Intraosseous Access in the Emergency Department for Patients With Failed Attempts at Intravenous Access: A Randomized Trial Examining Resource Utilization and Patient Satisfaction
Difficult Peripheral IV Access

About this trial
This is an interventional treatment trial for Difficult Peripheral IV Access focused on measuring Intraosseous (IO) vascular access
Eligibility Criteria
Inclusion Criteria:
- 18 years of age or older
- Hemodynamically stable
- Speaks English
- Able to consent
- Has difficult IV access
Exclusion Criteria:
1. Patients who are younger than 18 years of age, b) lack English fluency c) are unable to give informed consent d) require immediate central venous access e) have a history of osteomyelitis in the only target location of IO access f) have a fracture in the bone of the only target IO site g) have received an IO in the last 24 hours of the only target site h) are allergic to lidocaine i) pregnant or j) require a contrast CT scan as part of their ED care will be excluded.
While pregnant patients may benefit from rescue access the use of lidocaine to anesthetize the medullary space has not been studied in this population.
Sites / Locations
- Hospital of the University of Pennsylvania
- York Hospital
Arms of the Study
Arm 1
Arm 2
No Intervention
Experimental
Standard of care
IO access using EZ-IO®
If you are assigned to this group, ultrasound-guided IV will be used to obtain vascular access.
If you are assigned to this group, you will receive an IO line in the humeral head of the shoulder. IO lines are placed using an FDA-approved device called an EZ-IO®.