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Histological Change of The Dentinal-Pulp Complex and Root Resorption

Primary Purpose

Laser, Intrusion, Histology

Status
Completed
Phase
Phase 1
Locations
Colombia
Study Type
Interventional
Intervention
Low power laser in teeth after intrusive movement
Simulated laser in teeth with intrusive movements
Sponsored by
Universidad de Antioquia
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional basic science trial for Laser focused on measuring root resorption, low-power laser, orthodontic tooth movement, pulp changes

Eligibility Criteria

13 Years - 23 Years (Child, Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

  • Patients with first premolar extraction indicated
  • Patients with no sistemic diseases
  • Healthy premolars with completed root and no trauma or restoration

Exclusion Criteria:

  • Sistemics diseased
  • Restoration, trauma in first premolars
  • root uncompleted

Sites / Locations

  • Paula Villa M

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Experimental

Arm Label

Teeth with intrusive movement and low power laser

Teeth with intrusive movements with no laser

Arm Description

Histological changes and root resorption were assesed in Teeth with intrusive movement after a low power laser application

Histological changes and root resorption in Teeth with intrusive movements with no laser

Outcomes

Primary Outcome Measures

Teeth with intrusive movement and low power laser
Histological changes and root resorption were assesed in Teeth with intrusive movement after a low power laser application

Secondary Outcome Measures

Teeth with intrusive movements with no laser exposition
Histological changes and root resorption were assesed in Teeth with intrusive movement with no laser exposition

Full Information

First Posted
July 13, 2012
Last Updated
July 16, 2012
Sponsor
Universidad de Antioquia
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1. Study Identification

Unique Protocol Identification Number
NCT01642693
Brief Title
Histological Change of The Dentinal-Pulp Complex and Root Resorption
Official Title
Histological Changes of The Dentinal-Pulp Complex and Root Resorption in Maxillary Premolars With Intrusive Orthodontic Movements Under a Low Power Laser Effect
Study Type
Interventional

2. Study Status

Record Verification Date
July 2012
Overall Recruitment Status
Completed
Study Start Date
June 2006 (undefined)
Primary Completion Date
May 2008 (Actual)
Study Completion Date
May 2009 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Universidad de Antioquia

4. Oversight

Data Monitoring Committee
Yes

5. Study Description

Brief Summary
The purpose of the study is evaluate the histological changes of the dentinal-pulp complex and root resorption in maxillary premolars with intrusive orthodontic movement under a low power laser effects.
Detailed Description
Orthodontics movements can cause inflamatory changes in the pulp and external inflamatory root resorption, different methods have been suggested to control that changes as the use of the low power laser. The objective of this study is to evaluate the low power laser effect on the inflamatory pulpar change and inflamatory external root resorption in maxillary premolars with intrusive orthodontic movements of 4 ounces during 12 weeks. Total sample were 34 healthy teeth, 16 were used to evaluate the normal standar and 18 were divided in two groups, the experimental group with the low power laser effect had a dose of 18 joules after activations of the orthodontic intrusion and the control group had a simulated effect in the same orthodontic movement. Teeth were extacted after 12 weeks and histological changes were evaluated in the dentinal-pulp complex and the pesence of external inflamatory root resorption. Findins suggest that low power. Laser decreased the inflamatory changes of the dentinal - pulp complex and the severity of the external inflamatory root resorption.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Laser, Intrusion, Histology, Resorption
Keywords
root resorption, low-power laser, orthodontic tooth movement, pulp changes

7. Study Design

Primary Purpose
Basic Science
Study Phase
Phase 1, Phase 2
Interventional Study Model
Parallel Assignment
Masking
Investigator
Allocation
Non-Randomized
Enrollment
34 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Teeth with intrusive movement and low power laser
Arm Type
Experimental
Arm Description
Histological changes and root resorption were assesed in Teeth with intrusive movement after a low power laser application
Arm Title
Teeth with intrusive movements with no laser
Arm Type
Experimental
Arm Description
Histological changes and root resorption in Teeth with intrusive movements with no laser
Intervention Type
Radiation
Intervention Name(s)
Low power laser in teeth after intrusive movement
Intervention Description
Low power laser was aplied to premolar teeth under an intrusive movement to study histological changes and root resorption
Intervention Type
Other
Intervention Name(s)
Simulated laser in teeth with intrusive movements
Intervention Description
Simulated laser in teeth with intrusive movements for histological and root resorption changes
Primary Outcome Measure Information:
Title
Teeth with intrusive movement and low power laser
Description
Histological changes and root resorption were assesed in Teeth with intrusive movement after a low power laser application
Time Frame
12 weeks
Secondary Outcome Measure Information:
Title
Teeth with intrusive movements with no laser exposition
Description
Histological changes and root resorption were assesed in Teeth with intrusive movement with no laser exposition
Time Frame
12 weeks

10. Eligibility

Sex
All
Minimum Age & Unit of Time
13 Years
Maximum Age & Unit of Time
23 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: Patients with first premolar extraction indicated Patients with no sistemic diseases Healthy premolars with completed root and no trauma or restoration Exclusion Criteria: Sistemics diseased Restoration, trauma in first premolars root uncompleted
Facility Information:
Facility Name
Paula Villa M
City
Medellin
State/Province
Antioquia
ZIP/Postal Code
00000
Country
Colombia

12. IPD Sharing Statement

Links:
URL
http://www.udea.edu.co
Description
Related Info

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Histological Change of The Dentinal-Pulp Complex and Root Resorption

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