Plasma Glucose Levels With Dexamethasone as Adjuvant to Interscalene Block
Shoulder Pain, Injury of Shoulder Region, Disorder of Shoulder
About this trial
This is an interventional treatment trial for Shoulder Pain focused on measuring Blood Glucose, Bupivacaine, Interscalene Nerve Block, Regional Anesthesia, Pain Blockade, Arthroscopic Surgery, Arthroscopic rotator cuff repair, Dexamethasone, Anti-Inflammatory Agents, Therapeutic Uses, Physiological Effects of Drugs, Glucocorticoids, Anesthetics, Local, Anesthetics, Sensory System Agents, Adjuvants, Anesthesia, Anesthesiology, Injections, Adult, Analgesia/methods, Brachial Plexus/drug effects, Brachial Plexus/surgery, Brachial Plexus/ultrasonography, Bupivacaine/administration & dosage, Dexamethasone/administration & dosage, Drug Therapy, Combination, Female, Humans, Male, Nerve Block/methods, Pain, Postoperative/etiology, Pain, Postoperative/prevention & control, Prospective Studies, Time Factors
Eligibility Criteria
Inclusion Criteria:
- ASA 1 or ASA 2 male or female non pregnant patients undergoing elective shoulder arthroscopy for surgical repair.
Exclusion Criteria:
- severe lung disease
- contralateral diaphragmatic paralysis
- coagulopathy
- pregnancy
- pre-existing neuropathy involving the surgical limb
- systemic use of corticosteroids for 2 weeks or longer within 6 months of surgery
- chronic opioid use (30 mg oral oxycodone equivalent per day)
- diabetes I or II
- diagnosis of "pre-diabetes"
- currently prescribed any of the oral glucose medications :sulfonylureas, meglitinides, biguanides, thiazolidinediones, alpha-glucosidase inhibitors, or DPP-4 inhibitors.
Sites / Locations
- Newport Hospital
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Bupivacaine
Dexamethasone and Bupivacaine
50 randomized participants in group receive 20cc 0.25% bupivacaine injected perineurally for interscalene nerve block.
50 randomized participants in group will 8 mg(2cc of 4mg/cc solution) Dexamethasone added to 20 cc 0.25% bupivacaine in one syringe resulting in 364 µgm/cc for injection. Injected perineurally for interscalene nerve block pre-operatively.