Prevalence of Dissociative Disorders in Children
Primary Purpose
Dissociative Disorders, Schizophrenia
Status
Completed
Phase
Not Applicable
Locations
France
Study Type
Interventional
Intervention
Primary stage
Secondary stage
Sponsored by
About this trial
This is an interventional diagnostic trial for Dissociative Disorders focused on measuring children dissociative disorders schizophrenia
Eligibility Criteria
Inclusion Criteria:
- 7 to 18 years
- Supported in the partner institutions of the study
- IQ>35 on the certificate of orientation of the Maison Départementale des Personnes Handicapées (MDPH)
- Obtaining the agreement of parents and children
Exclusion Criteria:
- QI<35 on the certificate file Guidance MDPH
- Children not speaking french
Sites / Locations
- Psychiatrie infanto-juvénile - Centre Hospitalier d'Antibes
- Psychiatrie infanto-juvénile-Pôle femme-mère -enfant
- Service de psychiatrie de l'enfant et de l'adolescent
- Service de psychiatrie de l'enfant et de l'adolescent
Arms of the Study
Arm 1
Arm Type
Experimental
Arm Label
Children with Dissociative Disorders
Arm Description
Children will take first the primary stage. If one child is positive, he will pass the secondary stage.
Outcomes
Primary Outcome Measures
Rate of children diagnosed with dissociative disorders
Rate of children diagnosed with dissociative disorders: children positive for the test Kiddie-Schedule for Affective Disorders and Schizophrenia (Kiddie-SADS).
Secondary Outcome Measures
Percentage of children positive for test: Autism Diagnostic Interview-Revise (ADI-R).
Scores of three dimensions of schizophrenia in the Positive And Negative Syndrome Scale (PANSS)
3 dimensions: positive symptoms, negative symptoms and general psychopathology, based on these scores the diagnostic subtype of schizophrenia is established.
Score at the Test Lillois de Communication (TLC)
Score on the Wechsler Intelligence Scale for Children-Fourth Edition (WISC IV)subtests and overall intelligence quotient (IQ).
Response time to test verbal fluency, scores on the Trail Making Test A (TMT) and TMT B.
Full Information
NCT ID
NCT01512641
First Posted
December 13, 2011
Last Updated
January 31, 2014
Sponsor
Centre Hospitalier Universitaire de Nice
1. Study Identification
Unique Protocol Identification Number
NCT01512641
Brief Title
Prevalence of Dissociative Disorders in Children
Official Title
Prevalence of Dissociative Disorders in Children in a Population Supported in the Medico-social and Health Structures in Provence Alpes Cote d'Azur
Study Type
Interventional
2. Study Status
Record Verification Date
January 2014
Overall Recruitment Status
Completed
Study Start Date
December 2011 (undefined)
Primary Completion Date
May 2013 (Actual)
Study Completion Date
May 2013 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Centre Hospitalier Universitaire de Nice
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
Schizophrenia beginning before 18 years is a clinical entity not well known because of its low incidence and difficulties in the clinical diagnosis.
However, in the investigators clinical practice, due to the specialization of the investigators service, the investigators are led to hospital to receive important feel active of patients meeting the Diagnostic and Statistical Manual of Mental Disorders IV text revision (DSM IV-TR) precose schizophrenia.
The work of us team on the theme of the relationship between Pervasive Developmental Disorders and precose Schizophrenia led us to hypothesize that a number of children in care in the medical and educational institutes, hospitals and day shelters therapeutic part-time symptoms of schizophrenia or a line real early diagnosis of schizophrenia undervalued or not diagnosed.
The main goal is to estimate the prevalence of dissociative disorders in a population of children in care institutions and medical education in child psychiatry in hospitals and others structures.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Dissociative Disorders, Schizophrenia
Keywords
children dissociative disorders schizophrenia
7. Study Design
Primary Purpose
Diagnostic
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
301 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Children with Dissociative Disorders
Arm Type
Experimental
Arm Description
Children will take first the primary stage. If one child is positive, he will pass the secondary stage.
Intervention Type
Other
Intervention Name(s)
Primary stage
Intervention Description
Kiddie-Schedule for Affective Disorders and Schizophrenia
Intervention Type
Other
Intervention Name(s)
Secondary stage
Intervention Description
children who are positive to the kiddie-SADS (primary stage), will take the tests: PANSS, Scale for the Assessment of Negative Symptoms (SANS), ADI-R, scale TLC and WISC IV
Primary Outcome Measure Information:
Title
Rate of children diagnosed with dissociative disorders
Description
Rate of children diagnosed with dissociative disorders: children positive for the test Kiddie-Schedule for Affective Disorders and Schizophrenia (Kiddie-SADS).
Time Frame
between 2 and 4 hours depending children
Secondary Outcome Measure Information:
Title
Percentage of children positive for test: Autism Diagnostic Interview-Revise (ADI-R).
Time Frame
1 day on average
Title
Scores of three dimensions of schizophrenia in the Positive And Negative Syndrome Scale (PANSS)
Description
3 dimensions: positive symptoms, negative symptoms and general psychopathology, based on these scores the diagnostic subtype of schizophrenia is established.
Time Frame
4 hours
Title
Score at the Test Lillois de Communication (TLC)
Time Frame
30 minutes
Title
Score on the Wechsler Intelligence Scale for Children-Fourth Edition (WISC IV)subtests and overall intelligence quotient (IQ).
Time Frame
4 hours
Title
Response time to test verbal fluency, scores on the Trail Making Test A (TMT) and TMT B.
Time Frame
30 minutes
10. Eligibility
Sex
All
Minimum Age & Unit of Time
7 Years
Maximum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
7 to 18 years
Supported in the partner institutions of the study
IQ>35 on the certificate of orientation of the Maison Départementale des Personnes Handicapées (MDPH)
Obtaining the agreement of parents and children
Exclusion Criteria:
QI<35 on the certificate file Guidance MDPH
Children not speaking french
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Florence ASKENAZY, PU-PH
Organizational Affiliation
University hospital of Nice
Official's Role
Study Director
First Name & Middle Initial & Last Name & Degree
Emmanuelle DOR, PH
Organizational Affiliation
University hospital of Nice
Official's Role
Principal Investigator
First Name & Middle Initial & Last Name & Degree
François POINSO, PU-PH
Organizational Affiliation
AP-HM
Official's Role
Principal Investigator
First Name & Middle Initial & Last Name & Degree
Michèle BATTISTA, PH
Organizational Affiliation
Frejus's hospital
Official's Role
Principal Investigator
First Name & Middle Initial & Last Name & Degree
Michel BOUBLIL, PH
Organizational Affiliation
Antibes's hospital
Official's Role
Principal Investigator
Facility Information:
Facility Name
Psychiatrie infanto-juvénile - Centre Hospitalier d'Antibes
City
Antibes
ZIP/Postal Code
06600
Country
France
Facility Name
Psychiatrie infanto-juvénile-Pôle femme-mère -enfant
City
Fréjus
ZIP/Postal Code
83608
Country
France
Facility Name
Service de psychiatrie de l'enfant et de l'adolescent
City
Marseille
ZIP/Postal Code
13009
Country
France
Facility Name
Service de psychiatrie de l'enfant et de l'adolescent
City
Nice
ZIP/Postal Code
06000
Country
France
12. IPD Sharing Statement
Citations:
PubMed Identifier
32716957
Citation
Dor-Nedonsel E, Menard ML, Fernandez A, Sakarovitch C, Fontas E, Salle-Collemiche X, Poinso F, Tosello AL, Maria F, Manera V, Askenazy F, Thummler S. Early-Onset Schizophrenia in a paediatric population of French psychiatric and medico-social care centres: A cross sectional study. PLoS One. 2020 Jul 27;15(7):e0236241. doi: 10.1371/journal.pone.0236241. eCollection 2020.
Results Reference
derived
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Prevalence of Dissociative Disorders in Children
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