Back to resultsIron Metabolism in Dragon Boat Athletes
Primary Purpose
Anaemia
Status
Completed
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
specific dragon boating training intervention
specific dragon boat intervention
Sponsored by
About this trial
This is an interventional diagnostic trial for Anaemia focused on measuring iron metabolism, hepcidin, dragon boating, sport-specific stress, iron, anaemia, sport
Eligibility Criteria
Inclusion Criteria:
- athletes performing dragon boat sport
Exclusion Criteria:
- acute clinically significant intercurrent diseases
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm Type
Active Comparator
Active Comparator
Arm Label
sports intervention male
sports intervention women
Arm Description
male athletes of the german national dragon boat team
women athletes of the german national dragon boat team
Outcomes
Primary Outcome Measures
change from Baseline in prohepcidin after performing dragonboating
one meassurement of prohepcidin immediate before and within three hours after performing two to four specific dragonboat interventions at the same day
Secondary Outcome Measures
haematocrit
one meassurement of haematocrit immediate before and within three hours after performing two to four specific dragonboat intervention at the same day
value of reticulocytes
one meassurement of reticulocytes immediate before performing two to four specific dragonboat interventions
value of hypochromic erythrocytes
one meassurement of hypochromic erythrocytes immediate before performing two to four specific dragonboat interventions
change from Baseline in serum iron after performing dragonboating
one meassurement of serum iron immediate before and within three hours after performing two to four specific dragonboat interventions at the same day
value of transferrin
one meassurement of transferrin immediate before performing two to four specific dragonboat interventions
value of transferrin saturation
one meassurement of transferrin saturation immediate before performing two to four specific dragonboat interventions
value of ferritin
one meassurement of ferritin immediate before performing two to four specific dragonboat interventions
change from Baseline in hepcidin after performing dragonboating
one meassurement of hepcidin immediate before and within three hours after performing two to four specific dragonboat interventions at the same day
Full Information
NCT ID
NCT01431118
First Posted
August 31, 2011
Last Updated
July 21, 2012
Sponsor
University of Giessen
Collaborators
MVZ für Laboratoriumsmedizin Koblenz, Deutscher Drachenboot Verband e.V.
1. Study Identification
Unique Protocol Identification Number
NCT01431118
Brief Title
Iron Metabolism in Dragon Boat Athletes
Official Title
Iron Metabolism in Dragon Boat Athletes - An Analysis of Changes in Blood Count Parameters Under Sport-specific Stress
Study Type
Interventional
2. Study Status
Record Verification Date
July 2012
Overall Recruitment Status
Completed
Study Start Date
April 2011 (undefined)
Primary Completion Date
April 2012 (Actual)
Study Completion Date
April 2012 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
University of Giessen
Collaborators
MVZ für Laboratoriumsmedizin Koblenz, Deutscher Drachenboot Verband e.V.
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
The purpose of the study is:
To investigate the effect of sport-specific stress in the iron metabolism of dragon boat athletes
To investigate the effects of sport-specific stress in the activity of pro-hepcidin and hepcidin
Detailed Description
This investigation evaluates the effects of sport-specific stress in iron metabolism of dragon boat athletes. Recent studies showed a significant increase in hepcidin activity under exercise (Röcker L. et al.(2005): Iron regulatory protein hepcidin is increased in female athletes after a marathon. European Journal of Applied Physiology, S. 95, 569-571)which possibly influences the iron metabolism.
In particular in this investigation the activity of pro-hepcidin and hepcidin under sport-specific stress is analysed. Therefore elite dragonboat athletes will be included to this study. Every athlete is tested once. At one exercise day from every athlete the iron metabolism especially the change of hepcidin, prohepcidin and iron before and after a specific dragonboat intervention is analysed.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Anaemia
Keywords
iron metabolism, hepcidin, dragon boating, sport-specific stress, iron, anaemia, sport
7. Study Design
Primary Purpose
Diagnostic
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
Investigator
Allocation
Non-Randomized
Enrollment
40 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
sports intervention male
Arm Type
Active Comparator
Arm Description
male athletes of the german national dragon boat team
Arm Title
sports intervention women
Arm Type
Active Comparator
Arm Description
women athletes of the german national dragon boat team
Intervention Type
Other
Intervention Name(s)
specific dragon boating training intervention
Intervention Description
male athletes of the german national dragon boat team performing three specific training units at one day
Intervention Type
Other
Intervention Name(s)
specific dragon boat intervention
Intervention Description
women athletes of the german national dragon boat team performing two specific training units and one weight lifting test at one day
Primary Outcome Measure Information:
Title
change from Baseline in prohepcidin after performing dragonboating
Description
one meassurement of prohepcidin immediate before and within three hours after performing two to four specific dragonboat interventions at the same day
Time Frame
pre and post exercise intervention at the same day
Secondary Outcome Measure Information:
Title
haematocrit
Description
one meassurement of haematocrit immediate before and within three hours after performing two to four specific dragonboat intervention at the same day
Time Frame
pre and post exercise intervention at the same day
Title
value of reticulocytes
Description
one meassurement of reticulocytes immediate before performing two to four specific dragonboat interventions
Time Frame
pre exercise
Title
value of hypochromic erythrocytes
Description
one meassurement of hypochromic erythrocytes immediate before performing two to four specific dragonboat interventions
Time Frame
pre exercise
Title
change from Baseline in serum iron after performing dragonboating
Description
one meassurement of serum iron immediate before and within three hours after performing two to four specific dragonboat interventions at the same day
Time Frame
pre and post exercise intervention at the same day
Title
value of transferrin
Description
one meassurement of transferrin immediate before performing two to four specific dragonboat interventions
Time Frame
pre exercise
Title
value of transferrin saturation
Description
one meassurement of transferrin saturation immediate before performing two to four specific dragonboat interventions
Time Frame
pre exercise
Title
value of ferritin
Description
one meassurement of ferritin immediate before performing two to four specific dragonboat interventions
Time Frame
pre exercise
Title
change from Baseline in hepcidin after performing dragonboating
Description
one meassurement of hepcidin immediate before and within three hours after performing two to four specific dragonboat interventions at the same day
Time Frame
pre and post exercise intervention at the same day
10. Eligibility
Sex
All
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
athletes performing dragon boat sport
Exclusion Criteria:
acute clinically significant intercurrent diseases
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Andree Hillebrecht, Dr. med.
Organizational Affiliation
Department of sportsmedicine- University Giessen
Official's Role
Principal Investigator
12. IPD Sharing Statement
Learn more about this trial
Iron Metabolism in Dragon Boat Athletes
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