Treatment of Suspected Cholelithiasis With Nitroglycerin
COLIC, BILIARY TRACT DISEASES
About this trial
This is an interventional treatment trial for COLIC focused on measuring Nitroglycerin, Biliary Colic, Cholelithiasis, Abdominal Pain.
Eligibility Criteria
Inclusion Criteria: Patients with right upper quadrant abdominal pain of less than 24 hours' duration between ages 18 and 60 years of age will be offered treatment with sublingual nitroglycerin or placebo.
Exclusion Criteria: Patients with obstructive hypertrophic cardiomyopathy, pronounced hypovolemia, alcohol use in the last 8 hours, clinical intoxication, STEMI or presumed cardiac chest pain, inferior myocardial infarction with right ventricular involvement, raised intracranial pressure, cardiac tamponade and patients taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), pregnancy or with a known allergy to nitroglycerin will be excluded from the study. Patients unable to give consent will be excluded.
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Sites / Locations
- Naval Medical Center San DiegoRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Placebo Comparator
Sublingual nitroglycerine
placebo
Sublingual nitroglycerine followed by pain assessment and if necessary second dose of sublingual nitroglycerine
sublingual placebo followed by pain assessment and if necessary second dose of sublingual placebo