Back to resultsFemoroacetabular Impingement RandomiSed Controlled Trial (FIRST)
Primary Purpose
Femoroacetabular Impingement
Status
Completed
Phase
Not Applicable
Locations
International
Study Type
Interventional
Intervention
Arthroscopic Lavage
Arthroscopic Osteochondroplasty
Sponsored by
About this trial
This is an interventional treatment trial for Femoroacetabular Impingement focused on measuring FAI, randomized, hip arthroscopy, lavage, osteochondroplasty
Eligibility Criteria
Inclusion Criteria:
- Adult men or women ages 18 to 50 years
- Hip pain for greater than 6 months with no relief from non-operative means (physiotherapy, non-steroidal anti-inflammatory medication, rest)
- Documentation of failed physiotherapy, including core conditioning of the hip, back, and abdomen
- CAM or Mixed Type FAI as diagnosed on x-rays and magnetic resonance imaging (MRI) or magnetic resonance arthrogram (MRA)
- Temporary relief from an intra-articular hip injection
- Informed consent from participant
- Ability to speak, understand and read in the language of the clinical site
Exclusion Criteria:
- Previous inclusion in a study involving FAI
- Evidence of hip dysplasia (centre edge angle less than 20)
- Presence of advanced hip osteoarthritis (Tonnis Grade 2 or 3)
- Presence of other hip syndromes (concurrent non-FAI related pathology)
- Previous trauma to the affected hip
- Previous surgery on the affected hip or contralateral hip
- Severe acetabular deformities (e.g. acetabular protrusion, coxa profunda, circumferential labral ossification)
- Immunosuppressive medication use
- Chronic pain syndromes
- Significant medical co-morbidities (requiring daily assistance for ADLs)
- History of paediatric hip disease (Legg-Calve-Perthes; slipped capital femoral epiphysis)
- Ongoing litigation or compensation claims secondary to hip problems
Any other reasons given to exclude the patient
- If a patient does not meet the eligibility criteria for the FIRST trial, they may be considered eligible for the FIRST-EPIC sub-study.
Sites / Locations
- Dalhousie University
- McMaster University
- Kingston General Hospital
- Fowler Kennedy Sports Medicine Clinic
- London Health Sciences
- St. Michael's Hospital
- CHU de Québec, L'Hôtel-Dieu de Québec
- Odense University Hospital
- Hatanpää Hospital
- Turku University Hospital
Arms of the Study
Arm 1
Arm 2
Arm Type
Active Comparator
Experimental
Arm Label
Arthroscopic Lavage
Arthroscopic Osteochondroplasty
Arm Description
Participants have three hip portals (antero-lateral, mid anterior, distal antero-lateral) with limited capsulotomy allowing for a complete assessment of the central and peripheral compartments. The participant has a diagnostic arthroscopy and lavage of the hip joint with three litres of normal saline. No osteochondroplasty or rim resection is completed in this group. No instruments are used to treat minor cartilage or labral damage. The labrum should only be repaired if mechanically unstable once probed with visible displacement or chondrolabral separation. The labrum will be refixated only if the above criteria for labral instability is met.
After establishing standard portals, an inter-portal capsulotomy will be completed to allow for complete evaluation of the central compartment of the hip. Significant and obvious labral tears and cartilage damage will be addressed. The labrum will be repaired if mechanically unstable once probed with visible displacement or chondrolabral separation. The acetabular rim will be evaluated and any evident Pincer lesion will be resected using an arthroscopic burr under fluoroscopic guidance. Following this resection, the labrum will be refixated only if the criteria for labral instability is met. Following this, a limited capsulotomy will be completed along the head-neck junction of the femoral neck to allow for visualization and treatment of the impingement lesion in the peripheral compartment. For the FIRST-EPIC sub-study, participants will receive the osteochondroplasty intervention as per standard of care.
Outcomes
Primary Outcome Measures
Pain (measured using a Visual Analog Scale)
The VAS is one of the most frequently used pain rating scales in clinical practice and research. The VAS is a validated unidimensional scale that is easy to use, requires no verbal or reading skills, and is sufficiently versatile to be employed in a variety of settings. The VAS will be administered during routine follow up visits at baseline, 2 weeks, 6 weeks, 3 months, 6 months, and 12 months.
Secondary Outcome Measures
Function (measured using the Hip Outcome Score)
The HOS is a self-administered hip score that was designed to capture hip function and outcomes following surgical therapies such as arthroscopy. The HOS has been shown to have the greatest clinimetric evidence for use in patients with FAI or labral tears.
Health-related quality of life (measured using the Short-Form 12)
The SF-12 may be self or interview-administered and will help document general health status as well as the burden of illness that FAI presents.
Function and lifestyle (measured using the International Hip Outcome Tool)
The iHOT-12 is a shorter version of the iHOT-33 designed to be easier to complete in routine clinical practice to measure both health-related quality of life and changes after treatment in young, active patients with hip disorders. This questionnaire has been shown to be valid, reliable, and responsive to change.
Health utility (measured using the Euro-Quol 5 Dimensions)
The EQ-5D is a standardized instrument for use as a measure of health outcome. The EQ-5D comprises five dimensions of health (mobility, self-care, usual activities, pain/discomfort, and anxiety/depression). The EQ-5D has been used in previous studies involving patients with hip pain and has been extensively validated. Our decision to the use EQ-5D was based upon our interest in collecting health utility data for a formal economic analysis.
Urinary function (measured using the Male/Female Lower Urinary Tract Symptoms questionnaires)
The two validated questionnaires selected that pertain to male and female urinary symptoms are gender specific variations of the International Consultation on Continence Questionnaire (ICIQ). The ICIQ-MLUTS (male) and ICIQ-FLUTS (female). These are validated patient-completed questionnaires, which evaluate male and female lower urinary tract symptoms (LUTS), as well as quality of life. Both questionnaires have demonstrated validity, reliability and responsiveness internally and externally.
Sexual function (measured using the International Index of Erectile Dysfunction and the Female Sexual Function Index)
The FSFI is a brief psychometrically sound and reliable tool that assesses female sexual function, and has proven ability to discriminate between clinical and nonclinical populations.The FSFI is also designed to measure the impact on quality of life. The IIEF is a brief self-administered questionnaire assessing sexual experience within the previous 4 weeks, consisting of 15 questions designed to address 5 relevant aspects of male sexual function, specifically erectile function, sexual desire, orgasmic function, intercourse satisfaction and overall satisfaction. This instrument is psychometrically sound with high sensitivity and specificity, which has been validated for administration in research and clinical settings, and across cultures with linguistically validated versions.
Complications / Adverse events
Includes additional surgery, infection, reduced range of motion, and other adverse events
Full Information
NCT ID
NCT01623843
First Posted
June 17, 2012
Last Updated
August 20, 2020
Sponsor
McMaster University
Collaborators
Canadian Institutes of Health Research (CIHR), McMaster Surgical Associates, Canadian Orthopaedic Foundation, American Orthopaedic Society for Sports Medicine
1. Study Identification
Unique Protocol Identification Number
NCT01623843
Brief Title
Femoroacetabular Impingement RandomiSed Controlled Trial
Acronym
FIRST
Official Title
Femoroacetabular Impingement RandomiSed Controlled Trial (FIRST); Sub-study: Femoroacetabular Impingement RandomiSed Controlled Trial With an Embedded Prospective Cohort (FIRST-EPIC)
Study Type
Interventional
2. Study Status
Record Verification Date
August 2020
Overall Recruitment Status
Completed
Study Start Date
September 2012 (Actual)
Primary Completion Date
December 2019 (Actual)
Study Completion Date
March 2020 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
McMaster University
Collaborators
Canadian Institutes of Health Research (CIHR), McMaster Surgical Associates, Canadian Orthopaedic Foundation, American Orthopaedic Society for Sports Medicine
4. Oversight
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
The purpose of this study is to determine whether surgical correction of hip impingement morphology via arthroscopic osteochondroplasty (shaving of bone) will provide improved clinical results (decreased pain and improved function) in adult patients with femoroacetabular impingement (FAI) compared to arthroscopic lavage (washing out of painful inflammation debris) and treating obvious damage of the hip joint.
Detailed Description
Femoroacetabular impingement (FAI) is a condition of the hip where there is a mismatch of the ball and socket in the hip joint. This mismatch creates abnormal contact in the hip which can cause patients to experience hip pain. This can eventually lead to hip damage and osteoarthritis. Hip arthroscopy, a form of minimally invasive surgery has become a popular treatment option. The investigators are conducting a definitive randomized controlled trial (RCT) to determine whether surgical correction of the impingement morphology via arthroscopic osteochondroplasty (shaving of bone) will provide improved clinical results (decreased pain and improved function) in adult FAI patients compared to arthroscopic lavage (washing out of painful inflammation debris) and treating obvious damage of the hip joint.
Like most RCTs, FIRST is designed to demonstrate efficacy (i.e. that an intervention can work theoretically under optimal conditions). In order to address generalizability and improve external validity of the FIRST trial, we are including an external validation cohort using a "RCT with and Embedded ProspectIve Cohort design" (FIRST-EPIC). This pragmatic cohort will allow us to: 1) safeguard against bias attributable to patients declining to take part in the RCT; 2) corroborate or refute whether our efficacy (RCT) population represents the best case scenario (i.e. those with optimal response to osteochondroplasty); 3) evaluate effectiveness of osteochondroplasty and other standard of care treatments for FAI in patients with potentially distinct prognostic factors; and 4) evaluate the cost-effectiveness of the interventions.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Femoroacetabular Impingement
Keywords
FAI, randomized, hip arthroscopy, lavage, osteochondroplasty
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
ParticipantOutcomes Assessor
Allocation
Randomized
Enrollment
220 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Arthroscopic Lavage
Arm Type
Active Comparator
Arm Description
Participants have three hip portals (antero-lateral, mid anterior, distal antero-lateral) with limited capsulotomy allowing for a complete assessment of the central and peripheral compartments. The participant has a diagnostic arthroscopy and lavage of the hip joint with three litres of normal saline. No osteochondroplasty or rim resection is completed in this group. No instruments are used to treat minor cartilage or labral damage. The labrum should only be repaired if mechanically unstable once probed with visible displacement or chondrolabral separation. The labrum will be refixated only if the above criteria for labral instability is met.
Arm Title
Arthroscopic Osteochondroplasty
Arm Type
Experimental
Arm Description
After establishing standard portals, an inter-portal capsulotomy will be completed to allow for complete evaluation of the central compartment of the hip. Significant and obvious labral tears and cartilage damage will be addressed. The labrum will be repaired if mechanically unstable once probed with visible displacement or chondrolabral separation. The acetabular rim will be evaluated and any evident Pincer lesion will be resected using an arthroscopic burr under fluoroscopic guidance. Following this resection, the labrum will be refixated only if the criteria for labral instability is met. Following this, a limited capsulotomy will be completed along the head-neck junction of the femoral neck to allow for visualization and treatment of the impingement lesion in the peripheral compartment. For the FIRST-EPIC sub-study, participants will receive the osteochondroplasty intervention as per standard of care.
Intervention Type
Procedure
Intervention Name(s)
Arthroscopic Lavage
Intervention Description
Lavage: inflammation debris caused from continual friction in the hip is washed out.
Intervention Type
Procedure
Intervention Name(s)
Arthroscopic Osteochondroplasty
Intervention Description
Osteochondroplasty: reshaping the hip ball and socket ("osteoplasty" or "rim trimming").
Primary Outcome Measure Information:
Title
Pain (measured using a Visual Analog Scale)
Description
The VAS is one of the most frequently used pain rating scales in clinical practice and research. The VAS is a validated unidimensional scale that is easy to use, requires no verbal or reading skills, and is sufficiently versatile to be employed in a variety of settings. The VAS will be administered during routine follow up visits at baseline, 2 weeks, 6 weeks, 3 months, 6 months, and 12 months.
Time Frame
12 months
Secondary Outcome Measure Information:
Title
Function (measured using the Hip Outcome Score)
Description
The HOS is a self-administered hip score that was designed to capture hip function and outcomes following surgical therapies such as arthroscopy. The HOS has been shown to have the greatest clinimetric evidence for use in patients with FAI or labral tears.
Time Frame
12 months
Title
Health-related quality of life (measured using the Short-Form 12)
Description
The SF-12 may be self or interview-administered and will help document general health status as well as the burden of illness that FAI presents.
Time Frame
12 months
Title
Function and lifestyle (measured using the International Hip Outcome Tool)
Description
The iHOT-12 is a shorter version of the iHOT-33 designed to be easier to complete in routine clinical practice to measure both health-related quality of life and changes after treatment in young, active patients with hip disorders. This questionnaire has been shown to be valid, reliable, and responsive to change.
Time Frame
12 months
Title
Health utility (measured using the Euro-Quol 5 Dimensions)
Description
The EQ-5D is a standardized instrument for use as a measure of health outcome. The EQ-5D comprises five dimensions of health (mobility, self-care, usual activities, pain/discomfort, and anxiety/depression). The EQ-5D has been used in previous studies involving patients with hip pain and has been extensively validated. Our decision to the use EQ-5D was based upon our interest in collecting health utility data for a formal economic analysis.
Time Frame
12 months
Title
Urinary function (measured using the Male/Female Lower Urinary Tract Symptoms questionnaires)
Description
The two validated questionnaires selected that pertain to male and female urinary symptoms are gender specific variations of the International Consultation on Continence Questionnaire (ICIQ). The ICIQ-MLUTS (male) and ICIQ-FLUTS (female). These are validated patient-completed questionnaires, which evaluate male and female lower urinary tract symptoms (LUTS), as well as quality of life. Both questionnaires have demonstrated validity, reliability and responsiveness internally and externally.
Time Frame
12 months
Title
Sexual function (measured using the International Index of Erectile Dysfunction and the Female Sexual Function Index)
Description
The FSFI is a brief psychometrically sound and reliable tool that assesses female sexual function, and has proven ability to discriminate between clinical and nonclinical populations.The FSFI is also designed to measure the impact on quality of life. The IIEF is a brief self-administered questionnaire assessing sexual experience within the previous 4 weeks, consisting of 15 questions designed to address 5 relevant aspects of male sexual function, specifically erectile function, sexual desire, orgasmic function, intercourse satisfaction and overall satisfaction. This instrument is psychometrically sound with high sensitivity and specificity, which has been validated for administration in research and clinical settings, and across cultures with linguistically validated versions.
Time Frame
12 months
Title
Complications / Adverse events
Description
Includes additional surgery, infection, reduced range of motion, and other adverse events
Time Frame
12 and 24 months
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
50 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Adult men or women ages 18 to 50 years
Hip pain for greater than 6 months with no relief from non-operative means (physiotherapy, non-steroidal anti-inflammatory medication, rest)
Documentation of failed physiotherapy, including core conditioning of the hip, back, and abdomen
CAM or Mixed Type FAI as diagnosed on x-rays and magnetic resonance imaging (MRI) or magnetic resonance arthrogram (MRA)
Temporary relief from an intra-articular hip injection
Informed consent from participant
Ability to speak, understand and read in the language of the clinical site
Exclusion Criteria:
Previous inclusion in a study involving FAI
Evidence of hip dysplasia (centre edge angle less than 20)
Presence of advanced hip osteoarthritis (Tonnis Grade 2 or 3)
Presence of other hip syndromes (concurrent non-FAI related pathology)
Previous trauma to the affected hip
Previous surgery on the affected hip or contralateral hip
Severe acetabular deformities (e.g. acetabular protrusion, coxa profunda, circumferential labral ossification)
Immunosuppressive medication use
Chronic pain syndromes
Significant medical co-morbidities (requiring daily assistance for ADLs)
History of paediatric hip disease (Legg-Calve-Perthes; slipped capital femoral epiphysis)
Ongoing litigation or compensation claims secondary to hip problems
Any other reasons given to exclude the patient
If a patient does not meet the eligibility criteria for the FIRST trial, they may be considered eligible for the FIRST-EPIC sub-study.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Olufemi Ayeni, MD, MSc, FRCSC
Organizational Affiliation
McMaster Univerity
Official's Role
Principal Investigator
Facility Information:
Facility Name
Dalhousie University
City
Halifax
State/Province
Nova Scotia
Country
Canada
Facility Name
McMaster University
City
Hamilton
State/Province
Ontario
ZIP/Postal Code
L8N 3Z5
Country
Canada
Facility Name
Kingston General Hospital
City
Kingston
State/Province
Ontario
Country
Canada
Facility Name
Fowler Kennedy Sports Medicine Clinic
City
London
State/Province
Ontario
Country
Canada
Facility Name
London Health Sciences
City
London
State/Province
Ontario
Country
Canada
Facility Name
St. Michael's Hospital
City
Toronto
State/Province
Ontario
Country
Canada
Facility Name
CHU de Québec, L'Hôtel-Dieu de Québec
City
Quebec City
State/Province
Quebec
Country
Canada
Facility Name
Odense University Hospital
City
Odense
Country
Denmark
Facility Name
Hatanpää Hospital
City
Tampere
ZIP/Postal Code
33900
Country
Finland
Facility Name
Turku University Hospital
City
Turku
ZIP/Postal Code
20540
Country
Finland
12. IPD Sharing Statement
Plan to Share IPD
No
Citations:
PubMed Identifier
14646708
Citation
Ganz R, Parvizi J, Beck M, Leunig M, Notzli H, Siebenrock KA. Femoroacetabular impingement: a cause for osteoarthritis of the hip. Clin Orthop Relat Res. 2003 Dec;(417):112-20. doi: 10.1097/01.blo.0000096804.78689.c2.
Results Reference
background
PubMed Identifier
19341926
Citation
Lincoln M, Johnston K, Muldoon M, Santore R. Combined arthroscopic and modified open approach for cam femoroacetabular impingement: a preliminary experience. Arthroscopy. 2009 Apr;25(4):392-9. doi: 10.1016/j.arthro.2008.12.002.
Results Reference
background
PubMed Identifier
17420508
Citation
Philippon MJ, Stubbs AJ, Schenker ML, Maxwell RB, Ganz R, Leunig M. Arthroscopic management of femoroacetabular impingement: osteoplasty technique and literature review. Am J Sports Med. 2007 Sep;35(9):1571-80. doi: 10.1177/0363546507300258. Epub 2007 Apr 9.
Results Reference
background
PubMed Identifier
18442686
Citation
Larson CM, Giveans MR. Arthroscopic management of femoroacetabular impingement: early outcomes measures. Arthroscopy. 2008 May;24(5):540-6. doi: 10.1016/j.arthro.2007.11.007. Epub 2008 Jan 7.
Results Reference
background
PubMed Identifier
20489213
Citation
Ng VY, Arora N, Best TM, Pan X, Ellis TJ. Efficacy of surgery for femoroacetabular impingement: a systematic review. Am J Sports Med. 2010 Nov;38(11):2337-45. doi: 10.1177/0363546510365530. Epub 2010 May 20.
Results Reference
background
PubMed Identifier
21266277
Citation
Botser IB, Smith TW Jr, Nasser R, Domb BG. Open surgical dislocation versus arthroscopy for femoroacetabular impingement: a comparison of clinical outcomes. Arthroscopy. 2011 Feb;27(2):270-8. doi: 10.1016/j.arthro.2010.11.008.
Results Reference
background
PubMed Identifier
19028166
Citation
Bedi A, Chen N, Robertson W, Kelly BT. The management of labral tears and femoroacetabular impingement of the hip in the young, active patient. Arthroscopy. 2008 Oct;24(10):1135-45. doi: 10.1016/j.arthro.2008.06.001.
Results Reference
background
PubMed Identifier
18984718
Citation
Clohisy JC, Carlisle JC, Beaule PE, Kim YJ, Trousdale RT, Sierra RJ, Leunig M, Schoenecker PL, Millis MB. A systematic approach to the plain radiographic evaluation of the young adult hip. J Bone Joint Surg Am. 2008 Nov;90 Suppl 4(Suppl 4):47-66. doi: 10.2106/JBJS.H.00756. No abstract available.
Results Reference
background
PubMed Identifier
17515374
Citation
Tannast M, Siebenrock KA, Anderson SE. Femoroacetabular impingement: radiographic diagnosis--what the radiologist should know. AJR Am J Roentgenol. 2007 Jun;188(6):1540-52. doi: 10.2214/AJR.06.0921.
Results Reference
background
PubMed Identifier
20410801
Citation
Anderson SE, Siebenrock KA, Mamisch TC, Tannast M. Femoroacetabular impingement magnetic resonance imaging. Top Magn Reson Imaging. 2009 Jun;20(3):123-8. doi: 10.1097/RMR.0b013e3181d99459.
Results Reference
background
PubMed Identifier
12043778
Citation
Notzli HP, Wyss TF, Stoecklin CH, Schmid MR, Treiber K, Hodler J. The contour of the femoral head-neck junction as a predictor for the risk of anterior impingement. J Bone Joint Surg Br. 2002 May;84(4):556-60. doi: 10.1302/0301-620x.84b4.12014.
Results Reference
background
PubMed Identifier
8628042
Citation
Ware J Jr, Kosinski M, Keller SD. A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996 Mar;34(3):220-33. doi: 10.1097/00005650-199603000-00003.
Results Reference
background
PubMed Identifier
12579003
Citation
Christensen CP, Althausen PL, Mittleman MA, Lee JA, McCarthy JC. The nonarthritic hip score: reliable and validated. Clin Orthop Relat Res. 2003 Jan;(406):75-83. doi: 10.1097/01.blo.0000043047.84315.4b.
Results Reference
background
Citation
Schenker ML, Martin R, Weiland DE, Philippon MJ. Current trends in hip arthroscopy: a review of injury diagnosis, techniques and outcome scoring. Current opinion in orthopeadics.2005;16:89-94.
Results Reference
background
PubMed Identifier
19666629
Citation
Thorborg K, Roos EM, Bartels EM, Petersen J, Holmich P. Validity, reliability and responsiveness of patient-reported outcome questionnaires when assessing hip and groin disability: a systematic review. Br J Sports Med. 2010 Dec;44(16):1186-96. doi: 10.1136/bjsm.2009.060889. Epub 2009 Aug 6.
Results Reference
background
PubMed Identifier
21035994
Citation
Lodhia P, Slobogean GP, Noonan VK, Gilbart MK. Patient-reported outcome instruments for femoroacetabular impingement and hip labral pathology: a systematic review of the clinimetric evidence. Arthroscopy. 2011 Feb;27(2):279-86. doi: 10.1016/j.arthro.2010.08.002. Epub 2010 Oct 29.
Results Reference
background
PubMed Identifier
35400136
Citation
Kay J, Simunovic N, Ayeni OR; FIRST Investigators; Bhandari M, Bedi A, Jarvinen T, Musahl V, Naudie D, Seppanen M, Slobogean G, Thabane L, Duong A, Skelly M, Shanmugaraj A, Crouch S, Sprague S, Heels-Ansdell D, Buckingham L, Ramsay T, Lee J, Kousa P, Carsen S, Choudur H, Sim Y, Johnston K, Wong I, Murphy R, Sparavalo S, Whelan D, Khan R, Wood GCA, Howells F, Grant H, Zomar B, Pollock M, Willits K, Firth A, Wanlin S, Remtulla A, Kaniki N, Belzile EL, Turmel S, Jorgensen U, Gam-Pedersen A, Sihvonen R, Raivio Sihvonen M, Toivonen Sihvonen P, Pirjetta Routapohja M. Effect of Osteochondroplasty on Time to Reoperation After Arthroscopic Management of Femoroacetabular Impingement: Analysis of a Randomized Controlled Trial. Orthop J Sports Med. 2022 Apr 5;10(4):23259671211041400. doi: 10.1177/23259671211041400. eCollection 2022 Apr.
Results Reference
derived
PubMed Identifier
32970955
Citation
Femoroacetabular Impingement Randomized Controlled Trial (FIRST) Investigators; Ayeni OR, Karlsson J, Heels-Ansdell D, Thabane L, Musahl V, Simunovic N, Duong A, Bhandari M, Bedi A, Jarvinen T, Naudie D, Seppanen M, Slobogean G, Skelly M, Shanmugaraj A, Crouch S, Sprague S, Buckingham L, Ramsay T, Lee J, Kousa P, Carsen S, Choudur H, Sim Y, Johnston K, Sprague S, Wong I, Murphy R, Sparavalo S, Whelan D, Khan R, Wood GCA, Howells F, Grant H, Naudie D, Zomar B, Pollock M, Willits K, Firth A, Wanlin S, Remtulla A, Kaniki N, Belzile EL, Turmel S, Jorgensen U, Gam-Pedersen A, Hatanpaa T, Sihvonen R, Raivio M, Toivonen P, Routapohja MP. Osteochondroplasty and Labral Repair for the Treatment of Young Adults With Femoroacetabular Impingement: A Randomized Controlled Trial. Am J Sports Med. 2021 Jan;49(1):25-34. doi: 10.1177/0363546520952804. Epub 2020 Sep 24.
Results Reference
derived
PubMed Identifier
30373659
Citation
Simunovic N, Heels-Ansdell D, Thabane L, Ayeni OR; FIRST Investigators. Femoroacetabular Impingement Randomised controlled Trial (FIRST) - a multi-centre randomized controlled trial comparing arthroscopic lavage and arthroscopic osteochondroplasty on patient important outcomes and quality of life in the treatment of young adult (18-50 years) femoroacetabular impingement: a statistical analysis plan. Trials. 2018 Oct 29;19(1):588. doi: 10.1186/s13063-018-2965-0.
Results Reference
derived
PubMed Identifier
25886958
Citation
FIRST Investigators. A multi-centre randomized controlled trial comparing arthroscopic osteochondroplasty and lavage with arthroscopic lavage alone on patient important outcomes and quality of life in the treatment of young adult (18-50) femoroacetabular impingement. BMC Musculoskelet Disord. 2015 Mar 20;16:64. doi: 10.1186/s12891-015-0500-y.
Results Reference
derived
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Femoroacetabular Impingement RandomiSed Controlled Trial
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