Stem Cell Educator Therapy in Alopecia Areata
Alopecia Areata
About this trial
This is an interventional treatment trial for Alopecia Areata focused on measuring Stem Cell Educator, Cord blood stem cells, Immune modulation, Alopecia Areata
Eligibility Criteria
Inclusion Criteria:
- Patients are screened for enrollment in the study if both clinical signs and laboratory tests meet the diagnosis standards recommended by the National Alopecia Areata Foundation (www.naaf.org).
Exclusion Criteria:
- Exclusion criteria are any clinically significant diseases in liver, kidney, and heart. Additional exclusion criteria are no pregnancy, no immunosuppressive medication, no viral diseases or diseases associated with immunodeficiency.
Sites / Locations
- The First Hospital of Hebei Medical UniversityRecruiting
Arms of the Study
Arm 1
Experimental
Stem Cell Educator
The collected lymphocytes are transferred into the device for exposure to CB-SCs, and other blood components are automatically returned to the patient. The Stem Cell Educator functions as part of a closed-loop system that circulates a patient's blood through a blood cell separator, briefly co-cultures the patient's lymphocytes with CB-SCs in vitro, and returns the educated lymphocytes to the patient's circulation. CB-SCs tightly attached to interior surfaces in the device, and only the CB-SC-educated autologous lymphocytes are returned to the subjects. The Stem Cell Educator therapy requires only two venipunctures with minimal pain, and does not introduce stem cells or reagents into patients.