Cerebral Blood Perfusion Changes After General Anesthesia for Craniotomy
Brain Neoplasms, Surgery, Hyperemia
About this trial
This is an interventional prevention trial for Brain Neoplasms focused on measuring Cerebral blood flow, Transcranial Doppler, Emergence from general anesthesia
Eligibility Criteria
Inclusion Criteria:
- American Society of Anesthesia (ASA) physical status I or II
- Scheduled for selective supratentorial tumor removal surgery or major abdominal surgery.
Exclusion Criteria:
- Patients with evidence of systemic hypertension, intracranial hypertension, cerebrovascular diseases, other coexisting medical conditions likely to affect cerebral autoregulation.
- Preoperatively planned delayed tracheal extubation.
- Pregnant or nursing women
Sites / Locations
- Huashan Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Patients undergoing craniotomy
Patients undergoing abdominal surgery
Patients undergoing craniotomy who are scheduled for selective supratentorial tumor removal surgery will be randomly chosen and recruited. Transcranial Doppler (TCD) measures,jugular venous bulb catheterization, radial artery catheterization, and tumor removal surgery under general anesthesia will be performed.
Randomly chosen patients undergoing selective abdominal surgery. Transcranial Doppler (TCD) measures,radial artery catheterization, and major abdominal surgery under general anesthesia will be performed.