Feasibility Trial to Maintain Normal Cerebral Oxygen Saturation in High-Risk Cardiac Surgery (Tête-à-coeur)
Cerebral Hypoxia
About this trial
This is an interventional prevention trial for Cerebral Hypoxia focused on measuring cerebral, hypoxia
Eligibility Criteria
Inclusion Criteria:
- Patients with EUROSCORES ≥ 10.
- Planned complex surgery including more than one procedure, or redo procedures.
- Patient able to read and understand the consent form.
- Patients ≥ 18 years of age.
Exclusion Criteria:
- High risk patients undergoing of off pump coronary artery bypass.
- Emergency surgeries less than 6 hours from diagnosis.
- Patient unable to read and understand the consent form.
- Patients with and IABP or a ventricular assist device
- Planned circulatory arrest
- Planned surgery of the descending aorta.
- Patients with acute endocarditis.
Sites / Locations
- Montreal Heart Institute
Arms of the Study
Arm 1
Arm 2
Active Comparator
No Intervention
Intervention
Control
an alarm threshold at a value of 90% of the resting baseline cerebral saturation value (baseline - 10%) will be established. To minimize the probability of patients reaching significant decreases rSO2 values, interventions to improve cerebral oxygenation will be initiated according to the strategies described in the algorithm. The success and failure of these interventions will be noted. As in the Control group, the screen will remain blinded in the ICU and the intensivist will not see the values.
the cerebral oxymetry screen will be blinded and changes in NIRS values will be unknown to the anesthesiologist. The management of the case will proceed as per normal local practice. The screen will remain blinded in the ICU and the intensivist will not see the values.