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Social Network Interventions in Rural Honduras

Primary Purpose

Malnutrition, Dysentery, Social Transmission of Health Behaviors

Status
Completed
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
exposure to vitamin use
exposure to water chlorination
high in-degree
nominated by random
Sponsored by
Harvard University
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional basic science trial for Malnutrition focused on measuring social networks, nutrition, vitamins, chlorine

Eligibility Criteria

15 Years - undefined (Child, Adult, Older Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

  • Residents of Targeted Communities, ages 15 and up

Exclusion Criteria:

  • Children younger than age 15

Sites / Locations

  • Yale University

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm 4

Arm 5

Arm 6

Arm Type

Active Comparator

Active Comparator

Experimental

Experimental

Experimental

Experimental

Arm Label

Random-Cloro

Random-Vitamin

Indegree-Cloro

Indegree-Vitamin

Nominated-Cloro

Nominated-Vitamin

Arm Description

exposure to water chlorination

exposure to vitamin use

high in-degree, exposure to water chlorination

high in-degree, exposure to vitamin use

nominated by random, exposure to water chlorination

nominated by random, exposure to vitamin use

Outcomes

Primary Outcome Measures

Intervention Spread
Use of health product among community members will be tracked.

Secondary Outcome Measures

Full Information

First Posted
August 20, 2012
Last Updated
March 18, 2015
Sponsor
Harvard University
Collaborators
Yale University
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1. Study Identification

Unique Protocol Identification Number
NCT01672580
Brief Title
Social Network Interventions in Rural Honduras
Official Title
Diffusion of Health Interventions Across Social Networks in Honduran Villages
Study Type
Interventional

2. Study Status

Record Verification Date
March 2015
Overall Recruitment Status
Completed
Study Start Date
August 2012 (undefined)
Primary Completion Date
October 2013 (Actual)
Study Completion Date
October 2014 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Harvard University
Collaborators
Yale University

4. Oversight

Data Monitoring Committee
No

5. Study Description

Brief Summary
This project will examine the spread of health interventions with a randomized control trial design by introducing public health interventions in 32 villages in the Honduran Department of Lempira. Based on identified public health needs in the region, namely improved drinking water and diet, this study will provide training on the use of chlorine (sodium hypochlorite) for water purification and multivitamins for nutritional supplementation. In some villages, individuals selected for their social connectedness will be trained and given coupons that can be redeemed for either chlorine bleach or multivitamins, and these persons will be asked to spread this information and distribute coupons to four people of their choosing. In other villages, individuals selected at random will receive the same training, materials, and instructions. A second wave of coupon distribution will provide coupons to those who received a coupon from the original "seed" groups so that they may disperse these coupons further out in the social networks. Over the following months, study investigators will look at how knowledge of these health practices, and uptake or and adherence to the practices, spreads throughout the villages. More specifically, the investigators will examine the speed and extent of spreading of these new health practices after introducing them to three different initial "seed" groups: (1) people chosen on the basis of being named as a friend by many people in their village, (2) people chosen based on being named as a friend by a randomly chosen individual, and (3) a group of randomly chosen individuals. It is hypothesized that spread will occur faster and/or to a greater extent when the intervention is started in groups 1 and 2 versus group 3 (control group).

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Malnutrition, Dysentery, Social Transmission of Health Behaviors
Keywords
social networks, nutrition, vitamins, chlorine

7. Study Design

Primary Purpose
Basic Science
Study Phase
Not Applicable
Interventional Study Model
Factorial Assignment
Masking
Participant
Allocation
Randomized
Enrollment
5773 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Random-Cloro
Arm Type
Active Comparator
Arm Description
exposure to water chlorination
Arm Title
Random-Vitamin
Arm Type
Active Comparator
Arm Description
exposure to vitamin use
Arm Title
Indegree-Cloro
Arm Type
Experimental
Arm Description
high in-degree, exposure to water chlorination
Arm Title
Indegree-Vitamin
Arm Type
Experimental
Arm Description
high in-degree, exposure to vitamin use
Arm Title
Nominated-Cloro
Arm Type
Experimental
Arm Description
nominated by random, exposure to water chlorination
Arm Title
Nominated-Vitamin
Arm Type
Experimental
Arm Description
nominated by random, exposure to vitamin use
Intervention Type
Behavioral
Intervention Name(s)
exposure to vitamin use
Other Intervention Name(s)
Medox Forte
Intervention Description
"Seed" individuals in village are given daily adult multivitamin, with training on use and general nutrition information, along with coupons to distribute to others in village
Intervention Type
Behavioral
Intervention Name(s)
exposure to water chlorination
Other Intervention Name(s)
Clorox
Intervention Description
"Seed" individuals in village are given Clorox bleach for water purification, with training on use and general information on water hygiene, along with coupons to distribute to others in village
Intervention Type
Behavioral
Intervention Name(s)
high in-degree
Intervention Description
"Seed" individuals for starting intervention are chosen on the basis of high (social network) in-degree
Intervention Type
Behavioral
Intervention Name(s)
nominated by random
Intervention Description
"Seed" individuals for starting intervention are chosen on the basis of being named as a friend/alter of a randomly selected individual
Primary Outcome Measure Information:
Title
Intervention Spread
Description
Use of health product among community members will be tracked.
Time Frame
October 2012

10. Eligibility

Sex
All
Minimum Age & Unit of Time
15 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: Residents of Targeted Communities, ages 15 and up Exclusion Criteria: Children younger than age 15
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Nicholas A Christakis, MD, PhD
Organizational Affiliation
Yale University
Official's Role
Principal Investigator
First Name & Middle Initial & Last Name & Degree
Thomas Keegan, PhD
Organizational Affiliation
Yale University
Official's Role
Study Director
Facility Information:
Facility Name
Yale University
City
New Haven
State/Province
Connecticut
ZIP/Postal Code
06517
Country
United States

12. IPD Sharing Statement

Citations:
PubMed Identifier
25952354
Citation
Kim DA, Hwong AR, Stafford D, Hughes DA, O'Malley AJ, Fowler JH, Christakis NA. Social network targeting to maximise population behaviour change: a cluster randomised controlled trial. Lancet. 2015 Jul 11;386(9989):145-53. doi: 10.1016/S0140-6736(15)60095-2. Epub 2015 May 4.
Results Reference
derived

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Social Network Interventions in Rural Honduras

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