncology Hematology Care Inc-Blue Ash

City

Cincinnati

State/Province

Ohio

ZIP/Postal Code

45242

Country

United States

Facility Name

Case Western Reserve University

City

Cleveland

State/Province

Ohio

ZIP/Postal Code

44106

Country

United States

Facility Name

MetroHealth Medical Center

City

Cleveland

State/Province

Ohio

ZIP/Postal Code

44109

Country

United States

Facility Name

Cleveland Clinic Cancer Center/Fairview Hospital

City

Cleveland

State/Province

Ohio

ZIP/Postal Code

44111

Country

United States

Facility Name

Cleveland Clinic Foundation

City

Cleveland

State/Province

Ohio

ZIP/Postal Code

44195

Country

United States

Facility Name

Ohio State University Comprehensive Cancer Center

City

Columbus

State/Province

Ohio

ZIP/Postal Code

43210

Country

United States

Facility Name

Mount Carmel East Hospital

City

Columbus

State/Province

Ohio

ZIP/Postal Code

43213

Country

United States

Facility Name

Columbus Oncology and Hematology Associates Inc

City

Columbus

State/Province

Ohio

ZIP/Postal Code

43214

Country

United States

Facility Name

Riverside Methodist Hospital

City

Columbus

State/Province

Ohio

ZIP/Postal Code

43214

Country

United States

Facility Name

Columbus NCI Community Oncology Research Program

City

Columbus

State/Province

Ohio

ZIP/Postal Code

43215

Country

United States

Facility Name

Grant Medical Center

City

Columbus

State/Province

Ohio

ZIP/Postal Code

43215

Country

United States

Facility Name

The Mark H Zangmeister Center

City

Columbus

State/Province

Ohio

ZIP/Postal Code

43219

Country

United States

Facility Name

Mount Carmel Health Center West

City

Columbus

State/Province

Ohio

ZIP/Postal Code

43222

Country

United States

Facility Name

Doctors Hospital

City

Columbus

State/Province

Ohio

ZIP/Postal Code

43228

Country

United States

Facility Name

Grandview Hospital

City

Dayton

State/Province

Ohio

ZIP/Postal Code

45405

Country

United States

Facility Name

Good Samaritan Hospital - Dayton

City

Dayton

State/Province

Ohio

ZIP/Postal Code

45406

Country

United States

Facility Name

Miami Valley Hospital

City

Dayton

State/Province

Ohio

ZIP/Postal Code

45409

Country

United States

Facility Name

Miami Valley Hospital North

City

Dayton

State/Province

Ohio

ZIP/Postal Code

45415

Country

United States

Facility Name

Dayton NCI Community Oncology Research Program

City

Dayton

State/Province

Ohio

ZIP/Postal Code

45459

Country

United States

Facility Name

Delaware Health Center-Grady Cancer Center

City

Delaware

State/Province

Ohio

ZIP/Postal Code

43015

Country

United States

Facility Name

Delaware Radiation Oncology

City

Delaware

State/Province

Ohio

ZIP/Postal Code

43015

Country

United States

Facility Name

Grady Memorial Hospital

City

Delaware

State/Province

Ohio

ZIP/Postal Code

43015

Country

United States

Facility Name

Oncology Hematology Care Inc-Healthplex

City

Fairfield

State/Province

Ohio

ZIP/Postal Code

45014

Country

United States

Facility Name

Blanchard Valley Hospital

City

Findlay

State/Province

Ohio

ZIP/Postal Code

45840

Country

United States

Facility Name

Atrium Medical Center-Middletown Regional Hospital

City

Franklin

State/Province

Ohio

ZIP/Postal Code

45005-1066

Country

United States

Facility Name

Wayne Hospital

City

Greenville

State/Province

Ohio

ZIP/Postal Code

45331

Country

United States

Facility Name

Fairfield Medical Center

City

Lancaster

State/Province

Ohio

ZIP/Postal Code

43130

Country

United States

Facility Name

Lancaster Radiation Oncology

City

Lancaster

State/Province

Ohio

ZIP/Postal Code

43130

Country

United States

Facility Name

Marietta Memorial Hospital

City

Marietta

State/Province

Ohio

ZIP/Postal Code

45750

Country

United States

Facility Name

Hillcrest Hospital Cancer Center

City

Mayfield Heights

State/Province

Ohio

ZIP/Postal Code

44124

Country

United States

Facility Name

UH Seidman Cancer Center at Lake Health Mentor Campus

City

Mentor

State/Province

Ohio

ZIP/Postal Code

44060

Country

United States

Facility Name

Knox Community Hospital

City

Mount Vernon

State/Province

Ohio

ZIP/Postal Code

43050

Country

United States

Facility Name

Licking Memorial Hospital

City

Newark

State/Province

Ohio

ZIP/Postal Code

43055

Country

United States

Facility Name

Newark Radiation Oncology

City

Newark

State/Province

Ohio

ZIP/Postal Code

43055

Country

United States

Facility Name

Southern Ohio Medical Center

City

Portsmouth

State/Province

Ohio

ZIP/Postal Code

45662

Country

United States

Facility Name

Springfield Regional Medical Center

City

Springfield

State/Province

Ohio

ZIP/Postal Code

45505

Country

United States

Facility Name

Upper Valley Medical Center

City

Troy

State/Province

Ohio

ZIP/Postal Code

45373

Country

United States

Facility Name

Saint Ann's Hospital

City

Westerville

State/Province

Ohio

ZIP/Postal Code

43081

Country

United States

Facility Name

Greene Memorial Hospital

City

Xenia

State/Province

Ohio

ZIP/Postal Code

45385

Country

United States

Facility Name

Genesis Healthcare System Cancer Care Center

City

Zanesville

State/Province

Ohio

ZIP/Postal Code

43701

Country

United States

Facility Name

University of Oklahoma Health Sciences Center

City

Oklahoma City

State/Province

Oklahoma

ZIP/Postal Code

73104

Country

United States

Facility Name

Natalie Warren Bryant Cancer Center at Saint Francis

City

Tulsa

State/Province

Oklahoma

ZIP/Postal Code

74136

Country

United States

Facility Name

Warren Clinic-Tulsa South

City

Tulsa

State/Province

Oklahoma

ZIP/Postal Code

74136

Country

United States

Facility Name

Oklahoma Cancer Specialists and Research Institute-Tulsa

City

Tulsa

State/Province

Oklahoma

ZIP/Postal Code

74146

Country

United States

Facility Name

Warren Clinic Oncology-Tulsa

City

Tulsa

State/Province

Oklahoma

ZIP/Postal Code

74146

Country

United States

Facility Name

Saint Luke's University Hospital-Bethlehem Campus

City

Bethlehem

State/Province

Pennsylvania

ZIP/Postal Code

18015

Country

United States

Facility Name

Adams Cancer Center

City

Gettysburg

State/Province

Pennsylvania

ZIP/Postal Code

17325

Country

United States

Facility Name

Cherry Tree Cancer Center

City

Hanover

State/Province

Pennsylvania

ZIP/Postal Code

17331

Country

United States

Facility Name

Thomas Jefferson University Hospital

City

Philadelphia

State/Province

Pennsylvania

ZIP/Postal Code

19107

Country

United States

Facility Name

Fox Chase Cancer Center

City

Philadelphia

State/Province

Pennsylvania

ZIP/Postal Code

19111

Country

United States

Facility Name

Temple University Hospital

City

Philadelphia

State/Province

Pennsylvania

ZIP/Postal Code

19140

Country

United States

Facility Name

University of Pittsburgh Cancer Institute (UPCI)

City

Pittsburgh

State/Province

Pennsylvania

ZIP/Postal Code

15232

Country

United States

Facility Name

Guthrie Medical Group PC-Robert Packer Hospital

City

Sayre

State/Province

Pennsylvania

ZIP/Postal Code

18840

Country

United States

Facility Name

Chester County Hospital

City

West Chester

State/Province

Pennsylvania

ZIP/Postal Code

19380

Country

United States

Facility Name

Reading Hospital

City

West Reading

State/Province

Pennsylvania

ZIP/Postal Code

19611

Country

United States

Facility Name

WellSpan Health-York Hospital

City

York

State/Province

Pennsylvania

ZIP/Postal Code

17403

Country

United States

Facility Name

Women and Infants Hospital

City

Providence

State/Province

Rhode Island

ZIP/Postal Code

02905

Country

United States

Facility Name

Sanford Cancer Center Oncology Clinic

City

Sioux Falls

State/Province

South Dakota

ZIP/Postal Code

57104

Country

United States

Facility Name

Avera Cancer Institute

City

Sioux Falls

State/Province

South Dakota

ZIP/Postal Code

57105

Country

United States

Facility Name

Sanford USD Medical Center - Sioux Falls

City

Sioux Falls

State/Province

South Dakota

ZIP/Postal Code

57117-5134

Country

United States

Facility Name

University of Tennessee - Knoxville

City

Knoxville

State/Province

Tennessee

ZIP/Postal Code

37920

Country

United States

Facility Name

M D Anderson Cancer Center

City

Houston

State/Province

Texas

ZIP/Postal Code

77030

Country

United States

Facility Name

Scott and White Memorial Hospital

City

Temple

State/Province

Texas

ZIP/Postal Code

76508

Country

United States

Facility Name

University of Vermont Medical Center

City

Burlington

State/Province

Vermont

ZIP/Postal Code

05401

Country

United States

Facility Name

Carilion Clinic Gynecological Oncology

City

Roanoke

State/Province

Virginia

ZIP/Postal Code

24016

Country

United States

Facility Name

Monongalia Hospital

City

Morgantown

State/Province

West Virginia

ZIP/Postal Code

26505

Country

United States

Facility Name

Marshfield Clinic Cancer Center at Sacred Heart

City

Eau Claire

State/Province

Wisconsin

ZIP/Postal Code

54701

Country

United States

Facility Name

Green Bay Oncology at Saint Vincent Hospital

City

Green Bay

State/Province

Wisconsin

ZIP/Postal Code

54301-3526

Country

United States

Facility Name

Saint Vincent Hospital Cancer Center Green Bay

City

Green Bay

State/Province

Wisconsin

ZIP/Postal Code

54301

Country

United States

Facility Name

Green Bay Oncology Limited at Saint Mary's Hospital

City

Green Bay

State/Province

Wisconsin

ZIP/Postal Code

54303

Country

United States

Facility Name

Saint Vincent Hospital Cancer Center at Saint Mary's

City

Green Bay

State/Province

Wisconsin

ZIP/Postal Code

54303

Country

United States

Facility Name

Gundersen Lutheran Medical Center

City

La Crosse

State/Province

Wisconsin

ZIP/Postal Code

54601

Country

United States

Facility Name

University of Wisconsin Hospital and Clinics

City

Madison

State/Province

Wisconsin

ZIP/Postal Code

53792

Country

United States

Facility Name

Holy Family Memorial Hospital

City

Manitowoc

State/Province

Wisconsin

ZIP/Postal Code

54221

Country

United States

Facility Name

Bay Area Medical Center

City

Marinette

State/Province

Wisconsin

ZIP/Postal Code

54143

Country

United States

Facility Name

Marshfield Medical Center-Marshfield

City

Marshfield

State/Province

Wisconsin

ZIP/Postal Code

54449

Country

United States

Facility Name

Aurora Saint Luke's Medical Center

City

Milwaukee

State/Province

Wisconsin

ZIP/Postal Code

53215

Country

United States

Facility Name

Medical College of Wisconsin

City

Milwaukee

State/Province

Wisconsin

ZIP/Postal Code

53226

Country

United States

Facility Name

Marshfield Clinic-Minocqua Center

City

Minocqua

State/Province

Wisconsin

ZIP/Postal Code

54548

Country

United States

Facility Name

ProHealth D N Greenwald Center

City

Mukwonago

State/Province

Wisconsin

ZIP/Postal Code

53149

Country

United States

Facility Name

Cancer Center of Western Wisconsin

City

New Richmond

State/Province

Wisconsin

ZIP/Postal Code

54017

Country

United States

Facility Name

ProHealth Oconomowoc Memorial Hospital

City

Oconomowoc

State/Province

Wisconsin

ZIP/Postal Code

53066

Country

United States

Facility Name

Saint Vincent Hospital Cancer Center at Oconto Falls

City

Oconto Falls

State/Province

Wisconsin

ZIP/Postal Code

54154

Country

United States

Facility Name

Vince Lombardi Cancer Clinic - Oshkosh

City

Oshkosh

State/Province

Wisconsin

ZIP/Postal Code

54904

Country

United States

Facility Name

Ascension Saint Mary's Hospital

City

Rhinelander

State/Province

Wisconsin

ZIP/Postal Code

54501

Country

United States

Facility Name

Marshfield Medical Center-Rice Lake

City

Rice Lake

State/Province

Wisconsin

ZIP/Postal Code

54868

Country

United States

Facility Name

Vince Lombardi Cancer Clinic-Sheboygan

City

Sheboygan

State/Province

Wisconsin

ZIP/Postal Code

53081

Country

United States

Facility Name

Ascension Saint Michael's Hospital

City

Stevens Point

State/Province

Wisconsin

ZIP/Postal Code

54481

Country

United States

Facility Name

Green Bay Oncology - Sturgeon Bay

City

Sturgeon Bay

State/Province

Wisconsin

ZIP/Postal Code

54235

Country

United States

Facility Name

Aurora Medical Center in Summit

City

Summit

State/Province

Wisconsin

ZIP/Postal Code

53066

Country

United States

Facility Name

ProHealth Waukesha Memorial Hospital

City

Waukesha

State/Province

Wisconsin

ZIP/Postal Code

53188

Country

United States

Facility Name

Marshfield Clinic-Wausau Center

City

Wausau

State/Province

Wisconsin

ZIP/Postal Code

54401

Country

United States

Facility Name

Aurora West Allis Medical Center

City

West Allis

State/Province

Wisconsin

ZIP/Postal Code

53227

Country

United States

Facility Name

Marshfield Medical Center - Weston

City

Weston

State/Province

Wisconsin

ZIP/Postal Code

54476

Country

United States

Facility Name

Marshfield Clinic - Wisconsin Rapids Center

City

Wisconsin Rapids

State/Province

Wisconsin

ZIP/Postal Code

54494

Country

United States

Facility Name

Rocky Mountain Oncology

City

Casper

State/Province

Wyoming

ZIP/Postal Code

82609

Country

United States

Facility Name

Welch Cancer Center

City

Sheridan

State/Province

Wyoming

ZIP/Postal Code

82801

Country

United States

12. IPD Sharing Statement

Learn more about this trial

Chemotherapy Toxicity On Quality of Life in Older Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer

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