Developing Cognitive Training for Tourette Syndrome
Tourette Syndrome, Chronic Tic Disorders
About this trial
This is an interventional treatment trial for Tourette Syndrome focused on measuring tic disorder, tourette syndrome, habit reversal, response inhibition, cognitive retraining
Eligibility Criteria
Inclusion Criteria:
- age between 9 and 17
- a diagnosis of TS or chronic tic disorder on the structured diagnostic interview
- moderate to severe levels of tic symptoms (YGTSS total score > 13 for TS, or > 9 for CTD), and (d) IQ > 80.
Exclusion Criteria:
- current substance abuse or dependence
- current or past psychotic disorder, bipolar disorder, or schizophrenia
- 4 or more previous sessions of behavioral treatments for tic
- significant suicidal ideation and/or attempts within the past 3 months
- any recent (in the previous month) or planned change in medication for tic symptoms.
Sites / Locations
- The Psychology Clinic, University of Wisconsin-Milwaukee
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
CBIT + Response Inhibition Training
Experimental: CBIT + Placebo Computer Training
CBIT is an 8 session treatment protocol held over 10 weeks. In CBIT, core components are implemented across the various therapy sessions. These core components include habit reversal training (HRT), functional assessment/function-based interventions, and a behavioral reward program for the child. Each core component is briefly described below. HRT/CBIT involves three components, awareness training, competing response training, and social support training (Woods, Twohig, Roloff, & Flessner, 2003). For this condition, CBIT will be combined with adjunctive computerized response inhibition training, which will be delivered over the first 4 weeks of the CBIT treatment.
In this condition, participants receive the same package of CBIT treatment, which consists of awareness training, competing response training, and social support training (Woods, Twohig, Roloff, & Flessner, 2003). Additionally, the standard CBIT treatment is combined with computer-based placebo cognitive training that is irrelevant to the target cognitive ability (i.e., response inhibition). During the first 4 weeks of the CBIT treatment, participants will receive 8 sessions of placebo cognitive training.