The Effects of Intermittent Epidural Bolus on Fever During Labor Analgesia (EIEBFLA)
Labor Pain, Pain, Neurologic Manifestations
About this trial
This is an interventional treatment trial for Labor Pain focused on measuring Fever, Patient controlled epidural analgesia, Labor analgesia, Epidural analgesia, Combined spinal-epidural analgesia
Eligibility Criteria
Inclusion Criteria:
- Nulliparous women
- Required labor analgesia
- Chinese
- Spontaneous labor
Exclusion Criteria:
- Contraindications for epidural analgesia
- Allergic to opioids and/or local anesthetics
- Failed to performing epidural catheterization
- Organic dysfunction
- Those who were not willing to or could not finish the whole study at any time
- Using or used in the past 14 days of the monoamine oxidase inhibitors
- Alcohol addictive or narcotic dependent patients
- Subjects with a nonvertex presentation or scheduled induction of labor
- Twin gestation and breech presentation
Sites / Locations
- Nanjing Maternal and Child Health Care Hospital Affiliated to Nanjing Medical UniversityRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Arm 6
Arm 7
Arm 8
Active Comparator
Active Comparator
Active Comparator
Active Comparator
Active Comparator
Active Comparator
Active Comparator
Active Comparator
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2
3
4
5
6
7
8
Epidural analgesia (EA) with continuous epidural infusion(CEI)
Combined spinal-epidural analgesia (CSEA) with continuous epidural infusion(CEI)
Epidural analgesia (EA) with intermittent epidural bolus (IEB, 2.5 mL bolused every 15 minutes)
Epidural analgesia (EA) with intermittent epidural bolus (IEB, 5ml bolused every 30 minutes)
Epidural analgesia (EA) with intermittent epidural bolus (IEB, 10ml bolused every 60 minutes)
Combined spinal-epidural analgesia (CSEA) with intermittent epidural bolus (IEB, 2.5 mL bolused every 15 minutes)
Combined spinal-epidural analgesia (CSEA) with intermittent epidural bolus (IEB, 5ml bolused every 30 minutes)
Combined spinal-epidural analgesia (CSEA) with intermittent epidural bolus (IEB, 10ml bolused every 60 minutes)