Quiting Marijuana Use: Self-report Study of Quitting Straegies and Withdrawal Symptoms
Primary Purpose
Cannabis Abuse, Cannabis Dependence
Status
Completed
Phase
Locations
United States
Study Type
Observational
Intervention
Sponsored by
About this trial
This is an observational trial for Cannabis Abuse focused on measuring Cannabis, Craving, Questionnaire, Non-Treatment, Drug Use
Eligibility Criteria
INCLUSION CRITERIA:
- age 18 or older
- have made at least one attempt to quit marijuana use
- able to give valid informed consent
- ability to understand English
Sites / Locations
- National Institute on Drug Abuse, Biomedical Research Center (BRC)
- Maryland Psychiatric Research Center (MPRC) 55 Wade Avenue
- Medical University of S. Carolina
Outcomes
Primary Outcome Measures
Marijuana Quit Questionnaire
Secondary Outcome Measures
Marijuana Craving Questionnaire, and Additional Questions about Marijuana Craving
Full Information
NCT ID
NCT01603992
First Posted
May 19, 2012
Last Updated
April 4, 2018
Sponsor
National Institute on Drug Abuse (NIDA)
1. Study Identification
Unique Protocol Identification Number
NCT01603992
Brief Title
Quiting Marijuana Use: Self-report Study of Quitting Straegies and Withdrawal Symptoms
Official Title
Quitting Marijuana Use: Self-Report Study of Quitting Strategies and Withdrawal Symptoms
Study Type
Observational
2. Study Status
Record Verification Date
May 3, 2012
Overall Recruitment Status
Completed
Study Start Date
November 8, 2005 (undefined)
Primary Completion Date
undefined (undefined)
Study Completion Date
May 3, 2012 (undefined)
3. Sponsor/Collaborators
Name of the Sponsor
National Institute on Drug Abuse (NIDA)
4. Oversight
5. Study Description
Brief Summary
Background:
- Marijuana is the most widely used illicit drug in the world, yet relatively little is known about users who try to quit without formal treatment ( spontaneous quitting). Studies have suggested that there are some common strategies that many individuals use in spontaneous quitting, such as changing one s lifestyle or identity, reminding oneself of negative consequences, support from family and friends, and religion. However, more research is needed to determine potential treatment strategies for marijuana use.
Objectives:
To identify strategies used to help with marijuana quitting among non-treatment seeking adult marijuana users.
To identify withdrawal symptoms experienced during marijuana quitting and their relationship to the quitting strategies used and the outcome of the quit attempt.
To evaluate whether subgroups of marijuana users differ in their experience of marijuana quitting.
Eligibility:
- Individuals at least 18 years of age who have made at least one attempt to quit marijuana use.
Design:
The study will consist of one visit of approximately 1 to 2 hours.
Participants will fill out three questionnaires. The questionnaires have different types of questions, and will ask about background and lifestyle, marijuana use and craving patterns and behaviors, and difficulties in previous attempts to quit using marijuana.
Detailed Description
Marijuana is the most widely used illicit drug in the world, yet relatively little is known about users who try to quit without formal treatment (so-called spontaneous quitting). This study will use two self-report questionnaires to collect information on the socio-demographic characteristics, marijuana use history, most difficult marijuana quit experience, and marijuana craving from a convenience sample of 1230 adult, non-treatment-seeking marijuana users. The questionnaires take 45-60 minutes to administer. Data will be analyzed for patterns and correlations among the characteristics of the quit attempt, including any withdrawal symptoms, quitting strategies used, and its success. The marijuana craving data will be analyzed to evaluate the validity of this measure of marijuana craving. There are no direct benefits to subjects from study participation. The scientific benefit is an improved understanding of spontaneous quitting of marijuana use, which may lead to improved interventions for marijuana users in the future. There are no physical risks to subjects. There are risks of anxiety or embarrassment while taking the questionnaire and of loss of confidentiality of sensitive information collected about subjects.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Cannabis Abuse, Cannabis Dependence
Keywords
Cannabis, Craving, Questionnaire, Non-Treatment, Drug Use
7. Study Design
Enrollment
822 (Actual)
Primary Outcome Measure Information:
Title
Marijuana Quit Questionnaire
Time Frame
1 to 2 hours
Secondary Outcome Measure Information:
Title
Marijuana Craving Questionnaire, and Additional Questions about Marijuana Craving
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
INCLUSION CRITERIA:
age 18 or older
have made at least one attempt to quit marijuana use
able to give valid informed consent
ability to understand English
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
David A Gorelick, M.D.
Organizational Affiliation
National Institute on Drug Abuse (NIDA)
Official's Role
Principal Investigator
Facility Information:
Facility Name
National Institute on Drug Abuse, Biomedical Research Center (BRC)
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21224
Country
United States
Facility Name
Maryland Psychiatric Research Center (MPRC) 55 Wade Avenue
City
Catonsville
State/Province
Maryland
ZIP/Postal Code
21228
Country
United States
Facility Name
Medical University of S. Carolina
City
Charleston
State/Province
South Carolina
ZIP/Postal Code
29425
Country
United States
12. IPD Sharing Statement
Citations:
PubMed Identifier
15385225
Citation
Adamson SJ, Sellman JD. A prototype screening instrument for cannabis use disorder: the Cannabis Use Disorders Identification Test (CUDIT) in an alcohol-dependent clinical sample. Drug Alcohol Rev. 2003 Sep;22(3):309-15. doi: 10.1080/0959523031000154454.
Results Reference
background
PubMed Identifier
15804875
Citation
Boyd SJ, Tashkin DP, Huestis MA, Heishman SJ, Dermand JC, Simmons MS, Gorelick DA. Strategies for quitting among non-treatment-seeking marijuana smokers. Am J Addict. 2005 Jan-Feb;14(1):35-42. doi: 10.1080/10550490590899835.
Results Reference
background
PubMed Identifier
15514394
Citation
Budney AJ, Hughes JR, Moore BA, Vandrey R. Review of the validity and significance of cannabis withdrawal syndrome. Am J Psychiatry. 2004 Nov;161(11):1967-77. doi: 10.1176/appi.ajp.161.11.1967.
Results Reference
background
PubMed Identifier
23969281
Citation
Koola MM, Boggs DL, Kelly DL, Liu F, Linthicum JA, Turner HE, McMahon RP, Gorelick DA. Relief of cannabis withdrawal symptoms and cannabis quitting strategies in people with schizophrenia. Psychiatry Res. 2013 Oct 30;209(3):273-8. doi: 10.1016/j.psychres.2013.07.044. Epub 2013 Aug 20.
Results Reference
derived
PubMed Identifier
23146560
Citation
Boggs DL, Kelly DL, Liu F, Linthicum JA, Turner H, Schroeder JR, McMahon RP, Gorelick DA. Cannabis withdrawal in chronic cannabis users with schizophrenia. J Psychiatr Res. 2013 Feb;47(2):240-5. doi: 10.1016/j.jpsychires.2012.10.010. Epub 2012 Nov 10.
Results Reference
derived
Learn more about this trial
Quiting Marijuana Use: Self-report Study of Quitting Straegies and Withdrawal Symptoms
We'll reach out to this number within 24 hrs