EUS-Guided Rendezvous or Direct Interventions Versus Advanced ERCP Techniques for Biliary Access and Therapy
Disorders of Gallbladder, Disorders of Biliary Tract
About this trial
This is an interventional treatment trial for Disorders of Gallbladder focused on measuring Diseases Classified Elsewhere
Eligibility Criteria
Inclusion Criteria:
- Patients able to give informed consent
- Patients referred to participating centers for ERCP with the intent to cannulate the bile duct for therapy
Exclusion Criteria:
- Patients with a bleeding diathesis (INR >1.4, platelets <80, current use of anticoagulant medications)
- Patients whose bile ducts are cannulated using standard methods
- Patients with prior biliary sphincterotomy or endoscopic papilla dilation
- Patients with previous surgical biliary-intestinal operations
- Patients with pancreas divisum
- Patients with indwelling pancreatic or biliary stent placement
- Patients who are pregnant or breast-feeding
Sites / Locations
- California Pacific Medical Center
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
EUS-Rendezvous or direct intervention
Advanced ERCP Biliary Access Techniques
EUS rendezvous or direct intervention involves: (1) using endoscopic-ultrasound technology to access the bile duct with a small needle and manipulate a wire across the biliary orifice and into the duodenum to be then retrieved endoscopically for ERCP (rendezvous ERCP), or (2) using endoscopic-ultrasound technology to directly puncture and perform intended biliary therapy
Advanced ERCP techniques involve the following: precut access sphincterotomy and needle-knife fistulotomy. These are accepted techniques for biliary access in cases of difficult cannulation.