Strength Training for ARthritis Trial (START)
Knee Osteoarthritis
About this trial
This is an interventional treatment trial for Knee Osteoarthritis focused on measuring Arthritis, Osteoarthritis, Strength Training
Eligibility Criteria
Inclusion Criteria:
- Mild to Moderate Knee Osteoarthritis
Exclusion Criteria:
- BMI <20 kg/m2 and ≥45 kg/m2
- Knee varus malalignment
- Participation in formal strength training for more than 30 min/week in the past 6 months.
Sites / Locations
- Wake Forest University
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
Active Comparator
High Intensity Strength Training
Low Intensity Strength Training
Attention Control
The strength-training intervention will consist of 5-min warm-up, 40-min training, and 15-min cool-down. The 60-min sessions will be conducted 3 times/wk for 18 months. Every 2 weeks the load lifted will be adjusted so that the participants in this group are lifting 3 sets of each exercise at 75-90% of 1RM.
The strength-training intervention will consist of 5-min warm-up, 40-min training, and 15-min cool-down. The 60-min sessions will be conducted 3 times/wk for 18 months. Every 2 weeks the load lifted will be adjusted so that the participants are lifting 3 sets of 15 repetitions at 30-40% of 1RM.
Participants in the control group will attend 60-min organized workshops 2 times/month for the first 6 months and then 1 time/month for months 7-18. Over the 18 months interactive presentations will cover such topics as foot care, nutrition, managing medication, and sleep practices, and experts will give wide-ranging lectures.