Back to resultsEffect of Wide Pulse Pressure on the Predictability of Stroke Volume Variation for Fluid Responsiveness in Patients Undergoing Off-pump Coronary Artery Bypass Graft
Primary Purpose
Stroke Volume Variation
Status
Completed
Phase
Not Applicable
Locations
Korea, Republic of
Study Type
Interventional
Intervention
HES 130/0.4 (VoluvenⓇ, Fresenius Kabi, Graz, Austria) 500mL loading
Sponsored by
About this trial
This is an interventional screening trial for Stroke Volume Variation
Eligibility Criteria
Inclusion Criteria:
- 1. Age ≥ 20
- 2. elective off-pump coronary artery bypass graft
Exclusion Criteria:
- 1. arrhythmia
- 2.EF <40%
- 3.valvular heart dz
- 4.pul HTN
- 5.PAOD
- 6.lung dz
- 7.NYHA IV
- 8.ESRD
Sites / Locations
- Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine
Arms of the Study
Arm 1
Arm 2
Arm Type
Other
Other
Arm Label
Normal pulse pressure
Wide pulse pressure
Arm Description
pulse pressure <60mmHg
pulse pressure ≥60mmHg
Outcomes
Primary Outcome Measures
The predictability of stroke volume variation for fluid responsiveness in patients with wide pulse pressure
Secondary Outcome Measures
Cut off value of stroke volume variation for predicting fluid responsiveness in patients with wide pulse pressure
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT01404455
Brief Title
Effect of Wide Pulse Pressure on the Predictability of Stroke Volume Variation for Fluid Responsiveness in Patients Undergoing Off-pump Coronary Artery Bypass Graft
Study Type
Interventional
2. Study Status
Record Verification Date
January 2012
Overall Recruitment Status
Completed
Study Start Date
December 2010 (undefined)
Primary Completion Date
August 2011 (Actual)
Study Completion Date
August 2011 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Severance Hospital
4. Oversight
5. Study Description
Brief Summary
The investigators examined the predictability of stroke volume variation for fluid responsiveness in patients with wide pulse pressure undergoing off-pump coronary artery bypass graft
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Stroke Volume Variation
7. Study Design
Primary Purpose
Screening
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
Participant
Allocation
Non-Randomized
Enrollment
66 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Normal pulse pressure
Arm Type
Other
Arm Description
pulse pressure <60mmHg
Arm Title
Wide pulse pressure
Arm Type
Other
Arm Description
pulse pressure ≥60mmHg
Intervention Type
Other
Intervention Name(s)
HES 130/0.4 (VoluvenⓇ, Fresenius Kabi, Graz, Austria) 500mL loading
Intervention Description
HES 130/0.4 (VoluvenⓇ, Fresenius Kabi, Graz, Austria) 500mL loading during 15 minutes after induction of anesthesia
Primary Outcome Measure Information:
Title
The predictability of stroke volume variation for fluid responsiveness in patients with wide pulse pressure
Time Frame
30 min
Secondary Outcome Measure Information:
Title
Cut off value of stroke volume variation for predicting fluid responsiveness in patients with wide pulse pressure
Time Frame
30 min
10. Eligibility
Sex
All
Minimum Age & Unit of Time
20 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
1. Age ≥ 20
2. elective off-pump coronary artery bypass graft
Exclusion Criteria:
1. arrhythmia
2.EF <40%
3.valvular heart dz
4.pul HTN
5.PAOD
6.lung dz
7.NYHA IV
8.ESRD
Facility Information:
Facility Name
Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine
City
Seoul
ZIP/Postal Code
120-752
Country
Korea, Republic of
12. IPD Sharing Statement
Learn more about this trial
Effect of Wide Pulse Pressure on the Predictability of Stroke Volume Variation for Fluid Responsiveness in Patients Undergoing Off-pump Coronary Artery Bypass Graft
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