A-priori Versus Provisional Heparin on Radial Artery Occlusion After Transradial Coronary Angiography and Patent Hemostasis (PHARAOH)
Coronary Artery Disease
About this trial
This is an interventional prevention trial for Coronary Artery Disease focused on measuring radial artery occlusion, hemostasis, coronary intervention, radial approach
Eligibility Criteria
Inclusion Criteria:
- all diagnostic cardiac cath patients
Exclusion Criteria:
- warfarin therapy
- previous ipsilateral TRA
- lack of consent
- abnormal (type D) Barbeau test
- scleroderma
- thrombocytopenia
- or other contraindications to heparin
Sites / Locations
- Commonwealth Medical College,
- IUCPQ
- Sheth VS General Hospital,
Arms of the Study
Arm 1
Arm 2
No Intervention
Experimental
Compression without adjustment
Patent hemostasis & heparin
TR band (Terumo medical) applied. The TR band is then deflated gradually till pulsatile bleeding is observed under the transparent plastic inflatable chamber and then 1-2 cc of air is placed back in the TR band chamber to stop bleeding. The band is left in place for 2 hours and not adjusted further unless patient complained of symptoms or bleeding occurred.
TR-band is placed and positioned similarly to the other study arm. However, in theses cases, patency is evaluated at the time of application of the TR-band, and monitored every 15 minutes afterwards till the band is removed and hemostasis completed. After TR-band placement, if maintenance of radial artery patency is obtained, no heparin is administered and TR band is left in place for 1-hour. If radial artery patency is not maintained, a bolus of heparin 50 U/kg or a maximum of 5000 units is administered and the band is left in place for 2 hours.