Effects of Different Exercise Training Regimens on Visceral Fat Dynamic and Resting Energy Expenditure in Obese Patients
Abdominal Obesity
About this trial
This is an interventional treatment trial for Abdominal Obesity focused on measuring Abdominal Obesity, training, fat, insulin, glucose, diet
Eligibility Criteria
Inclusion Criteria:
- BMI >= 35 kg/m2
- waist circumference >102cm (men), >88cm (women)
- age 18 - 60 years
- written informed consent
Exclusion Criteria:
- type 1 or type 2 diabetes
- fasting plasma glucose >= 6.0 mmol/l
- 2h-OGTT (oral glucose tolerance test) glucose >= 11.1 mmol/l
- any chronic inflammatory or malignant disease
- medical treatment which influences glucose metabolism
- drug or alcohol abuse
- psychiatric disorders
- untreated thyroid dysfunction
- cardiac pacemaker or other contraindication for MRI
- attendant therapy with oral antidiabetic medication, GLP-1 mimetics or analoga, Insulin, anti-obesity medication (orlistat, sibutramine), Falithrom, antipsychotic drugs, any chemotherapeutics
- pregnant or nursing women
- expected low compliance
- current participation in another investigational trial
- last exercise training <= 6 months ago
Sites / Locations
- University of Leipzig, Department of MedicineRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
endurance training
strength training
Endurance training: Supervised, twice a week, each training session consists of a 20 min warm up and cool down period and a minimum of 40min tread mill, rawing device or bicycle training. During the study period of 24 months, we will perform an open randomized, prospective training intervention study comparing the effects of three times a week either strength or endurance training on reduction of visceral fat area as determined by MRI scans at the level of L4-L5.
Strength training: Supervised, twice a week, each training session consists of a 20 min warm up and cool down period and a minimum of 40min circle training During the study period of 24 months, we will perform an open randomized, prospective training intervention study comparing the effects of two to three times a week either strength or endurance training on reduction of visceral fat area as determined by MRI scans at the level of L4-L5.